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DK3792378T3 - Fremgangsmåder og anordninger til analyse af partikler - Google Patents

Fremgangsmåder og anordninger til analyse af partikler Download PDF

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Publication number
DK3792378T3
DK3792378T3 DK20197858.2T DK20197858T DK3792378T3 DK 3792378 T3 DK3792378 T3 DK 3792378T3 DK 20197858 T DK20197858 T DK 20197858T DK 3792378 T3 DK3792378 T3 DK 3792378T3
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DK
Denmark
Prior art keywords
particles
analysis
methods
devices
Prior art date
Application number
DK20197858.2T
Other languages
English (en)
Inventor
Jens Huft
Kaston Leung
Anders Klaus
Adi Steif
Carl Lars Genghis Hansen
Loenhout Marinus Theodorus Johannes Van
Bill Kengli Lin
Samuel Alves Jana Rodrigues Aparicio
Sohrab Prakash Shah
Hans Zahn
Original Assignee
Univ British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ British Columbia filed Critical Univ British Columbia
Application granted granted Critical
Publication of DK3792378T3 publication Critical patent/DK3792378T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/505Containers for the purpose of retaining a material to be analysed, e.g. test tubes flexible containers not provided for above
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1093General methods of preparing gene libraries, not provided for in other subgroups
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0887Laminated structure
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/12Specific details about materials
    • B01L2300/123Flexible; Elastomeric
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/14Means for pressure control

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Clinical Laboratory Science (AREA)
  • Dispersion Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Fluid Mechanics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK20197858.2T 2015-02-04 2016-02-04 Fremgangsmåder og anordninger til analyse af partikler DK3792378T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562111755P 2015-02-04 2015-02-04
US201562162039P 2015-05-15 2015-05-15
US201562237690P 2015-10-06 2015-10-06
EP16746018.7A EP3253911B1 (en) 2015-02-04 2016-02-04 Methods and devices for analyzing particles

Publications (1)

Publication Number Publication Date
DK3792378T3 true DK3792378T3 (da) 2023-11-27

Family

ID=56563254

Family Applications (2)

Application Number Title Priority Date Filing Date
DK16746018.7T DK3253911T3 (da) 2015-02-04 2016-02-04 Fremgangsmåder og anordninger til analyse af partikler
DK20197858.2T DK3792378T3 (da) 2015-02-04 2016-02-04 Fremgangsmåder og anordninger til analyse af partikler

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK16746018.7T DK3253911T3 (da) 2015-02-04 2016-02-04 Fremgangsmåder og anordninger til analyse af partikler

Country Status (5)

Country Link
US (3) US10760121B2 (da)
EP (4) EP3792378B1 (da)
CA (1) CA2974632A1 (da)
DK (2) DK3253911T3 (da)
WO (1) WO2016123692A1 (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10017759B2 (en) 2014-06-26 2018-07-10 Illumina, Inc. Library preparation of tagged nucleic acid
US10900065B2 (en) 2014-11-14 2021-01-26 University Of Washington Methods and kits for labeling cellular molecules
WO2016123692A1 (en) 2015-02-04 2016-08-11 The University Of British Columbia Methods and devices for analyzing particles
US11981962B2 (en) * 2016-06-17 2024-05-14 Mayo Foundation For Medical Education And Research Methods and materials for the effective use of combined targeted enrichment of genomic regions and low coverage whole genome sequencing
WO2018183744A1 (en) 2017-03-29 2018-10-04 The Research Foundation For The State University Of New York Microfluidic device and methods
EP3652555B1 (en) * 2017-08-31 2024-03-06 SZ DJI Technology Co., Ltd. A solid state light detection and ranging (lidar) system system and method for improving solid state light detection and ranging (lidar) resolution
CN108363902B (zh) * 2018-01-30 2022-02-25 成都奇恩生物科技有限公司 一种致病遗传变异的精确预测方法
US12377396B2 (en) 2018-02-05 2025-08-05 The Board Of Trustees Of The Leland Stanford Junior University Systems and methods for multiplexed measurements in single and ensemble cells
MX2020009642A (es) 2018-03-16 2021-01-08 Zoetis Services Llc Anticuerpos monoclonales de interleucina-31 para uso veterinario.
KR102672548B1 (ko) 2018-03-16 2024-06-04 조에티스 서비시즈 엘엘씨 인터루킨-31에 대한 펩티드 백신
WO2019217099A1 (en) * 2018-05-08 2019-11-14 President And Fellows Of Harvard College Droplet-based single cell genomic dna sequencing
WO2020006183A1 (en) 2018-06-28 2020-01-02 10X Genomics, Inc. Systems and methods for visualization of single-cell resolution characteristics
WO2020005503A1 (en) * 2018-06-29 2020-01-02 Illumina, Inc. Flow cells
US12331320B2 (en) 2018-10-10 2025-06-17 The Research Foundation For The State University Of New York Genome edited cancer cell vaccines
US20220127597A1 (en) * 2019-02-14 2022-04-28 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Haplotagging - haplotype phasing and single-tube combinatorial barcoding of nucleic acid molecules using bead-immobilized tn5 transposase
WO2020190454A1 (en) * 2019-03-18 2020-09-24 Cellular Research, Inc. Precise delivery of components into fluids
CN114761555A (zh) 2019-08-09 2022-07-15 胡桃钳医疗公司 用于从治疗性组合物中去除材料的制造方法和装置
WO2021097456A1 (en) * 2019-11-17 2021-05-20 The Regents Of The University Of California Guided Microfluidic Flow for Cell Capture, Indexing, and Directed Release
EP4103321A4 (en) 2020-03-30 2023-05-10 Hewlett-Packard Development Company, L.P. FLUID EJECTION MATRIX WITH INWARD-CURVING ANTCHAMBER SIDEWALLS
US20240042442A1 (en) * 2020-12-22 2024-02-08 Hifibio Sas Microfluidic methods and systems
US20230220501A1 (en) * 2022-01-13 2023-07-13 Whitworth University Pathogen detection system
US20250154600A1 (en) * 2022-03-07 2025-05-15 Cedars-Sinai Medical Center Method for detecting cancer and tumor invasiveness using dna palindromes as a biomarker
US20250197924A1 (en) * 2023-12-15 2025-06-19 Amazon Technologies, Inc. Methods for selection and combination of sequencing results from biological samples for neoantigen scoring

