PT1139755E - Metodo de tratamento de infeccoes bacterianas com rifalazil administado uma a duas vezes por semana - Google Patents
Metodo de tratamento de infeccoes bacterianas com rifalazil administado uma a duas vezes por semanaInfo
- Publication number
- PT1139755E PT1139755E PT99968906T PT99968906T PT1139755E PT 1139755 E PT1139755 E PT 1139755E PT 99968906 T PT99968906 T PT 99968906T PT 99968906 T PT99968906 T PT 99968906T PT 1139755 E PT1139755 E PT 1139755E
- Authority
- PT
- Portugal
- Prior art keywords
- treatment
- rifalazil
- bacterial infections
- per week
- twice per
- Prior art date
Links
- SGHWBDUXKUSFOP-KYALZUAASA-N rifalazil Chemical compound O([C@](C1=O)(C)O/C=C/[C@@H]([C@H]([C@@H](OC(C)=O)[C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)\C=C\C=C(C)/C(=O)N=C2C(=O)C=3C(O)=C4C)C)OC)C4=C1C=3C(NC1=C(O)C=3)=C2OC1=CC=3N1CCN(CC(C)C)CC1 SGHWBDUXKUSFOP-KYALZUAASA-N 0.000 title abstract 4
- 229950005007 rifalazil Drugs 0.000 title abstract 4
- 208000035143 Bacterial infection Diseases 0.000 title abstract 3
- 208000022362 bacterial infectious disease Diseases 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 208000015181 infectious disease Diseases 0.000 abstract 3
- 241001647372 Chlamydia pneumoniae Species 0.000 abstract 1
- 241000590002 Helicobacter pylori Species 0.000 abstract 1
- 241001502334 Mycobacterium avium complex bacterium Species 0.000 abstract 1
- 241000187479 Mycobacterium tuberculosis Species 0.000 abstract 1
- 229940037467 helicobacter pylori Drugs 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- 201000008827 tuberculosis Diseases 0.000 abstract 1
Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
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- C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
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- C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
- C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
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- C10M2207/203—Rosin acids used as base material
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- C—CHEMISTRY; METALLURGY
- C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
- C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
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- C10M2207/24—Epoxidised acids; Ester derivatives thereof
- C10M2207/243—Epoxidised acids; Ester derivatives thereof used as base material
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- C—CHEMISTRY; METALLURGY
- C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
- C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
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- C—CHEMISTRY; METALLURGY
- C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
- C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
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- C10M2209/1045—Polyethers, i.e. containing di- or higher polyoxyalkylene groups of alkylene oxides containing two carbon atoms only used as base material
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- C—CHEMISTRY; METALLURGY
- C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
- C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
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- C10M2209/1055—Polyethers, i.e. containing di- or higher polyoxyalkylene groups of alkylene oxides containing three carbon atoms only used as base material
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- C—CHEMISTRY; METALLURGY
- C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
- C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
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- C—CHEMISTRY; METALLURGY
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- C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
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- C—CHEMISTRY; METALLURGY
- C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
- C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
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- C10M2209/103—Polyethers, i.e. containing di- or higher polyoxyalkylene groups
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- C10M2209/1085—Polyethers, i.e. containing di- or higher polyoxyalkylene groups etherified used as base material
-
- C—CHEMISTRY; METALLURGY
- C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
- C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
