|
CU22545A1
(es)
|
1994-11-18 |
1999-03-31 |
Centro Inmunologia Molecular |
Obtención de un anticuerpo quimérico y humanizado contra el receptor del factor de crecimiento epidérmico para uso diagnóstico y terapéutico
|
|
GB1458148A
(en)
|
1974-04-19 |
1976-12-08 |
Wyeth John & Brother Ltd |
Carbocyclic-fused ring quinoline derivatives
|
|
JPS57123267A
(en)
|
1981-01-23 |
1982-07-31 |
Kansai Paint Co Ltd |
Thermosetting paint composition
|
|
SE8103843L
(sv)
|
1981-06-18 |
1982-12-19 |
Astra Laekemedel Ab |
Farmaceutisk mixtur
|
|
US4526988A
(en)
|
1983-03-10 |
1985-07-02 |
Eli Lilly And Company |
Difluoro antivirals and intermediate therefor
|
|
DE3587022T2
(de)
|
1984-02-17 |
1993-06-17 |
Genentech Inc |
Menschlicher transformationswachstumsfaktor und vorlaeufer oder fragment hiervon, zellen, dna, vektoren und verfahren zu ihrer herstellung, zusammensetzungen und produkte, die diese enthalten, sowie davon abgeleitete antikoerper und diagnostizierverfahren.
|
|
US4582789A
(en)
|
1984-03-21 |
1986-04-15 |
Cetus Corporation |
Process for labeling nucleic acids using psoralen derivatives
|
|
DE8411409U1
(de)
|
1984-04-11 |
1984-08-30 |
Dr.-Ing. Walter Frohn-Betriebe, 8000 München |
Entgasungsventil fuer lager- und/oder transportbehaelter
|
|
US4563417A
(en)
|
1984-08-31 |
1986-01-07 |
Miles Laboratories, Inc. |
Nucleic acid hybridization assay employing antibodies to intercalation complexes
|
|
EP0183858B1
(de)
|
1984-11-22 |
1988-09-14 |
Holsten-Brauerei AG |
Bier und Verfahren zu dessen Herstellung
|
|
DE3587500T2
(de)
|
1984-12-04 |
1993-12-16 |
Lilly Co Eli |
Tumorbehandlung bei Säugetieren.
|
|
JPS61148115A
(ja)
|
1984-12-21 |
1986-07-05 |
Tooa Eiyoo Kk |
難溶性薬物の徐放性製剤及びその製造法
|
|
JPS62168137A
(ja)
|
1985-12-20 |
1987-07-24 |
Fuji Photo Film Co Ltd |
ハロゲン化銀カラ−写真感光材料およびその処理方法
|
|
CH656535A5
(en)
|
1986-01-24 |
1986-07-15 |
Spirig Ag |
Process for the production of stable pharmaceutical tablets which disintegrate rapidly in water
|
|
JPH07106295B2
(ja)
|
1986-07-22 |
1995-11-15 |
エーザイ株式会社 |
調湿剤
|
|
US4743450A
(en)
|
1987-02-24 |
1988-05-10 |
Warner-Lambert Company |
Stabilized compositions
|
|
CA1339136C
(en)
|
1987-07-01 |
1997-07-29 |
Sailesh Amilal Varia |
Amorphous form of aztreonam
|
|
US5009894A
(en)
|
1988-03-07 |
1991-04-23 |
Baker Cummins Pharmaceuticals, Inc. |
Arrangement for and method of administering a pharmaceutical preparation
|
|
AU4128089A
(en)
|
1988-09-15 |
1990-03-22 |
Rorer International (Overseas) Inc. |
Monoclonal antibodies specific to human epidermal growth factor receptor and therapeutic methods employing same
|
|
US5143854A
(en)
|
1989-06-07 |
1992-09-01 |
Affymax Technologies N.V. |
Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
|
|
US4983615A
(en)
|
1989-06-28 |
1991-01-08 |
Hoechst-Roussel Pharmaceuticals Inc. |
Heteroarylamino- and heteroaryloxypyridinamine compounds which are useful in treating skin disorders
|
|
EP0408496A3
(en)
|
1989-07-12 |
1992-07-01 |
Ciba-Geigy Ag |
Solid dosage form for pharmaceutical substances
|
|
US5120548A
(en)
|
1989-11-07 |
1992-06-09 |
Merck & Co., Inc. |
Swelling modulated polymeric drug delivery device
|
|
US5180818A
(en)
|
1990-03-21 |
1993-01-19 |
The University Of Colorado Foundation, Inc. |
Site specific cleavage of single-stranded dna
|
|
US5210015A
(en)
|
1990-08-06 |
1993-05-11 |
Hoffman-La Roche Inc. |
Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
|
|
DE69132905T2
(de)
|
1990-12-06 |
2002-08-01 |
Affymetrix, Inc. (N.D.Ges.D.Staates Delaware) |
Detektion von Nukleinsäuresequenzen
|
|
GB9105677D0
(en)
|
1991-03-19 |
1991-05-01 |
Ici Plc |
Heterocyclic compounds
|
|
US5367057A
(en)
|
1991-04-02 |
1994-11-22 |
The Trustees Of Princeton University |
Tyrosine kinase receptor flk-2 and fragments thereof
|
|
US5710158A
(en)
|
1991-05-10 |
1998-01-20 |
Rhone-Poulenc Rorer Pharmaceuticals Inc. |
Aryl and heteroaryl quinazoline compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
|
|
US5721237A
(en)
|
1991-05-10 |
1998-02-24 |
Rhone-Poulenc Rorer Pharmaceuticals Inc. |
Protein tyrosine kinase aryl and heteroaryl quinazoline compounds having selective inhibition of HER-2 autophosphorylation properties
|
|
AU658646B2
(en)
|
1991-05-10 |
1995-04-27 |
Rhone-Poulenc Rorer International (Holdings) Inc. |
Bis mono-and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
|
|
JPH04341454A
(ja)
|
1991-05-16 |
1992-11-27 |
Canon Inc |
シート収納装置
|
|
US5750376A
(en)
|
1991-07-08 |
1998-05-12 |
Neurospheres Holdings Ltd. |
In vitro growth and proliferation of genetically modified multipotent neural stem cells and their progeny
|
|
US5211951A
(en)
|
1991-07-24 |
1993-05-18 |
Merck & Co., Inc. |
Process for the manufacture of bioerodible poly (orthoester)s and polyacetals
|
|
JPH05194259A
(ja)
*
|
1991-08-30 |
1993-08-03 |
Mitsubishi Kasei Corp |
抗消化性潰瘍剤
|
|
US5200194A
(en)
|
1991-12-18 |
1993-04-06 |
Alza Corporation |
Oral osmotic device
|
|
CA2137275A1
(en)
|
1992-06-03 |
1993-12-09 |
Richard L. Eckert |
Bandage for continuous application of biologicals
|
|
TW271400B
(da)
*
|
1992-07-30 |
1996-03-01 |
Pfizer |
|
|
GB9221220D0
(en)
|
1992-10-09 |
1992-11-25 |
Sandoz Ag |
Organic componds
|
|
JPH06153952A
(ja)
|
1992-11-26 |
1994-06-03 |
Nobuaki Tamamaki |
微量未知二重鎖ｄｎａ分子の増幅、標識を行うための前処理方法
|
|
GB9323290D0
(en)
|
1992-12-10 |
1994-01-05 |
Zeneca Ltd |
Quinazoline derivatives
|
|
SG45369A1
(en)
|
1993-01-19 |
1998-10-16 |
Warner Lambert Co |
Stable oral ci-981 formulation and process of preparing same
|
|
US6027880A
(en)
|
1995-08-02 |
2000-02-22 |
Affymetrix, Inc. |
Arrays of nucleic acid probes and methods of using the same for detecting cystic fibrosis
|
|
US6156501A
(en)
|
1993-10-26 |
2000-12-05 |
Affymetrix, Inc. |
Arrays of modified nucleic acid probes and methods of use
|
|
JPH07176103A
(ja)
|
1993-12-20 |
1995-07-14 |
Canon Inc |
光磁気記録再生システムならびにこれに用いる磁気ヘッド及び光磁気記録媒体
|
|
GB9326136D0
(en)
|
1993-12-22 |
1994-02-23 |
Erba Carlo Spa |
Biologically active 3-substituted oxindole derivatives useful as anti-angiogenic agents
|
|
