DK1928840T3 - 1H-pyrazol-4-carboxamider, deres fremstilling og deres anvendelse som 11-beta-hydroxysteroid-dehydrogenaseinhibitorer - Google Patents
1H-pyrazol-4-carboxamider, deres fremstilling og deres anvendelse som 11-beta-hydroxysteroid-dehydrogenaseinhibitorerInfo
- Publication number
- DK1928840T3 DK1928840T3 DK06725326.0T DK06725326T DK1928840T3 DK 1928840 T3 DK1928840 T3 DK 1928840T3 DK 06725326 T DK06725326 T DK 06725326T DK 1928840 T3 DK1928840 T3 DK 1928840T3
- Authority
- DK
- Denmark
- Prior art keywords
- carboxamides
- pyrazole
- beta
- preparation
- hydroxysteroid dehydrogenase
- Prior art date
Links
- 102000004277 11-beta-hydroxysteroid dehydrogenases Human genes 0.000 title 1
- 108090000874 11-beta-hydroxysteroid dehydrogenases Proteins 0.000 title 1
- ZVXKYWHJBYIYNI-UHFFFAOYSA-N 1h-pyrazole-4-carboxamide Chemical class NC(=O)C=1C=NNC=1 ZVXKYWHJBYIYNI-UHFFFAOYSA-N 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Child & Adolescent Psychology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66836705P | 2005-04-05 | 2005-04-05 | |
| PCT/EP2006/061057 WO2006106052A1 (en) | 2005-04-05 | 2006-03-27 | Pyrazoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1928840T3 true DK1928840T3 (da) | 2011-09-12 |
Family
ID=36514279
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK06725326.0T DK1928840T3 (da) | 2005-04-05 | 2006-03-27 | 1H-pyrazol-4-carboxamider, deres fremstilling og deres anvendelse som 11-beta-hydroxysteroid-dehydrogenaseinhibitorer |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US7345058B2 (da) |
| EP (1) | EP1928840B1 (da) |
| JP (1) | JP4880671B2 (da) |
| KR (1) | KR100931411B1 (da) |
| CN (1) | CN101155783B (da) |
| AR (1) | AR053203A1 (da) |
| AT (1) | ATE519744T1 (da) |
| AU (1) | AU2006232660B2 (da) |
| BR (1) | BRPI0610459A2 (da) |
| CA (1) | CA2602781C (da) |
| DK (1) | DK1928840T3 (da) |
| ES (1) | ES2369389T3 (da) |
| IL (1) | IL186118A0 (da) |
| MX (1) | MX2007012212A (da) |
| NO (1) | NO20074872L (da) |
| PL (1) | PL1928840T3 (da) |
| PT (1) | PT1928840E (da) |
| RU (1) | RU2381217C2 (da) |
| TW (1) | TWI309645B (da) |
| WO (1) | WO2006106052A1 (da) |
| ZA (1) | ZA200708419B (da) |
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| CN101312951A (zh) * | 2005-11-21 | 2008-11-26 | 盐野义制药株式会社 | 具有Ⅰ型11β羟基类固醇脱氢酶抑制活性的杂环化合物 |
| RS54216B1 (sr) * | 2006-03-22 | 2015-12-31 | F. Hoffmann-La Roche Ag. | Pirazoli kao 11-beta-hsd-1 |
| PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
| EP2051977A2 (en) * | 2006-07-20 | 2009-04-29 | Amgen Inc. | SUBSTITUTED AZOLE AROMATIC HETEROCYCLES AS INHIBITORS OF LLbeta-HSD-1 |
| TW200827346A (en) * | 2006-11-03 | 2008-07-01 | Astrazeneca Ab | Chemical compounds |
| TW200836719A (en) | 2007-02-12 | 2008-09-16 | Astrazeneca Ab | Chemical compounds |
| JP5319518B2 (ja) * | 2007-04-02 | 2013-10-16 | Ｍｓｄ株式会社 | インドールジオン誘導体 |
| JP4671369B2 (ja) * | 2007-05-18 | 2011-04-13 | 塩野義製薬株式会社 | Ｉ型１１βヒドロキシステロイド脱水素酵素阻害活性を有する含窒素複素環誘導体 |
| WO2009010416A2 (en) | 2007-07-17 | 2009-01-22 | F. Hoffmann-La Roche Ag | Inhibitors of 11b-hydroxysteroid dehydrogenase |
