ATE250664T1 - In vitro reifen von oozyten mit inhibitin/activin kombinationen - Google Patents

In vitro reifen von oozyten mit inhibitin/activin kombinationen

Info

Publication number: ATE250664T1
Authority: AT; Austria
Prior art keywords: oocytes; activin; inhibitin; combinations; vitro
Prior art date: 1993-02-23

Application number

AT94909788T

Other languages

English (en)

Inventor

Baha M Alak

Richard L Stouffer

Don P Wolf

Teresa K Woodruff

Original Assignee

Genentech Inc

Medical Res Foundation Of Oreg

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-02-23

Filing date

1994-02-18

Publication date

2003-10-15

1994-02-18 Application filed by Genentech Inc, Medical Res Foundation Of Oreg filed Critical Genentech Inc

2003-10-15 Application granted granted Critical

2003-10-15 Publication of ATE250664T1 publication Critical patent/ATE250664T1/de

Links

210000000287 oocyte Anatomy 0.000 title abstract 6
102000005606 Activins Human genes 0.000 title abstract 3
108010059616 Activins Proteins 0.000 title abstract 3
239000000488 activin Substances 0.000 title abstract 3
238000000338 in vitro Methods 0.000 title abstract 2
108010080511 serum sodium transport inhibitor Proteins 0.000 title 1
238000012258 culturing Methods 0.000 abstract 3
239000000893 inhibin Substances 0.000 abstract 2
ZPNFWUPYTFPOJU-LPYSRVMUSA-N iniprol Chemical compound C([C@H]1C(=O)NCC(=O)NCC(=O)N[C@H]2CSSC[C@H]3C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(N[C@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=4C=CC(O)=CC=4)C(=O)N[C@@H](CC=4C=CC=CC=4)C(=O)N[C@@H](CC=4C=CC(O)=CC=4)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC=4C=CC=CC=4)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC2=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CC=2C=CC=CC=2)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]2N(CCC2)C(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N2[C@@H](CCC2)C(=O)N2[C@@H](CCC2)C(=O)N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N2[C@@H](CCC2)C(=O)N3)C(=O)NCC(=O)NCC(=O)N[C@@H](C)C(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@H](C(=O)N1)C(C)C)[C@@H](C)O)[C@@H](C)CC)=O)[C@@H](C)CC)C1=CC=C(O)C=C1 ZPNFWUPYTFPOJU-LPYSRVMUSA-N 0.000 abstract 2
230000004720 fertilization Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0608—Germ cells
- C12N5/0609—Oocytes, oogonia
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/02—Atmosphere, e.g. low oxygen conditions
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/60—Buffer, e.g. pH regulation, osmotic pressure
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/16—Activin; Inhibin; Mullerian inhibiting substance

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Zoology (AREA)
General Health & Medical Sciences (AREA)
Biotechnology (AREA)
Bioinformatics & Cheminformatics (AREA)
Cell Biology (AREA)
Developmental Biology & Embryology (AREA)
Veterinary Medicine (AREA)
Wood Science & Technology (AREA)
Genetics & Genomics (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Reproductive Health (AREA)
Immunology (AREA)
Epidemiology (AREA)
Medicinal Chemistry (AREA)
Microbiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gynecology & Obstetrics (AREA)
General Engineering & Computer Science (AREA)
Biochemistry (AREA)
Endocrinology (AREA)
Gastroenterology & Hepatology (AREA)
Virology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Steroid Compounds (AREA)
Ink Jet (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT94909788T 1993-02-23 1994-02-18 In vitro reifen von oozyten mit inhibitin/activin kombinationen ATE250664T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/021,404 US5563059A (en)	1993-02-23	1993-02-23	Use of human inhibin and human activin to increase the number of mature primate oocytes
PCT/US1994/002008 WO1994019455A1 (en)	1993-02-23	1994-02-18	In vitro maturation of oocytes with inhibin, activin or inhibin/activin combinations

Publications (1)

Publication Number	Publication Date
ATE250664T1 true ATE250664T1 (de)	2003-10-15

Family

ID=21804022

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94909788T ATE250664T1 (de)	1993-02-23	1994-02-18	In vitro reifen von oozyten mit inhibitin/activin kombinationen

Country Status (11)

Country	Link
US (2)	US5563059A (de)
EP (1)	EP0686192B1 (de)
JP (1)	JPH08507211A (de)
AT (1)	ATE250664T1 (de)
AU (1)	AU672103B2 (de)
CA (1)	CA2154447C (de)
DE (1)	DE69433174T2 (de)
DK (1)	DK0686192T3 (de)
ES (1)	ES2208655T3 (de)
PT (1)	PT686192E (de)
WO (1)	WO1994019455A1 (de)