- C10M2209/00—Organic macromolecular compounds containing oxygen as ingredients in lubricant compositions
- C10M2209/10—Macromolecular compoundss obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
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- C10M2209/1095—Polyethers, i.e. containing di- or higher polyoxyalkylene groups esterified used as base material
-
- C—CHEMISTRY; METALLURGY
- C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
- C10M—LUBRICATING COMPOSITIONS; USE OF CHEMICAL SUBSTANCES EITHER ALONE OR AS LUBRICATING INGREDIENTS IN A LUBRICATING COMPOSITION
- C10M2209/00—Organic macromolecular compounds containing oxygen as ingredients in lubricant compositions
- C10M2209/12—Polysaccharides, e.g. cellulose, biopolymers
- C10M2209/123—Polysaccharides, e.g. cellulose, biopolymers used as base material
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Pulmonology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (1)
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| US11292198P | 1998-12-18 | 1998-12-18 |
Publications (1)
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| PT1139755E true PT1139755E (pt) | 2006-08-31 |
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| CN (1) | CN1334702A (pt) |
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| ES (1) | ES2264281T3 (pt) |
| PT (1) | PT1139755E (pt) |
| WO (1) | WO2000035408A2 (pt) |
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| TW465235B (en) | 1998-09-17 | 2001-11-21 | United Video Properties Inc | Electronic program guide with digital storage |
| US6316433B1 (en) * | 1998-12-18 | 2001-11-13 | Kaneka Corporation | Method for treatment of bacterial infections with once or twice-weekly administered rifalazil |
| NZ523693A (en) * | 2000-07-10 | 2004-08-27 | Chiron Corp | Macrolide formulations for inhalation and methods of treatment of endobronchial infections |
| US7122525B2 (en) * | 2001-11-21 | 2006-10-17 | Activbiotics, Inc. | Targeted therapeutics and uses thereof |
| WO2003099217A2 (en) * | 2002-05-23 | 2003-12-04 | Activbiotics, Inc. | Methods of treating bacterial infections and diseases associated therewith |
| US20040077533A1 (en) * | 2002-05-23 | 2004-04-22 | Sayada Chalom B. | Methods and compositions for treating bacterial infections and diseases associated therewith |
| US20090149453A1 (en) * | 2002-05-23 | 2009-06-11 | Activbiotics Pharma Llc | Methods and compositions for treating bacterial infections and diseases associated therewith |
| US20040034021A1 (en) * | 2002-06-03 | 2004-02-19 | Michaelis Arthur F. | Intravenous rifalazil formulation and methods of use thereof |
| TW200500071A (en) * | 2002-08-29 | 2005-01-01 | Activbiotics Inc | Methods and reagents for treating infections of clostridium difficile and diseases associated therewith |
| US20070128124A1 (en) * | 2002-09-12 | 2007-06-07 | Kraus Carl N | Aerosolized capreomycin for inhibition of pulmonary tuberculosis |
| WO2004024213A2 (en) * | 2002-09-12 | 2004-03-25 | The Government Of The United States, As Represented By The Secretary Of The Department Of Health And Human Services | Aerosolized capreomycin for inhibition of pulmonary tuberculosis |
| TW200418485A (en) * | 2002-09-23 | 2004-10-01 | Activbiotics Inc | Rifalazil compositions and therapeutic regimens |
| AU2003296963A1 (en) * | 2002-12-12 | 2004-07-09 | Activbiotics, Inc. | Methods and compositions for treating and preventing ear infections |
| JP2006515294A (ja) * | 2002-12-12 | 2006-05-25 | アクティブバイオティクス インコーポレイティッド | アテローム性動脈硬化症およびその関連疾患を治療または予防するための方法および試薬 |
| JP2007503439A (ja) * | 2003-08-22 | 2007-02-22 | アクティブバイオティクス インコーポレイティッド | リファマイシンアナログおよびそれらの使用法 |
| BRPI0414500A (pt) * | 2003-09-19 | 2006-11-07 | Drugtech Corp | formulação farmacêutica composição para tratar uma infecção vaginal, e, métodos para tratar uma infecção vaginal, para estabilizar uma formulação de clindamicina, para tratar ou prevenir uma recorrência de uma infecção vaginal em uma paciente e para tratar condições vaginais |
| US20060140990A1 (en) * | 2003-09-19 | 2006-06-29 | Drugtech Corporation | Composition for topical treatment of mixed vaginal infections |
| US7820652B2 (en) * | 2003-09-24 | 2010-10-26 | Activbiotics Pharma, Llc | Regimen for the administration of rifamycin-class antibiotics |
| WO2005030142A2 (en) | 2003-09-25 | 2005-04-07 | Activbiotics, Inc. | Rifalazil formulations |
| EP1697382A4 (en) * | 2003-12-10 | 2008-11-05 | Activbiotics Inc | ANALOGUES OF RIFAMYCIN AND USES THEREOF |
