DK3429691T3 - Ikke-vandige, topiske sammensætninger, der omfatter et halogenereret salicylanilid - Google Patents
Ikke-vandige, topiske sammensætninger, der omfatter et halogenereret salicylanilid Download PDFInfo
- Publication number
- DK3429691T3 DK3429691T3 DK17710911.3T DK17710911T DK3429691T3 DK 3429691 T3 DK3429691 T3 DK 3429691T3 DK 17710911 T DK17710911 T DK 17710911T DK 3429691 T3 DK3429691 T3 DK 3429691T3
- Authority
- DK
- Denmark
- Prior art keywords
- water
- compositions including
- halogenated salicylanilide
- topic compositions
- topic
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title 1
- WKEDVNSFRWHDNR-UHFFFAOYSA-N salicylanilide Chemical class OC1=CC=CC=C1C(=O)NC1=CC=CC=C1 WKEDVNSFRWHDNR-UHFFFAOYSA-N 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/203—Retinoic acids ; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/327—Peroxy compounds, e.g. hydroperoxides, peroxides, peroxyacids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/609—Amides, e.g. salicylamide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1604484.4A GB201604484D0 (en) | 2016-03-16 | 2016-03-16 | Topical antibacterial compositions |
| PCT/EP2017/056083 WO2017157997A1 (en) | 2016-03-16 | 2017-03-15 | Non-aqueous topical compositions comprising a halogenated salicylanilide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3429691T3 true DK3429691T3 (da) | 2021-02-08 |
Family
ID=55952410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17710911.3T DK3429691T3 (da) | 2016-03-16 | 2017-03-15 | Ikke-vandige, topiske sammensætninger, der omfatter et halogenereret salicylanilid |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US12036312B2 (da) |
| EP (1) | EP3429691B1 (da) |
| JP (1) | JP2019508463A (da) |
| KR (1) | KR20180123542A (da) |
| CN (1) | CN108883309B (da) |
| AU (1) | AU2017234199A1 (da) |
| BR (1) | BR112018068593A2 (da) |
| CA (1) | CA3013673A1 (da) |
| DK (1) | DK3429691T3 (da) |
| ES (1) | ES2848199T3 (da) |
| GB (1) | GB201604484D0 (da) |
| MX (1) | MX383448B (da) |
| WO (1) | WO2017157997A1 (da) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3338783B1 (en) | 2014-09-12 | 2024-01-24 | UNION therapeutics A/S | Antibacterial use of halogenated salicylanilides |
| GB201509326D0 (en) | 2015-05-29 | 2015-07-15 | Antibio Tx Aps | Novel use |
| GB201615693D0 (en) | 2016-09-15 | 2016-11-02 | Combinatorx Infection Ltd | Combinations |
| GB201713653D0 (en) * | 2017-08-24 | 2017-10-11 | Antibiotx As | Dosage regimen |
| GB201813876D0 (en) | 2018-08-24 | 2018-10-10 | Antibiotx As | Treatment |
| WO2020089467A1 (en) * | 2018-11-02 | 2020-05-07 | UNION therapeutics A/S | Dosage regimen |
| BR112021008417A2 (pt) * | 2018-11-02 | 2021-09-14 | UNION therapeutics A/S | Salicilanilidas halogenadas para tratar os sintomas de dermatite |
| CN109331025A (zh) * | 2018-11-22 | 2019-02-15 | 华中农业大学 | 羟氯扎胺在制备抗猪链球菌的药物中的应用 |
| US11419834B2 (en) | 2019-02-25 | 2022-08-23 | Rhode Island Hospital | Methods for treating diseases or infections caused by or associated with H. pylori using a halogenated salicylanilide |
| JP7657412B2 (ja) * | 2019-09-06 | 2025-04-07 | コンセホ、ナシオナル、デ、インベスティガシオネス、シエンティフィカス、イェ、テクニカス | 局所創傷処置用の医薬組成物 |
| IL296909A (en) | 2020-04-01 | 2022-12-01 | Union Therapeutics As | Formulation |
