DK1139755T3 - Fremgangsmåde til behandling af baterieinfektioner med rifalazil administreret én eller to gange om ugen - Google Patents
Fremgangsmåde til behandling af baterieinfektioner med rifalazil administreret én eller to gange om ugenInfo
- Publication number
- DK1139755T3 DK1139755T3 DK99968906T DK99968906T DK1139755T3 DK 1139755 T3 DK1139755 T3 DK 1139755T3 DK 99968906 T DK99968906 T DK 99968906T DK 99968906 T DK99968906 T DK 99968906T DK 1139755 T3 DK1139755 T3 DK 1139755T3
- Authority
- DK
- Denmark
- Prior art keywords
- infections
- twice
- rifalazil
- week
- administered once
- Prior art date
Links
- 208000015181 infectious disease Diseases 0.000 title abstract 4
- SGHWBDUXKUSFOP-KYALZUAASA-N rifalazil Chemical compound O([C@](C1=O)(C)O/C=C/[C@@H]([C@H]([C@@H](OC(C)=O)[C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)\C=C\C=C(C)/C(=O)N=C2C(=O)C=3C(O)=C4C)C)OC)C4=C1C=3C(NC1=C(O)C=3)=C2OC1=CC=3N1CCN(CC(C)C)CC1 SGHWBDUXKUSFOP-KYALZUAASA-N 0.000 title abstract 4
- 229950005007 rifalazil Drugs 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 208000035143 Bacterial infection Diseases 0.000 abstract 2
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 2
- 241001647372 Chlamydia pneumoniae Species 0.000 abstract 1
- 241000590002 Helicobacter pylori Species 0.000 abstract 1
- 241001502334 Mycobacterium avium complex bacterium Species 0.000 abstract 1
- 241000187479 Mycobacterium tuberculosis Species 0.000 abstract 1
- 229940037467 helicobacter pylori Drugs 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- 201000008827 tuberculosis Diseases 0.000 abstract 1
Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
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- A61K31/5375—1,4-Oxazines, e.g. morpholine
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- C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
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- C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
- C10M2207/00—Organic non-macromolecular hydrocarbon compounds containing hydrogen, carbon and oxygen as ingredients in lubricant compositions
- C10M2207/10—Carboxylix acids; Neutral salts thereof
- C10M2207/20—Rosin acids
- C10M2207/203—Rosin acids used as base material
-
- C—CHEMISTRY; METALLURGY
- C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
- C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
- C10M2207/00—Organic non-macromolecular hydrocarbon compounds containing hydrogen, carbon and oxygen as ingredients in lubricant compositions
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- C10M2207/24—Epoxidised acids; Ester derivatives thereof
- C10M2207/243—Epoxidised acids; Ester derivatives thereof used as base material
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- C—CHEMISTRY; METALLURGY
- C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
- C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
- C10M2209/00—Organic macromolecular compounds containing oxygen as ingredients in lubricant compositions
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- C—CHEMISTRY; METALLURGY
- C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
- C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
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- C—CHEMISTRY; METALLURGY
- C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
- C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
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- C10M2209/10—Macromolecular compoundss obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
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-
