DK1339679T3 - 3-Aroylindolderivater og deres anvendelse som agonister af CB2-receptorer - Google Patents

3-Aroylindolderivater og deres anvendelse som agonister af CB2-receptorer

Info

Publication number: DK1339679T3
Authority: DK; Denmark
Prior art keywords: aroylindole; agonists; receptors; derivatives; aroylindole derivatives
Prior art date: 2000-11-22

Application number

DK01997476T

Other languages

Danish (da)

English (en)

Inventor

Francis Barth

Carole Guillaumont

Fabienne Vasse

Claude Vernhet

Christian Congy

Murielle Rinaldi

Original Assignee

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-11-22

Filing date

2001-11-21

Publication date

2005-12-12

2001-11-21 Application filed by Sanofi Aventis filed Critical Sanofi Aventis

2005-12-12 Application granted granted Critical

2005-12-12 Publication of DK1339679T3 publication Critical patent/DK1339679T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Orthopedic Medicine & Surgery (AREA)
Pulmonology (AREA)
Immunology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Hematology (AREA)
Psychiatry (AREA)
Virology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Tropical Medicine & Parasitology (AREA)
Dermatology (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Obesity (AREA)
Ophthalmology & Optometry (AREA)
Molecular Biology (AREA)

DK01997476T 2000-11-22 2001-11-21 3-Aroylindolderivater og deres anvendelse som agonister af CB2-receptorer DK1339679T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR0015158A FR2816938B1 (fr)	2000-11-22	2000-11-22	Derives de 3-aroylindole, leur procede de preparation et les compositions pharmaceutiques en contenant

Publications (1)

Publication Number	Publication Date
DK1339679T3 true DK1339679T3 (da)	2005-12-12

Family

ID=8856819

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK01997476T DK1339679T3 (da)	2000-11-22	2001-11-21	3-Aroylindolderivater og deres anvendelse som agonister af CB2-receptorer

Country Status (32)

