DK0686192T3 - In vitro fremgangsmåde til at forøge fertilitet under tilstedeværelse inhibin/activinkombinationer - Google Patents

In vitro fremgangsmåde til at forøge fertilitet under tilstedeværelse inhibin/activinkombinationer

Info

Publication number: DK0686192T3
Authority: DK; Denmark
Prior art keywords: inhibin; activin; oocytes; combinations; vitro method
Prior art date: 1993-02-23

Application number

DK94909788T

Other languages

Danish (da)

English (en)

Inventor

Baha M Alak

Richard L Stouffer

Don P Wolf

Teresa K Woodruff

Original Assignee

Medical Res Foundation Of Oreg

Genentech Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-02-23

Filing date

1994-02-18

Publication date

2004-02-02

1994-02-18 Application filed by Medical Res Foundation Of Oreg, Genentech Inc filed Critical Medical Res Foundation Of Oreg

2004-02-02 Application granted granted Critical

2004-02-02 Publication of DK0686192T3 publication Critical patent/DK0686192T3/da

Links

102000005606 Activins Human genes 0.000 title abstract 3
108010059616 Activins Proteins 0.000 title abstract 3
239000000488 activin Substances 0.000 title abstract 3
239000000893 inhibin Substances 0.000 title abstract 3
ZPNFWUPYTFPOJU-LPYSRVMUSA-N iniprol Chemical compound C([C@H]1C(=O)NCC(=O)NCC(=O)N[C@H]2CSSC[C@H]3C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(N[C@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=4C=CC(O)=CC=4)C(=O)N[C@@H](CC=4C=CC=CC=4)C(=O)N[C@@H](CC=4C=CC(O)=CC=4)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC=4C=CC=CC=4)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC2=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CC=2C=CC=CC=2)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]2N(CCC2)C(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N2[C@@H](CCC2)C(=O)N2[C@@H](CCC2)C(=O)N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N2[C@@H](CCC2)C(=O)N3)C(=O)NCC(=O)NCC(=O)N[C@@H](C)C(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@H](C(=O)N1)C(C)C)[C@@H](C)O)[C@@H](C)CC)=O)[C@@H](C)CC)C1=CC=C(O)C=C1 ZPNFWUPYTFPOJU-LPYSRVMUSA-N 0.000 title abstract 3
238000000338 in vitro Methods 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
230000035558 fertility Effects 0.000 title 1
210000000287 oocyte Anatomy 0.000 abstract 5
238000012258 culturing Methods 0.000 abstract 3
230000004720 fertilization Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0608—Germ cells
- C12N5/0609—Oocytes, oogonia
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/02—Atmosphere, e.g. low oxygen conditions
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/60—Buffer, e.g. pH regulation, osmotic pressure
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/16—Activin; Inhibin; Mullerian inhibiting substance

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Cell Biology (AREA)
Developmental Biology & Embryology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Immunology (AREA)
Reproductive Health (AREA)
Veterinary Medicine (AREA)
Organic Chemistry (AREA)
Wood Science & Technology (AREA)
General Engineering & Computer Science (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Virology (AREA)
Microbiology (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Endocrinology (AREA)
Gynecology & Obstetrics (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Steroid Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Ink Jet (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

DK94909788T 1993-02-23 1994-02-18 In vitro fremgangsmåde til at forøge fertilitet under tilstedeværelse inhibin/activinkombinationer DK0686192T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/021,404 US5563059A (en)	1993-02-23	1993-02-23	Use of human inhibin and human activin to increase the number of mature primate oocytes
PCT/US1994/002008 WO1994019455A1 (fr)	1993-02-23	1994-02-18	Maturation in vitro d'oocytes en presence d'inhibine, d'activine ou de combinaisons d'inhibine/activine

Publications (1)

Publication Number	Publication Date
DK0686192T3 true DK0686192T3 (da)	2004-02-02

Family

ID=21804022

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK94909788T DK0686192T3 (da)	1993-02-23	1994-02-18	In vitro fremgangsmåde til at forøge fertilitet under tilstedeværelse inhibin/activinkombinationer

Country Status (11)

Country	Link
US (2)	US5563059A (fr)
EP (1)	EP0686192B1 (fr)
JP (1)	JPH08507211A (fr)
AT (1)	ATE250664T1 (fr)
AU (1)	AU672103B2 (fr)
CA (1)	CA2154447C (fr)
DE (1)	DE69433174T2 (fr)
DK (1)	DK0686192T3 (fr)
ES (1)	ES2208655T3 (fr)
PT (1)	PT686192E (fr)
WO (1)	WO1994019455A1 (fr)