- C—CHEMISTRY; METALLURGY
- C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
- C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
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- C—CHEMISTRY; METALLURGY
- C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
- C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
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- C10M2209/107—Polyethers, i.e. containing di- or higher polyoxyalkylene groups of two or more specified different alkylene oxides covered by groups C10M2209/104 - C10M2209/106
- C10M2209/1075—Polyethers, i.e. containing di- or higher polyoxyalkylene groups of two or more specified different alkylene oxides covered by groups C10M2209/104 - C10M2209/106 used as base material
-
- C—CHEMISTRY; METALLURGY
- C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
- C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
- C10M2209/00—Organic macromolecular compounds containing oxygen as ingredients in lubricant compositions
- C10M2209/10—Macromolecular compoundss obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
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- C10M2209/108—Polyethers, i.e. containing di- or higher polyoxyalkylene groups etherified
- C10M2209/1085—Polyethers, i.e. containing di- or higher polyoxyalkylene groups etherified used as base material
-
- C—CHEMISTRY; METALLURGY
- C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
- C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
- C10M2209/00—Organic macromolecular compounds containing oxygen as ingredients in lubricant compositions
- C10M2209/10—Macromolecular compoundss obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
- C10M2209/103—Polyethers, i.e. containing di- or higher polyoxyalkylene groups
- C10M2209/109—Polyethers, i.e. containing di- or higher polyoxyalkylene groups esterified
- C10M2209/1095—Polyethers, i.e. containing di- or higher polyoxyalkylene groups esterified used as base material
-
- C—CHEMISTRY; METALLURGY
- C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
- C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
- C10M2209/00—Organic macromolecular compounds containing oxygen as ingredients in lubricant compositions
- C10M2209/12—Polysaccharides, e.g. cellulose, biopolymers
- C10M2209/123—Polysaccharides, e.g. cellulose, biopolymers used as base material
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
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| US11292198P | 1998-12-18 | 1998-12-18 |
Publications (1)
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| DK1139755T3 true DK1139755T3 (da) | 2006-08-21 |
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| EP (1) | EP1139755B9 (fr) |
| JP (1) | JP2004538236A (fr) |
| KR (1) | KR100634770B1 (fr) |
| CN (1) | CN1334702A (fr) |
| AT (1) | ATE324784T1 (fr) |
| AU (1) | AU2710600A (fr) |
| CA (1) | CA2355283C (fr) |
| DE (1) | DE69931183T2 (fr) |
| DK (1) | DK1139755T3 (fr) |
| ES (1) | ES2264281T3 (fr) |
| PT (1) | PT1139755E (fr) |
| WO (1) | WO2000035408A2 (fr) |
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| TW465235B (en) | 1998-09-17 | 2001-11-21 | United Video Properties Inc | Electronic program guide with digital storage |
| US6316433B1 (en) * | 1998-12-18 | 2001-11-13 | Kaneka Corporation | Method for treatment of bacterial infections with once or twice-weekly administered rifalazil |
| NZ523693A (en) * | 2000-07-10 | 2004-08-27 | Chiron Corp | Macrolide formulations for inhalation and methods of treatment of endobronchial infections |
| US7122525B2 (en) * | 2001-11-21 | 2006-10-17 | Activbiotics, Inc. | Targeted therapeutics and uses thereof |