| FR2924931B1 (fr) * | 2007-12-12 | 2010-01-15 | Oreal | Utilisations de derives 1-°(1h-pyrazol-4-y!heterocycliques pour stimuler ou induire la pousse des fibres keratiniques et/ou freiner leur chute ; nouveaux composes ; compositions les contenant. |
| CN101969946A (zh) * | 2008-02-04 | 2011-02-09 | 阿斯利康(瑞典)有限公司 | 4-[4-(2-金刚烷基氨基甲酰基)-5-叔丁基-吡唑-1-基]苯甲酸的新晶型 |
| JP2012516327A (ja) * | 2009-01-30 | 2012-07-19 | アストラゼネカ アクチボラグ | カルボキシ含有ピラゾールアミド化合物を製造するための新規な方法 |
| UY33001A (es) * | 2009-11-06 | 2011-05-31 | Boehringer Ingelheim Int | Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina |
| MX2014015345A (es) | 2012-06-20 | 2015-03-05 | Hoffmann La Roche | Inhibidores piranopiridona de tanquirasa. |
| RU2674983C1 (ru) * | 2013-11-25 | 2018-12-14 | Корсепт Терапеутикс, Инк. | Октагидро конденсированные азадекалиновые модуляторы глюкокортикоидного рецептора |
| US9273254B2 (en) * | 2013-12-20 | 2016-03-01 | Ecolab Usa Inc. | Amino acetals and ketals as hydrogen sulfide and mercaptan scavengers |
| CN103772282B (zh) * | 2014-02-26 | 2015-09-23 | 上海毕得医药科技有限公司 | 一种3-叔丁基-1h-吡唑-4-甲醛的制备方法 |
| US11234971B2 (en) | 2018-12-19 | 2022-02-01 | Corcept Therapeutics Incorporated | Methods of treating cancer comprising administration of a glucocorticoid receptor modulator and a cancer chemotherapy agent |
| WO2020132046A1 (en) | 2018-12-19 | 2020-06-25 | Corcept Therapeutics Incorporated | Methods of treating cancer comprising administration of a glucocorticoid receptor modulator and a cancer chemotherapy agent |
| EP3927345A4 (en) | 2019-02-22 | 2022-12-21 | Corcept Therapeutics Incorporated | Therapeutic uses of relacorilant, a heteroaryl-ketone fused azadecalin glucocorticoid receptor modulator |
| EP4072556A4 (en) | 2019-12-11 | 2024-01-03 | Corcept Therapeutics Incorporated | METHODS OF TREATING ANTIPSYCHOTIC DRUG-INDUCED WEIGHT GAIN WITH MIRICORILANT |
| AU2021282256A1 (en) * | 2020-05-27 | 2022-12-15 | Corcept Therapeutics Incorporated | Concomitant administration of glucocorticoid receptor modulator relacorilant and CYP2C8 substrates |
| CN114560811B (zh) * | 2022-03-11 | 2023-09-01 | 上海立森印迹医药技术有限公司 | 1,3,5-三取代-吡唑-4羧酸衍生物及其制备方法和应用 |
| CN120202004A (zh) | 2022-10-28 | 2025-06-24 | 科赛普特治疗学股份有限公司 | 使用达祖可兰治疗肌萎缩侧索硬化症 |
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| NO760996L (da) * | 1975-03-25 | 1976-09-28 | Byk Gulden Lomberg Chem Fab | |
| US4620865A (en) | 1983-11-07 | 1986-11-04 | Eli Lilly And Company | Herbicidal and algicidal 1,5-disubstituted-1H-pyrazole-4-carboxamides |
| US4792565A (en) * | 1986-04-24 | 1988-12-20 | Mitsui Toatsu Chemicals, Inc. | Pyrazolecarbonylamine derivatives and agricultural and horticultural fungicides containing said compounds |
| JPH0768220B2 (ja) * | 1986-04-24 | 1995-07-26 | 三井東圧化学株式会社 | 新規ピラゾ−ル誘導体、その製造法およびそれらを含有する農園芸用殺菌剤 |
| IL91418A (en) * | 1988-09-01 | 1997-11-20 | Rhone Poulenc Agrochimie | (hetero) cyclic amide derivatives, process for their preparation and fungicidal compositions containing them |
| MY138097A (en) | 2000-03-22 | 2009-04-30 | Du Pont | Insecticidal anthranilamides |