| AU2004308399A1 (en) * | 2003-12-23 | 2005-07-14 | Activbiotics, Inc. | Rifamycin analogs and uses thereof |
| AU2006244260A1 (en) * | 2005-05-09 | 2006-11-16 | Drugtech Corporation | Modified-release pharmaceutical compositions |
| CN101228171A (zh) * | 2005-07-26 | 2008-07-23 | 默克勒有限公司 | 作为5-脂氧化酶和环加氧酶抑制剂的吡咯里嗪和中氮茚化合物的大环内酯偶联物 |
| MX348936B (es) | 2005-09-29 | 2017-07-03 | Nektar Therapeutics | Formulaciones de antibioticos, dosis unitarias, equipos y metodos. |
| TW200744605A (en) * | 2005-10-06 | 2007-12-16 | Activbiotics Inc | Treatment of peripheral arterial occlusive disease |
| WO2007079389A2 (en) * | 2006-01-05 | 2007-07-12 | Drugtech Corporation | Composition and method of use thereof |
| CN101365425A (zh) * | 2006-01-05 | 2009-02-11 | 药物技术公司 | 用于生物粘附到外阴阴道表面的递药系统 |
| CA2651159A1 (en) * | 2006-04-06 | 2007-10-18 | Activbiotics Pharma Llc | Pharmaceutical compositions and uses thereof |
| BR112013008186A2 (pt) * | 2010-10-04 | 2016-06-21 | Activbiotics Pharma Llc | uso de ripazil e análogos para tratar problemas oculares |
| WO2012103116A1 (en) * | 2011-01-24 | 2012-08-02 | Activbiotics Pharma, Llc | Pulmonary administration of rifalazil and analogs thereof |
| WO2012103119A1 (en) * | 2011-01-24 | 2012-08-02 | Activbiotics Pharma, Llc | Compositions for administering rifalazil and other anti-tuberculosis agents in unit dosage form for oral administration |
| EP2675275B1 (en) | 2011-02-14 | 2017-12-20 | The Regents Of The University Of Michigan | Compositions and methods for the treatment of obesity and related disorders |
| RU2496475C2 (ru) * | 2011-10-26 | 2013-10-27 | Александр Васильевич Иващенко | Фармацевтическая композиция и набор для лечения бактериальных инфекций |
| WO2013086415A1 (en) * | 2011-12-09 | 2013-06-13 | The Regents Of The University Of Michigan | Antimicrobial compounds |
| WO2014179734A1 (en) | 2013-05-02 | 2014-11-06 | The Regents Of The University Of Michigan | Deuterated amlexanox |
| EP3407974A4 (en) | 2016-01-29 | 2019-08-28 | The Regents Of The University Of Michigan | Amlexanox Analogs |
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| CA1304363C (en) | 1988-11-01 | 1992-06-30 | Takehiko Yamane | 3'-hydroxybenzoxazinorifamycin derivative, process for preparing the same and antibacterial agent containing the same |
| JP3347880B2 (ja) | 1994-06-22 | 2002-11-20 | 本田技研工業株式会社 | 車両用ルーフ、車両用ルーフの製造方法及び車両用ルーフの固定方法 |
| US5508015A (en) | 1994-07-15 | 1996-04-16 | E. I. Du Pont De Nemours And Company | Process for controlling agglomeration in the manufacture of TiO2 |
| ES2218597T3 (es) * | 1995-09-01 | 2004-11-16 | Kaneka Corporation | Uso de derivados de rifamicina para la fabricacion de un medicamento para el tratamiento de enfermedades causadas por infecciones de helicobacter pylori. |
| JP3963976B2 (ja) | 1995-12-08 | 2007-08-22 | 株式会社カネカ | クラミジア感染症治療剤 |
| US6316433B1 (en) * | 1998-12-18 | 2001-11-13 | Kaneka Corporation | Method for treatment of bacterial infections with once or twice-weekly administered rifalazil |
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- 1999-12-16 WO PCT/US1999/030101 patent/WO2000035408A2/en not_active Ceased
- 1999-12-16 ES ES99968906T patent/ES2264281T3/es not_active Expired - Lifetime
- 1999-12-16 PT PT99968906T patent/PT1139755E/pt unknown
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- 1999-12-16 EP EP99968906A patent/EP1139755B9/en not_active Expired - Lifetime
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2002
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Also Published As
| Publication number | Publication date |
|---|---|
| WO2000035408A2 (en) | 2000-06-22 |
| KR100634770B1 (ko) | 2006-10-17 |
| US6316433B1 (en) | 2001-11-13 |
| KR20020002365A (ko) | 2002-01-09 |
| CA2355283C (en) | 2009-02-17 |
| EP1139755B1 (en) | 2006-05-03 |
| AU2710600A (en) | 2000-07-03 |
| DE69931183T2 (de) | 2007-02-01 |
| WO2000035408A3 (en) | 2000-11-02 |
| ATE324784T1 (de) | 2006-06-15 |
| DK1139755T3 (da) | 2006-08-21 |
| EP1139755A4 (en) | 2003-01-02 |
| ES2264281T3 (es) | 2006-12-16 |
| CA2355283A1 (en) | 2000-06-22 |
| JP2004538236A (ja) | 2004-12-24 |
| US20030203903A1 (en) | 2003-10-30 |
| DE69931183D1 (de) | 2006-06-08 |
| EP1139755B9 (en) | 2006-07-05 |
| CN1334702A (zh) | 2002-02-06 |
| US6566354B1 (en) | 2003-05-20 |
| EP1139755A2 (en) | 2001-10-10 |
| US7772228B2 (en) | 2010-08-10 |
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