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DK3686288T3 - Fremgangsmåder og materialer til analyse af homolog rekombinationsdeficiens - Google Patents

Fremgangsmåder og materialer til analyse af homolog rekombinationsdeficiens Download PDF

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Publication number
DK3686288T3
DK3686288T3 DK20162059.8T DK20162059T DK3686288T3 DK 3686288 T3 DK3686288 T3 DK 3686288T3 DK 20162059 T DK20162059 T DK 20162059T DK 3686288 T3 DK3686288 T3 DK 3686288T3
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Prior art keywords
analysis
materials
methods
homologous recombination
recombination deficiency
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DK20162059.8T
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English (en)
Inventor
Victor Abkevich
Kirsten Timms
Alexander Gutin
Julia Reid
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Myriad Genetics Inc
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Publication of DK3686288T3 publication Critical patent/DK3686288T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Catalysts (AREA)
  • Carbon And Carbon Compounds (AREA)
DK20162059.8T 2014-08-15 2015-08-17 Fremgangsmåder og materialer til analyse af homolog rekombinationsdeficiens DK3686288T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462037764P 2014-08-15 2014-08-15
US201414507412A 2014-10-06 2014-10-06
EP15757372.6A EP3180447B1 (en) 2014-08-15 2015-08-17 Methods and materials for assessing homologous recombination deficiency

Publications (1)

Publication Number Publication Date
DK3686288T3 true DK3686288T3 (da) 2023-05-22

Family

ID=54035301

Family Applications (3)

Application Number Title Priority Date Filing Date
DK20162059.8T DK3686288T3 (da) 2014-08-15 2015-08-17 Fremgangsmåder og materialer til analyse af homolog rekombinationsdeficiens
DK23160447.1T DK4234711T3 (da) 2014-08-15 2015-08-17 Fremgangsmåder og materialer til vurdering af mangel på homolog rekombination
DK15757372.6T DK3180447T3 (da) 2014-08-15 2015-08-17 Fremgangsmåder og materialer til analyse af homolog rekombinationsdeficiens

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK23160447.1T DK4234711T3 (da) 2014-08-15 2015-08-17 Fremgangsmåder og materialer til vurdering af mangel på homolog rekombination
DK15757372.6T DK3180447T3 (da) 2014-08-15 2015-08-17 Fremgangsmåder og materialer til analyse af homolog rekombinationsdeficiens

Country Status (9)

Country Link
US (4) US10400287B2 (da)
EP (4) EP4234711B1 (da)
JP (4) JP6877334B2 (da)
AU (2) AU2015301390B2 (da)
CA (1) CA2958801A1 (da)
DK (3) DK3686288T3 (da)
ES (3) ES2800673T3 (da)
PT (1) PT3180447T (da)
WO (1) WO2016025958A1 (da)

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CN112980834B (zh) * 2021-04-22 2021-08-17 菁良基因科技(深圳)有限公司 一种同源重组修复缺陷参考品及其制备方法和试剂盒
CN114999568B (zh) * 2021-06-28 2023-04-18 北京橡鑫生物科技有限公司 一种端粒等位基因不平衡tai的计算方法
CN113658638B (zh) * 2021-08-20 2022-06-03 江苏先声医学诊断有限公司 一种基于ngs平台的同源重组缺陷的检测方法和质控体系
CN113462784B (zh) * 2021-08-31 2021-12-10 迈杰转化医学研究(苏州)有限公司 一种构建用于同源重组修复缺陷检测的靶标集合的方法
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CN114242170B (zh) * 2021-12-21 2023-05-09 深圳吉因加医学检验实验室 一种同源重组修复缺陷的评估方法、装置和存储介质
CN114283889B (zh) * 2021-12-27 2024-12-10 深圳吉因加医学检验实验室 一种矫正同源重组修复缺陷评分的方法及装置
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JP2025114740A (ja) 2025-08-05
AU2021273600B2 (en) 2025-02-13
AU2015301390B2 (en) 2021-08-26
CA2958801A1 (en) 2016-02-18
US20190185939A1 (en) 2019-06-20
JP7229297B2 (ja) 2023-02-27
US20250179587A1 (en) 2025-06-05
NZ766822A (en) 2024-08-30
WO2016025958A1 (en) 2016-02-18
AU2015301390A1 (en) 2017-02-02
EP3180447A1 (en) 2017-06-21
EP4234711B1 (en) 2025-05-28
US20170283879A1 (en) 2017-10-05
US12421555B2 (en) 2025-09-23
US10400287B2 (en) 2019-09-03
EP4585701A2 (en) 2025-07-16
JP2017533693A (ja) 2017-11-16
JP6877334B2 (ja) 2021-05-26
NZ728326A (en) 2024-08-30
EP3180447B1 (en) 2020-03-11
EP4234711A2 (en) 2023-08-30
US20230117133A1 (en) 2023-04-20
DK4234711T3 (da) 2025-08-25
EP4234711A3 (en) 2023-09-20
ES2946251T3 (es) 2023-07-14
EP3686288A1 (en) 2020-07-29
JP2021112205A (ja) 2021-08-05
ES3039109T3 (en) 2025-10-17
ES2800673T3 (es) 2021-01-04
EP3686288B1 (en) 2023-03-08
AU2021273600A1 (en) 2021-12-16
EP4585701A3 (en) 2025-08-06
JP7680995B2 (ja) 2025-05-21
JP2023015394A (ja) 2023-01-31
PT3180447T (pt) 2020-06-18
DK3180447T3 (da) 2020-06-15
US12221656B2 (en) 2025-02-11

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