| SE0001899D0 (sv) | 2000-05-22 | 2000-05-22 | Pharmacia & Upjohn Ab | New compounds |
| JP2002003410A (ja) | 2000-06-27 | 2002-01-09 | Fuji Photo Film Co Ltd | 芳香族ハロゲン化物の製造方法。 |
| CA2430061A1 (en) | 2000-11-28 | 2002-06-06 | Pfizer Products Inc. | Preparation of sodium-hydrogen exchanger type-1 inhibitors |
| GB0107383D0 (en) | 2001-03-23 | 2001-05-16 | Univ Edinburgh | Lipid profile modulation |
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| PL370447A1 (en) | 2001-11-22 | 2005-05-30 | Biovitrum Ab | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 |
| MXPA04004837A (es) | 2001-11-22 | 2004-08-02 | Biovitrum Ab | Inhibidores de 11-??-hidroxiesteroide deshidrogenasa de tipo 1. |
| WO2003051845A1 (en) | 2001-12-19 | 2003-06-26 | Pfizer Products Inc. | Methods for preparing sodium-hydrogen exchanger type-1 inhibitors |
| AU2002361861A1 (en) | 2001-12-21 | 2003-07-30 | Rhode Island Hospital | SELECTIVE 11Beta-HSD INHIBITORS AND METHODS FOR USE THEREOF |
| DE60317631T2 (de) | 2002-02-01 | 2008-09-25 | Merck & Co., Inc. | 11-beta-hydroxysteroid-dehydrogenase-1-hemmer zur behandlung von diabetes, adipositas und dyslipidämie |
| EP1482794A1 (en) | 2002-03-06 | 2004-12-08 | Merck & Co., Inc. | Method of treatment or prevention of obesity |
| AR040241A1 (es) | 2002-06-10 | 2005-03-23 | Merck & Co Inc | Inhibidores de la 11-beta-hidroxiesteroide deshidrogrenasa 1 para el tratamiento de la diabetes obesidad y dislipidemia |
| JP4287816B2 (ja) * | 2002-06-13 | 2009-07-01 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー | ピラゾールカルボキサミド殺虫剤 |
| EP1549600A1 (en) | 2002-07-27 | 2005-07-06 | AstraZeneca AB | Ketones |
| US20050256159A1 (en) | 2002-10-11 | 2005-11-17 | Astrazeneca Ab | 1,4-disubstituted piperidine derivatives and their use as 11,betahsd1 inhibitors |
| JP2006514102A (ja) | 2002-11-07 | 2006-04-27 | アストラゼネカ アクチボラグ | ２−オキソ−エタンスルホンアミド誘導体 |
| US20040122033A1 (en) | 2002-12-10 | 2004-06-24 | Nargund Ravi P. | Combination therapy for the treatment of obesity |
| JO2397B1 (en) | 2002-12-20 | 2007-06-17 | ميرك شارب اند دوم كوربوريشن | Terazol derivatives as beta-hydroxy steroid dihydrogenase-1 inhibitors |
| TW200503994A (en) | 2003-01-24 | 2005-02-01 | Novartis Ag | Organic compounds |
| EP1615698B1 (en) * | 2003-04-11 | 2010-09-29 | High Point Pharmaceuticals, LLC | New amide derivatives and pharmaceutical use thereof |
| JP2006522744A (ja) | 2003-04-11 | 2006-10-05 | ノボ ノルディスク アクティーゼルスカブ | グルココルチコイド受容体アゴニスト療法に伴う副作用を最小化するための、１１β−ヒドロキシステロイドデヒドロゲナーゼ１型阻害剤およびグルココルチコイド受容体アゴニストを使用する併用療法 |
| JP2006522750A (ja) | 2003-04-11 | 2006-10-05 | ノボ ノルディスク アクティーゼルスカブ | 代謝性症候群ならびに関連の疾患および障害を治療するために、１１β−ヒドロキシステロイドデヒドロゲナーゼ１型阻害剤および抗高血圧剤を使用する併用療法 |
| WO2004089471A2 (en) | 2003-04-11 | 2004-10-21 | Novo Nordisk A/S | NEW PYRAZOLO[1,5-a] PYRIMIDINES DERIVATIVES AND PHARMACEUTICAL USE THEREOF |
| EP1631558A1 (en) | 2003-05-21 | 2006-03-08 | Biovitrum Ab | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type i |
| CN1795181A (zh) | 2003-05-29 | 2006-06-28 | 麦克公司 | 用作11β－羟基类固醇脱氢酶－1抑制剂的三唑衍生物 |