IL112249A
(en)
|
1994-01-25 |
2001-11-25 |
Warner Lambert Co |
Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds
|
|
US6811779B2
(en)
|
1994-02-10 |
2004-11-02 |
Imclone Systems Incorporated |
Methods for reducing tumor growth with VEGF receptor antibody combined with radiation and chemotherapy
|
|
JP3660391B2
(ja)
|
1994-05-27 |
2005-06-15 |
株式会社東芝 |
半導体装置の製造方法
|
|
JPH0848078A
(ja)
|
1994-08-05 |
1996-02-20 |
Nippon Paper Ind Co Ltd |
感熱記録体
|
|
GB9510757D0
(en)
|
1994-09-19 |
1995-07-19 |
Wellcome Found |
Therapeuticaly active compounds
|
|
US5656454A
(en)
|
1994-10-04 |
1997-08-12 |
President And Fellows Of Harvard College |
Endothelial cell-specific enhancer
|
|
JP3207058B2
(ja)
|
1994-11-07 |
2001-09-10 |
財団法人国際超電導産業技術研究センター |
超電導体薄膜及びその製造方法
|
|
IL115256A0
(en)
|
1994-11-14 |
1995-12-31 |
Warner Lambert Co |
6-Aryl pyrido (2,3-d) pyrimidines and naphthyridines and their use
|
|
JPH08176138A
(ja)
|
1994-12-19 |
1996-07-09 |
Mercian Corp |
イソクマリン誘導体
|
|
US5948438A
(en)
|
1995-01-09 |
1999-09-07 |
Edward Mendell Co., Inc. |
Pharmaceutical formulations having improved disintegration and/or absorptivity
|
|
US5658374A
(en)
|
1995-02-28 |
1997-08-19 |
Buckman Laboratories International, Inc. |
Aqueous lecithin-based release aids and methods of using the same
|
|
US5624937A
(en)
|
1995-03-02 |
1997-04-29 |
Eli Lilly And Company |
Chemical compounds as inhibitors of amyloid beta protein production
|
|
US6579314B1
(en)
|
1995-03-10 |
2003-06-17 |
C.R. Bard, Inc. |
Covered stent with encapsulated ends
|
|
DE69536015D1
(de)
|
1995-03-30 |
2009-12-10 |
Pfizer Prod Inc |
Chinazolinone Derivate
|
|
GB9508538D0
(en)
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quinazoline derivatives
|
|
US5880141A
(en)
|
1995-06-07 |
1999-03-09 |
Sugen, Inc. |
Benzylidene-Z-indoline compounds for the treatment of disease
|
|
US5654005A
(en)
|
1995-06-07 |
1997-08-05 |
Andrx Pharmaceuticals, Inc. |
Controlled release formulation having a preformed passageway
|
|
JP3290666B2
(ja)
|
1995-06-07 |
2002-06-10 |
ファイザー・インコーポレーテッド |
複素環式の縮合環ピリミジン誘導体
|
|
JPH0923885A
(ja)
|
1995-07-12 |
1997-01-28 |
Dai Ichi Seiyaku Co Ltd |
遺伝子発現ライブラリー及びその製造法
|
|
GB9514265D0
(en)
|
1995-07-13 |
1995-09-13 |
Wellcome Found |
Hetrocyclic compounds
|
|
GB9520822D0
(en)
|
1995-10-11 |
1995-12-13 |
Wellcome Found |
Therapeutically active compounds
|
|
AR004010A1
(es)
|
1995-10-11 |
1998-09-30 |
Glaxo Group Ltd |
Compuestos heterociclicos
|
|
US6346398B1
(en)
|
1995-10-26 |
2002-02-12 |
Ribozyme Pharmaceuticals, Inc. |
Method and reagent for the treatment of diseases or conditions related to levels of vascular endothelial growth factor receptor
|
|
EP0860433B1
(en)
|
1995-11-07 |
2002-07-03 |
Kirin Beer Kabushiki Kaisha |
Quinoline derivatives and quinazoline derivatives inhibiting autophosphorylation of growth factor receptor originating in platelet and pharmaceutical compositions containing the same
|
|
US5849759A
(en)
|
1995-12-08 |
1998-12-15 |
Berlex Laboratories, Inc. |
Naphthyl-substituted benzimidazole derivatives as anti-coagulants
|
|
GB9604361D0
(en)
|
1996-02-29 |
1996-05-01 |
Pharmacia Spa |
4-Substituted pyrrolopyrimidine compounds as tyrosine kinase inhibitors
|
|
JPH09234074A
(ja)
|
1996-03-04 |
1997-09-09 |
Sumitomo Electric Ind Ltd |
アダプター二本鎖ｄｎａ及びそれを用いたｄｎａ増幅方法
|
|
WO1997038984A1
(en)
|
1996-04-17 |
1997-10-23 |
Du Pont Pharmaceuticals Company |
N-(amidinophenyl)-n'-(subst.)-3h-2,4-benzodiazepin-3-one derivatives as factor xa inhibitors
|
|
AU3568897A
(en)
|
1996-06-07 |
1998-01-05 |
Eos Biotechnology, Inc. |
Immobilised linear oligonucleotide arrays
|
|
EP0912175A4
(en)
|
1996-06-28 |
1999-09-08 |
Merck & Co Inc |
FIBRINOGENIC RECEPTOR ANTAGONISTS
|
|
EP0912559B1
(en)
|
1996-07-13 |
2002-11-06 |
Glaxo Group Limited |
Fused heterocyclic compounds as protein tyrosine kinase inhibitors
|
|
HRP970371A2
(en)
|
1996-07-13 |
1998-08-31 |
Kathryn Jane Smith |
Heterocyclic compounds
|
|
DE69718472T2
(de)
|
1996-07-13 |
2003-11-06 |
Glaxo Group Ltd., Greenford |
Bicyclische heteroaromatische verbindungen als protein tyrosine kinase inhibitoren
|
|
JPH10147524A
(ja)
|
1996-09-20 |
1998-06-02 |
Nippon Kayaku Co Ltd |
フォルスコリン誘導体含有経口製剤及び医薬製剤の製法
|
|
US6809097B1
(en)
|
1996-09-25 |
2004-10-26 |
Zeneca Limited |
Quinoline derivatives inhibiting the effect of growth factors such as VEGF
|
|
DE69722019T2
(de)
|
1996-09-30 |
2003-11-27 |
Nihon Nohyaku Co., Ltd. |
1,2,3-thiadiazol-derivate und ihre salze, mittel zur kontrolle von krankheiten in landwirtschaft und gartenbau und eine methode zu ihrer anwendung
|
|
JPH10114655A
(ja)
|
1996-10-09 |
1998-05-06 |
Kyowa Hakko Kogyo Co Ltd |
固形製剤
|
|
EP0837063A1
(en)
|
1996-10-17 |
1998-04-22 |
Pfizer Inc. |
4-Aminoquinazoline derivatives
|
|
BR9713552A
(pt)
|
1996-11-27 |
2000-01-25 |
Pfizer |
Derivados de pirimidina bicìclicos condensados
|
|
TW486370B
(en)
|
1996-12-25 |
2002-05-11 |
Yamanouchi Pharma Co Ltd |
Rapidly disintegrable pharmaceutical composition
|
|
EP1014971A1
(en)
|
1997-01-29 |
2000-07-05 |
Eli Lilly And Company |
Treatment for premenstrual dysphoric disorder
|
|
JP3040486U
(ja)
|
1997-02-13 |
1997-08-19 |
有限会社ザップ |
フィッシングジャケット
|
|
CO4950519A1
(es)
|
1997-02-13 |
2000-09-01 |
Novartis Ag |
Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion
|
|
DK0968206T3
(da)
|
1997-02-19 |
2007-03-26 |
Berlex Inc |
N-heterocykliske derivater som NOS-inhibitorer
|
|
US6090556A
(en)
|
1997-04-07 |
2000-07-18 |
Japan Science & Technology Corporation |
Method for quantitatively determining the expression of a gene
|
|
AU7526798A
(en)
|
1997-04-18 |
1998-11-27 |
Smithkline Beecham Plc |
Acetamide and urea derivatives, process for their preparation and their use in the treatment of cns disorders
|
|
JPH10316576A
(ja)
|
1997-05-13 |
1998-12-02 |
Nissui Pharm Co Ltd |
キトサン含有錠剤
|
|
DE1019040T1
(de)
|
1997-05-23 |
2001-02-08 |
Bayer Corp., West Haven |
Hemmung von p38 kinase aktivität durch arylharnstoff
|
|
ES2155995T3
(es)
|
1997-06-10 |
2001-06-01 |
Synthon Bv |
Compuestos de 4-fenilpiperidina.
