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DK3526323T3 - Modificerede meganucleaser der er specifikke for en genkendelsessekvens i hepatitis b virusgenomet - Google Patents

Modificerede meganucleaser der er specifikke for en genkendelsessekvens i hepatitis b virusgenomet Download PDF

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Publication number
DK3526323T3
DK3526323T3 DK17804977.1T DK17804977T DK3526323T3 DK 3526323 T3 DK3526323 T3 DK 3526323T3 DK 17804977 T DK17804977 T DK 17804977T DK 3526323 T3 DK3526323 T3 DK 3526323T3
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Prior art keywords
hepatitis
recognition sequence
virus genome
modified meganucleases
meganucleases specific
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DK17804977.1T
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English (en)
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DK3526323T5 (da
Inventor
Derek Jantz
James Jefferson Smith
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Prec Biosciences Inc
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    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A—HUMAN NECESSITIES
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
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    • C12N2750/14011—Parvoviridae
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12N2800/00—Nucleic acids vectors
    • C12N2800/10—Plasmid DNA
    • C12N2800/106—Plasmid DNA for vertebrates
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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  • Peptides Or Proteins (AREA)
DK17804977.1T 2016-10-14 2017-10-13 Modificerede meganucleaser der er specifikke for en genkendelsessekvens i hepatitis b virusgenomet DK3526323T5 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662408356P 2016-10-14 2016-10-14
US201762452506P 2017-01-31 2017-01-31
US201762527196P 2017-06-30 2017-06-30
US201762527159P 2017-06-30 2017-06-30
PCT/US2017/056638 WO2018071849A2 (en) 2016-10-14 2017-10-13 Engineered meganucleases specific for recognition sequences in the hepatitis b virus genome

Publications (2)

Publication Number Publication Date
DK3526323T3 true DK3526323T3 (da) 2023-06-26
DK3526323T5 DK3526323T5 (da) 2024-09-02

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DK17804977.1T DK3526323T5 (da) 2016-10-14 2017-10-13 Modificerede meganucleaser der er specifikke for en genkendelsessekvens i hepatitis b virusgenomet

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Country Link
US (6) US10662416B2 (da)
EP (2) EP4234691A3 (da)
JP (5) JP6811857B2 (da)
KR (4) KR20240123417A (da)
CN (2) CN117402852A (da)
AU (2) AU2017342536A1 (da)
BR (1) BR112019007450A2 (da)
CA (1) CA3040143A1 (da)
CL (1) CL2019000993A1 (da)
CO (1) CO2019003675A2 (da)
CR (1) CR20190181A (da)
DK (1) DK3526323T5 (da)
DO (1) DOP2019000097A (da)
FI (1) FI3526323T3 (da)
IL (3) IL308894A (da)
MA (1) MA46535A (da)
MX (2) MX2019004349A (da)
PE (1) PE20191353A1 (da)
PH (1) PH12019500788A1 (da)
SG (2) SG11201903042VA (da)
WO (1) WO2018071849A2 (da)

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