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DK3544420T3 - Anvendelse af sammensætninger til organ-/vævskonservering - Google Patents

Anvendelse af sammensætninger til organ-/vævskonservering Download PDF

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Publication number
DK3544420T3
DK3544420T3 DK17829007.8T DK17829007T DK3544420T3 DK 3544420 T3 DK3544420 T3 DK 3544420T3 DK 17829007 T DK17829007 T DK 17829007T DK 3544420 T3 DK3544420 T3 DK 3544420T3
Authority
DK
Denmark
Prior art keywords
organ
compositions
tissue preservation
preservation
tissue
Prior art date
Application number
DK17829007.8T
Other languages
English (en)
Inventor
Andrea Fekete
Ádám Vannay
Ádám Hosszú
Original Assignee
Sigmadrugs Kutato Korlatolt Feleloessegue Tarsasag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigmadrugs Kutato Korlatolt Feleloessegue Tarsasag filed Critical Sigmadrugs Kutato Korlatolt Feleloessegue Tarsasag
Application granted granted Critical
Publication of DK3544420T3 publication Critical patent/DK3544420T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/12Chemical aspects of preservation
    • A01N1/122Preservation or perfusion media
    • A01N1/126Physiologically active agents, e.g. antioxidants or nutrients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/02Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C211/03Monoamines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Dentistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK17829007.8T 2016-11-24 2017-11-24 Anvendelse af sammensætninger til organ-/vævskonservering DK3544420T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HUP1600639 2016-11-24
PCT/HU2017/050051 WO2018096376A1 (en) 2016-11-24 2017-11-24 Compositions for organ preservation

Publications (1)

Publication Number Publication Date
DK3544420T3 true DK3544420T3 (da) 2022-09-05

Family

ID=89720188

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17829007.8T DK3544420T3 (da) 2016-11-24 2017-11-24 Anvendelse af sammensætninger til organ-/vævskonservering

Country Status (11)

Country Link
US (1) US12239125B2 (da)
EP (1) EP3544420B8 (da)
CN (1) CN110337244B (da)
CA (1) CA3044746A1 (da)
DK (1) DK3544420T3 (da)
ES (1) ES2926179T3 (da)
HU (1) HUE060027T2 (da)
IL (1) IL266833B (da)
MA (1) MA46898A (da)
PL (1) PL3544420T3 (da)
WO (1) WO2018096376A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10575515B2 (en) 2010-05-04 2020-03-03 The General Hospital Corporation Methods and compositions for preserving tissues and organs
US10918102B2 (en) 2014-03-13 2021-02-16 The General Hospital Corporation Devices and methods to improve and assess viability of human livers
US12058996B2 (en) 2017-06-14 2024-08-13 The General Hospital Corporation High subzero cryopreservation
US12167729B2 (en) 2018-05-30 2024-12-17 The General Hospital Corporation Cryopreservation of tissues and organs
WO2022241417A1 (en) * 2021-05-10 2022-11-17 The General Hospital Corporation Methods and compositions for extending organ and tissue preservation

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3692835A (en) 1967-04-05 1972-09-19 Jan Van Dijk Pharmacologically active amino-ethyl oximes
NL7503309A (nl) 1975-03-20 1976-09-22 Philips Nv Verbindingen met antidepressieve werking.
NL7503312A (nl) 1975-03-20 1976-09-22 Philips Nv Verbindingen met antidepressieve werking.
NL7503310A (nl) 1975-03-20 1976-09-22 Philips Nv Verbindingen met antidepressieve werking.
US4083978A (en) 1976-01-27 1978-04-11 Egyt Gyogyszervegyeszeti Gyar Oxime ethers
US5086054A (en) 1990-07-31 1992-02-04 Sri International Novel arylcycloalkanepolyalkylamines
US6297212B1 (en) 1994-05-31 2001-10-02 Gregory M. Fahy Growth hormone therapy and related methods and pharmaceutical compositions
IN184685B (da) 1996-02-14 2000-09-23 Nat Inst Immunology
IN186677B (da) 1999-11-12 2001-10-20 Sun Pharmaceutical Ind Ltd
US8765364B2 (en) 2007-05-18 2014-07-01 Lifeline Scientific, Inc. Ex vivo methods for validating substance testing with human organs and/or tissues
RU2460525C2 (ru) * 2008-01-04 2012-09-10 Эл Джи Лайф Сайенсиз Лтд. Производные индола и индазола, обладающие консервирующим действием по отношению к клеткам, тканям и органам
SE533552C2 (sv) * 2008-12-30 2010-10-26 Igeloesa Transplantation Science Ab Förfarande och lösning för behandling av en potentiell organdonator
US8906919B2 (en) 2009-07-09 2014-12-09 Ozteo Pty Ltd Treatment of non-neuronal and non-myocardial cell, tissue and organ damage and associated pain with persistent sodium current blockers
EP2353598A1 (en) 2010-02-04 2011-08-10 Laboratorios Del. Dr. Esteve, S.A. Sigma ligands for use in the prevention and/or treatment of postoperative pain
WO2011123695A1 (en) * 2010-03-31 2011-10-06 Abela Pharmaceuticals, Inc. Dimethy sulfoxxide (dmso) formulations for treating autism
SE534862C2 (sv) * 2010-05-14 2012-01-24 Vivoline Medical Ab Användning av en medicinsk vätska för behandling av ett uttaget organ
US9333205B2 (en) * 2010-07-30 2016-05-10 Nerviano Medical Sciences S.R.L. Isoxazolo-quinazolines as modulators of protein kinase activity
US20140255905A1 (en) 2011-10-03 2014-09-11 Vivoline Medical Ab Medical fluid comprising globulin and its use for preservation of harvested organs
GB201120259D0 (en) * 2011-11-24 2012-01-04 Univ Gent Allogeneic immune response control
US10842794B2 (en) 2014-02-07 2020-11-24 Támogatott Kutatócsoportok Irodája Use of Sigma-1 receptor agonist compounds
ES2848710T3 (es) * 2014-02-07 2021-08-11 Tamogatott Kutatocsoportok Irodaja Nuevo uso de compuestos agonistas del receptor sigma-1
CN104292126B (zh) * 2014-08-14 2016-08-24 广东东阳光药业有限公司 萘衍生物及其在药物上的应用
US20170295776A1 (en) 2016-04-18 2017-10-19 University Of Cincinnati Red blood cell storage solutions, solution additives, and methods for improving the storage of red blood cells

Also Published As

Publication number Publication date
CN110337244B (zh) 2023-07-21
EP3544420B1 (en) 2022-06-22
HUE060027T2 (hu) 2023-01-28
US20190335745A1 (en) 2019-11-07
PL3544420T3 (pl) 2022-11-21
US12239125B2 (en) 2025-03-04
CN110337244A (zh) 2019-10-15
MA46898A (fr) 2019-10-02
ES2926179T3 (es) 2022-10-24
WO2018096376A1 (en) 2018-05-31
IL266833B (en) 2022-01-01
EP3544420A1 (en) 2019-10-02
EP3544420B8 (en) 2022-11-23
CA3044746A1 (en) 2018-05-31
IL266833A (en) 2019-08-29

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