|
|
US6093742A
(en)
|
1997-06-27 |
2000-07-25 |
Vertex Pharmaceuticals, Inc. |
Inhibitors of p38
|
|
WO1999001738A2
(en)
|
1997-06-30 |
1999-01-14 |
University Of Maryland, Baltimore |
Heparin binding-epidermal growth factor in the diagnosis of interstitial cystitis
|
|
BE1011251A3
(fr)
|
1997-07-03 |
1999-06-01 |
Ucb Sa |
Compositions pharmaceutiques administrables par voie orale, comprenant une substance active et une cyclodextrine.
|
|
CO4940418A1
(es)
|
1997-07-18 |
2000-07-24 |
Novartis Ag |
Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso
|
|
JP3765918B2
(ja)
|
1997-11-10 |
2006-04-12 |
パイオニア株式会社 |
発光ディスプレイ及びその駆動方法
|
|
JP4194678B2
(ja)
|
1997-11-28 |
2008-12-10 |
キリンファーマ株式会社 |
キノリン誘導体およびそれを含む医薬組成物
|
|
ATE529109T1
(de)
|
1997-12-22 |
2011-11-15 |
Bayer Healthcare Llc |
Hemmung der p38 kinase aktivität durch substituierte heterocyclische harnstoffe
|
|
DE69836563T2
(de)
|
1997-12-22 |
2007-05-16 |
Bayer Pharmaceuticals Corp., West Haven |
INHIBIERUNG DER p38 KINASE-AKTIVITÄT DURCH DIE VERWENDUNG VON ARYL- UND HETEROARYL-SUBSTITUIERTEN HARNSTOFFEN
|
|
HU227711B1
(en)
|
1997-12-22 |
2011-12-28 |
Bayer Healthcare Llc |
Inhibition of raf kinase using symmetrical and unsymmetrical substituted diphenyl ureas and pharmaceutical compositions containing them
|
|
NZ505844A
(en)
|
1997-12-22 |
2003-10-31 |
Bayer Ag |
Inhibition of raf kinase using substituted heterocyclic ureas
|
|
GB9800569D0
(en)
|
1998-01-12 |
1998-03-11 |
Glaxo Group Ltd |
Heterocyclic compounds
|
|
GB9800575D0
(en)
|
1998-01-12 |
1998-03-11 |
Glaxo Group Ltd |
Heterocyclic compounds
|
|
CA2322162A1
(en)
|
1998-02-25 |
1999-09-02 |
Genetics Institute, Llc |
Inhibitors of phospholipase enzymes
|
|
DE69901938T3
(de)
|
1998-03-06 |
2012-08-02 |
Aptalis Pharma S.R.L. |
Schnell zerfallende tablette
|
|
DE19814257A1
(de)
|
1998-03-31 |
1999-10-07 |
Asta Medica Ag |
Brauseformulierungen
|
|
JPH11322596A
(ja)
|
1998-05-12 |
1999-11-24 |
Shionogi & Co Ltd |
白金錯体および環状リン酸エステルアミドを含有する抗癌剤
|
|
UA60365C2
(uk)
|
1998-06-04 |
2003-10-15 |
Пфайзер Продактс Інк. |
Похідні ізотіазолу, спосіб їх одержання, фармацевтична композиція та спосіб лікування гіперпроліферативного захворювання у ссавця
|
|
US6653341B1
(en)
|
1998-06-17 |
2003-11-25 |
Eisai Co., Ltd. |
Methods and compositions for use in treating cancer
|
|
US8097648B2
(en)
|
1998-06-17 |
2012-01-17 |
Eisai R&D Management Co., Ltd. |
Methods and compositions for use in treating cancer
|
|
IL139960A0
(en)
|
1998-06-17 |
2002-02-10 |
Eisai Co Ltd |
Macrocylic analogs and methods of their use and preparation
|
|
IL141762A0
(en)
|
1998-10-01 |
2002-03-10 |
Novartis Ag |
New oral formulations
|
|
WO2000031048A1
(en)
|
1998-11-19 |
2000-06-02 |
Warner-Lambert Company |
N-[4-(3-chloro-4-fluoro-phenylamino)-7-(3-morpholin-4-yl-propoxy)-quinazolin-6-yl]-acrylamide, an irreversible inhibitor of tyrosine kinases
|
|
WO2000042012A1
(en)
|
1999-01-13 |
2000-07-20 |
Bayer Corporation |
φ-CARBOXYARYL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS
|
|
UA73492C2
(en)
|
1999-01-19 |
2005-08-15 |
|
Aromatic heterocyclic compounds as antiinflammatory agents
|
|
ATE253051T1
(de)
|
1999-01-22 |
2003-11-15 |
Kirin Brewery |
Chinolinderivate und chinazolinderivate
|
|
UA71945C2
(en)
|
1999-01-27 |
2005-01-17 |
Pfizer Prod Inc |
Substituted bicyclic derivatives being used as anticancer agents
|
|
JP3270834B2
(ja)
|
1999-01-27 |
2002-04-02 |
ファイザー・プロダクツ・インク |
抗がん剤として有用なヘテロ芳香族二環式誘導体
|
|
BRPI0017548B8
(pt)
|
1999-02-10 |
2023-05-02 |
Astrazeneca Ab |
Composto
|
|
GB9904103D0
(en)
|
1999-02-24 |
1999-04-14 |
Zeneca Ltd |
Quinoline derivatives
|
|
JP2000328080A
(ja)
|
1999-03-12 |
2000-11-28 |
Shin Etsu Chem Co Ltd |
シートベルト用低摩擦化処理剤
|
|
RS49836B
(sr)
|
1999-03-31 |
2008-08-07 |
Pfizer Products Inc., |
Postupci i intermedijeri za dobijanje anti-kancernih jedinjenja
|
|
CN1308347C
(zh)
|
1999-04-28 |
2007-04-04 |
德克萨斯大学董事会 |
用于通过选择性抑制vegf来治疗癌症的组合物和方法
|
|
AU4778500A
(en)
|
1999-05-20 |
2000-12-12 |
Takeda Chemical Industries Ltd. |
Composition containing ascorbic acid salt
|
|
JP4304357B2
(ja)
|
1999-05-24 |
2009-07-29 |
独立行政法人理化学研究所 |
完全長ｃＤＮＡライブラリーの作成法
|
|
PE20010306A1
(es)
|
1999-07-02 |
2001-03-29 |
Agouron Pharma |
Compuestos de indazol y composiciones farmaceuticas que los contienen utiles para la inhibicion de proteina kinasa
|
|
JP2001047890A
(ja)
|
1999-08-06 |
2001-02-20 |
Toyota Motor Corp |
車両用パワープラントの制御装置
|
|
AU6762400A
(en)
|
1999-08-12 |
2001-03-13 |
Cor Therapeutics, Inc. |
Inhibitors of factor xa
|
|
CO5200835A1
(es)
|
1999-09-28 |
2002-09-27 |
Bayer Corp |
Piridinas y piridacinas sustituidas con actividad de inhibicion de angiogenesis
|
|
UA75054C2
(uk)
|
1999-10-13 |
2006-03-15 |
Бьорінгер Інгельхайм Фарма Гмбх & Ко. Кг |
Заміщені в положенні 6 індолінони, їх одержання та їх застосування як лікарського засобу
|
|
US6762180B1
(en)
|
1999-10-13 |
2004-07-13 |
Boehringer Ingelheim Pharma Kg |
Substituted indolines which inhibit receptor tyrosine kinases
|
|
JP2001131071A
(ja)
|
1999-10-29 |
2001-05-15 |
Meiji Seika Kaisha Ltd |
非晶質および非晶質を含有する医薬組成物
|
|
US20080241835A1
(en)
|
1999-11-01 |
2008-10-02 |
Genentech, Inc. |
Differentially expressed genes involved in angiogenesis, the polypeptides encoded thereby, and methods of using the same
|
|
AU784338B2
(en)
|
1999-11-01 |
2006-03-16 |
Curagen Corporation |
Differentially expressed genes involved in angiogenesis, the polypeptides encoded thereby, and methods of using the same
|
|
WO2001036403A1
(en)
|
1999-11-16 |
2001-05-25 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Urea derivatives as anti-inflammatory agents
|
|
UA75055C2
(uk)
|
1999-11-30 |
2006-03-15 |
Пфайзер Продактс Інк. |
Похідні бензоімідазолу, що використовуються як антипроліферативний засіб, фармацевтична композиція на їх основі
|
|
ES2267605T3
(es)
|
1999-12-22 |
2007-03-16 |
Sugen, Inc. |
Uso de compuestos de indolinona para la fabricacion de productos farmaceuticos destinados a modular la funcion de la c-kit-tirosina-proteina-quinasa.
