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DK3638293T3 - Sammensætninger til behandling af cancer - Google Patents

Sammensætninger til behandling af cancer Download PDF

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Publication number
DK3638293T3
DK3638293T3 DK18817894.1T DK18817894T DK3638293T3 DK 3638293 T3 DK3638293 T3 DK 3638293T3 DK 18817894 T DK18817894 T DK 18817894T DK 3638293 T3 DK3638293 T3 DK 3638293T3
Authority
DK
Denmark
Prior art keywords
cancer
compositions
treatment
Prior art date
Application number
DK18817894.1T
Other languages
English (en)
Other versions
DK3638293T5 (da
Inventor
Lev Becker
Chang Cui
Original Assignee
Univ Chicago
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Chicago filed Critical Univ Chicago
Publication of DK3638293T3 publication Critical patent/DK3638293T3/da
Application granted granted Critical
Publication of DK3638293T5 publication Critical patent/DK3638293T5/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/54Mixtures of enzymes or proenzymes covered by more than a single one of groups A61K38/44 - A61K38/46 or A61K38/51 - A61K38/53
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/465Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y301/00Hydrolases acting on ester bonds (3.1)
    • C12Y301/26Endoribonucleases producing 5'-phosphomonoesters (3.1.26)
    • C12Y301/26003Ribonuclease III (3.1.26.3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21037Leukocyte elastase (3.4.21.37), i.e. neutrophil-elastase

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
DK18817894.1T 2017-06-15 2018-06-15 Sammensætninger til behandling af cancer DK3638293T5 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762520325P 2017-06-15 2017-06-15
US201762610711P 2017-12-27 2017-12-27
PCT/US2018/037800 WO2018232273A1 (en) 2017-06-15 2018-06-15 Methods and compositions for treating cancer

Publications (2)

Publication Number Publication Date
DK3638293T3 true DK3638293T3 (da) 2023-11-06
DK3638293T5 DK3638293T5 (da) 2024-08-26

Family

ID=64659547

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18817894.1T DK3638293T5 (da) 2017-06-15 2018-06-15 Sammensætninger til behandling af cancer

Country Status (9)

Country Link
US (1) US20210299234A1 (da)
EP (2) EP3638293B1 (da)
JP (3) JP7189160B2 (da)
CN (1) CN111032075A (da)
AU (1) AU2018285710B2 (da)
CA (1) CA3066738A1 (da)
DK (1) DK3638293T5 (da)
ES (1) ES2962985T3 (da)
WO (1) WO2018232273A1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119015448A (zh) * 2018-12-20 2024-11-26 芝加哥大学 与用于癌症疗法的治疗肽相关的方法和组合物
CN116261592A (zh) * 2020-08-18 2023-06-13 昂希莱斯制药公司 经修饰的丝氨酸蛋白酶前蛋白
JP2023545346A (ja) * 2020-08-18 2023-10-30 オンチレス・ファーマ・インコーポレイテッド 改変ブタ膵臓エラスターゼタンパク質
CN112812150A (zh) * 2021-01-29 2021-05-18 深圳海创生物科技有限公司 一种活性环肽、活性环肽组合物及其在制备具有抗氧化或抗炎作用的产品中的应用
CN113736742B (zh) * 2021-09-08 2023-07-21 河南省医药科学研究院 Prtn3基因作为肿瘤免疫治疗中激活细胞毒性免疫细胞靶点的应用
CN115040642B (zh) * 2022-06-30 2025-03-28 德博尔(成都)生物科技有限公司 一种胰弹性蛋白酶的新用途
CN118443941A (zh) * 2024-04-29 2024-08-06 山东大学齐鲁医院 中性粒细胞作为诊疗膀胱癌的靶标的应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3941763A (en) 1975-03-28 1976-03-02 American Home Products Corporation PGlu-D-Met-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-Gly-NH2 and intermediates
US4235871A (en) 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4501728A (en) 1983-01-06 1985-02-26 Technology Unlimited, Inc. Masking of liposomes from RES recognition
US4837028A (en) 1986-12-24 1989-06-06 Liposome Technology, Inc. Liposomes with enhanced circulation time
BR9106732A (pt) * 1990-08-03 1993-08-17 Vertex Pharma Processo catalisado por enzima para preparar um produto selecionado,processos para produzir aspartame,imobilizar uma enzima e imobilizar termolisina,cristais de enzima e de termolisina imobilizadas reticuladas,dispositivos que compreendem as mesmas e biossensor para detectar um analito de interesse em um fluido
US5698518A (en) * 1994-03-30 1997-12-16 Oklahoma Medical Research Foundation Method for regulating inflammation and tumor growth with calmodulin, calmodulin analogues or calmodulin antagonists
AU2003231981A1 (en) * 2002-03-29 2003-10-13 Incyte Corporation Protein modification and maintenance molecules
WO2004031237A1 (en) 2002-09-30 2004-04-15 Oncotherapy Science, Inc. Genes and polypeptides relating to human myeloid leukemia
JP4408615B2 (ja) 2002-10-07 2010-02-03 独立行政法人科学技術振興機構 好酸球カチオン性タンパク質を含有する組成物
US8068990B2 (en) * 2003-03-25 2011-11-29 Hologic, Inc. Diagnosis of intra-uterine infection by proteomic analysis of cervical-vaginal fluids
EP2003196A3 (en) * 2003-06-09 2009-01-07 The Regents of the University of Michigan Compositions and methods for treating and diagnosing cancer
ES2316997T3 (es) * 2003-07-21 2009-04-16 F. Hoffmann-La Roche Ag Uso de la proteina proteinasa 3 (prn3) y del inhibidor de la elastasa leucocitaria (ileu) como un marcador para el cancer colorrectal.
US7432419B2 (en) * 2004-05-14 2008-10-07 Los Alamos National Security, Llc Compositions and methods for the treatment of Pierce's disease
US20060008891A1 (en) * 2004-06-23 2006-01-12 The Government Of Usa As Repersented By The Secretary, Department Of Health And Human Services Cathepsin G-related peptides as modulators of formylpeptide receptors (FPR)
US8501449B2 (en) * 2007-12-04 2013-08-06 Proteon Therapeutics, Inc. Recombinant elastase proteins and methods of manufacturing and use thereof
CN102165075A (zh) * 2008-07-18 2011-08-24 奥洁克公司 用于检测和治疗结肠直肠癌的组合物
GB201121070D0 (en) 2011-12-07 2012-01-18 Isis Innovation composition for delivery of biotherapeutics
WO2016125330A1 (ja) 2015-02-02 2016-08-11 原 英彰 網膜再生促進薬

Also Published As

Publication number Publication date
US20210299234A1 (en) 2021-09-30
JP2020524141A (ja) 2020-08-13
EP3638293A1 (en) 2020-04-22
JP2023022242A (ja) 2023-02-14
EP4292606A3 (en) 2024-02-21
CN111032075A (zh) 2020-04-17
EP4292606B1 (en) 2025-11-12
JP7529754B2 (ja) 2024-08-06
ES2962985T3 (es) 2024-03-22
EP3638293B1 (en) 2023-10-04
EP3638293A4 (en) 2021-03-10
CA3066738A1 (en) 2018-12-20
WO2018232273A1 (en) 2018-12-20
AU2018285710A1 (en) 2020-01-23
JP2024150679A (ja) 2024-10-23
AU2018285710B2 (en) 2025-02-13
JP7189160B2 (ja) 2022-12-13
EP4292606A2 (en) 2023-12-20
DK3638293T5 (da) 2024-08-26

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