| US20040077533A1 (en) * | 2002-05-23 | 2004-04-22 | Sayada Chalom B. | Methods and compositions for treating bacterial infections and diseases associated therewith |
| US20090149453A1 (en) * | 2002-05-23 | 2009-06-11 | Activbiotics Pharma Llc | Methods and compositions for treating bacterial infections and diseases associated therewith |
| EP1531828A4 (fr) * | 2002-05-23 | 2005-11-02 | Activbiotics Inc | Methodes de traitement d'infections bacteriennes et de maladies associees |
| AU2003239919A1 (en) * | 2002-06-03 | 2003-12-19 | Activbiotics, Inc. | Intravenous rifalazil formulation and methods of use thereof |
| JP2006501310A (ja) * | 2002-08-29 | 2006-01-12 | アクティブバイオティクス インコーポレイティッド | クロストリジウム・ディフィシレの感染およびそれに関係する疾患を治療するための方法および試薬 |
| WO2004024213A2 (fr) * | 2002-09-12 | 2004-03-25 | The Government Of The United States, As Represented By The Secretary Of The Department Of Health And Human Services | Aerosol de capreomycine pour l'inhibition de la tuberculose pulmonaire |
| US20070128124A1 (en) * | 2002-09-12 | 2007-06-07 | Kraus Carl N | Aerosolized capreomycin for inhibition of pulmonary tuberculosis |
| TW200418485A (en) * | 2002-09-23 | 2004-10-01 | Activbiotics Inc | Rifalazil compositions and therapeutic regimens |
| AU2003296963A1 (en) * | 2002-12-12 | 2004-07-09 | Activbiotics, Inc. | Methods and compositions for treating and preventing ear infections |
| WO2004054548A1 (fr) * | 2002-12-12 | 2004-07-01 | Activbiotics,Inc. | Methode et reactifs destines a traiter ou prevenir l'atherosclerose et des maladies qui lui sont associees |
| CN1894259A (zh) * | 2003-08-22 | 2007-01-10 | 活跃生物工艺学公司 | 利福霉素类似物及其应用 |
| US20060140990A1 (en) * | 2003-09-19 | 2006-06-29 | Drugtech Corporation | Composition for topical treatment of mixed vaginal infections |
| JP2007505927A (ja) * | 2003-09-19 | 2007-03-15 | ドラッグテック コーポレイション | 薬物送達システム |
| US7820652B2 (en) * | 2003-09-24 | 2010-10-26 | Activbiotics Pharma, Llc | Regimen for the administration of rifamycin-class antibiotics |
| US20050123602A1 (en) * | 2003-09-25 | 2005-06-09 | Michaelis Arthur F. | Rifalazil formulations |
| JP2007513961A (ja) * | 2003-12-10 | 2007-05-31 | アクティブバイオティクス インコーポレイティッド | リファマイシンアナログおよびその使用法 |
| CN1918172B (zh) * | 2003-12-23 | 2011-09-14 | 活跃生物工艺学公司 | 利福霉素类似物及其用途 |
| WO2006121979A2 (fr) * | 2005-05-09 | 2006-11-16 | Drugtech Corporation | Compositions pharmaceutiques a liberation modifiee |
| CN101228171A (zh) * | 2005-07-26 | 2008-07-23 | 默克勒有限公司 | 作为5-脂氧化酶和环加氧酶抑制剂的吡咯里嗪和中氮茚化合物的大环内酯偶联物 |
| US9205050B2 (en) | 2005-09-29 | 2015-12-08 | Bayer Intellectual Property Gmbh | Antibiotic formulations, unit doses, kits and methods |
| US20070112018A1 (en) * | 2005-10-06 | 2007-05-17 | Andrew Sternlicht | Treatment of peripheral arterial occlusive disease |
| BRPI0620908A2 (pt) * | 2006-01-05 | 2011-11-29 | Drugtech Corp | composição farmacêutica, sistema de distribuição antibacteriana e antifúngica vaginal e uso da composição farmacêutica |
| US20070154516A1 (en) * | 2006-01-05 | 2007-07-05 | Drugtech Corporation | Drug delivery system |
| CA2651159A1 (fr) * | 2006-04-06 | 2007-10-18 | Activbiotics Pharma Llc | Compositions pharmaceutiques et leurs utilisations |
| WO2012047893A2 (fr) * | 2010-10-04 | 2012-04-12 | Activbiotics Pharma, Llc | Utilisation de rifalazil et d'analogues de celui-ci pour le traitement de troubles oculaires |
| WO2012103119A1 (fr) * | 2011-01-24 | 2012-08-02 | Activbiotics Pharma, Llc | Compositions sous forme de doses unitaires s'administrant par voie orale, pour l'administration de rifalazil et d'autres agents antituberculeux |