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PT1100534E (pt)	1998-07-30	2008-03-28	Xy Inc	Sistema equino para inseminação artificial não-cirúrgica
US6485972B1 (en)	1998-10-15	2002-11-26	President And Fellows Of Harvard College	WNT signalling in reproductive organs
US6995251B1 (en)	1999-10-28	2006-02-07	Baylor	Ovary-specific genes and proteins
US20060079674A1 (en) *	1998-10-28	2006-04-13	Baylor College Of Medicine Wyeth	Contraceptive targets
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CA2394600A1 (fr) *	1999-12-17	2001-06-21	Oregon Health And Science University	Procedes de production d'animaux transgeniques
US7250292B2 (en) *	2000-01-26	2007-07-31	21St Century Medicine	Hypertonic reduction of chilling injury
CA2408939C (fr)	2000-05-09	2011-11-08	Xy, Inc.	Populations de spermatozoides tres purs, porteurs de chromosomes x et y
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WO2002043574A2 (fr) *	2000-11-29	2002-06-06	Xy, Inc.	Systeme de dissociation de spermatozoides congeles-decongeles porteurs d'un chromosome x de ceux porteurs d'un chromosome y
US7713687B2 (en)	2000-11-29	2010-05-11	Xy, Inc.	System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
US20030135876A1 (en) *	2002-01-16	2003-07-17	Larry Mobraaten	Maintenance of genetic lines using cryopreserved sperm
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US20050208651A1 (en) *	2002-03-08	2005-09-22	Ri-Cheng Chian	Vitro maturation of immature human oocytes
AU2012203441B2 (en) *	2002-05-17	2015-01-29	Mount Sinai School Of Medicine Of New York University	Mesoderm and definitive endoderm cell populations
WO2004098490A2 (fr) *	2002-05-17	2004-11-18	Mount Sinai School Of Medicine Of New York University	Population de cellules endodermiques definitives et mesodermiques
US20060003446A1 (en) *	2002-05-17	2006-01-05	Gordon Keller	Mesoderm and definitive endoderm cell populations
US8486618B2 (en)	2002-08-01	2013-07-16	Xy, Llc	Heterogeneous inseminate system
US8211629B2 (en)	2002-08-01	2012-07-03	Xy, Llc	Low pressure sperm cell separation system
CA2534394C (fr)	2002-08-15	2013-01-08	Xy, Inc.	Cytometre a flux haute resolution
US20040105858A1 (en) *	2002-08-29	2004-06-03	Kim Joanne Young Hee Kwak	Diagnosis and treatment of infertility
US7169548B2 (en)	2002-09-13	2007-01-30	Xy, Inc.	Sperm cell processing and preservation systems
DK2308419T3 (da)	2003-03-28	2016-06-06	Inguran Llc	Fremgangsmåde til bedømmelse af farvningstilstandene for dyresperm, som skal sorteres.
EP1625203B1 (fr)	2003-05-15	2015-04-08	Xy, Llc	Tri efficace de cellules haploides pour systemes de cytometrie en flux
DK1697504T3 (da)	2003-11-26	2011-11-14	Merck Serono Sa	Anvendelse af IL-6-type cytokiner til modning af oocytter
EP1730261A4 (fr) *	2004-03-10	2007-11-28	Univ California	Compositions et procedes pour faire croitre des cellules souches embryonnaires
WO2005095590A2 (fr)	2004-03-29	2005-10-13	Monsanto Technology Llc	Suspensions a spermatozoides pour le tri de leurs populations selon leur richesse en chromosomes x ou y
CA2566857A1 (fr)	2004-05-17	2005-12-01	The General Hospital Corporation	Procedes et compositions de production de cellules souches a partir de cellules souches de lignee germinale derivees de sang peripherique
AR049732A1 (es)	2004-07-22	2006-08-30	Monsanto Co	Proceso para enriquecer una poblacion de celulas de esperma
RU2281778C1 (ru) *	2005-04-21	2006-08-20	Мария Львовна Семенова	Способ культивирования зиготы и/или эмбриона и композиция для добавления в среду культивирования зигот и/или эмбрионов
RU2281777C1 (ru) *	2005-04-21	2006-08-20	Мария Львовна Семенова	Способ управления качеством ооцитов и композиция для добавления в среду культивирования ооцитов
US7618770B2 (en)	2005-07-29	2009-11-17	Xy, Inc.	Methods and apparatus for reducing protein content in sperm cell extenders
US8874380B2 (en)	2010-12-09	2014-10-28	Rutgers, The State University Of New Jersey	Method of overcoming therapeutic limitations of nonuniform distribution of radiopharmaceuticals and chemotherapy drugs
US20080113432A1 (en) *	2006-11-15	2008-05-15	Mariposa Biotechnology, Inc.	Methods and compositions for reanimating cryopreserved oocytes
US20080113431A1 (en) *	2006-11-15	2008-05-15	Mariposa Biotechnology, Inc.	Methods and compositions for cryopreserving oocytes
US8527209B2 (en)	2010-06-24	2013-09-03	The Invention Science Fund I, Llc	Rejuvenation or preservation of germ cells
SG194448A1 (en)	2011-04-14	2013-12-30	Gen Hospital Corp	Compositions and methods for autologous germline mitochondrial energy transfer
UA117448C2 (uk)	2011-06-29	2018-08-10	Зе Дженерел Хоспітел Корпорейшн	Середовище клітинної культури для культивування ооцита
CA3083301C (fr)	2017-11-23	2024-05-21	Biosearch, S.A.	Procede d'augmentation du taux d'implantation des embryons chez un sujet femelle souffrant du syndrome des ovaires polykystiques
WO2022094628A2 (fr) *	2020-11-02	2022-05-05	Conception Biosciences, Inc.	Dérivation in vitro de cellules somatiques gonadiques
CN114913972B (zh) *	2021-12-10	2023-12-01	北京大学第三医院（北京大学第三临床医学院）	预测受试者卵巢刺激过程中获得的卵母细胞数量的系统