|
|
AU2223201A
(en)
|
1999-12-24 |
2001-07-09 |
Kirin Beer Kabushiki Kaisha |
Quinoline and quinazoline derivatives and drugs containing the same
|
|
US7005430B2
(en)
|
1999-12-24 |
2006-02-28 |
Kyowa Hakko Kogyo Co., Ltd. |
Fused purine derivatives
|
|
US6573293B2
(en)
|
2000-02-15 |
2003-06-03 |
Sugen, Inc. |
Pyrrole substituted 2-indolinone protein kinase inhibitors
|
|
JP3657203B2
(ja)
|
2000-04-21 |
2005-06-08 |
エーザイ株式会社 |
銅クロロフィリン塩含有液剤組成物
|
|
CN1116047C
(zh)
|
2000-06-05 |
2003-07-30 |
华中科技大学 |
用泥鳅制成的护肝功能食品及其制备方法
|
|
JP2004512023A
(ja)
|
2000-06-09 |
2004-04-22 |
コリクサ コーポレイション |
結腸癌の治療および診断のための組成物および方法
|
|
AU2001277621A1
(en)
|
2000-08-09 |
2002-03-04 |
Astrazeneca Ab |
Antiangiogenic bicyclic derivatives
|
|
WO2002032872A1
(fr)
|
2000-10-20 |
2002-04-25 |
Eisai Co., Ltd. |
Composes a noyau aromatique azote
|
|
TWI283575B
(en)
|
2000-10-31 |
2007-07-11 |
Eisai Co Ltd |
Medicinal compositions for concomitant use as anticancer agent
|
|
EP1339458B1
(en)
|
2000-11-22 |
2007-08-15 |
Novartis AG |
Combination comprising an agent decreasing vegf activity and an agent decreasing egf activity
|
|
EP1341771A2
(en)
|
2000-11-29 |
2003-09-10 |
Glaxo Group Limited |
Benzimidazole derivatives useful as tie-2 and/or vegfr-2 inhibitors
|
|
US6544552B2
(en)
|
2001-01-11 |
2003-04-08 |
Particle And Coating Technologies, Inc. |
Method of producing porous tablets with improved dissolution properties
|
|
CA2439402A1
(en)
|
2001-03-02 |
2002-09-12 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
Pcr method
|
|
AU2002254152A1
(en)
|
2001-03-08 |
2002-09-24 |
Millennium Pharmaceuticals |
(homo) piperazine substituted quinolines for inhibiting the phosphorylation of kinases
|
|
PL363991A1
(en)
|
2001-04-06 |
2004-11-29 |
Wyeth |
Antineoplastic combinations such as rapamycin together with gemcitabine or fluorouracil
|
|
EP1379545A2
(de)
|
2001-04-19 |
2004-01-14 |
Gesellschaft für biotechnologische Forschung mbH (GBF) |
Verfahren zur herstellung stabiler, regenerierbarer antikörper-arrays
|
|
PL209822B1
(pl)
|
2001-04-27 |
2011-10-31 |
Kirin Pharma Kk |
Pochodna chinoliny lub chinazoliny, zawierająca ją kompozycja farmaceutyczna i zastosowanie
|
|
JP3602513B2
(ja)
|
2001-04-27 |
2004-12-15 |
麒麟麦酒株式会社 |
アゾリル基を有するキノリン誘導体およびキナゾリン誘導体
|
|
JP2003026576A
(ja)
|
2001-05-09 |
2003-01-29 |
Eisai Co Ltd |
味覚改善製剤
|
|
US6812341B1
(en)
|
2001-05-11 |
2004-11-02 |
Ambion, Inc. |
High efficiency mRNA isolation methods and compositions
|
|
PT1392313E
(pt)
|
2001-05-16 |
2007-07-17 |
Novartis Ag |
Combinação que compreende n - ( 5- [ 4- ( metil-piperazinomrtil ) - benxoilamido ] - 2 -metilfenil ) - 4 -( 3 - piridil ) - 2 - pirimidina-amina e um agente quimioterapêutico
|
|
US6599902B2
(en)
|
2001-05-30 |
2003-07-29 |
Sugen, Inc. |
5-aralkysufonyl-3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives as kinase inhibitors
|
|
KR100883731B1
(ko)
|
2001-06-22 |
2009-02-12 |
기린 파마 가부시끼가이샤 |
간세포 증식 인자 수용체 자기 인산화를 저해하는 퀴놀린유도체 및 퀴나졸린 유도체 및 이들을 함유하는 의약 조성물
|
|
US20030013208A1
(en)
|
2001-07-13 |
2003-01-16 |
Milagen, Inc. |
Information enhanced antibody arrays
|
|
GB0117144D0
(en)
|
2001-07-13 |
2001-09-05 |
Glaxo Group Ltd |
Process
|
|
JP4827154B2
(ja)
|
2001-07-25 |
2011-11-30 |
株式会社オーイズミ |
遊技装置
|
|
JP3088018U
(ja)
|
2001-08-02 |
2002-08-30 |
ユーエス工業株式会社 |
垂木支持用ブラケットを備えたパイプバンド
|
|
GB0119467D0
(en)
|
2001-08-09 |
2001-10-03 |
Smithkline Beecham Plc |
Novel compound
|
|
WO2003023360A2
(en)
|
2001-09-10 |
2003-03-20 |
Meso Scale Technologies, Llc |
Methods and apparatus for conducting multiple measurements on a sample
|
|
US20040242601A1
(en)
|
2001-09-20 |
2004-12-02 |
Alain Moussy |
Use of potent, selective and non toxic c-kit inhibitors for treating interstitial cystitis
|
|
US6765012B2
(en)
|
2001-09-27 |
2004-07-20 |
Allergan, Inc. |
3-(Arylamino)methylene-1,3-dihydro-2H-indol-2-ones as kinase inhibitors
|
|
US20040266779A1
(en)
|
2001-09-27 |
2004-12-30 |
Anderson Kenneth C. |
Use of c-kit inhibitors for the treatment of myeloma
|
|
JP2005531488A
(ja)
|
2001-10-09 |
2005-10-20 |
ザ・ユニバーシティ・オブ・シンシナティ |
甲状腺癌を処置するためのｅｇｆ受容体阻害剤
|
|
US7521053B2
(en)
|
2001-10-11 |
2009-04-21 |
Amgen Inc. |
Angiopoietin-2 specific binding agents
|
|
US7658924B2
(en)
|
2001-10-11 |
2010-02-09 |
Amgen Inc. |
Angiopoietin-2 specific binding agents
|
|
EP1447405A4
(en)
|
2001-10-17 |
2005-01-12 |
Kirin Brewery |
CHINOLIN OR CHINAZOLINE DERIVATIVES THAT PREVENT THE AUTOPHOSPHORYLATION OF RECEPTORS FOR THE FIBROBLAST GROWTH FACTOR
|
|
ATE370123T1
(de)
|
2001-11-27 |
2007-09-15 |
Wyeth Corp |
3-cyanochinoline als inhibitoren von egf-r- und her2-kinasen
|
|
GB0201508D0
(en)
|
2002-01-23 |
2002-03-13 |
Novartis Ag |
Organic compounds
|
|
JP2003252737A
(ja)
|
2002-03-04 |
2003-09-10 |
Shin Etsu Chem Co Ltd |
口腔用組成物
|
|
CA2478169C
(en)
|
2002-03-04 |
2013-04-16 |
Imclone Systems Incorporated |
Human antibodies specific to kdr and uses thereof
|
|
EP1481678A4
(en)
|
2002-03-05 |
2009-12-30 |
Eisai R&D Man Co Ltd |
ANTITUMORAL AGENT CONTAINING A SULFONAMIDE-CONTAINING HETEROCYCLIC COMPOUND AND AN ANGIOGENESIS INHIBITOR
|
|
JP4619658B2
(ja)
*
|
2002-03-12 |
2011-01-26 |
富山化学工業株式会社 |
快い味の経口懸濁液および方法
|
|
AU2003226676A1
(en)
|
2002-03-20 |
2003-09-29 |
Dana-Farber Cancer Institute Inc. |
Methods and compositions for the identification, assessment, and therapy of small cell lung cancer
|
|
US6790852B2
(en)
|
2002-04-18 |
2004-09-14 |
Hoffmann-La Roche Inc. |
2-(2,6-dichlorophenyl)-diarylimidazoles
|
|
US7598258B2
(en)
|
2002-05-01 |
2009-10-06 |
Kirin Beer Kabushiki Kaisha |
Quinoline derivatives and quinazoline derivatives inhibiting autophosphorylation of macrophage colony stimulating factor receptor
|
|
PE20040522A1
(es)
|
2002-05-29 |
2004-09-28 |
Novartis Ag |
Derivados de diarilurea dependientes de la cinasa de proteina
|
|
UA77303C2
(en)
|
2002-06-14 |
2006-11-15 |
Pfizer |
Derivatives of thienopyridines substituted by benzocondensed heteroarylamide useful as therapeutic agents, pharmaceutical compositions and methods for their use
|
|
WO2004006862A2
(en)
|
2002-07-16 |
2004-01-22 |
Children's Medical Center Corporation |
A method for the modulation of angiogenesis
|
|
EP1523512B1
(en)
|
2002-07-22 |
2019-12-25 |
Aspen Aerogels Inc. |
Polyimide aerogels, carbon aerogels, and metal carbide aerogels and methods of making same
|
|
US7169936B2
(en)
|
2002-07-23 |
2007-01-30 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Indolinone derivatives substituted in the 6-position, their preparation and their use as medicaments
|
|
US7252976B2
(en)
|
2002-08-28 |
2007-08-07 |
Board Of Regents The University Of Texas System |
Quantitative RT-PCR to AC133 to diagnose cancer and monitor angiogenic activity in a cell sample
|
|
MXPA05001536A
(es)
|
2002-08-30 |
2005-04-19 |
Eisai Co Ltd |
Derivados aromaticos que contienen nitrogeno.