| US11045434B1 (en) | 2020-04-01 | 2021-06-29 | UNION therapeutics A/S | Niclosamide formulations for treating disease |
| JP2023520542A (ja) | 2020-04-01 | 2023-05-17 | ユニオン・セラピューティクス・アー／エス | 治療薬 |
| CN111743860B (zh) * | 2020-06-30 | 2022-04-05 | 成都中牧生物药业有限公司 | 一种混悬液药物配方 |
| CN111821260B (zh) * | 2020-06-30 | 2022-04-01 | 成都中牧生物药业有限公司 | 用于混悬液药物的生产方法 |
| WO2022169373A1 (en) * | 2021-02-04 | 2022-08-11 | Alan Moana Alexander | Niclosamide compositions having improved bioavailability |
| GB202102488D0 (en) | 2021-02-22 | 2021-04-07 | Union Therapeutics As | Treatment |
| CN113908121B (zh) * | 2021-10-13 | 2023-03-28 | 中国农业科学院上海兽医研究所(中国动物卫生与流行病学中心上海分中心) | 一种氯硝柳胺注射液及其制备和应用 |
Family Cites Families (90)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2731386A (en) | 1951-09-06 | 1956-01-17 | Wallace & Tiernan Company Inc | Antifungal composition |
| US3152039A (en) | 1960-11-23 | 1964-10-06 | Dow Chemical Co | Germicidal compositions |
| FR1340175A (fr) | 1962-03-06 | 1963-10-18 | Procter & Gamble | Nouvelles compositions bactéricides |
| US3674850A (en) | 1969-12-07 | 1972-07-04 | Lever Brothers Ltd | Substituted salicylanilides |
| US3914418A (en) | 1971-09-02 | 1975-10-21 | Merck & Co Inc | Methods of controlling liver fluke infections |
| GB1421589A (en) | 1972-03-07 | 1976-01-21 | Janssen Pharmaceutica Nv | Salicylanilide derivatives |
| DE2557615C2 (de) | 1975-12-20 | 1985-08-14 | Bayer Ag, 5090 Leverkusen | Neue Niclosamid-Suspensionsformulierungen |
| SU597671A1 (ru) | 1976-10-07 | 1978-03-15 | Предприятие П/Я М-5400 | Способ очистки 3,4,5-трибромсалициланилида |
| EP0185490B1 (en) | 1984-12-12 | 1991-09-25 | Euroceltique S.A. | Antibacterial cream |
| US5719197A (en) | 1988-03-04 | 1998-02-17 | Noven Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
| US4883660A (en) | 1988-10-17 | 1989-11-28 | Thames Pharmacal Co., Inc. | Gel bases for pharmaceutical compositions |
| EP0487973B1 (en) | 1990-11-26 | 1996-03-27 | Bayer Corporation | Topical lotion containing Niclosamide |
| WO1996019220A1 (en) | 1994-12-19 | 1996-06-27 | Lauteral Limited | A combination product comprising nitazoxanide and an anti-ulcer agent |
| AUPN814496A0 (en) | 1996-02-19 | 1996-03-14 | Monash University | Dermal penetration enhancer |
| US5837289A (en) | 1996-07-23 | 1998-11-17 | Grasela; John C. | Transdermal delivery of medications using a combination of penetration enhancers |
| JP2002511074A (ja) | 1997-06-11 | 2002-04-09 | バイエル・アクチエンゲゼルシヤフト | 駆虫性組成物 |
| ES2182521T3 (es) | 1998-05-18 | 2003-03-01 | Upjohn Co | Mejoramiento de la actividad de agentes antibacterianos de oxazolidinona mediante derivados de arginina. |
| US6399629B1 (en) | 1998-06-01 | 2002-06-04 | Microcide Pharmaceuticals, Inc. | Efflux pump inhibitors |
| HUP0102782A3 (en) * | 1998-06-19 | 2002-12-28 | Smithkline Beecham Corp | Salycilanilide as inhibitors of transcription factor nf-kb |
| DE19859426A1 (de) | 1998-12-22 | 2000-07-06 | Hassan Jomaa | Verwendung von phosphororganischen Verbindungen zur therapeutischen und prophylaktischen Behandlung von Infektionen |
| WO2001060157A2 (en) | 2000-02-18 | 2001-08-23 | The Procter & Gamble Company | Antibacterial agents and compositions |
| US6774100B2 (en) | 2000-12-06 | 2004-08-10 | Imaginative Research Associates, Inc. | Anhydrous creams, lotions and gels |
