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DK3166927T3 - Fremgangsmåde til fremstilling af 4-alkoxy-3-hydroxy-picolinsyre - Google Patents

Fremgangsmåde til fremstilling af 4-alkoxy-3-hydroxy-picolinsyre Download PDF

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Publication number
DK3166927T3
DK3166927T3 DK15818435.8T DK15818435T DK3166927T3 DK 3166927 T3 DK3166927 T3 DK 3166927T3 DK 15818435 T DK15818435 T DK 15818435T DK 3166927 T3 DK3166927 T3 DK 3166927T3
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DK
Denmark
Prior art keywords
alcohy
hydroxy
preparing
picolic acid
picolic
Prior art date
Application number
DK15818435.8T
Other languages
English (en)
Inventor
James M Renga
Yuanming Zhu
Gregory T Whiteker
Nakyen Choy
Original Assignee
Dow Agrosciences Llc
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Publication of DK3166927T3 publication Critical patent/DK3166927T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84Nitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • C07D213/803Processes of preparation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK15818435.8T 2014-07-08 2015-07-08 Fremgangsmåde til fremstilling af 4-alkoxy-3-hydroxy-picolinsyre DK3166927T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201462021877P 2014-07-08 2014-07-08
US201462021876P 2014-07-08 2014-07-08
US201462021881P 2014-07-08 2014-07-08
PCT/US2015/039569 WO2016007638A1 (en) 2014-07-08 2015-07-08 Process for the preparation of 4-alkoxy-3-hydroxypicolinic acids

Publications (1)

Publication Number Publication Date
DK3166927T3 true DK3166927T3 (da) 2020-07-27

Family

ID=55064837

Family Applications (3)

Application Number Title Priority Date Filing Date
DK15819075.1T DK3166612T3 (da) 2014-07-08 2015-07-08 Fremgangsmåde til fremstilling af 4-alkoxy-3-hydroxy-picolinsyre
DK15818752.6T DK3166611T3 (da) 2014-07-08 2015-07-08 Fremgangsmåde til fremstilling af 4-alkoxy-3-hydroxypicolinsyrer
DK15818435.8T DK3166927T3 (da) 2014-07-08 2015-07-08 Fremgangsmåde til fremstilling af 4-alkoxy-3-hydroxy-picolinsyre

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK15819075.1T DK3166612T3 (da) 2014-07-08 2015-07-08 Fremgangsmåde til fremstilling af 4-alkoxy-3-hydroxy-picolinsyre
DK15818752.6T DK3166611T3 (da) 2014-07-08 2015-07-08 Fremgangsmåde til fremstilling af 4-alkoxy-3-hydroxypicolinsyrer

Country Status (16)

Country Link
US (4) US9522887B2 (da)
EP (3) EP3166927B1 (da)
JP (4) JP6625115B2 (da)
KR (3) KR102441177B1 (da)
CN (3) CN106573005B (da)
BR (3) BR112017000061B8 (da)
CA (3) CA2954167C (da)
CO (3) CO2017000049A2 (da)
DK (3) DK3166612T3 (da)
ES (3) ES2836201T3 (da)
IL (3) IL249891B (da)
MX (3) MX373312B (da)
PL (3) PL3166612T3 (da)
TW (5) TWI684587B (da)
WO (3) WO2016007638A1 (da)
ZA (1) ZA201700254B (da)

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CN108495845A (zh) * 2016-01-22 2018-09-04 美国陶氏益农公司 制备4-烷氧基-3-乙酰氧基吡啶甲酸的方法
EP3405034B1 (en) * 2016-01-22 2021-05-12 Dow Agrosciences LLC Process for the preparation of 4-alkoxy-3-hydroxypicolinic acids
TW201733985A (zh) * 2016-02-29 2017-10-01 陶氏農業科學公司 用於製備4-烷氧基-3-羥基吡啶甲酸之方法
TWI733749B (zh) * 2017-01-25 2021-07-21 美商陶氏農業科學公司 用於製備4-烷氧基-3-羥基吡啶甲酸之方法
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UY40356A (es) 2022-07-18 2024-01-31 Pi Ind Ltd Un proceso para la síntesis de ácidos 4-alcoxi-3-hidroxipicolínicos e intermedios de los mismos.