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7195670B2 (en) * 2000-06-27 2007-03-27 California Institute Of Technology High throughput screening of crystallization of materials
WO2003048295A1 (en) 2001-11-30 2003-06-12 Fluidigm Corporation Microfluidic device and methods of using same
KR20100028526A (ko) * 2007-02-05 2010-03-12 마이크로칩 바이오테크놀로지스, 인크. 마이크로유체 및 나노유체 장치, 시스템 및 응용
WO2009059430A1 (en) * 2007-11-07 2009-05-14 The University Of British Columbia Microfluidic device and method of using same
US9080211B2 (en) 2008-10-24 2015-07-14 Epicentre Technologies Corporation Transposon end compositions and methods for modifying nucleic acids
US9188593B2 (en) 2010-07-16 2015-11-17 The University Of British Columbia Methods for assaying cellular binding interactions
DK2630263T4 (da) * 2010-10-22 2022-02-14 Cold Spring Harbor Laboratory Varital tælling af nucleinsyrer for at opnå information om antal genomiske kopier
CN102533960B (zh) * 2010-12-31 2014-04-30 深圳华大基因科技有限公司 一种单细胞基因组分析方法及试剂盒
CN103732731A (zh) 2011-05-27 2014-04-16 不列颠哥伦比亚大学 用于高通量分析的微流控细胞捕获和分析设备
US10017759B2 (en) * 2014-06-26 2018-07-10 Illumina, Inc. Library preparation of tagged nucleic acid
US10078778B2 (en) * 2015-01-15 2018-09-18 Massachusetts Institute Of Technology Systems, methods, and apparatus for in vitro single-cell identification and recovery
WO2016123692A1 (en) 2015-02-04 2016-08-11 The University Of British Columbia Methods and devices for analyzing particles

Also Published As

Publication number Publication date
EP3253911A4 (en) 2018-07-04
EP4273262A3 (en) 2023-12-27
US11434530B2 (en) 2022-09-06
EP3792378A1 (en) 2021-03-17
EP3792378B1 (en) 2023-08-23
WO2016123692A1 (en) 2016-08-11
US20230091562A1 (en) 2023-03-23
US20180010179A1 (en) 2018-01-11
EP3253911A1 (en) 2017-12-13
EP4450635A2 (en) 2024-10-23
EP3253911B1 (en) 2021-01-20
EP4450635A3 (en) 2025-01-22
EP4273262A2 (en) 2023-11-08
US20200332357A1 (en) 2020-10-22
US10760121B2 (en) 2020-09-01
DK3253911T3 (da) 2021-04-06
CA2974632A1 (en) 2016-08-11

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