|
|
GB0223380D0
(en)
|
2002-10-09 |
2002-11-13 |
Astrazeneca Ab |
Combination therapy
|
|
BR0315169A
(pt)
|
2002-10-09 |
2005-08-23 |
Kosan Biosciences Inc |
Referência cruzada a pedidos de patente relacionados
|
|
JP4749660B2
(ja)
|
2002-10-16 |
2011-08-17 |
武田薬品工業株式会社 |
安定な固形製剤
|
|
AU2003273000A1
(en)
|
2002-10-16 |
2004-05-04 |
Takeda Pharmaceutical Company Limited |
Stable solid preparations
|
|
WO2004035543A1
(en)
|
2002-10-21 |
2004-04-29 |
Warner-Lambert Company Llc |
Tetrahydroquinoline derivatives as crth2 antagonists
|
|
AU2003280599A1
(en)
|
2002-10-29 |
2004-05-25 |
Kirin Beer Kabushiki Kaisha |
QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES INHIBITING AUTOPHOSPHORYLATION OF Flt3 AND MEDICINAL COMPOSITIONS CONTAINING THE SAME
|
|
DE10250711A1
(de)
|
2002-10-31 |
2004-05-19 |
Degussa Ag |
Pharmazeutische und kosmetische Zubereitungen
|
|
EP1558289A1
(en)
|
2002-11-06 |
2005-08-03 |
Cyclacel Limited |
Pharmaceutical composition comprising a cdk inhibitor and gemcitabine
|
|
GB0226434D0
(en)
|
2002-11-13 |
2002-12-18 |
Astrazeneca Ab |
Combination product
|
|
ITSV20020056A1
(it)
|
2002-11-14 |
2004-05-15 |
Alstom Transp Spa |
Dispositivo e metodo di verifica di motori software logici di comando di impianti ferroviari, in particolare di impianti di stazione
|
|
AR042042A1
(es)
|
2002-11-15 |
2005-06-08 |
Sugen Inc |
Administracion combinada de una indolinona con un agente quimioterapeutico para trastornos de proliferacion celular
|
|
ITMI20022447A1
(it)
|
2002-11-19 |
2004-05-20 |
Carlo Ghisalberti |
Uso di piridinoni nel trattamento della purpura capillare ed affezioni cutanee correlate.
|
|
KR20040053908A
(ko)
|
2002-12-16 |
2004-06-25 |
엘지전자 주식회사 |
열교환기의 응축수 배출구조
|
|
EP1615878B1
(en)
|
2003-01-14 |
2012-04-04 |
Cytokinetics, Inc. |
Compounds, compositions and methods of treatment for heart failure
|
|
JP3581361B1
(ja)
|
2003-02-17 |
2004-10-27 |
株式会社脳機能研究所 |
脳活動測定装置
|
|
EP1594470A4
(en)
|
2003-02-19 |
2007-10-17 |
Biovail Lab Int Srl |
QUICK ABSORPTION 5-HT SELECTIVE AGONIST FORMULATIONS
|
|
DK1603570T5
(da)
|
2003-02-26 |
2013-12-09 |
Sugen Inc |
Aminoheteroarylforbindelser som proteinkinaseinhibitorer
|
|
MXPA05009434A
(es)
|
2003-03-05 |
2005-11-23 |
Celgene Corp |
Compuestos de difeniletileno y usos de los mismos.
|
|
ATE508747T1
(de)
|
2003-03-10 |
2011-05-15 |
Eisai R&D Man Co Ltd |
C-kit kinase-hemmer
|
|
JPWO2004081047A1
(ja)
|
2003-03-14 |
2006-06-29 |
大正製薬株式会社 |
モノクローナル抗体及びこれを産生するハイブリドーマ
|
|
EP2385040A1
(en)
|
2003-03-14 |
2011-11-09 |
ONO Pharmaceutical Co., Ltd. |
Nitrogen-containing heterocyclic derivatives and drugs containing the same as the active ingredient
|
|
CA2521253A1
(en)
*
|
2003-04-02 |
2004-10-14 |
Pliva Istrazivanje I Razvoj D.O.O. |
Pharmaceutical compositions having reduced bitter taste
|
|
US20050014753A1
(en)
|
2003-04-04 |
2005-01-20 |
Irm Llc |
Novel compounds and compositions as protein kinase inhibitors
|
|
WO2004101526A1
(ja)
|
2003-04-22 |
2004-11-25 |
Eisai Co., Ltd. |
４－（３－クロロ－４－（シクロプロピルアミノカルボニル）アミノフェノキシ）－７－メトキシ－６－キノリンカルボキサミドの多形結晶及びその製造方法
|
|
KR100503949B1
(ko)
|
2003-04-28 |
2005-07-26 |
주식회사유한양행 |
염산 온단세트론의 쓴맛을 효과적으로 은폐한 경구용 구강속붕해정 조성물
|
|
EP1473043A1
(en)
|
2003-04-29 |
2004-11-03 |
Boehringer Ingelheim Pharma GmbH & Co.KG |
Pharmaceutical combination for the treatment of diseases involving cell proliferation, migration or apotosis of myeloma cells, or angiogenesis
|
|
US7107104B2
(en)
|
2003-05-30 |
2006-09-12 |
Medtronic, Inc. |
Implantable cortical neural lead and method
|
|
JP2005008534A
(ja)
|
2003-06-17 |
2005-01-13 |
Soc De Conseils De Recherches & D'applications Scientifiques (Scras) |
抗癌剤及び癌の治療方法
|
|
US20060167027A1
(en)
|
2003-07-10 |
2006-07-27 |
Wedge Stephen R |
Use of the quinazoline derivative zd6474 combined with platinum compounds and optionally ionising radiation in the treatment of diseases associated with angiogenesis and/or increased vascular permeability
|
|
CA2535242A1
(en)
|
2003-08-15 |
2005-02-24 |
Ab Science |
Use of c-kit inhibitors for treating type ii diabetes
|
|
EP1664032B1
(en)
|
2003-08-21 |
2008-11-05 |
OSI Pharmaceuticals, Inc. |
N-substituted pyrazolyl-amidyl-benzimidazolyl c-kit inhibitors
|
|
US7521448B2
(en)
|
2003-08-21 |
2009-04-21 |
Osi Pharmaceuticals, Inc. |
N-substituted benzimidazolyl c-Kit inhibitors
|
|
US7485658B2
(en)
|
2003-08-21 |
2009-02-03 |
Osi Pharmaceuticals, Inc. |
N-substituted pyrazolyl-amidyl-benzimidazolyl c-Kit inhibitors
|
|
US7312243B1
(en)
|
2003-08-29 |
2007-12-25 |
Jay Pravda |
Materials and methods for treatment of gastrointestinal disorders
|
|
MXPA06003163A
(es)
|
2003-09-23 |
2006-06-05 |
Novartis Ag |
Combinacion de un inhibidor de receptor de vegf con un agente quimioterapeutico.
