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PT686192E - Maturacao in vitro de cocitos com inibina activina ou combinacoes de inibina/activina - Google Patents

Maturacao in vitro de cocitos com inibina activina ou combinacoes de inibina/activina

Info

Publication number
PT686192E
PT686192E PT94909788T PT94909788T PT686192E PT 686192 E PT686192 E PT 686192E PT 94909788 T PT94909788 T PT 94909788T PT 94909788 T PT94909788 T PT 94909788T PT 686192 E PT686192 E PT 686192E
Authority
PT
Portugal
Prior art keywords
activin
inicine
inibin
activine
cookies
Prior art date
Application number
PT94909788T
Other languages
English (en)
Inventor
Baha M Alak
Richard L Stouffer
Don P Wolf
Teresa K Woodruff
Original Assignee
Genentech Inc
Univ Oregon Health & Science
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc, Univ Oregon Health & Science filed Critical Genentech Inc
Publication of PT686192E publication Critical patent/PT686192E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/54Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0608Germ cells
    • C12N5/0609Oocytes, oogonia
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/02Atmosphere, e.g. low oxygen conditions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/60Buffer, e.g. pH regulation, osmotic pressure
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/16Activin; Inhibin; Mullerian inhibiting substance

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Reproductive Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Ink Jet (AREA)
PT94909788T 1993-02-23 1994-02-18 Maturacao in vitro de cocitos com inibina activina ou combinacoes de inibina/activina PT686192E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/021,404 US5563059A (en) 1993-02-23 1993-02-23 Use of human inhibin and human activin to increase the number of mature primate oocytes

Publications (1)

Publication Number Publication Date
PT686192E true PT686192E (pt) 2004-02-27

Family

ID=21804022

Family Applications (1)

Application Number Title Priority Date Filing Date
PT94909788T PT686192E (pt) 1993-02-23 1994-02-18 Maturacao in vitro de cocitos com inibina activina ou combinacoes de inibina/activina

Country Status (11)

Country Link
US (2) US5563059A (pt)
EP (1) EP0686192B1 (pt)
JP (1) JPH08507211A (pt)
AT (1) ATE250664T1 (pt)
AU (1) AU672103B2 (pt)
CA (1) CA2154447C (pt)
DE (1) DE69433174T2 (pt)
DK (1) DK0686192T3 (pt)
ES (1) ES2208655T3 (pt)
PT (1) PT686192E (pt)
WO (1) WO1994019455A1 (pt)