| GB2386066A (en) * | 2002-02-28 | 2003-09-10 | Norbrook Lab Ltd | Long-acting parasiticidal composition with improved bioavailability comprising a salicylanilide, a further anti-parasitic compound & a polymeric species |
| RU2227025C2 (ru) | 2002-05-21 | 2004-04-20 | ЗАО "Агроветсервис" | Антипаразитарный препарат широкого спектра действия |
| WO2003103665A1 (ja) | 2002-06-06 | 2003-12-18 | 株式会社医薬分子設計研究所 | 抗アレルギー薬 |
| WO2004006906A2 (en) | 2002-07-15 | 2004-01-22 | Combinatorx, Incorporated | Methods for the treatment of neoplasms |
| JP4446678B2 (ja) | 2003-05-08 | 2010-04-07 | 株式会社ノエビア | 抗菌剤 |
| WO2005007129A2 (en) | 2003-07-17 | 2005-01-27 | Angiotech International Ag | Topical formulations with bioactive components |
| KR20070097291A (ko) | 2003-09-16 | 2007-10-04 | 아스텔라스세이야쿠 가부시키가이샤 | 프로피오니박테리움 아크네스에 대한 항균제 |
| US7666444B2 (en) | 2004-02-02 | 2010-02-23 | Wyeth | Antiparasitic composition |
| US8198326B2 (en) | 2004-09-07 | 2012-06-12 | 3M Innovative Properties Company | Phenolic antiseptic compositions and methods of use |
| US20060222692A1 (en) | 2005-03-31 | 2006-10-05 | Fairfield Clinical Trials Llc | Method and compositions for transdermal administration of antimicrobial medications |
| BRPI0611134A2 (pt) | 2005-06-03 | 2010-08-17 | Acrux Dds Pty Ltd | método e composição para liberação transdérmica de fármaco |
| JP4920206B2 (ja) * | 2005-06-30 | 2012-04-18 | ライオン株式会社 | 外用剤組成物及び貼付剤、並びに薬物の経皮吸収組成物 |
| GB0525093D0 (en) * | 2005-12-09 | 2006-01-18 | Norbrook Lab Ltd | Veterinary composition |
| US7727513B2 (en) | 2005-12-15 | 2010-06-01 | Kimberly-Clark Worldwide, Inc. | Method for screening for bacterial conjunctivitis |
| SI1978936T1 (sl) | 2006-02-03 | 2013-10-30 | Evonik Roehm Gmbh | Farmacevtski sestavki, ki vsebujejo mešanice polimerov in v vodi slabo topna aktivna sredstva |
| US8343962B2 (en) | 2006-03-06 | 2013-01-01 | Nuvo Research Inc. | Topical formulation |
| US20070254036A1 (en) | 2006-04-13 | 2007-11-01 | Besins Healthcare Sa | Treatment of menopause associated symptoms |
| WO2008006848A1 (en) | 2006-07-13 | 2008-01-17 | Galderma Research & Development | Composition comprising a retinoid and benzoyl peroxide |
| WO2008021088A2 (en) | 2006-08-08 | 2008-02-21 | The Regents Of The University Of Californina | Salicylanilides enhance oral delivery of therapeutic peptides |
| US20090016990A1 (en) | 2007-01-24 | 2009-01-15 | Alberte Randall S | Antimicrobial Compositions |
| JP2010528098A (ja) | 2007-05-31 | 2010-08-19 | シントピックス グループ パブリック リミティド カンパニー | ジアルキル・スルホスクシナート及びカルバニリド抗菌剤を含んでなる抗菌製剤 |
| GB0711957D0 (en) * | 2007-06-21 | 2007-08-01 | Syntopix Ltd | Formulations |
| AR068409A1 (es) | 2007-09-14 | 2009-11-18 | Drugtech Corp | Composiciones farmaceuticas, transdermicas sin alcohol |
| WO2009055859A1 (en) | 2007-11-02 | 2009-05-07 | Acrux Dds Pty Ltd | Transdermal delivery system for hormones and steroids |
| ES2324192B1 (es) | 2008-01-30 | 2010-06-17 | PUIG BEAUTY & FASHION GROUP, S.L. | Derivados peptidicos utiles en el tratamiento, cuidado o limpieza de la piel, mucosa, cuero cabelludo o uñas. |
| WO2009111040A1 (en) | 2008-03-07 | 2009-09-11 | Lectec Corporation | Hand sanitizing patch |
| WO2009140215A2 (en) | 2008-05-11 | 2009-11-19 | Geraghty, Erin | Method for treating drug-resistant bacterial and other infections with clioquinol, phanquinone, and related compounds |