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DK1100534T3 (da)	1998-07-30	2008-03-10	Xy Inc	System til ikke-kirurgisk kunstig insemination af heste
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US20020042926A1 (en) *	1998-10-28	2002-04-11	Matzuk Martin M.	Ovary-specific genes and proteins
US7335737B2 (en) *	1998-10-28	2008-02-26	Baylor College Of Medicine	Ovary-specific genes and proteins
US20060079674A1 (en) *	1998-10-28	2006-04-13	Baylor College Of Medicine Wyeth	Contraceptive targets
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CA2408939C (en)	2000-05-09	2011-11-08	Xy, Inc.	High purity x-chromosome bearing and y-chromosome bearing populations of spermatozoa
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AU2002220018A1 (en) *	2000-11-29	2002-06-11	Colorado State University	System for in-vitro fertilization with spermatozoa separated into x-chromosome and y-chromosome bearing populations
US7713687B2 (en)	2000-11-29	2010-05-11	Xy, Inc.	System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
US20030135876A1 (en) *	2002-01-16	2003-07-17	Larry Mobraaten	Maintenance of genetic lines using cryopreserved sperm
US6849394B2 (en) *	2002-02-21	2005-02-01	Minitube Of America	Compositions comprising reproductive cell media and methods for using such compositions
AU2003208232B2 (en) *	2002-03-08	2008-05-22	Mcgill University	In vitro maturation of immature human oocytes
AU2012203441B2 (en) *	2002-05-17	2015-01-29	Mount Sinai School Of Medicine Of New York University	Mesoderm and definitive endoderm cell populations
EP1543110A4 (de)	2002-05-17	2006-09-06	Sinai School Medicine	Mesoderm- und definitive endoderm-zellpopulationen
US20060003446A1 (en)	2002-05-17	2006-01-05	Gordon Keller	Mesoderm and definitive endoderm cell populations
US8486618B2 (en)	2002-08-01	2013-07-16	Xy, Llc	Heterogeneous inseminate system
JP4595067B2 (ja)	2002-08-01	2010-12-08	エックスワイ，エルエルシー	低圧精子細胞分離システム
WO2004017041A2 (en)	2002-08-15	2004-02-26	Xy, Inc.	High resolution flow cytometer
US20040105858A1 (en) *	2002-08-29	2004-06-03	Kim Joanne Young Hee Kwak	Diagnosis and treatment of infertility
US7169548B2 (en)	2002-09-13	2007-01-30	Xy, Inc.	Sperm cell processing and preservation systems
ES2930062T3 (es)	2003-03-28	2022-12-05	Inguran Llc	Aparato para detectar el punto de rotura de un sistema de generación de gotitas
AU2004242121B2 (en)	2003-05-15	2010-06-24	Xy, Llc.	Efficient haploid cell sorting for flow cytometer systems
ES2610161T3 (es) *	2003-11-26	2017-04-26	Merck Serono Sa	Uso de citocinas de tipo IL-6 para la maduración de ovocitos
EP1730261A4 (de) *	2004-03-10	2007-11-28	Univ California	Zusammensetzungen und verfahren zur anzucht embryonaler stammzellen
JP2007531523A (ja)	2004-03-29	2007-11-08	モンサントテクノロジーエルエルシー	Ｘまたはｙ染色体担持豊富化集団に仕分けるための精子懸濁液
AU2005257839A1 (en)	2004-05-17	2006-01-05	The General Hospital Corporation	Methods and compositions for producing germ cells from bone marrow derived germline stem cells
AR049732A1 (es)	2004-07-22	2006-08-30	Monsanto Co	Proceso para enriquecer una poblacion de celulas de esperma
RU2281778C1 (ru) *	2005-04-21	2006-08-20	Мария Львовна Семенова	Способ культивирования зиготы и/или эмбриона и композиция для добавления в среду культивирования зигот и/или эмбрионов
RU2281777C1 (ru) *	2005-04-21	2006-08-20	Мария Львовна Семенова	Способ управления качеством ооцитов и композиция для добавления в среду культивирования ооцитов
US7618770B2 (en)	2005-07-29	2009-11-17	Xy, Inc.	Methods and apparatus for reducing protein content in sperm cell extenders
US8874380B2 (en)	2010-12-09	2014-10-28	Rutgers, The State University Of New Jersey	Method of overcoming therapeutic limitations of nonuniform distribution of radiopharmaceuticals and chemotherapy drugs
US20080113432A1 (en) *	2006-11-15	2008-05-15	Mariposa Biotechnology, Inc.	Methods and compositions for reanimating cryopreserved oocytes
US20080113431A1 (en) *	2006-11-15	2008-05-15	Mariposa Biotechnology, Inc.	Methods and compositions for cryopreserving oocytes
US8445277B2 (en)	2010-06-24	2013-05-21	The Invention Science Fund I, Llc	Rejuvenation or preservation of germ cells
SG194448A1 (en)	2011-04-14	2013-12-30	Gen Hospital Corp	Compositions and methods for autologous germline mitochondrial energy transfer
AU2012276038B2 (en)	2011-06-29	2017-08-31	President And Fellows Of Harvard College	Compositions and methods for enhancing bioenergetic status in female germ cells
JP7257399B2 (ja)	2017-11-23	2023-04-13	バイオサーチ、ソシエダッド、アノニマ	多嚢胞性卵巣症候群に罹患している女性患者における胚着床率を高める方法
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CN114913972B (zh) *	2021-12-10	2023-12-01	北京大学第三医院（北京大学第三临床医学院）	预测受试者卵巢刺激过程中获得的卵母细胞数量的系统