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1993
- 1993-02-23 US US08/021,404 patent/US5563059A/en not_active Expired - Lifetime
1994
- 1994-02-18 EP EP94909788A patent/EP0686192B1/fr not_active Expired - Lifetime
- 1994-02-18 PT PT94909788T patent/PT686192E/pt unknown
- 1994-02-18 AU AU62497/94A patent/AU672103B2/en not_active Expired
- 1994-02-18 ES ES94909788T patent/ES2208655T3/es not_active Expired - Lifetime
- 1994-02-18 WO PCT/US1994/002008 patent/WO1994019455A1/fr not_active Ceased
- 1994-02-18 JP JP6519269A patent/JPH08507211A/ja active Pending
- 1994-02-18 CA CA002154447A patent/CA2154447C/fr not_active Expired - Lifetime
- 1994-02-18 AT AT94909788T patent/ATE250664T1/de active
- 1994-02-18 DK DK94909788T patent/DK0686192T3/da active
- 1994-02-18 DE DE69433174T patent/DE69433174T2/de not_active Expired - Lifetime
1995
- 1995-06-05 US US08/463,370 patent/US5693534A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP0686192B1 (fr)	2003-09-24
US5693534A (en)	1997-12-02
EP0686192A1 (fr)	1995-12-13
AU6249794A (en)	1994-09-14
DE69433174D1 (de)	2003-10-30
ATE250664T1 (de)	2003-10-15
ES2208655T3 (es)	2004-06-16
DE69433174T2 (de)	2004-07-01
PT686192E (pt)	2004-02-27
JPH08507211A (ja)	1996-08-06
US5563059A (en)	1996-10-08
CA2154447A1 (fr)	1994-09-01
AU672103B2 (en)	1996-09-19
WO1994019455A1 (fr)	1994-09-01
CA2154447C (fr)	2005-04-19

Publication	Publication Date	Title
DK0686192T3 (da)	2004-02-02	In vitro fremgangsmåde til at forøge fertilitet under tilstedeværelse inhibin/activinkombinationer
WO2002033047A3 (fr)	2002-10-10	Dispositif de culture d'embryons in vitro
IL109381A (en)	2000-08-31	Method of isolating enriching and selectively propagating animal stem cells an animal cell and a vector for use in genetically modifying same
ES2196502T3 (es)	2003-12-16	Composicion y metodo para inhibir el desarrollo de microorganismos que incluye hipobromito sodico estabilizado e isotiazolonas.
ATE290395T1 (de)	2005-03-15	Kirschextrakte zur hemmung von cyclooxygenaseenzymen
AU592747B2 (en)	1990-01-25	Method of freezing fertilized ova, spermatozoa or the like and apparatus therefor
DK0747471T3 (da)	2000-12-18	Proteasebehandlede og oprensede cellulase-sammensætninger samt fremgangsmåder til at reducere tilbagefarvning under enzymat
EP1088057A4 (fr)	2002-06-12	Procede et milieu pour la culture in vitro d'embryons humains
AU4613397A (en)	1998-05-15	Method for in vitro preconditioning of myoblasts before transplantation
CA2177043A1 (fr)	1995-05-26	Hepatoblastes et procede pour les isoler
EP0606847A3 (fr)	1995-04-26	Milieu pour la fertilisation in vitro et méthode de fertilisation in vitro.
NO912621L (no)	1991-08-28	Fremgangsmaate for innfoering av dna i animalske celler.
WO2000052142A3 (fr)	2001-03-22	Sterol activant la meiose et augmentant le taux d'implantations
NO20006545L (no)	2001-02-21	Fremgangsmåte for in vitro modning av humane kjönnsceller
MX9407877A (es)	1997-02-28	Sustrato de cultivo solido que incluye cebada.
WO1993023529A3 (fr)	1994-01-20	Culture stabilisee d'agregats cellulaires et procede de developpement des embryons a partir d'une souche proembryogene destine a la regeneration de la vigne
YAZICI et al.	2002	New records for the lichen flora of Turkey
EA199800918A1 (ru)	1999-04-29	Происходящие от хозяина сигналы для индуцирования экспрессии гена изопреноида и их применение
李明文 et al.	1996	One simple and rapid method for evaluating acrosome reaction of giant panda and other mammalian sperm
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