| US20100029781A1 (en) | 2008-06-04 | 2010-02-04 | Morris Jerome A | Methods for preparation of anti-acne formulation and compositions prepared thereby |
| EP2143421A1 (en) | 2008-07-07 | 2010-01-13 | Almirall Hermal GmbH | Topical composition for the treatment of actinic keratosis |
| CA2730787A1 (en) | 2008-07-16 | 2010-01-21 | David M. Cohen | Topical drug delivery system |
| US8846646B2 (en) | 2008-10-03 | 2014-09-30 | Winlind Skincare, Llc | Topical treatment of skin infection |
| EP2177208A1 (en) | 2008-10-17 | 2010-04-21 | Ferrer Internacional, S.A. | Pharmaceutical topical compositions |
| GB2465633A (en) * | 2008-12-01 | 2010-06-02 | Syntopix Ltd | Anti-acne formulation |
| GB2456376A (en) * | 2008-12-22 | 2009-07-15 | Syntopix Ltd | Antibacterial/anti-acne formulations comprising a halogenated salicylanilide in combination with one or more anti-acne agents |
| TW201103904A (en) | 2009-06-11 | 2011-02-01 | Hoffmann La Roche | Janus kinase inhibitor compounds and methods |
| WO2011035321A1 (en) * | 2009-09-21 | 2011-03-24 | Duke University | Treatment of wnt/frizzled-related diseases |
| FR2961810B1 (fr) | 2010-06-29 | 2012-07-06 | Galderma Res & Dev | Esters de metronidazole pour traiter la rosacee |
| JP5518595B2 (ja) | 2010-06-30 | 2014-06-11 | 日本エンバイロケミカルズ株式会社 | 工業用防腐・防汚組成物 |
| GB201015079D0 (en) | 2010-09-10 | 2010-10-27 | Helperby Therapeutics Ltd | Novel use |
| DE102010054149A1 (de) | 2010-12-10 | 2012-06-14 | Merck Patent Gmbh | 2-Pyrone |
| BR112013024863A2 (pt) | 2011-03-28 | 2016-12-20 | Yissum Res Dev Co | formulação injetável de liberação sustentada |
| US20140294957A1 (en) | 2011-04-18 | 2014-10-02 | Maxdelbruck-Centrum Fur Molekulare Medizin | Niclosamide for the treatment of cancer metastasis |
| CA2846850C (en) | 2011-08-26 | 2019-12-03 | Ohio University | Combination of d-amino acid and tetrakis hydroxymethyl phosphonium sulfate for treating sulfate reducing bacteria biofilms |
| FR2991173B1 (fr) | 2012-06-04 | 2015-11-06 | Virbac | Composition veterinaire a administration cutanee a base d'oxyclozanide |
| WO2014117236A1 (pt) | 2013-01-30 | 2014-08-07 | Universidade Federal Do Rio De Janeiro - Ufrj | Nanoemulsão óleo em água e seu processo de produção |
| US9446131B2 (en) | 2013-01-31 | 2016-09-20 | Merz Pharmaceuticals, Llc | Topical compositions and methods for making and using same |
| JP7032037B2 (ja) | 2013-02-27 | 2022-03-08 | ロバート バット ローリー | 経皮製剤 |
| US20160136123A1 (en) | 2013-06-14 | 2016-05-19 | Vojo P. Deretic | Treatment of autophagy-related disorders |
| WO2015143654A1 (en) | 2014-03-26 | 2015-10-01 | Merck Sharp & Dohme Corp. | TrkA KINASE INHIBITORS,COMPOSITIONS AND METHODS THEREOF |
| WO2016036839A1 (en) | 2014-09-02 | 2016-03-10 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Compositions and methods for treating gonorrhea |
| EP3338783B1 (en) | 2014-09-12 | 2024-01-24 | UNION therapeutics A/S | Antibacterial use of halogenated salicylanilides |
| CN107635563A (zh) | 2014-11-17 | 2018-01-26 | 维多利亚联结有限公司 | 抗菌化合物 |
| GB201509326D0 (en) | 2015-05-29 | 2015-07-15 | Antibio Tx Aps | Novel use |
| WO2016210247A1 (en) | 2015-06-24 | 2016-12-29 | Duke University | New methods of use for an anti-diarrhea agent |
