DK3201351T3 - Kaloriefrie sødestoffer og fremgangsmåder til syntetisering - Google Patents
Kaloriefrie sødestoffer og fremgangsmåder til syntetisering Download PDFInfo
- Publication number
- DK3201351T3 DK3201351T3 DK15847668.9T DK15847668T DK3201351T3 DK 3201351 T3 DK3201351 T3 DK 3201351T3 DK 15847668 T DK15847668 T DK 15847668T DK 3201351 T3 DK3201351 T3 DK 3201351T3
- Authority
- DK
- Denmark
- Prior art keywords
- sweetenes
- caloria
- synthesization
- free
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
- A23L2/52—Adding ingredients
- A23L2/60—Sweeteners
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/30—Artificial sweetening agents
- A23L27/33—Artificial sweetening agents containing sugars or derivatives
- A23L27/36—Terpene glycosides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/256—Polyterpene radicals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
- C12N9/1062—Sucrose synthase (2.4.1.13)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
- C12Y204/01013—Sucrose synthase (2.4.1.13)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
- C12Y204/01017—Glucuronosyltransferase (2.4.1.17)
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Nutrition Science (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Seasonings (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Non-Alcoholic Beverages (AREA)
- Enzymes And Modification Thereof (AREA)
- Saccharide Compounds (AREA)
- Peptides Or Proteins (AREA)
- Tea And Coffee (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Fodder In General (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462059498P | 2014-10-03 | 2014-10-03 | |
| US201462098929P | 2014-12-31 | 2014-12-31 | |
| PCT/US2015/053789 WO2016054548A1 (en) | 2014-10-03 | 2015-10-02 | Non-caloric sweeteners and methods for synthesizing |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3201351T3 true DK3201351T3 (da) | 2021-02-22 |
Family
ID=55631622
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15847668.9T DK3201351T3 (da) | 2014-10-03 | 2015-10-02 | Kaloriefrie sødestoffer og fremgangsmåder til syntetisering |
| DK15847221.7T DK3201212T3 (da) | 2014-10-03 | 2015-10-02 | Kaloriefrie sødemidler og fremgangsmåder til syntetisering |
| DK15846977.5T DK3200615T3 (da) | 2014-10-03 | 2015-10-02 | Kaloriefrie sødestoffer og fremgangsmåder til syntetisering |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15847221.7T DK3201212T3 (da) | 2014-10-03 | 2015-10-02 | Kaloriefrie sødemidler og fremgangsmåder til syntetisering |
| DK15846977.5T DK3200615T3 (da) | 2014-10-03 | 2015-10-02 | Kaloriefrie sødestoffer og fremgangsmåder til syntetisering |
Country Status (14)
| Country | Link |
|---|---|
| US (22) | US9783566B2 (da) |
| EP (4) | EP3201212B1 (da) |
| JP (4) | JP6722177B2 (da) |
| KR (4) | KR102526446B1 (da) |
| CN (7) | CN113603736A (da) |
| AU (4) | AU2015327858B2 (da) |
| BR (3) | BR112017006163B1 (da) |
| CA (4) | CA2958434C (da) |
| DK (3) | DK3201351T3 (da) |
| ES (3) | ES2741741T3 (da) |
| HU (2) | HUE045992T2 (da) |
| MX (4) | MX367090B (da) |
| MY (4) | MY183062A (da) |
| WO (4) | WO2016054548A1 (da) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY190346A (en) | 2013-02-06 | 2022-04-15 | Evolva Sa | Methods for improved production of rebaudioside d and rebaudioside m |