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TWI684587B (zh) * 2014-07-08 2020-02-11 美商陶氏農業科學公司 用於製備4-烷氧基-3-羥基吡啶甲酸之方法(二)

Also Published As

Publication number Publication date
EP3166927B1 (en) 2020-04-22
TWI689498B (zh) 2020-04-01
KR20170023942A (ko) 2017-03-06
EP3166611A4 (en) 2018-02-21
ES2836201T3 (es) 2021-06-24
KR20170029506A (ko) 2017-03-15
MX387774B (es) 2025-03-18
IL249911A0 (en) 2017-03-30
CA2954167C (en) 2023-01-03
JP2017523962A (ja) 2017-08-24
ES2807622T3 (es) 2021-02-23
TWI682923B (zh) 2020-01-21
CA2954284C (en) 2022-12-13
TW201625541A (zh) 2016-07-16
US20160009649A1 (en) 2016-01-14
IL249911B (en) 2020-02-27
TW201625542A (zh) 2016-07-16
US9522887B2 (en) 2016-12-20
CN106659724B (zh) 2020-04-28
EP3166927A1 (en) 2017-05-17
CA2954284A1 (en) 2016-01-14
BR112017000061B8 (pt) 2023-05-16
MX2016017106A (es) 2017-05-10
IL249893B (en) 2020-02-27
TWI684587B (zh) 2020-02-11
IL249891A0 (en) 2017-03-30
TW202003481A (zh) 2020-01-16
TW201625571A (zh) 2016-07-16
JP2017523960A (ja) 2017-08-24
US9481651B2 (en) 2016-11-01
MX369327B (es) 2019-11-05
BR112017000135B1 (pt) 2022-08-09
CN106573005B (zh) 2020-05-29
WO2016007637A1 (en) 2016-01-14
DK3166612T3 (da) 2019-09-23
BR112016031007B1 (pt) 2021-04-27
CN106573005A (zh) 2017-04-19
US9475771B2 (en) 2016-10-25
CO2017000446A2 (es) 2017-05-10
CN106660957A (zh) 2017-05-10
CN106659724A (zh) 2017-05-10
PL3166611T3 (pl) 2021-04-06
CA2954167A1 (en) 2016-01-14
ES2738401T3 (es) 2020-01-22
CO2017000049A2 (es) 2017-05-10
DK3166611T3 (da) 2020-12-07
JP2017521429A (ja) 2017-08-03
PL3166612T3 (pl) 2019-12-31
US20160009650A1 (en) 2016-01-14
BR112017000061B1 (pt) 2022-10-25
EP3166612B1 (en) 2019-06-12
EP3166611B1 (en) 2020-09-16
BR112016031007B8 (pt) 2022-08-23
KR102450085B1 (ko) 2022-10-04
JP6513178B2 (ja) 2019-05-15
ZA201700254B (en) 2018-12-19
JP6625115B2 (ja) 2019-12-25
EP3166611A1 (en) 2017-05-17
CN106660957B (zh) 2019-11-29
EP3166612A4 (en) 2017-12-20
EP3166927A4 (en) 2017-12-20
WO2016007638A1 (en) 2016-01-14
KR102436286B1 (ko) 2022-08-26
CA2954276C (en) 2022-12-13
BR112017000135A2 (pt) 2017-11-07
KR102441177B1 (ko) 2022-09-07
TWI720647B (zh) 2021-03-01
BR112017000135B8 (pt) 2023-05-16
US9718783B2 (en) 2017-08-01
IL249891B (en) 2020-07-30
WO2016007634A1 (en) 2016-01-14
EP3166612A1 (en) 2017-05-17
JP2020073575A (ja) 2020-05-14
MX373312B (es) 2020-05-20
IL249893A0 (en) 2017-03-30
KR20170029501A (ko) 2017-03-15
BR112017000061A2 (pt) 2017-11-07
TW201943703A (zh) 2019-11-16
MX2016017120A (es) 2017-05-10
CA2954276A1 (en) 2016-01-14
JP6688278B2 (ja) 2020-04-28
US20160009676A1 (en) 2016-01-14
MX2016017127A (es) 2017-05-10
CO2017000430A2 (es) 2017-04-28
PL3166927T3 (pl) 2020-10-19
US20170044105A1 (en) 2017-02-16

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