DK3177634T3 - Modificerede nukleotidlinkere - Google Patents
Modificerede nukleotidlinkere Download PDFInfo
- Publication number
- DK3177634T3 DK3177634T3 DK15750100.8T DK15750100T DK3177634T3 DK 3177634 T3 DK3177634 T3 DK 3177634T3 DK 15750100 T DK15750100 T DK 15750100T DK 3177634 T3 DK3177634 T3 DK 3177634T3
- Authority
- DK
- Denmark
- Prior art keywords
- modified nucleotide
- nucleotide linkers
- linkers
- modified
- nucleotide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/14—Pyrrolo-pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1414098.2A GB201414098D0 (en) | 2014-08-08 | 2014-08-08 | Modified nucleotide linkers |
| PCT/GB2015/052282 WO2016020691A1 (en) | 2014-08-08 | 2015-08-06 | Modified nucleotide linkers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3177634T3 true DK3177634T3 (da) | 2020-03-02 |
Family
ID=51629525
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK19178987.4T DK3564252T3 (da) | 2014-08-08 | 2015-08-06 | Modificerede nukleotidlinkere |
| DK15750100.8T DK3177634T3 (da) | 2014-08-08 | 2015-08-06 | Modificerede nukleotidlinkere |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK19178987.4T DK3564252T3 (da) | 2014-08-08 | 2015-08-06 | Modificerede nukleotidlinkere |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US10190157B2 (da) |
| EP (2) | EP3564252B1 (da) |
| JP (3) | JP6563482B2 (da) |
| KR (2) | KR102287718B1 (da) |
| CN (2) | CN111704643A (da) |
| AU (2) | AU2015298469B2 (da) |
| BR (2) | BR112017002251B1 (da) |
| CA (1) | CA2957382C (da) |
| DK (2) | DK3564252T3 (da) |
| ES (2) | ES2773438T3 (da) |
| GB (1) | GB201414098D0 (da) |
| IL (1) | IL250498B (da) |
| MX (2) | MX385213B (da) |
| MY (1) | MY195167A (da) |
| NZ (2) | NZ728810A (da) |
| RU (1) | RU2699993C2 (da) |
| SG (3) | SG10201900948PA (da) |
| WO (1) | WO2016020691A1 (da) |
| ZA (1) | ZA201700838B (da) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| WO2017058953A1 (en) | 2015-09-28 | 2017-04-06 | The Trustees Of Columbia University In The City Of New York | Design and synthesis of novel disulfide linker based nucleotides as reversible terminators for dna sequencing by synthesis |
| CN116656795A (zh) | 2016-05-23 | 2023-08-29 | 纽约哥伦比亚大学董事会 | 核苷酸衍生物及其使用方法 |
| KR102586847B1 (ko) * | 2016-12-22 | 2023-10-10 | 일루미나, 인코포레이티드 | 시퀀싱 프라이머 및 비-시퀀싱 존재물을 포함하는 어레이 |
| EP3596099B1 (en) | 2017-03-06 | 2024-07-24 | Singular Genomics Systems, Inc. | Nucleic acid sequencing-by-synthesis (sbs) methods that combine sbs cycle steps |
| US12018325B2 (en) | 2017-03-28 | 2024-06-25 | The Trustees Of Columbia University In The City Of New York | 3′-O-modified nucleotide analogues with different cleavable linkers for attaching fluorescent labels to the base for DNA sequencing by synthesis |
| CN110650968B (zh) * | 2017-10-11 | 2022-07-05 | 深圳华大智造科技股份有限公司 | 修饰的核苷或核苷酸 |
| US12215124B2 (en) | 2018-02-21 | 2025-02-04 | Singular Genomics Systems, Inc. | Fluorinated nucleotides and uses thereof |
| CN112218640A (zh) | 2018-03-15 | 2021-01-12 | 哥伦比亚大学董事会 | 核苷酸类似物及其在核酸测序和分析中的用途 |
| US12145960B2 (en) | 2018-10-25 | 2024-11-19 | Singular Genomics Systems, Inc. | Nucleotide analogues |
| ES2973302T3 (es) | 2018-12-14 | 2024-06-19 | Illumina Cambridge Ltd | Disminución del ajuste de fase con nucleótidos sin marcar durante la secuenciación |
| US11293061B2 (en) | 2018-12-26 | 2022-04-05 | Illumina Cambridge Limited | Sequencing methods using nucleotides with 3′ AOM blocking group |
| EP3908286A4 (en) | 2019-01-08 | 2022-10-12 | Singular Genomics Systems, Inc. | NUCLEOTIDE CLEAVABLE LINKERS AND THEIR USES |
| JP7587424B2 (ja) | 2019-03-01 | 2024-11-20 | イルミナ ケンブリッジ リミテッド | 環外アミン置換クマリン化合物およびそれらの蛍光標識としての使用 |
| NL2023327B1 (en) | 2019-03-01 | 2020-09-17 | Illumina Inc | Multiplexed fluorescent detection of analytes |
| WO2020178231A1 (en) | 2019-03-01 | 2020-09-10 | Illumina, Inc. | Multiplexed fluorescent detection of analytes |
| US12110546B2 (en) * | 2019-03-01 | 2024-10-08 | Illumina Cambridge Limited | Tertiary amine substituted coumarin compounds and uses as fluorescent labels |
| US11421271B2 (en) | 2019-03-28 | 2022-08-23 | Illumina Cambridge Limited | Methods and compositions for nucleic acid sequencing using photoswitchable labels |
| EP4065646A1 (en) | 2019-11-27 | 2022-10-05 | Illumina Cambridge Limited | Cyclooctatetraene containing dyes and compositions |
| JP7287299B2 (ja) | 2020-01-31 | 2023-06-06 | トヨタ自動車株式会社 | 車両および車両制御インターフェース |
| JP2023531009A (ja) | 2020-06-22 | 2023-07-20 | イルミナ ケンブリッジ リミテッド | ３’アセタールブロッキング基を有するヌクレオシド及びヌクレオチド |
| US11981964B2 (en) | 2020-07-28 | 2024-05-14 | Illumina Cambridge Limited | Substituted coumarin dyes and uses as fluorescent labels |
| US20220195517A1 (en) | 2020-12-17 | 2022-06-23 | Illumina Cambridge Limited | Long stokes shift chromenoquinoline dyes and uses in sequencing applications |
| US20220195196A1 (en) | 2020-12-17 | 2022-06-23 | Illumina Cambridge Limited | Alkylpyridinium coumarin dyes and uses in sequencing applications |
| US20220195516A1 (en) | 2020-12-17 | 2022-06-23 | Illumina Cambridge Limited | Methods, systems and compositions for nucleic acid sequencing |
| US20220195518A1 (en) | 2020-12-22 | 2022-06-23 | Illumina Cambridge Limited | Methods and compositions for nucleic acid sequencing |
| EP4334327A1 (en) | 2021-05-05 | 2024-03-13 | Illumina Cambridge Limited | Fluorescent dyes containing bis-boron fused heterocycles and uses in sequencing |
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| JP2024520279A (ja) * | 2021-05-26 | 2024-05-24 | イルミナ インコーポレイテッド | ３’－ブロック化ヌクレオチドの精製及び重合 |
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