| US9522929B2 (en) | 2014-05-05 | 2016-12-20 | Conagen Inc. | Non-caloric sweetener |
| US10264811B2 (en) | 2014-05-19 | 2019-04-23 | Epc Natural Products Co., Ltd. | Stevia sweetener with improved solubility |
| KR102526446B1 (ko) | 2014-10-03 | 2023-04-27 | 코나겐 인크. | 비칼로리 감미료 및 합성 방법 |
| MY193955A (en) | 2014-12-17 | 2022-11-02 | Cargill Inc | Steviol glycoside compounds, compositions for oral ingestion or use, and method for enhancing steviol glycoside solubility |
| BR112017016338A2 (pt) | 2015-01-30 | 2018-03-27 | Evolva Sa | produção de glicosídeos de esteviol em hospedeiros recombinantes |
| US11344051B2 (en) | 2015-04-03 | 2022-05-31 | Dsm Ip Assets B.V. | Steviol glycosides |
| EP3283614B1 (en) * | 2015-04-14 | 2020-07-08 | Conagen Inc. | Production of non-caloric sweeteners using engineered whole-cell catalysts |
| WO2017031424A1 (en) * | 2015-08-20 | 2017-02-23 | Pepsico, Inc. | Preparation of rebaudioside m in a single reaction vessel |
| CN109195457A (zh) | 2016-04-13 | 2019-01-11 | 埃沃尔瓦公司 | 在重组宿主中产生甜菊醇糖苷 |
| EA201990035A1 (ru) | 2016-06-15 | 2019-06-28 | Кодексис, Инк. | Генно-инженерные бета-глюкозидазы и способы глюкозилирования |
| JP2019517812A (ja) * | 2016-06-17 | 2019-06-27 | カーギル インコーポレイテッド | 経口摂取または経口使用のためのステビオールグリコシド組成物 |
| CN109804073B (zh) | 2016-08-12 | 2023-05-16 | 阿迈瑞斯公司 | 用于高效生成瑞鲍迪苷的udp依赖性糖基转移酶 |
| CN110191643B (zh) * | 2016-10-14 | 2023-06-06 | 科纳根公司 | 甜菊醇糖苷的生物合成生产及其工艺 |
| CN116574775A (zh) | 2016-10-21 | 2023-08-11 | 百事可乐公司 | 一种酶法制备瑞鲍迪甙j的方法 |
| CN116515929A (zh) | 2016-10-21 | 2023-08-01 | 百事可乐公司 | 一种酶法制备瑞鲍迪甙n的方法 |
| WO2018093196A1 (ko) * | 2016-11-17 | 2018-05-24 | 서울대학교산학협력단 | 변형 류코노스톡속 균주를 이용한 스테비오사이드 배당체의 합성 방법 및 이에 의하여 제조된 신규한 스테비오사이드 배당체 |
| CN114656452B (zh) * | 2016-12-01 | 2023-01-17 | 阿尔维纳斯运营股份有限公司 | 作为雌激素受体降解剂的四氢萘和四氢异喹啉衍生物 |
| WO2018144679A2 (en) * | 2017-02-03 | 2018-08-09 | Codexis, Inc. | Engineered glycosyltransferases and steviol glycoside glucosylation methods |
| CN111031805B (zh) * | 2017-04-25 | 2023-11-17 | 可口可乐公司 | 二氢查耳酮对甜菊醇糖苷和罗汉果苷甜味剂的甜度和味道改善 |
| CN107164435B (zh) * | 2017-05-27 | 2020-03-31 | 中国药科大学 | 一种莱鲍迪苷ka的制备方法 |
| SG11201911674YA (en) | 2017-06-08 | 2020-01-30 | Suntory Holdings Ltd | Food or beverage with increased sweetness |
| CA3068440A1 (en) | 2017-06-30 | 2019-01-03 | Conagen Inc. | Hydrolysis of steviol glycosides by beta-glucosidase |
| WO2019178116A1 (en) * | 2018-03-12 | 2019-09-19 | Conagen Inc. | Biosynthetic production of steviol glycosides rebaudioside j and rebaudioside n |
| CN112135527B (zh) * | 2018-05-08 | 2023-08-15 | 伊比西(北京)植物药物技术有限公司 | 具有改善风味的甜菊醇糖甙组合物 |
| CN109021038B (zh) * | 2018-06-11 | 2021-07-27 | 江西师范大学 | 一种甜菊糖苷的制备方法 |
| JP7584401B2 (ja) * | 2018-07-30 | 2024-11-15 | テイト アンド ライル ソリューションズ ユー・エス・エー エル・エル・シー | 操作されたグリコシルトランスフェラーゼおよびステビオールグリコシドのグルコシル化方法 |
| JP6887025B2 (ja) * | 2018-08-17 | 2021-06-16 | 邦泰生物工程(深▲セン▼)有限公司 | 安定型ニコチンアミドリボシド組成物及びその調製方法 |
| CN111073923A (zh) * | 2018-10-22 | 2020-04-28 | 山东三元生物科技股份有限公司 | 一种莱鲍迪苷m的酶法制备方法 |
| WO2020097588A1 (en) | 2018-11-09 | 2020-05-14 | Ginkgo Bioworks, Inc. | Biosynthesis of mogrosides |
| AU2019395196B2 (en) * | 2018-12-07 | 2025-07-17 | Suntory Holdings Limited | Coffee beverage having improved quality of taste exhibited by sugar and sweetener |