Country	Link
US (1)	US6995184B2 (de)
EP (1)	EP1339679B1 (de)
JP (1)	JP4264258B2 (de)
KR (1)	KR20030048161A (de)
CN (1)	CN1234688C (de)
AR (1)	AR033594A1 (de)
AT (1)	ATE301638T1 (de)
AU (1)	AU2002222001A1 (de)
BG (1)	BG107827A (de)
BR (1)	BR0115580A (de)
CA (1)	CA2427444A1 (de)
CZ (1)	CZ20031392A3 (de)
DE (1)	DE60112607T2 (de)
DK (1)	DK1339679T3 (de)
DZ (1)	DZ3443A1 (de)
EA (1)	EA005854B1 (de)
EE (1)	EE200300244A (de)
ES (1)	ES2247201T3 (de)
FR (1)	FR2816938B1 (de)
HR (1)	HRP20030417A2 (de)
HU (1)	HUP0400561A2 (de)
IL (1)	IL155634A0 (de)
IS (1)	IS6802A (de)
MA (1)	MA26959A1 (de)
MX (1)	MXPA03004549A (de)
NO (1)	NO20031952L (de)
NZ (1)	NZ525609A (de)
PL (1)	PL362276A1 (de)
SK (1)	SK6042003A3 (de)
TW (1)	TWI224592B (de)
WO (1)	WO2002042269A1 (de)
ZA (1)	ZA200303728B (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW200407110A (en) *	2001-11-23	2004-05-16	Astrazeneca Ab	New use for the treatment of gastroesophageal reflux disease
US7351729B2 (en)	2002-03-08	2008-04-01	Signal Pharmaceuticals, Llc	JNK inhibitors for use in combination therapy for treating or managing proliferative disorders and cancers
JP2006517194A (ja) *	2002-06-06	2006-07-20	イッサムリサーチディベロップメントカンパニーオブザヘブリューユニバーシティオブエルサレム	骨成長を調節するための方法、組成物および製造物
CA2494091C (en)	2002-08-02	2011-02-01	Richard B. Toupence	Substituted furo [2,3-b\| pyridine derivatives
FR2843964B1 (fr) *	2002-08-29	2004-10-01	Sanofi Synthelabo	Derives de dioxane-2-alkylcarbamates, leur preparation et leur application en therapeutique
FR2847899B1 (fr) *	2002-11-29	2006-04-28	Sanofi Synthelabo	Derives d'indole-3-carboxamide, leur preparation et leur application en therapeutique
FR2854633B1 (fr) *	2003-05-07	2005-06-24	Sanofi Synthelabo	Derives de piperidinyl-et piperazinyl-alkylcarbamates, leur preparation et leur application en therapeutique
FR2856684B1 (fr) *	2003-06-26	2008-04-11	Sanofi Synthelabo	Derives de diphenylpyridine, leur preparation et leur application en therapeutique
FR2865205B1 (fr) *	2004-01-16	2006-02-24	Sanofi Synthelabo	Derives de type aryloxyalkylcarbamates, leur preparation et leur application en therapeutique
EP1758566A2 (de) *	2004-06-22	2007-03-07	Pharmos Limited	Verwendung von agonisten des cb-2-rezeptors zur behandlung von chorea huntington
CA2586011C (en)	2004-07-12	2011-07-19	Cadila Healthcare Limited	Tricyclic pyrazole derivatives as cannabinoid receptor modulators
US20060025448A1 (en)	2004-07-22	2006-02-02	Cadila Healthcare Limited	Hair growth stimulators
AU2005309761A1 (en) *	2004-11-22	2006-06-01	Threshold Pharmaceuticals, Inc.	Tubulin binding anti cancer agents and prodrugs thereof
WO2006069196A1 (en) *	2004-12-21	2006-06-29	Abbott Laboratories	3-cycloalkylcarbonyl indoles as cannabinoid receptor ligands
FR2893615B1 (fr) *	2005-11-18	2008-03-07	Sanofi Aventis Sa	Derives de 3-acylindole, leur preparation et leur application en therapeutique
RU2306906C1 (ru) *	2006-04-21	2007-09-27	Федеральное государственное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова Федерального агентства по здравоохранению и социальному развитию"	Способ повышения зрительных функций при сублюксации хрусталика в случаях нарушения обмена в системе соединительной ткани
US8841334B2 (en) *	2006-05-31	2014-09-23	Abbvie Inc.	Compounds as cannabinoid receptor ligands and uses thereof
ES2645995T3 (es) *	2006-05-31	2017-12-11	Abbvie Inc.	Compuestos como ligandos del receptor cannabinoide y sus usos
GB0702862D0 (en) *	2007-02-14	2007-03-28	Univ Aberdeen	Therapeutic compounds
US7875640B2 (en)	2007-03-28	2011-01-25	Abbott Laboratories	Compounds as cannabinoid receptor ligands
US7872033B2 (en) *	2007-04-17	2011-01-18	Abbott Laboratories	Compounds as cannabinoid receptor ligands
FR2915199B1 (fr) *	2007-04-18	2010-01-22	Sanofi Aventis	Derives de triazolopyridine-carboxamides et triazolopyrimidine-carboxamides, leur preparation et leur application en therapeutique.
CN101711253A (zh)	2007-05-18	2010-05-19	雅培制药有限公司	用作大麻素受体配体的新化合物
US9193713B2 (en) *	2007-10-12	2015-11-24	Abbvie Inc.	Compounds as cannabinoid receptor ligands
FR2933697B1 (fr) *	2008-07-11	2010-08-13	Sanofi Aventis	Derives de 1-benzyl-cinnolin-4-(1h)-one substitues, leur preparation et leur application en therapeutique
US8846730B2 (en) *	2008-09-08	2014-09-30	Abbvie Inc.	Compounds as cannabinoid receptor ligands
EP2428507B1 (de) *	2008-09-16	2015-10-21	AbbVie Bahamas Ltd.	Cannabinoid-Rezeptorliganden
PA8854001A1 (es) *	2008-12-16	2010-07-27	Abbott Lab	Compuestos novedosos como ligandos de receptores de canabinoides
FR2941696B1 (fr)	2009-02-05	2011-04-15	Sanofi Aventis	Derives d'azaspiranyl-alkylcarbamates d'heterocycles a 5 chainons, leur preparation et leur application en therapeutique
FR2945533B1 (fr)	2009-05-12	2011-05-27	Sanofi Aventis	Derives de cyclopenta°c!pyrrolyl-alkylcarbamates d'heterocycles a 5 chainons, leur preparation et leur application en therapeutique
US20120277296A1 (en)	2009-07-23	2012-11-01	Sophie Lotersztajn	Selective CB2 Receptor Agonists for Use in the Prevention or Treatment of Alcoholic Liver Disease
FR2950055A1 (fr)	2009-09-17	2011-03-18	Sanofi Aventis	Derives de 3-amino-cinnolin-4(1h)-one substitues, leur preparation et leur application en therapeutique
US20130178453A1 (en) *	2010-02-09	2013-07-11	Ironwood Pharmaceuticals, Inc.	Cannabinoid Agonists
FR2983859B1 (fr)	2011-12-12	2014-01-17	Sanofi Sa	Derives de 1,3,5-triazine-2-amine, leur preparation et leur application en diagnostique et en therapeutique
AU2014354586A1 (en) *	2013-11-28	2016-06-16	Commonwealth Scientific And Industrial Research Organisation	Method of detecting plasmodium infection
CN108794379A (zh) *	2017-04-26	2018-11-13	华东师范大学	1h-吲哚-2-甲酰胺衍生物及其制备方法和应用
WO2022128050A1 (en)	2020-12-14	2022-06-23	Symrise Ag	Medicament for fighting inflammation and pain

