DK3686288T3 - Fremgangsmåder og materialer til analyse af homolog rekombinationsdeficiens - Google Patents
Fremgangsmåder og materialer til analyse af homolog rekombinationsdeficiens Download PDFInfo
- Publication number
- DK3686288T3 DK3686288T3 DK20162059.8T DK20162059T DK3686288T3 DK 3686288 T3 DK3686288 T3 DK 3686288T3 DK 20162059 T DK20162059 T DK 20162059T DK 3686288 T3 DK3686288 T3 DK 3686288T3
- Authority
- DK
- Denmark
- Prior art keywords
- analysis
- materials
- methods
- homologous recombination
- recombination deficiency
- Prior art date
Links
- 230000007812 deficiency Effects 0.000 title 1
- 230000006801 homologous recombination Effects 0.000 title 1
- 238000002744 homologous recombination Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Pathology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Catalysts (AREA)
- Carbon And Carbon Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462037764P | 2014-08-15 | 2014-08-15 | |
| US201414507412A | 2014-10-06 | 2014-10-06 | |
| EP15757372.6A EP3180447B1 (en) | 2014-08-15 | 2015-08-17 | Methods and materials for assessing homologous recombination deficiency |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3686288T3 true DK3686288T3 (da) | 2023-05-22 |
Family
ID=54035301
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK20162059.8T DK3686288T3 (da) | 2014-08-15 | 2015-08-17 | Fremgangsmåder og materialer til analyse af homolog rekombinationsdeficiens |
| DK23160447.1T DK4234711T3 (da) | 2014-08-15 | 2015-08-17 | Fremgangsmåder og materialer til vurdering af mangel på homolog rekombination |
| DK15757372.6T DK3180447T3 (da) | 2014-08-15 | 2015-08-17 | Fremgangsmåder og materialer til analyse af homolog rekombinationsdeficiens |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK23160447.1T DK4234711T3 (da) | 2014-08-15 | 2015-08-17 | Fremgangsmåder og materialer til vurdering af mangel på homolog rekombination |
| DK15757372.6T DK3180447T3 (da) | 2014-08-15 | 2015-08-17 | Fremgangsmåder og materialer til analyse af homolog rekombinationsdeficiens |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US10400287B2 (da) |
| EP (4) | EP4234711B1 (da) |
| JP (4) | JP6877334B2 (da) |
| AU (2) | AU2015301390B2 (da) |
| CA (1) | CA2958801A1 (da) |
| DK (3) | DK3686288T3 (da) |
| ES (3) | ES2800673T3 (da) |
| PT (1) | PT3180447T (da) |
| WO (1) | WO2016025958A1 (da) |
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| US20200239969A1 (en) * | 2017-10-16 | 2020-07-30 | The Board Of Regents Of The University Of Texas System | Methods and compositions for use of trex2 as diagnostic and prognostic marker for cancer |
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| CN112410423B (zh) * | 2020-11-03 | 2021-08-13 | 南京世和基因生物技术股份有限公司 | 同源重组缺失的标志物、检测方法以及检测系统 |
| CN112397145A (zh) * | 2020-11-19 | 2021-02-23 | 河南省肿瘤医院 | 一种基于芯片检测的hrd评分计算方法 |
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| CN112820351A (zh) * | 2021-03-01 | 2021-05-18 | 江苏医联生物科技有限公司 | 检测肿瘤患者的突变和hrd评分指导用药的方法 |
| CN112980834B (zh) * | 2021-04-22 | 2021-08-17 | 菁良基因科技(深圳)有限公司 | 一种同源重组修复缺陷参考品及其制备方法和试剂盒 |
| CN114999568B (zh) * | 2021-06-28 | 2023-04-18 | 北京橡鑫生物科技有限公司 | 一种端粒等位基因不平衡tai的计算方法 |
| CN113658638B (zh) * | 2021-08-20 | 2022-06-03 | 江苏先声医学诊断有限公司 | 一种基于ngs平台的同源重组缺陷的检测方法和质控体系 |
| CN113462784B (zh) * | 2021-08-31 | 2021-12-10 | 迈杰转化医学研究(苏州)有限公司 | 一种构建用于同源重组修复缺陷检测的靶标集合的方法 |
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| AU2014248007B2 (en) * | 2013-04-05 | 2020-03-26 | Myriad Genetics, Inc. | Methods and materials for assessing homologous recombination deficiency |
| EP4023765A1 (en) | 2013-12-09 | 2022-07-06 | Institut Curie | Methods for detecting inactivation of the homologous recombination pathway (brca1/2) in human tumors |
| CN105917007A (zh) | 2014-01-16 | 2016-08-31 | 克洛维斯肿瘤有限公司 | Parp抑制剂用以治疗显示杂合性丧失的乳腺癌或卵巢癌患者的用途 |
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