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PL3638370T3 - Leczenie migreny acetyloleucyną - Google Patents

Leczenie migreny acetyloleucyną

Info

Publication number
PL3638370T3
PL3638370T3 PL18749124T PL18749124T PL3638370T3 PL 3638370 T3 PL3638370 T3 PL 3638370T3 PL 18749124 T PL18749124 T PL 18749124T PL 18749124 T PL18749124 T PL 18749124T PL 3638370 T3 PL3638370 T3 PL 3638370T3
Authority
PL
Poland
Prior art keywords
migraine
leucine
acetyl
treatment
Prior art date
Application number
PL18749124T
Other languages
English (en)
Inventor
Michael Strupp
Mallory Factor
Original Assignee
Intrabio Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=59358204&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3638370(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Intrabio Ltd filed Critical Intrabio Ltd
Publication of PL3638370T3 publication Critical patent/PL3638370T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL18749124T 2017-06-14 2018-06-25 Leczenie migreny acetyloleucyną PL3638370T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1709459.0A GB201709459D0 (en) 2017-06-14 2017-06-14 Treatment for migraine
PCT/IB2018/054676 WO2018229738A1 (en) 2017-06-14 2018-06-25 Treatment for migraine
EP18749124.6A EP3638370B1 (en) 2017-06-14 2018-06-25 Treatment of migraine with acetyl-leucine

Publications (1)

Publication Number Publication Date
PL3638370T3 true PL3638370T3 (pl) 2021-05-17

Family

ID=59358204

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18749124T PL3638370T3 (pl) 2017-06-14 2018-06-25 Leczenie migreny acetyloleucyną

Country Status (26)

Country Link
US (1) US11471434B2 (pl)
EP (1) EP3638370B1 (pl)
JP (1) JP7130739B2 (pl)
KR (1) KR102594130B1 (pl)
CN (1) CN111093772B (pl)
AU (1) AU2018284330B2 (pl)
CA (1) CA3067321A1 (pl)
CY (1) CY1123860T1 (pl)
DK (1) DK3638370T3 (pl)
ES (1) ES2847169T3 (pl)
GB (1) GB201709459D0 (pl)
HR (1) HRP20210108T1 (pl)
HU (1) HUE053089T2 (pl)
IL (1) IL271211B2 (pl)
LT (1) LT3638370T (pl)
MA (1) MA49396B1 (pl)
MD (1) MD3638370T2 (pl)
MX (1) MX387909B (pl)
PL (1) PL3638370T3 (pl)
PT (1) PT3638370T (pl)
RS (1) RS61481B1 (pl)
SG (1) SG11201912146RA (pl)
SI (1) SI3638370T1 (pl)
SM (1) SMT202100037T1 (pl)
WO (1) WO2018229738A1 (pl)
ZA (1) ZA201908087B (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2983441T3 (es) * 2018-02-15 2024-10-23 Intrabio Ltd Acetil-leucina para su uso en el tratamiento de síndrome de las piernas inquietas
CN113348018B (zh) 2018-12-06 2025-04-01 内在生物技术有限公司 乙酰基-亮氨酸的氘代类似物