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5532237A (en) *	1995-02-15	1996-07-02	Merck Frosst Canada, Inc.	Indole derivatives with affinity for the cannabinoid receptor
FR2735774B1 (fr) *	1995-06-21	1997-09-12	Sanofi Sa	Utilisation de composes agonistes du recepteur cb2 humain pour la preparation de medicaments immunomodulateurs, nouveaux composes agonistes du recepteur cb2 et les compositions pharmaceutiques les contenant
MXPA02005101A (es) *	1999-10-18	2003-09-25	Alexipharma Inc	Derivados de indol canabimimeticos.

2000
- 2000-11-22 FR FR0015158A patent/FR2816938B1/fr not_active Expired - Fee Related
2001
- 2001-11-21 EA EA200300453A patent/EA005854B1/ru not_active IP Right Cessation
- 2001-11-21 CA CA002427444A patent/CA2427444A1/fr not_active Abandoned
- 2001-11-21 EP EP01997476A patent/EP1339679B1/de not_active Expired - Lifetime
- 2001-11-21 DE DE60112607T patent/DE60112607T2/de not_active Expired - Lifetime
- 2001-11-21 US US10/416,617 patent/US6995184B2/en not_active Expired - Fee Related
- 2001-11-21 AT AT01997476T patent/ATE301638T1/de not_active IP Right Cessation
- 2001-11-21 KR KR10-2003-7006862A patent/KR20030048161A/ko not_active Withdrawn
- 2001-11-21 HR HR20030417A patent/HRP20030417A2/hr not_active Application Discontinuation
- 2001-11-21 CZ CZ20031392A patent/CZ20031392A3/cs unknown
- 2001-11-21 AR ARP010105425A patent/AR033594A1/es not_active Application Discontinuation
- 2001-11-21 NZ NZ525609A patent/NZ525609A/en unknown
- 2001-11-21 EE EEP200300244A patent/EE200300244A/xx unknown
- 2001-11-21 WO PCT/FR2001/003665 patent/WO2002042269A1/fr not_active Ceased
- 2001-11-21 DK DK01997476T patent/DK1339679T3/da active
- 2001-11-21 IL IL15563401A patent/IL155634A0/xx unknown
- 2001-11-21 CN CNB018211755A patent/CN1234688C/zh not_active Expired - Fee Related
- 2001-11-21 PL PL01362276A patent/PL362276A1/xx not_active Application Discontinuation
- 2001-11-21 BR BR0115580-6A patent/BR0115580A/pt not_active IP Right Cessation
- 2001-11-21 ES ES01997476T patent/ES2247201T3/es not_active Expired - Lifetime
- 2001-11-21 SK SK604-2003A patent/SK6042003A3/sk unknown
- 2001-11-21 DZ DZ013443A patent/DZ3443A1/fr active
- 2001-11-21 MX MXPA03004549A patent/MXPA03004549A/es active IP Right Grant
- 2001-11-21 HU HU0400561A patent/HUP0400561A2/hu unknown
- 2001-11-21 JP JP2002544405A patent/JP4264258B2/ja not_active Expired - Fee Related
- 2001-11-21 AU AU2002222001A patent/AU2002222001A1/en not_active Abandoned
- 2001-11-22 TW TW090128947A patent/TWI224592B/zh active
2003
- 2003-04-29 NO NO20031952A patent/NO20031952L/no unknown
- 2003-04-30 IS IS6802A patent/IS6802A/is unknown
- 2003-05-13 MA MA27157A patent/MA26959A1/fr unknown
- 2003-05-14 ZA ZA200303728A patent/ZA200303728B/en unknown
- 2003-05-19 BG BG107827A patent/BG107827A/bg unknown