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1993
- 1993-02-23 US US08/021,404 patent/US5563059A/en not_active Expired - Lifetime
1994
- 1994-02-18 PT PT94909788T patent/PT686192E/pt unknown
- 1994-02-18 AU AU62497/94A patent/AU672103B2/en not_active Expired
- 1994-02-18 DK DK94909788T patent/DK0686192T3/da active
- 1994-02-18 AT AT94909788T patent/ATE250664T1/de active
- 1994-02-18 DE DE69433174T patent/DE69433174T2/de not_active Expired - Lifetime
- 1994-02-18 ES ES94909788T patent/ES2208655T3/es not_active Expired - Lifetime
- 1994-02-18 EP EP94909788A patent/EP0686192B1/de not_active Expired - Lifetime
- 1994-02-18 JP JP6519269A patent/JPH08507211A/ja active Pending
- 1994-02-18 WO PCT/US1994/002008 patent/WO1994019455A1/en not_active Ceased
- 1994-02-18 CA CA002154447A patent/CA2154447C/en not_active Expired - Lifetime
1995
- 1995-06-05 US US08/463,370 patent/US5693534A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
WO1994019455A1 (en)	1994-09-01
PT686192E (pt)	2004-02-27
CA2154447C (en)	2005-04-19
DE69433174T2 (de)	2004-07-01
EP0686192B1 (de)	2003-09-24
DE69433174D1 (de)	2003-10-30
ES2208655T3 (es)	2004-06-16
EP0686192A1 (de)	1995-12-13
US5563059A (en)	1996-10-08
AU6249794A (en)	1994-09-14
AU672103B2 (en)	1996-09-19
US5693534A (en)	1997-12-02
DK0686192T3 (da)	2004-02-02
JPH08507211A (ja)	1996-08-06
CA2154447A1 (en)	1994-09-01

Publication	Publication Date	Title
ATE250664T1 (de)	2003-10-15	In vitro reifen von oozyten mit inhibitin/activin kombinationen
NO303261B1 (no)	1998-06-22	Apparat for plantekultivering
ATE193550T1 (de)	2000-06-15	Rekonstruiertes knorpelgewebe
GB9308271D0 (en)	1993-06-02	Method of isolating and/or enriching and/or selectively propagating pluripotential animal cells and animals for use in said method
DE3874019D1 (de)	1992-10-01	Verfahren zur konservierung von transplantierbaren, in vitro kultivierten epithelgeweben.
BG35465A3 (en)	1984-04-15	Method for preparing derivatives of 1-(cyclohexyl)-4-aryl-4- piperidine carbonic acid
NO305632B1 (no)	1999-07-05	TCMTB pÕ en fast bµrer i pulverform, fremgangsmÕte til fremstilling og anvendelse derav
GR3031518T3 (en)	2000-01-31	Selective system scan for multizone radiotelephone subscriber units.
AU566174B2 (en)	1987-10-08	Process to preserve acid-producing bacteria
BG41993A3 (en)	1987-09-15	Means and method for increase in cold resistance of plant cultures
FI851619A7 (fi)	1985-04-24	Menetelmä epifyyttikasviasetelmien kasvatusta ja kuljetusta varten.
CA2177043A1 (en)	1995-05-26	Hepatoblasts and method of isolating same
DE69535263D1 (de)	2006-11-23	Angiotensin ii zur verbesserung der befruchtung
TW349124B (en)	1999-01-01	Osmotically controlled fermentation process for the preparation of acarbose
NO20006545D0 (no)	2000-12-21	Fremgangsmåte for in vitro modning av humane kjönnsceller
DK4586A (da)	1986-07-08	Fremgangsmaade til formering af begoniearter
AU4075093A (en)	1993-12-13	Cellular aggregate stabilized culture and process for the development of embryos from a proembryogenic strain for use in vine regeneration techniques
DK0671121T3 (da)	2000-10-16	Hybriddyrkningsfremgangsmåder for kulturplanter i familien Brasicaceae
DE60040793D1 (de)	2008-12-24	Verfahren zur vermehrung von stammzellen
UA18979A (uk)	1997-12-25	Спосіб коhсервування сперми риб
AU1402495A (en)	1995-07-03	Use of macrophage depleting agents for prolonging the survival of non-autologus hematopoietic cell transplants and animal model assay systems
UA16856A1 (uk)	1997-08-29	Спосіб коhсервуваhhя ембріоhів ссавців
UA8596A1 (uk)	1996-09-30	Субстракт для вирощуваhhя істівhого гриба гливи звичайhої
MD638G2 (ro)	1997-07-31	Mediu pentru decongelarea spermei de taur
UA9924A (uk)	1996-09-30	Спосіб вирощування крупномірної деревини сосни

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