| AU2016315852B2 (en) | 2015-09-01 | 2023-06-15 | First Wave Bio, Inc. | Methods and compositions for treating conditions associated with an abnormal inflammatory responses |
| CA2955296C (en) | 2016-01-21 | 2024-01-02 | Midmark Corporation | Medical examination table with retractable moving wheels |
| GB201615693D0 (en) | 2016-09-15 | 2016-11-02 | Combinatorx Infection Ltd | Combinations |
| JP7159174B2 (ja) | 2017-02-02 | 2022-10-24 | マックマスター、ユニバーシティー | 抗菌剤用増強剤としての重炭酸塩 |
| US11709169B2 (en) | 2017-02-07 | 2023-07-25 | National Jewish Health | Lipid abnormalities and association with atopic allergic diseases |
| GB201805453D0 (en) | 2018-04-03 | 2018-05-16 | Antibiotx As | Novel use |
| GB201813876D0 (en) | 2018-08-24 | 2018-10-10 | Antibiotx As | Treatment |
| US20210369650A1 (en) | 2018-11-02 | 2021-12-02 | UNION therapeutics A/S | Treatment of inflammatory conditions |
| WO2020176067A1 (en) | 2019-02-25 | 2020-09-03 | Rhode Island Hospital | Methods for treating diseases or infections caused by or associated with h. pylori using a halogenated salicylanilide |
| US11419834B2 (en) | 2019-02-25 | 2022-08-23 | Rhode Island Hospital | Methods for treating diseases or infections caused by or associated with H. pylori using a halogenated salicylanilide |
| US20210114973A1 (en) | 2019-10-18 | 2021-04-22 | First Wave Bio, Inc. | Pharmaceutical formulations |
| JP2023520542A (ja) | 2020-04-01 | 2023-05-17 | ユニオン・セラピューティクス・アー／エス | 治療薬 |
| US11045434B1 (en) | 2020-04-01 | 2021-06-29 | UNION therapeutics A/S | Niclosamide formulations for treating disease |
| IL296909A (en) | 2020-04-01 | 2022-12-01 | Union Therapeutics As | Formulation |
-
2016
- 2016-03-16 GB GBGB1604484.4A patent/GB201604484D0/en not_active Ceased
-
2017
- 2017-03-15 BR BR112018068593-3A patent/BR112018068593A2/pt not_active Application Discontinuation
- 2017-03-15 MX MX2018011249A patent/MX383448B/es unknown
- 2017-03-15 US US16/084,741 patent/US12036312B2/en active Active
- 2017-03-15 JP JP2018548688A patent/JP2019508463A/ja active Pending
- 2017-03-15 EP EP17710911.3A patent/EP3429691B1/en active Active
- 2017-03-15 CA CA3013673A patent/CA3013673A1/en not_active Abandoned
- 2017-03-15 CN CN201780018048.7A patent/CN108883309B/zh not_active Expired - Fee Related
- 2017-03-15 KR KR1020187029769A patent/KR20180123542A/ko not_active Ceased
- 2017-03-15 AU AU2017234199A patent/AU2017234199A1/en not_active Abandoned
- 2017-03-15 ES ES17710911T patent/ES2848199T3/es active Active
- 2017-03-15 WO PCT/EP2017/056083 patent/WO2017157997A1/en not_active Ceased
- 2017-03-15 DK DK17710911.3T patent/DK3429691T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| CN108883309A (zh) | 2018-11-23 |
| WO2017157997A1 (en) | 2017-09-21 |
| ES2848199T3 (es) | 2021-08-05 |
| JP2019508463A (ja) | 2019-03-28 |
| EP3429691B1 (en) | 2020-11-04 |
| MX2018011249A (es) | 2019-09-16 |
| AU2017234199A1 (en) | 2018-08-09 |
| US20190151231A1 (en) | 2019-05-23 |
| US12036312B2 (en) | 2024-07-16 |
| MX383448B (es) | 2025-03-14 |
| EP3429691A1 (en) | 2019-01-23 |
| GB201604484D0 (en) | 2016-04-27 |
| CA3013673A1 (en) | 2017-09-21 |
| CN108883309B (zh) | 2021-08-17 |
| KR20180123542A (ko) | 2018-11-16 |
| BR112018068593A2 (pt) | 2019-04-16 |
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