| SE0301883D0 (sv) | 2003-06-25 | 2003-06-25 | Biovitrum Ab | New use II |
| SE0301886D0 (sv) | 2003-06-25 | 2003-06-25 | Biovitrum Ab | New use V |
| AU2004265299B2 (en) * | 2003-08-07 | 2008-05-01 | Merck & Co., Inc. | Pyrazole carboxamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1 |
| EP1670460B1 (en) * | 2003-10-10 | 2014-11-26 | Bristol-Myers Squibb Company | Pyrazole derivatives as cannabinoid receptor modulators |
-
2006
- 2006-03-27 EP EP06725326A patent/EP1928840B1/en not_active Not-in-force
- 2006-03-27 AT AT06725326T patent/ATE519744T1/de active
- 2006-03-27 ES ES06725326T patent/ES2369389T3/es active Active
- 2006-03-27 AU AU2006232660A patent/AU2006232660B2/en not_active Ceased
- 2006-03-27 CA CA2602781A patent/CA2602781C/en not_active Expired - Fee Related
- 2006-03-27 KR KR1020077022649A patent/KR100931411B1/ko not_active Expired - Fee Related
- 2006-03-27 CN CN2006800111775A patent/CN101155783B/zh not_active Expired - Fee Related
- 2006-03-27 DK DK06725326.0T patent/DK1928840T3/da active
- 2006-03-27 BR BRPI0610459-2A patent/BRPI0610459A2/pt not_active IP Right Cessation
- 2006-03-27 RU RU2007140737/04A patent/RU2381217C2/ru not_active IP Right Cessation
- 2006-03-27 PL PL06725326T patent/PL1928840T3/pl unknown
- 2006-03-27 WO PCT/EP2006/061057 patent/WO2006106052A1/en not_active Ceased
- 2006-03-27 PT PT06725326T patent/PT1928840E/pt unknown
- 2006-03-27 MX MX2007012212A patent/MX2007012212A/es active IP Right Grant
- 2006-03-27 JP JP2008504736A patent/JP4880671B2/ja not_active Expired - Fee Related
- 2006-03-31 US US11/395,763 patent/US7345058B2/en not_active Expired - Fee Related
- 2006-04-03 AR ARP060101312A patent/AR053203A1/es unknown
- 2006-04-03 TW TW095111719A patent/TWI309645B/zh not_active IP Right Cessation
-
2007
- 2007-09-20 IL IL186118A patent/IL186118A0/en unknown
- 2007-09-25 NO NO20074872A patent/NO20074872L/no not_active Application Discontinuation
- 2007-10-02 ZA ZA200708419A patent/ZA200708419B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN101155783A (zh) | 2008-04-02 |
| EP1928840B1 (en) | 2011-08-10 |
| JP4880671B2 (ja) | 2012-02-22 |
| CN101155783B (zh) | 2012-01-04 |
| BRPI0610459A2 (pt) | 2010-06-22 |
| AR053203A1 (es) | 2007-04-25 |
| NO20074872L (no) | 2007-10-30 |
| AU2006232660B2 (en) | 2010-03-25 |
| PT1928840E (pt) | 2011-10-03 |
| AU2006232660A1 (en) | 2006-10-12 |
| JP2008534647A (ja) | 2008-08-28 |
| ZA200708419B (en) | 2008-11-26 |
| CA2602781C (en) | 2011-02-08 |
| RU2007140737A (ru) | 2009-05-20 |
| ATE519744T1 (de) | 2011-08-15 |
| ES2369389T3 (es) | 2011-11-30 |
| US7345058B2 (en) | 2008-03-18 |
| TW200643013A (en) | 2006-12-16 |
| RU2381217C2 (ru) | 2010-02-10 |
| KR100931411B1 (ko) | 2009-12-10 |
| KR20070108937A (ko) | 2007-11-13 |
| CA2602781A1 (en) | 2006-10-12 |
| EP1928840A1 (en) | 2008-06-11 |
| IL186118A0 (en) | 2008-01-20 |
| US20060223852A1 (en) | 2006-10-05 |
| MX2007012212A (es) | 2007-12-07 |
| TWI309645B (en) | 2009-05-11 |
| PL1928840T3 (pl) | 2012-01-31 |
| WO2006106052A1 (en) | 2006-10-12 |
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