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8701662L (sv) * 1987-04-22 1988-10-23 Gelder Nico M Van Saett och medel foer att behandla neurologiska sjukdomar, exempelvis migraen genom paaverkan av nervcellerna
US20040127501A1 (en) * 2002-09-24 2004-07-01 Zhengming Chen Therapeutic agents useful for treating pain
US20060063827A1 (en) 2004-09-23 2006-03-23 Yu Ruey J Systemic administration of therapeutic amino acids and N-acetylamino acids
TWI287010B (en) * 2003-06-12 2007-09-21 Euro Celtique Sa Therapeutic agents useful for treating pain
PT1641775E (pt) * 2003-07-03 2009-04-23 Euro Celtique Sa Derivados de 2-piridina-alcino úteis para o tratamento da dor
DE602004021206D1 (de) * 2003-07-24 2009-07-02 Euro Celtique Sa Zur Behandlung oder Vorbeugung von Schmerzen geeignete Heteroaryl-Tetrahydropiperidyl-Verbindungen
ES2317052T3 (es) * 2003-09-22 2009-04-16 Euro-Celtique S.A. Agentes terapeuticos utiles para el tratamiento del dolor.
PL1664041T3 (pl) * 2003-09-22 2008-12-31 Euro Celtique Sa Przydatne do leczenia bólu związki fenylowo-karboksyamidowe
NZ548169A (en) * 2003-12-30 2009-04-30 Euro Celtique Sa Piperazines useful for treating pain
FR2905600B1 (fr) * 2006-09-13 2010-01-15 Pf Medicament Traitement des vertiges par l'acetyl-l-leucine.
TN2010000251A1 (fr) 2010-06-03 2011-11-11 Rekik Raouf N-acetyl-dl-leucine medicament neuro et retino protecteur
EP2585446A4 (en) * 2010-06-22 2013-12-25 Shionogi & Co COMPOUNDS HAVING ANTAGONIST ACTIVITY OF TRPV1 AND USES THEREOF
DK2588130T3 (en) 2010-06-25 2016-10-24 Shire Human Genetic Therapies Cns delivery of therapeutic agents
ES2732818T3 (es) * 2010-11-09 2019-11-26 Mannkind Corp Composición que comprende un agonista de receptores de serotonina y una dicetopiperazina para tratar migrañas
US9394293B2 (en) * 2011-08-10 2016-07-19 Purdue Pharma L.P. TRPV1 antagonists including dihydroxy substituent and uses thereof
EP4501406A3 (en) 2016-04-19 2025-03-26 IntraBio Ltd Acetyl-leucine or a pharmaceutically acceptable salt thereof for improved mobility and cognitive function
LT3416631T (lt) 2016-08-11 2019-08-26 Intrabio Ltd Terapiniai agentai, skirti neurodegeneracinių ligų gydymui
TN2019000032A1 (en) 2016-08-11 2020-07-15 Intrabio Ltd Pharmaceutical compositions and uses directed to lysosomal storage disorders
ES2950452T3 (es) 2017-03-28 2023-10-10 Intrabio Ltd Betahistina, o una sal farmacéuticamente aceptable de la misma, e inhibidor de monoamina oxidasa, para su uso en el tratamiento o la prevención de uno o más síntomas de vértigo en un sujeto
US12458614B2 (en) 2017-10-18 2025-11-04 Intrabio Ltd Therapeutic agents for improved mobility and cognitive function and for treating neurodegenerative diseases and lysosomal storage disorders
CN111542314B (zh) 2017-10-18 2023-11-24 内在生物技术有限公司 神经退行性疾病的治疗剂
ES2983441T3 (es) 2018-02-15 2024-10-23 Intrabio Ltd Acetil-leucina para su uso en el tratamiento de síndrome de las piernas inquietas
CN113348018B (zh) 2018-12-06 2025-04-01 内在生物技术有限公司 乙酰基-亮氨酸的氘代类似物
IL321899A (en) 2019-03-02 2025-09-01 Intrabio Ltd Leucine, acetyl leucine and related analogs for the treatment of disease
EP4650003A2 (en) 2019-06-28 2025-11-19 IntraBio Ltd Combination therapy with acetyl-leucine and miglustat for treating a lysosomal storage disease
WO2021144720A1 (en) 2020-01-13 2021-07-22 Intrabio Ltd Treatment of late-onset neurodegenerative diseases in heterozygous npc1 gene mutation carriers

Also Published As

Publication number Publication date
IL271211B2 (en) 2024-01-01
GB201709459D0 (en) 2017-07-26
JP2020526575A (ja) 2020-08-31
WO2018229738A1 (en) 2018-12-20
IL271211A (en) 2020-01-30
MA49396B1 (fr) 2021-03-31
RS61481B1 (sr) 2021-03-31
SI3638370T1 (sl) 2021-04-30
PT3638370T (pt) 2021-01-26
AU2018284330B2 (en) 2024-03-14
BR112019026660A2 (pt) 2020-07-14
MD3638370T2 (ro) 2021-04-30
IL271211B1 (en) 2023-09-01
EP3638370B1 (en) 2020-11-11
LT3638370T (lt) 2021-03-25
HUE053089T2 (hu) 2021-06-28
MX2019014784A (es) 2021-11-16
CA3067321A1 (en) 2018-12-20
AU2018284330A1 (en) 2020-01-02
CN111093772A (zh) 2020-05-01
RU2020100475A3 (pl) 2021-10-22
SMT202100037T1 (it) 2021-03-15
US11471434B2 (en) 2022-10-18
JP7130739B2 (ja) 2022-09-05
KR20210013518A (ko) 2021-02-04
CY1123860T1 (el) 2022-05-27
EP3638370A1 (en) 2020-04-22
DK3638370T3 (da) 2021-01-25
SG11201912146RA (en) 2020-01-30
CN111093772B (zh) 2023-11-03
ZA201908087B (en) 2024-11-27
ES2847169T3 (es) 2021-08-02
HRP20210108T1 (hr) 2021-03-19
RU2020100475A (ru) 2021-07-14
US20200253905A1 (en) 2020-08-13
KR102594130B1 (ko) 2023-10-24
MA49396A (fr) 2020-04-22
MX387909B (es) 2025-03-19

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