| WO2012103116A1 (fr) * | 2011-01-24 | 2012-08-02 | Activbiotics Pharma, Llc | Administration par voie pulmonaire de rifalazil et d'analogues de celui-ci |
| EP2675275B1 (fr) | 2011-02-14 | 2017-12-20 | The Regents Of The University Of Michigan | Compositions et méthodes utilisables en vue du traitement de l'obésité et des troubles associés |
| RU2496475C2 (ru) | 2011-10-26 | 2013-10-27 | Александр Васильевич Иващенко | Фармацевтическая композиция и набор для лечения бактериальных инфекций |
| WO2013086415A1 (fr) * | 2011-12-09 | 2013-06-13 | The Regents Of The University Of Michigan | Composés antimicrobiens |
| WO2014179734A1 (fr) | 2013-05-02 | 2014-11-06 | The Regents Of The University Of Michigan | Amléxanox deutéré |
| EP3407974A4 (fr) | 2016-01-29 | 2019-08-28 | The Regents Of The University Of Michigan | Analogues d'amlexanox |
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| CA1304363C (fr) | 1988-11-01 | 1992-06-30 | Takehiko Yamane | Derive 3-hydroxybenzoxazinorifamycine, procede pour sa preparation et agent antibacterien en contenant |
| JP3347880B2 (ja) | 1994-06-22 | 2002-11-20 | 本田技研工業株式会社 | 車両用ルーフ、車両用ルーフの製造方法及び車両用ルーフの固定方法 |
| US5508015A (en) | 1994-07-15 | 1996-04-16 | E. I. Du Pont De Nemours And Company | Process for controlling agglomeration in the manufacture of TiO2 |
| EP0787494B1 (fr) * | 1995-09-01 | 2004-06-09 | Kaneka Corporation | Utilisation des derivates de rifamycine pour la manufacture d'un medicament contre les maladies causées par une infection par helicobacter pylori |
| JP3963976B2 (ja) | 1995-12-08 | 2007-08-22 | 株式会社カネカ | クラミジア感染症治療剤 |
| US6316433B1 (en) * | 1998-12-18 | 2001-11-13 | Kaneka Corporation | Method for treatment of bacterial infections with once or twice-weekly administered rifalazil |
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1999
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- 1999-12-16 JP JP2000587729A patent/JP2004538236A/ja active Pending
- 1999-12-16 ES ES99968906T patent/ES2264281T3/es not_active Expired - Lifetime
- 1999-12-16 EP EP99968906A patent/EP1139755B9/fr not_active Expired - Lifetime
- 1999-12-16 AU AU27106/00A patent/AU2710600A/en not_active Abandoned
- 1999-12-16 CN CN99815782A patent/CN1334702A/zh active Pending
- 1999-12-16 WO PCT/US1999/030101 patent/WO2000035408A2/fr not_active Ceased
- 1999-12-16 DE DE69931183T patent/DE69931183T2/de not_active Expired - Lifetime
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- 1999-12-16 KR KR1020017007717A patent/KR100634770B1/ko not_active Expired - Fee Related
- 1999-12-16 DK DK99968906T patent/DK1139755T3/da active
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2002
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Also Published As
| Publication number | Publication date |
|---|---|
| ATE324784T1 (de) | 2006-06-15 |
| DE69931183D1 (de) | 2006-06-08 |
| US6566354B1 (en) | 2003-05-20 |
| AU2710600A (en) | 2000-07-03 |
| US6316433B1 (en) | 2001-11-13 |
| WO2000035408A3 (fr) | 2000-11-02 |
| ES2264281T3 (es) | 2006-12-16 |
| KR100634770B1 (ko) | 2006-10-17 |
| CA2355283C (fr) | 2009-02-17 |
| JP2004538236A (ja) | 2004-12-24 |
| PT1139755E (pt) | 2006-08-31 |
| EP1139755A2 (fr) | 2001-10-10 |
| EP1139755B1 (fr) | 2006-05-03 |
| CA2355283A1 (fr) | 2000-06-22 |
| KR20020002365A (ko) | 2002-01-09 |
| US20030203903A1 (en) | 2003-10-30 |
| EP1139755A4 (fr) | 2003-01-02 |
| EP1139755B9 (fr) | 2006-07-05 |
| WO2000035408A2 (fr) | 2000-06-22 |
| CN1334702A (zh) | 2002-02-06 |
| DE69931183T2 (de) | 2007-02-01 |
| US7772228B2 (en) | 2010-08-10 |
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