|
|
WO2005030140A2
(en)
|
2003-09-26 |
2005-04-07 |
Exelixis, Inc. |
C-met modulators and methods of use
|
|
KR200340552Y1
(ko)
|
2003-10-08 |
2004-02-11 |
주식회사 엘지화학 |
창틀 내부에 블라인드 및 방범창 설치가 용이한 이중창틀
|
|
JP2005124034A
(ja)
|
2003-10-20 |
2005-05-12 |
Nippon Telegr & Teleph Corp <Ntt> |
発信者の特定及び発信者への呼び返しを可能とする回線設定方法
|
|
EP1683785B1
(en)
|
2003-11-11 |
2013-10-16 |
Eisai R&D Management Co., Ltd. |
Urea derivative and process for producing the same
|
|
BRPI0416935A
(pt)
|
2003-11-28 |
2007-01-16 |
Novartis Ag |
derivados de diaril ureia no tratamento de doenças dependentes de quìnase de proteìna
|
|
US6984403B2
(en)
*
|
2003-12-04 |
2006-01-10 |
Pfizer Inc. |
Azithromycin dosage forms with reduced side effects
|
|
KR20060129246A
(ko)
|
2003-12-05 |
2006-12-15 |
컴파운드 쎄라퓨틱스, 인크. |
타입 2 혈관 내피 성장 인자 수용체의 억제제
|
|
PL1698623T3
(pl)
|
2003-12-25 |
2015-08-31 |
Eisai R&D Man Co Ltd |
Postać krystaliczna soli 4-(3-chloro-4-(cyklopropyloaminokarbonylo)aminofenoksy)-7-metoksy-6-chinolinokarboksamidu lub jej solwatu i sposoby ich wytwarzania
|
|
CN1933839A
(zh)
|
2004-01-23 |
2007-03-21 |
安进公司 |
化合物和使用方法
|
|
EP1719763A4
(en)
|
2004-02-27 |
2008-01-09 |
Eisai R&D Man Co Ltd |
NEW PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (2)
|
|
KR20050091462A
(ko)
|
2004-03-12 |
2005-09-15 |
한국과학기술연구원 |
푸로피리미딘 화합물 및 이를 포함하는 ｄｄｒ2 티로신키나아제 활성 저해제
|
|
US7459562B2
(en)
|
2004-04-23 |
2008-12-02 |
Bristol-Myers Squibb Company |
Monocyclic heterocycles as kinase inhibitors
|
|
WO2005113507A1
(en)
|
2004-05-21 |
2005-12-01 |
Novartis Vaccines And Diagnostics Inc. |
Substituted quinoline derivatives as mitotic kinesin inhibitors
|
|
WO2005117887A1
(en)
|
2004-06-03 |
2005-12-15 |
F. Hoffmann-La Roche Ag |
Treatment with gemcitabine and an egfr-inhibitor
|
|
WO2006009765A2
(en)
*
|
2004-06-18 |
2006-01-26 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Methods for the identification and use of compounds suitable for the treatment of drug resistant cancer cells
|
|
US20050288290A1
(en)
|
2004-06-28 |
2005-12-29 |
Borzilleri Robert M |
Fused heterocyclic kinase inhibitors
|
|
US20050288521A1
(en)
|
2004-06-29 |
2005-12-29 |
Phytogen Life Sciences Inc. |
Semi-synthetic conversion of paclitaxel to docetaxel
|
|
EP1773826A4
(en)
|
2004-07-02 |
2009-06-03 |
Exelixis Inc |
MODULATORS OF C-MET AND THEIR METHOD OF USE
|
|
WO2006030941A1
(ja)
|
2004-09-13 |
2006-03-23 |
Eisai R & D Management Co., Ltd. |
スルホンアミド含有化合物の血管新生阻害物質との併用
|
|
US7306807B2
(en)
|
2004-09-13 |
2007-12-11 |
Wyeth |
Hemorrhagic feline calicivirus, calicivirus vaccine and method for preventing calicivirus infection or disease
|
|
US8772269B2
(en)
|
2004-09-13 |
2014-07-08 |
Eisai R&D Management Co., Ltd. |
Use of sulfonamide-including compounds in combination with angiogenesis inhibitors
|
|
WO2006030826A1
(ja)
*
|
2004-09-17 |
2006-03-23 |
Eisai R & D Management Co., Ltd. |
医薬組成物
|
|
CA2581375A1
(en)
|
2004-09-27 |
2006-04-06 |
Kosan Biosciences Incorporated |
Specific kinase inhibitors
|
|
CN101031285A
(zh)
|
2004-10-01 |
2007-09-05 |
卫材R&D管理有限公司 |
含有微粒的组合物及其制备方法
|
|
CN101495513B
(zh)
|
2004-10-19 |
2014-08-06 |
安姆根有限公司 |
促血管生成素-2特异性结合剂
|
|
CA2586420A1
(en)
|
2004-11-22 |
2007-04-12 |
King Pharmaceuticals Research & Development, Inc. |
Enhancing treatment of cancer and hif-1 mediated disoders with adenosine a3 receptor antagonists
|
|
EP1701722B1
(en)
|
2004-11-23 |
2009-10-14 |
Dong Wha Pharmaceutical Co., Ltd. |
N-hydroxy-4-{5-[4-(5-isopropyl-2-methyl-1,3-thiazol-4-yl)phenoxy¨]pentoxy}benzamidine 2 methansulfonic acid salt
|
|
JP2008521900A
(ja)
|
2004-11-30 |
2008-06-26 |
アムジエン・インコーポレーテツド |
キノリン及びキナゾリン類似体並びにがん治療のための医薬としてのその使用
|
|
CN100341504C
(zh)
|
2004-12-01 |
2007-10-10 |
鲁南制药集团股份有限公司 |
佐米曲普坦速释制剂
|
|
JP2008523072A
(ja)
|
2004-12-07 |
2008-07-03 |
ルーカス ファーマシューティカルズ， インコーポレイテッド |
タンパク質キナーゼの阻害剤
|
|
HRP20110859T1
(hr)
|
2004-12-21 |
2011-12-31 |
Medimmune Limited |
Protutijela usmjerena na angiopoietin-2 i njihova upotreba
|
|
US20060198885A1
(en)
|
2005-02-22 |
2006-09-07 |
Sun Pharmaceutical Industries Ltd. |
Oral pharmaceutical composition
|
|
JP2006230816A
(ja)
|
2005-02-25 |
2006-09-07 |
H & A Investment:Kk |
サンダル用ホルダー
|
|
US20080286282A1
(en)
|
2005-02-28 |
2008-11-20 |
Eisai R & D Management Co., Ltd. |
Novel Use of Sulfonamide Compound in Combination with Angiogenesis Inhibitor
|
|
US20090047278A1
(en)
|
2005-02-28 |
2009-02-19 |
Eisai R & D Management Co., Ltd. |
Novel Combinational Use of Sulfonamide Compound
|
|
US20090047365A1
(en)
|
2005-02-28 |
2009-02-19 |
Eisai R & D Management Co., Ltd. |
Novel Concomitant Use of Sulfonamide Compound with Anti-Cancer Agent
|
|
CN109485727A
(zh)
|
2005-05-09 |
2019-03-19 |
小野药品工业株式会社 |
程序性死亡-1(pd-1)的人单克隆抗体及使用抗pd-1抗体来治疗癌症的方法
|
|
MX2007014377A
(es)
|
2005-05-17 |
2008-02-06 |
Plexxikon Inc |
Inhibidores de proteina cinasa de derivados de pirrol (2,3-b) piridina.