| CN113163809A (zh) * | 2018-12-07 | 2021-07-23 | 三得利控股株式会社 | 组合物 |
| JP7486433B2 (ja) * | 2018-12-07 | 2024-05-17 | サントリーホールディングス株式会社 | 糖および甘味料の呈する味質が改善したコーヒー飲料 |
| SG11202105334QA (en) * | 2018-12-07 | 2021-06-29 | Suntory Holdings Ltd | Composition |
| BR112021011419A2 (pt) * | 2018-12-12 | 2021-09-08 | Conagen Inc. | Método de produção de rebaudiosídeo r6-2a e/ou r6-2b, r7-2, r6-1 e r6-4a e/ou r6-4b, rebaudiosídeo sintético e produto de consumo oral |
| CN109750072B (zh) * | 2019-01-31 | 2022-04-19 | 南京工业大学 | 一种酶法制备莱鲍迪苷e的方法 |
| EP3799057A1 (en) | 2019-09-25 | 2021-03-31 | Koninklijke Philips N.V. | Prediction tool for patient immune response to a therapy |
| WO2021076924A1 (en) * | 2019-10-16 | 2021-04-22 | Sweegen, Inc. | Steviol glycoside formulations for food and beverages |
| CN110734944B (zh) * | 2019-11-11 | 2023-02-21 | 中化健康产业发展有限公司 | 一步法合成莱鲍迪苷m的方法 |
| CN110872586B (zh) * | 2019-11-11 | 2024-01-30 | 天津大学 | 固定化葡萄糖基转移酶及制备方法及催化生产莱鲍迪苷d的方法 |
| CN110846363B (zh) * | 2019-11-11 | 2023-02-17 | 天津大学 | 一锅法生产莱鲍迪苷d的方法 |
| CN110846305B (zh) * | 2019-11-11 | 2023-11-28 | 中化健康产业发展有限公司 | 一种固定化糖基转移酶催化莱鲍迪苷a生成莱鲍迪苷m的方法 |
| JP2023517332A (ja) * | 2020-03-13 | 2023-04-25 | アミリス, インコーポレイテッド | レバウジオシドm甘味料組成物 |
| JP2023522352A (ja) | 2020-04-20 | 2023-05-30 | ザ コカ・コーラ カンパニー | 香味が増強されたシアメノシドiを含む飲料 |
| US20250320470A1 (en) * | 2020-12-23 | 2025-10-16 | Samyang Corporation | Glycosyltransferase and steviol glucoside preparation method using same |
| JP7210626B2 (ja) * | 2021-02-18 | 2023-01-23 | ペプシコ・インク | 酵素的方法を使用してレバウディオサイドjを調製するための方法 |
| EP4455278A4 (en) * | 2021-12-24 | 2025-11-12 | Samyang Corp | VARIANT OF GLYCOSYLTRANSFERASE, AND PROCESS FOR PREPARING STEVIOL GLYCOSIDES USING IT |
| US12446605B2 (en) | 2022-03-23 | 2025-10-21 | Sweegen, Inc. | Sweeteners |
| CN118064459A (zh) * | 2022-05-27 | 2024-05-24 | 中化健康产业发展有限公司 | 一种催化Reb A生产Reb M的重组糖基转移酶 |
| DE202022103252U1 (de) | 2022-06-09 | 2022-07-01 | Wal Ankita | Eine natürliche Süßstoffzusammensetzung als Süßungsmittel für Diabetes |
| CN116076694B (zh) * | 2022-10-12 | 2024-06-28 | 四川盈嘉合生科技有限公司 | 一种甜菊糖苷甜味剂及其制备方法 |
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| KR102777875B1 (ko) * | 2024-10-22 | 2025-03-13 | 대한민국 | 신규 페디오코커스 속 균주 및 그의 용도 |
| CN119842657B (zh) * | 2025-03-18 | 2025-05-27 | 青岛奔月生物技术有限公司 | 蔗糖合酶突变体及其应用 |
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| US8277862B2 (en) * | 2007-03-14 | 2012-10-02 | Concentrate Manufacturing Company Of Ireland | Beverage products having steviol glycosides and at least one acid |
| PT2350110T (pt) * | 2008-10-03 | 2016-07-28 | Morita Kagaku Kogyo | Novo glicosídeo de esteviol |
| US8501261B2 (en) * | 2010-05-21 | 2013-08-06 | Purecircle Sdn Bhd | High-purity Rebaudioside C and process for purification of the same |
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| EP2645847B1 (en) * | 2010-11-30 | 2018-01-17 | Massachusetts Institute of Technology | Microbial production of natural sweeteners, diterpenoid steviol glycosides |
| EP3792350A1 (en) | 2011-08-08 | 2021-03-17 | Evolva SA | Recombinant production of steviol glycosides |
| ES2787899T3 (es) | 2011-12-19 | 2020-10-19 | Purecircle Sdn Bhd | Métodos para purificar glucósidos de esteviol |
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