Also Published As

Publication number	Publication date
NO20031952D0 (no)	2003-04-29
IL155634A0 (en)	2003-11-23
TWI224592B (en)	2004-12-01
FR2816938A1 (fr)	2002-05-24
EE200300244A (et)	2003-10-15
CZ20031392A3 (cs)	2003-09-17
MXPA03004549A (es)	2004-03-26
PL362276A1 (en)	2004-10-18
AR033594A1 (es)	2003-12-26
CN1234688C (zh)	2006-01-04
BG107827A (bg)	2004-01-30
ATE301638T1 (de)	2005-08-15
US20040034090A1 (en)	2004-02-19
JP2004514668A (ja)	2004-05-20
KR20030048161A (ko)	2003-06-18
NZ525609A (en)	2004-11-26
IS6802A (is)	2003-04-30
CN1483023A (zh)	2004-03-17
NO20031952L (no)	2003-07-22
EA005854B1 (ru)	2005-06-30
US6995184B2 (en)	2006-02-07
HUP0400561A2 (hu)	2004-07-28
DE60112607D1 (de)	2005-09-15
WO2002042269A1 (fr)	2002-05-30
BR0115580A (pt)	2003-09-09
CA2427444A1 (fr)	2002-05-30
ZA200303728B (en)	2004-05-14
EP1339679A1 (de)	2003-09-03
ES2247201T3 (es)	2006-03-01
SK6042003A3 (en)	2003-12-02
MA26959A1 (fr)	2004-12-20
AU2002222001A1 (en)	2002-06-03
HRP20030417A2 (en)	2003-08-31
DZ3443A1 (fr)	2002-05-30
EP1339679B1 (de)	2005-08-10
FR2816938B1 (fr)	2003-01-03
DE60112607T2 (de)	2006-06-14
EA200300453A1 (ru)	2003-10-30
JP4264258B2 (ja)	2009-05-13

Publication	Publication Date	Title
DK1339679T3 (da)	2005-12-12	3-Aroylindolderivater og deres anvendelse som agonister af CB2-receptorer
DK1309575T3 (da)	2005-09-12	Biphenylderivater og deres anvendelse som aktivatorer af PPAR-gamma-receptorerne
DK1438306T3 (da)	2014-06-23	Derivater af UK-2A
NO20026010D0 (no)	2002-12-13	Substituerte quinazolinderivater og deres anvendelse som inhibitorer
DK1539712T3 (da)	2008-03-17	Pyrimidinderivater og deres anvendelse som CB2-modulatorer
DK1170288T3 (da)	2004-11-29	Diphenylurinstofderivater og deres anvendelse som alfa2/5-HT2c-antagonister
DK1360169T3 (da)	2007-11-26	Succinatsalt af O-desmethyl-venlafaxin
DK1498413T3 (da)	2011-12-05	4-aminopicolinater og deres anvendelse som herbicider
NO20030471D0 (no)	2003-01-30	Karboksamidforbindelser og deres anvendelse som antagonister for en 11CBY-reseptor
DK1133477T3 (da)	2004-06-21	Substituerede benzimidazoler og deres anvendelse som parpinhibitorer
AR028567A1 (es)	2003-05-14	Nuevos derivados de fenil-propargileter
DK1307181T3 (da)	2006-01-30	Hidtil ukendte sammensætninger af minoxidil
NO20050077L (no)	2005-02-03	Substituerte heterocykliske derivater som er anvendelige som antidiabetes- og antiovervektsmidler
NO20044062L (no)	2004-10-26	N-aryl-2-oksazolidinon-5-karboksamider og deres derivater og deres anvendelse som antibakterielle midler
DK1505998T3 (da)	2014-10-06	Forbedret anvendelse af hop-syrer som antimikrobielle midler
AR028596A1 (es)	2003-05-14	Nuevos derivados de fenilglicina
NO20025150D0 (no)	2002-10-25	2-acylindolderivater og deres anvendelse som antitumormidler
DK1337521T3 (da)	2007-01-29	Salte af en isothiasol-4-carboxamid og deres anvendelse som antihyperproliferationsmiddel
NO20043580L (no)	2004-09-21	Quinazolinonderivater og deres bruk som CB agonister
DK1581518T3 (da)	2011-06-06	Substituerede 1-piperidin-4-yl-4-pyrrolidin-3-yl-piperazin-derivater og deres anvendelse som neurokinin antagonister
NO20030998D0 (no)	2003-03-04	Arylpiperazinderivater og deres anvendelse som psykotropiske midler
NO20030813D0 (no)	2003-02-21	Bifenylderivater og deres anvendelse som integrininhibitorer
NO20043173L (no)	2004-07-26	Benzotiazol- og benzoksazol-4,7-dionderivater og deres anvendelse som CDC25-fosfataseinhibitorer
DK1259515T3 (da)	2005-01-31	Thienopyridinderivater og deres anvendelse som antiinflammatoriske midler
IS6620A (is)	2002-11-14	Nýr fjölgervingur V af tórasemíði