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AU2008399A (en) * 1997-12-22 1999-07-12 President And Fellows Of Harvard College Method for cryopreserving oocytes
US6149867A (en) 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
US6071689A (en) 1997-12-31 2000-06-06 Xy, Inc. System for improving yield of sexed embryos in mammals
US6300311B1 (en) 1998-04-14 2001-10-09 Texas Tech University Regulation of vertebrate ovarian maturation and function using growth factors
US6143564A (en) * 1998-07-07 2000-11-07 University Of Hawaii Use of the polar body chromosomes for the production of embryos and normal offspring
CA2336220A1 (en) * 1998-07-24 2000-02-03 The Carnegie Institution Of Washington Method for maintenance and propagation of germline stem cells using members of the tgf-.beta. family of growth factors
CA2338194C (en) 1998-07-30 2013-09-10 Edward L. Squires Equine system for non-surgical artificial insemination
US6485972B1 (en) 1998-10-15 2002-11-26 President And Fellows Of Harvard College WNT signalling in reproductive organs
US20020042926A1 (en) * 1998-10-28 2002-04-11 Matzuk Martin M. Ovary-specific genes and proteins
US7335737B2 (en) * 1998-10-28 2008-02-26 Baylor College Of Medicine Ovary-specific genes and proteins
US20060079674A1 (en) * 1998-10-28 2006-04-13 Baylor College Of Medicine Wyeth Contraceptive targets
CA2348430A1 (en) * 1998-10-28 2000-05-04 Baylor College Of Medicine Ovary-specific genes and proteins
US6995251B1 (en) 1999-10-28 2006-02-07 Baylor Ovary-specific genes and proteins
WO2000050066A1 (en) 1999-02-24 2000-08-31 Novo Nordisk A/S Treatment of infertility
ATE361091T1 (de) 1999-02-24 2007-05-15 Novo Nordisk As Behandlung von unfruchtbarkeit
JP2002537801A (ja) * 1999-02-26 2002-11-12 ノボ ノルディスク アクティーゼルスカブ 着床率を増大させる減数分裂活性化ステロール
DE19910394A1 (de) * 1999-03-03 2000-09-07 Schering Ag Substanzen für die Fertilitätskontrolle
WO2000062809A1 (en) * 1999-04-19 2000-10-26 Kyowa Hakko Kogyo Co., Ltd. Proliferation inhibitor for androgen-independent tumor
EP1224276A4 (en) * 1999-10-29 2004-04-07 Nexia Biotech Inc PRODUCTION OF TRANSGENIC ANIMALS USING OVOCYTES OBTAINED BY LAPAROSCOPIC SAMPLING (LOPU)
US7208265B1 (en) 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
EP1241935A2 (en) * 1999-12-17 2002-09-25 Gerald Schatten Methods for producing transgenic animals
US7250292B2 (en) * 2000-01-26 2007-07-31 21St Century Medicine Hypertonic reduction of chilling injury
HUP0302232A2 (hu) 2000-05-09 2003-10-28 Xy, Inc. Berendezés és eljárás X-kromoszómát hordozó hímivarsejtek és Y-kromoszómát hordozó hímivarsejtek szétválogatására, eljárás részecskék megkülönböztetésére és részecskeosztályozó berendezés
RU2193777C2 (ru) * 2000-06-15 2002-11-27 Ростовский НИИ акушерства и педиатрии Способ прогнозирования исходов программы эко и пэ
AU2002220018A1 (en) * 2000-11-29 2002-06-11 Colorado State University System for in-vitro fertilization with spermatozoa separated into x-chromosome and y-chromosome bearing populations
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
US20030135876A1 (en) * 2002-01-16 2003-07-17 Larry Mobraaten Maintenance of genetic lines using cryopreserved sperm
US6849394B2 (en) * 2002-02-21 2005-02-01 Minitube Of America Compositions comprising reproductive cell media and methods for using such compositions
CA2477743C (en) * 2002-03-08 2011-11-08 Mcgill University In vitro maturation of immature human oocytes
US20060003446A1 (en) * 2002-05-17 2006-01-05 Gordon Keller Mesoderm and definitive endoderm cell populations
AU2012203441B2 (en) * 2002-05-17 2015-01-29 Mount Sinai School Of Medicine Of New York University Mesoderm and definitive endoderm cell populations
EP1543110A4 (en) * 2002-05-17 2006-09-06 Sinai School Medicine POPULATION OF DEFINITIVE ENDODERMIC CELLS AND MESODERMAL
WO2004012837A2 (en) 2002-08-01 2004-02-12 Xy, Inc. Low pressure sperm cell separation system
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
WO2004017041A2 (en) 2002-08-15 2004-02-26 Xy, Inc. High resolution flow cytometer
US20040105858A1 (en) * 2002-08-29 2004-06-03 Kim Joanne Young Hee Kwak Diagnosis and treatment of infertility
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
DK2305172T3 (en) 2003-03-28 2016-08-22 Inguran Llc DEVICE AND PROCEDURES TO PROVIDE SEXUAL ANIMAL SEED
ES2541121T3 (es) 2003-05-15 2015-07-16 Xy, Llc Clasificación eficiente de células haploides por sistemas de citometría de flujo
PT2325201T (pt) * 2003-11-26 2017-01-09 Merck Serono Sa Utilização de citocinas do tipo il-6 para a maturação de oócitos
WO2005086845A2 (en) * 2004-03-10 2005-09-22 Regents Of The University Of California Compositions and methods for growth of embryonic stem cells
BRPI0509485A (pt) 2004-03-29 2007-09-11 Monsanto Technology Llc suspensões de esperma para uso em inseminação
DK1765085T3 (en) 2004-05-17 2015-10-05 Gen Hospital Corp Compositions comprising female germline stem cells and methods of use thereof
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RU2281778C1 (ru) * 2005-04-21 2006-08-20 Мария Львовна Семенова Способ культивирования зиготы и/или эмбриона и композиция для добавления в среду культивирования зигот и/или эмбрионов
RU2281777C1 (ru) * 2005-04-21 2006-08-20 Мария Львовна Семенова Способ управления качеством ооцитов и композиция для добавления в среду культивирования ооцитов
US7618770B2 (en) 2005-07-29 2009-11-17 Xy, Inc. Methods and apparatus for reducing protein content in sperm cell extenders
US8874380B2 (en) 2010-12-09 2014-10-28 Rutgers, The State University Of New Jersey Method of overcoming therapeutic limitations of nonuniform distribution of radiopharmaceuticals and chemotherapy drugs
US20080113431A1 (en) * 2006-11-15 2008-05-15 Mariposa Biotechnology, Inc. Methods and compositions for cryopreserving oocytes
US20080113432A1 (en) * 2006-11-15 2008-05-15 Mariposa Biotechnology, Inc. Methods and compositions for reanimating cryopreserved oocytes
US8445277B2 (en) 2010-06-24 2013-05-21 The Invention Science Fund I, Llc Rejuvenation or preservation of germ cells
CA2832336C (en) 2011-04-14 2016-08-09 The General Hospital Corporation Compositions and methods for autologous germline mitochondrial energy transfer
JP6284475B2 (ja) 2011-06-29 2018-02-28 ザ ジェネラル ホスピタル コーポレイション 雌性生殖細胞における生体エネルギー状態を増強するための組成物及び方法
NZ765637A (en) 2017-11-23 2025-11-28 Biosearch S A Method for increasing embryo implantation rate in a female subject suffering polycystic ovary syndrome
US20250084372A1 (en) * 2020-11-02 2025-03-13 Conception Biosciences, Inc. In vitro derivation of gonadal somatic cells
CN114913972B (zh) * 2021-12-10 2023-12-01 北京大学第三医院(北京大学第三临床医学院) 预测受试者卵巢刺激过程中获得的卵母细胞数量的系统

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Also Published As

Publication number Publication date
ATE250664T1 (de) 2003-10-15
AU6249794A (en) 1994-09-14
US5693534A (en) 1997-12-02
AU672103B2 (en) 1996-09-19
DE69433174T2 (de) 2004-07-01
US5563059A (en) 1996-10-08
WO1994019455A1 (en) 1994-09-01
DE69433174D1 (de) 2003-10-30
ES2208655T3 (es) 2004-06-16
CA2154447A1 (en) 1994-09-01
EP0686192B1 (en) 2003-09-24
CA2154447C (en) 2005-04-19
JPH08507211A (ja) 1996-08-06
EP0686192A1 (en) 1995-12-13
DK0686192T3 (da) 2004-02-02

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