|
|
PL1883397T3
(pl)
*
|
2005-05-17 |
2010-05-31 |
Actelion Pharmaceuticals Ltd |
Dyspergowalna tabletka bosertanu
|
|
WO2007002433A1
(en)
|
2005-06-22 |
2007-01-04 |
Plexxikon, Inc. |
Pyrrolo [2, 3-b] pyridine derivatives as protein kinase inhibitors
|
|
KR100951607B1
(ko)
|
2005-06-23 |
2010-04-09 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
4-(3-클로로-4-(시클로프로필아미노카르보닐)아미노페녹시)-7-메톡시-6-퀴놀린카르복사미드의 비정질 염 및 그 제조방법
|
|
US7550483B2
(en)
|
2005-06-23 |
2009-06-23 |
Eisai R&D Management Co., Ltd. |
Amorphous salt of 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide and process for preparing the same
|
|
CA2614358A1
(en)
|
2005-06-29 |
2007-01-04 |
Roselli, Patrizia |
Agonistic and antagonistic peptide mimetics of the vegf alpha-helix binding region for use in therapy
|
|
AU2006230974C1
(en)
|
2005-07-11 |
2012-02-02 |
Takeda Pharma A/S |
Benzimidazole formulation
|
|
US8101799B2
(en)
|
2005-07-21 |
2012-01-24 |
Ardea Biosciences |
Derivatives of N-(arylamino) sulfonamides as inhibitors of MEK
|
|
WO2007014335A2
(en)
|
2005-07-27 |
2007-02-01 |
The University Of Texas System |
Combinations comprising gemcitabine and tyrosine kinase inhibitors for the treatment of pancreatic cancer
|
|
JP5066446B2
(ja)
|
2005-08-01 |
2012-11-07 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
血管新生阻害物質の効果を予測する方法
|
|
JP4989476B2
(ja)
|
2005-08-02 |
2012-08-01 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
血管新生阻害物質の効果を検定する方法
|
|
WO2007023768A1
(ja)
|
2005-08-24 |
2007-03-01 |
Eisai R & D Management Co., Ltd. |
新規ピリジン誘導体およびピリミジン誘導体（３）
|
|
CN101277720A
(zh)
|
2005-09-01 |
2008-10-01 |
卫材R&D管理有限公司 |
崩解性被改善的药物组合物的制备方法
|
|
CN1308012C
(zh)
|
2005-11-02 |
2007-04-04 |
广州中医药大学第二附属医院 |
一种治疗脑出血的中药组合物及其制备方法
|
|
WO2007052849A1
(ja)
|
2005-11-07 |
2007-05-10 |
Eisai R & D Management Co., Ltd. |
血管新生阻害物質とc-kitキナーゼ阻害物質との併用
|
|
EP1964837A4
(en)
|
2005-11-22 |
2010-12-22 |
Eisai R&D Man Co Ltd |
Antitumor agent against multiple myeloma
|
|
US7825137B2
(en)
|
2005-12-05 |
2010-11-02 |
Pfizer Inc. |
Method of treating abnormal cell growth
|
|
AR059066A1
(es)
|
2006-01-27 |
2008-03-12 |
Amgen Inc |
Combinaciones del inhibidor de la angiopoyetina -2 (ang2) y el inhibidor del factor de crecimiento endotelial vascular (vegf)
|
|
ES2355306T3
(es)
|
2006-03-16 |
2011-03-24 |
Novartis Ag |
Forma de dosificación sólida que contiene un agente activo de sabor enmascarado.
|
|
KR100728926B1
(ko)
|
2006-03-20 |
2007-06-15 |
삼성전자주식회사 |
3축 힌지 구조를 갖는 휴대용 전자기기
|
|
CA2652442C
(en)
|
2006-05-18 |
2014-12-09 |
Eisai R & D Management Co., Ltd. |
Antitumor agent for thyroid cancer
|
|
ES2375284T3
(es)
|
2006-08-23 |
2012-02-28 |
Eisai R&D Management Co., Ltd. |
Sal de un derivado de fenoxipiridina, o cristal de la misma, y procedimiento de producción de la misma.
|
|
KR101472600B1
(ko)
|
2006-08-28 |
2014-12-15 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
미분화형 위암에 대한 항종양제
|
|
US7790885B2
(en)
|
2006-08-31 |
2010-09-07 |
Eisai R&D Management Co., Ltd. |
Process for preparing phenoxypyridine derivatives
|
|
CN101512017A
(zh)
|
2006-09-07 |
2009-08-19 |
阿斯利康(瑞典)有限公司 |
评价用靶向ret受体酪氨酸激酶的药物治疗的患者的方法
|
|
ES2538359T3
(es)
*
|
2006-10-12 |
2015-06-19 |
Ptc Therapeutics, Inc. |
Métodos para administrar un 1,2,4-oxadiazol activo por vía oral para terapia de supresión de mutación sin sentido
|
|
JP2009184925A
(ja)
*
|
2006-11-02 |
2009-08-20 |
Dai Ichi Seiyaku Co Ltd |
５−（１ｈ−１，２，３−トリアゾール−４−イル）−１ｈ−ピラゾール誘導体
|
|
CA2675358C
(en)
|
2007-01-19 |
2016-01-05 |
Ardea Biosciences, Inc. |
Inhibitors of mek
|
|
KR20090108086A
(ko)
|
2007-01-19 |
2009-10-14 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
췌장암 치료용 조성물
|
|
CN101600694A
(zh)
|
2007-01-29 |
2009-12-09 |
卫材R&D管理有限公司 |
未分化型胃癌治疗用组合物
|
|
CA2679602A1
(en)
|
2007-02-23 |
2008-08-28 |
Eisai R&D Management Co., Ltd. |
Pyridine or pyrimidine derivative having excellent cell growth inhibition effect and excellent anti-tumor effect on cell strain having amplification of hgfr gene
|
|
CN101641117B
(zh)
|
2007-03-05 |
2012-06-13 |
协和发酵麒麟株式会社 |
药物组合物
|
|
WO2008111441A1
(ja)
|
2007-03-05 |
2008-09-18 |
Kyowa Hakko Kirin Co., Ltd. |
医薬組成物
|
|
GB2448181B
(en)
|
2007-04-05 |
2011-11-09 |
Ford Global Tech Llc |
Vehicle headlight beam controls
|
|
US7807172B2
(en)
|
2007-06-13 |
2010-10-05 |
University Of Washington |
Methods and compositions for detecting thyroglobulin in a biological sample
|
|
PE20090368A1
(es)
|
2007-06-19 |
2009-04-28 |
Boehringer Ingelheim Int |
Anticuerpos anti-igf
|
|
CA2694646C
(en)
|
2007-07-30 |
2017-09-05 |
Ardea Biosciences, Inc. |
Combinations of mek inhibitors and raf kinase inhibitors and uses thereof
|
|
WO2009060945A1
(ja)
|
2007-11-09 |
2009-05-14 |
Eisai R & D Management Co., Ltd. |
血管新生阻害物質と抗腫瘍性白金錯体との併用
|
|
JP2009132660A
(ja)
|
2007-11-30 |
2009-06-18 |
Eisai R & D Management Co Ltd |
食道癌治療用組成物
|
|
JP5399926B2
(ja)
|
2008-01-29 |
2014-01-29 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
血管阻害物質とタキサンとの併用
|
|
GB2456907A
(en)
|
2008-01-30 |
2009-08-05 |
Astrazeneca Ab |
Method for determining subsequent VEGFR2 inhibitor therapy comprising measuring baseline VEGF level.
