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DK0927249T3 - E2F ubiquitineringsdomæne og analyse til inhibitorer af E2F ubiquitinering - Google Patents

E2F ubiquitineringsdomæne og analyse til inhibitorer af E2F ubiquitinering

Info

Publication number
DK0927249T3
DK0927249T3 DK97936814T DK97936814T DK0927249T3 DK 0927249 T3 DK0927249 T3 DK 0927249T3 DK 97936814 T DK97936814 T DK 97936814T DK 97936814 T DK97936814 T DK 97936814T DK 0927249 T3 DK0927249 T3 DK 0927249T3
Authority
DK
Denmark
Prior art keywords
ubiquitination
domain
polypeptide
candidate
inhibitors
Prior art date
Application number
DK97936814T
Other languages
Danish (da)
English (en)
Inventor
Rene Bernards
Original Assignee
Topotarget Uk Ltd
Ver Nl Kanker Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Topotarget Uk Ltd, Ver Nl Kanker Inst filed Critical Topotarget Uk Ltd
Application granted granted Critical
Publication of DK0927249T3 publication Critical patent/DK0927249T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • C07K14/4705Regulators; Modulating activity stimulating, promoting or activating activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • C07K14/4703Inhibitors; Suppressors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Devices For Conveying Motion By Means Of Endless Flexible Members (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK97936814T 1996-08-23 1997-08-22 E2F ubiquitineringsdomæne og analyse til inhibitorer af E2F ubiquitinering DK0927249T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9617697.9A GB9617697D0 (en) 1996-08-23 1996-08-23 Assay
PCT/GB1997/002293 WO1998007852A1 (fr) 1996-08-23 1997-08-22 Domaine d'interaction du facteur e2f avec l'ubiquitine et analyses pour l'obtention d'inhibiteurs de cette interaction

Publications (1)

Publication Number Publication Date
DK0927249T3 true DK0927249T3 (da) 2005-03-14

Family

ID=10798859

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97936814T DK0927249T3 (da) 1996-08-23 1997-08-22 E2F ubiquitineringsdomæne og analyse til inhibitorer af E2F ubiquitinering

Country Status (12)

Country Link
US (1) US6368809B1 (fr)
EP (1) EP0927249B1 (fr)
JP (1) JP2000517178A (fr)
AT (1) ATE281520T1 (fr)
AU (1) AU3951097A (fr)
CA (1) CA2263803A1 (fr)
DE (1) DE69731478T2 (fr)
DK (1) DK0927249T3 (fr)
ES (1) ES2232880T3 (fr)
GB (1) GB9617697D0 (fr)
PT (1) PT927249E (fr)
WO (1) WO1998007852A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0963999A4 (fr) * 1996-09-30 2004-09-15 Kyowa Hakko Kogyo Kk Composes inhibant l'activite d'e2f
CA2409717A1 (fr) * 2000-05-12 2001-11-15 Prolifix Limited Dosage des modulateurs du cycle cellulaire basee sur la modulation de la deterioration de la cycline d1 en reponse a un rayonnement ionisant
AU2003282751A1 (en) * 2002-10-04 2004-05-04 Sloan-Kettering Institute For Cancer Research Liposomal system and method of using same
US7052843B2 (en) * 2002-10-08 2006-05-30 New York University Transcription-based assay for identification of post-translational modification and its application in proteomics
CN119751591B (zh) * 2025-03-06 2025-05-16 中南大学 一种靶向增稳brd7抑瘤蛋白的多肽及其在制备治疗实体肿瘤药物中的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6045999A (en) 1994-11-15 2000-04-04 Prolifix Limited Transcription factor E2F-4

Also Published As

Publication number Publication date
JP2000517178A (ja) 2000-12-26
DE69731478D1 (de) 2004-12-09
CA2263803A1 (fr) 1998-02-26
EP0927249B1 (fr) 2004-11-03
ATE281520T1 (de) 2004-11-15
DE69731478T2 (de) 2005-10-27
ES2232880T3 (es) 2005-06-01
AU3951097A (en) 1998-03-06
EP0927249A1 (fr) 1999-07-07
US6368809B1 (en) 2002-04-09
PT927249E (pt) 2005-03-31
GB9617697D0 (en) 1996-10-02
WO1998007852A1 (fr) 1998-02-26

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