|
|
EP2259844A4
(en)
|
2008-03-05 |
2012-02-01 |
Vicus Therapeutics Llc |
COMPOSITIONS AND METHODS FOR MUCOSITIS AND ONCOLOGICAL THERAPIES
|
|
US8044240B2
(en)
|
2008-03-06 |
2011-10-25 |
Ardea Biosciences Inc. |
Polymorphic form of N-(S)-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide and uses thereof
|
|
EP2262837A4
(en)
|
2008-03-12 |
2011-04-06 |
Merck Sharp & Dohme |
PD-1 BINDING PROTEINS
|
|
BRPI0911297A2
(pt)
|
2008-04-14 |
2019-09-24 |
Ardea Biosciences Inc |
composição e métodos para preparo e uso das mesmas
|
|
JP2009263298A
(ja)
|
2008-04-28 |
2009-11-12 |
Ss Pharmaceut Co Ltd |
不快な味を隠ぺいした経口組成物
|
|
US8637554B2
(en)
|
2008-05-07 |
2014-01-28 |
The Trustees Of The University Of Pennsylvania |
Methods for treating thyroid cancer
|
|
JP5699075B2
(ja)
|
2008-05-14 |
2015-04-08 |
アムジエン・インコーポレーテツド |
癌の治療のためのｖｅｇｆ（ｒ）阻害剤および肝細胞増殖因子（ｃ−ｍｅｔ）阻害剤との組合せ
|
|
WO2009150255A2
(en)
|
2008-06-13 |
2009-12-17 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Markers for predicting response and survival in anti-egfr treated patients
|
|
KR20110028651A
(ko)
|
2008-07-11 |
2011-03-21 |
노파르티스 아게 |
(ａ) 포스포이노시타이드 3-키나제 억제제 및 (ｂ) ｒａｓ/ｒａｆ/ｍｅｋ 경로의 조절제의 조합물
|
|
CA2741087A1
(en)
|
2008-10-21 |
2010-04-29 |
Bayer Healthcare Llc |
Identification of signature genes associated with hepatocellular carcinoma
|
|
WO2010086964A1
(ja)
|
2009-01-28 |
2010-08-05 |
株式会社 静岡カフェイン工業所 |
がん治療のための併用療法
|
|
WO2011017583A1
(en)
|
2009-08-07 |
2011-02-10 |
The Wistar Institute |
Compositions containing jarid1b inhibitors and methods for treating cancer
|
|
US20120077842A1
(en)
*
|
2009-08-19 |
2012-03-29 |
Eisai R&D Management Co., Ltd. |
Quinoline derivative-containing pharmaceutical composition
|
|
WO2011022335A1
(en)
|
2009-08-21 |
2011-02-24 |
Mount Sinai School Of Medicine Of New York University |
Methods of using cd44 fusion proteins to treat cancer
|
|
EP2293071A1
(en)
|
2009-09-07 |
2011-03-09 |
Universität Zu Köln |
Biomarker for colorectal cancer
|
|
CA2802644C
(en)
|
2010-06-25 |
2017-02-21 |
Eisai R & D Management Co., Ltd. |
Antitumor agent using compounds having kinase inhibitory effect in combination
|
|
EP2594566A4
(en)
|
2010-07-16 |
2014-10-01 |
Kyowa Hakko Kirin Co Ltd |
AROMATIC HETEROCYCLIC NITROGEN CYCLE DERIVATIVE
|
|
EP2596363B1
(en)
|
2010-07-19 |
2017-01-18 |
F. Hoffmann-La Roche AG |
Blood plasma biomarkers for bevacizumab combination therapies for treatment of breast cancer
|
|
CN103140761B
(zh)
|
2010-07-19 |
2015-11-25 |
霍夫曼-拉罗奇有限公司 |
贝伐单抗组合疗法用于治疗胰腺癌的血浆生物标志物
|
|
JP2013538338A
(ja)
|
2010-07-19 |
2013-10-10 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
抗癌治療への応答可能性の増大した患者を同定する方法
|
|
SG10201505593VA
(en)
|
2010-07-19 |
2015-09-29 |
Hoffmann La Roche |
Method to identify a patient with an increased likelihood of responding to an anti-cancer therapy
|
|
WO2012019300A1
(en)
|
2010-08-10 |
2012-02-16 |
Siu K W Michael |
Endometrial cancer biomarkers and methods of identifying and using same
|
|
WO2012029913A1
(ja)
|
2010-09-01 |
2012-03-08 |
興和株式会社 |
経口剤
|
|
US20120077837A1
(en)
|
2010-09-24 |
2012-03-29 |
Eisai R&D Management Co., Ltd. |
Anti-tumor agent
|
|
KR20120077842A
(ko)
|
2010-12-31 |
2012-07-10 |
서병윤 |
천장 크레인용 유압식 장착수단의 작동유 냉각 장치
|
|
MY181439A
(en)
|
2011-02-28 |
2020-12-22 |
Sunshine Lake Pharma Co Ltd |
Substituted quinoline compounds and methods of use
|
|
CA2864394C
(en)
|
2011-03-02 |
2021-10-19 |
Jack Roth |
A method of predicting a response to a tusc2 therapy
|
|
US9107887B2
(en)
|
2011-03-10 |
2015-08-18 |
Provectus Pharmaceuticals, Inc. |
Combination of local and systemic immunomodulative therapies for enhanced treatment of cancer
|
|
CA2828946C
(en)
|
2011-04-18 |
2016-06-21 |
Eisai R&D Management Co., Ltd. |
Therapeutic agent for tumor
|
|
WO2012154935A1
(en)
|
2011-05-12 |
2012-11-15 |
Eisai R&D Management Co., Ltd. |
Biomarkers that are predictive of responsiveness or non-responsiveness to treatment with lenvatinib or a pharmaceutically acceptable salt thereof
|
|
EP2711433B1
(en)
|
2011-05-17 |
2017-02-15 |
Eisai R&D Management Co., Ltd. |
Method for predicting effectiveness of angiogenesis inhibitor
|
|
US9945862B2
(en)
|
2011-06-03 |
2018-04-17 |
Eisai R&D Management Co., Ltd. |
Biomarkers for predicting and assessing responsiveness of thyroid and kidney cancer subjects to lenvatinib compounds
|
|
AR087405A1
(es)
|
2011-08-01 |
2014-03-19 |
Genentech Inc |
Metodos para tratar el cancer por el uso de antagonistas de union al eje pd-1 e inhibidores de mek
|
|
US20130071403A1
(en)
|
2011-09-20 |
2013-03-21 |
Vical Incorporated |
Synergistic anti-tumor efficacy using alloantigen combination immunotherapy
|
|
US10092651B2
(en)
|
2012-02-28 |
2018-10-09 |
Seoul Pharma Co., Ltd. |
High-content fast dissolving film with masking of bitter taste comprising sildenafil as active ingredient
|
|
AR090263A1
(es)
|
2012-03-08 |
2014-10-29 |
Hoffmann La Roche |
Terapia combinada de anticuerpos contra el csf-1r humano y las utilizaciones de la misma
|
|
US9856320B2
(en)
|
2012-05-15 |
2018-01-02 |
Bristol-Myers Squibb Company |
Cancer immunotherapy by disrupting PD-1/PD-L1 signaling
|
|
JP2015517511A
(ja)
|
2012-05-16 |
2015-06-22 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Ｃｄ３７抗体とｉｃｅ（イフォスファミド、カルボプラチン、エトポシド）の併用
|
|
AU2013327116C1
(en)
|
2012-10-02 |
2018-08-30 |
Bristol-Myers Squibb Company |
Combination of anti-KIR antibodies and anti-PD-1 antibodies to treat cancer
|
|
RU2689977C2
(ru)
|
2012-12-04 |
2019-05-30 |
Эйсай Ар Энд Ди Менеджмент Ко., Лтд. |
Применение эрибулина для лечения рака молочной железы
|
|
EP3939614A1
(en)
|
2013-01-18 |
2022-01-19 |
Foundation Medicine, Inc. |
Methods of treating cholangiocarcinoma
|
|
SG11201505252VA
(en)
|
2013-02-28 |
2015-08-28 |
Eisai R&D Man Co Ltd |
Tetrahydroimidazo[1,5-d][1,4]oxazepine derivative
|
|
SG11201509278XA
(en)
|
2013-05-14 |
2015-12-30 |
Eisai R&D Man Co Ltd |
Biomarkers for predicting and assessing responsiveness of endometrial cancer subjects to lenvatinib compounds
|
|
KR102265952B1
(ko)
|
2013-06-26 |
2021-06-16 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
암 치료 병용요법으로서 에리불린 및 렌바티닙의 용도
|
|
US9174998B2
(en)
|
2013-12-25 |
2015-11-03 |
Eisai R&D Management Co., Ltd. |
(6S,9aS)-N-benzyl-6-[(4-hydroxyphenyl)methyl]-4,7-dioxo-8-({6-[3-(piperazin-1-yl)azetidin-1-yl]pyridin-2-yl}methyl)-2-(prop-2-en-1-yl)-octahydro-1H-pyrazino[2,1-c][1,2,4]triazine-1-carboxamide compound
|
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
|
CA2938566A1
(en)
|
2014-02-04 |
2015-08-13 |
Incyte Corporation |
Combination of a pd-1 antagonist and an ido1 inhibitor for treating cancer
|
|
IL302218B2
(en)
|
2014-08-28 |
2024-10-01 |
Eisai R&D Man Co Ltd |
Methods for manufacturing high-purity lenvatinib and its derivatives
|
|
AU2015384801B2
(en)
|
2015-03-04 |
2022-01-06 |
Eisai R&D Management Co., Ltd. |
Combination of a PD-1 antagonist and a VEGFR/FGFR/RET tyrosine kinase inhibitor for treating cancer
|
|
EP3311841B1
(en)
|
2015-06-16 |
2021-07-28 |
PRISM BioLab Co., Ltd. |
Anticancer agent
|
|
CN107614504B
(zh)
|
2015-06-23 |
2019-12-24 |
卫材R&D管理有限公司 |
甲酰胺化合物的晶体
|
|
US20200375975A1
(en)
|
2016-04-15 |
2020-12-03 |
Eisai R&D Management Co., Ltd. |
Treatment of Renal Cell Carcinoma with Lenvatinib and Everolimus
|