DK0582368T3 - Thienobenzodiazepinderivater til behandling af forstyrrelser i centralnervesystemet - Google Patents

Thienobenzodiazepinderivater til behandling af forstyrrelser i centralnervesystemet

Info

Publication number: DK0582368T3
Authority: DK; Denmark
Prior art keywords: treatment; nervous system; central nervous; system disorders; alkyl
Prior art date: 1992-05-29

Application number

DK93304102T

Other languages

Danish (da)

English (en)

Inventor

David Edward Tupper

John Fairhurst

Terrence Michael Hotten

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-05-29

Filing date

1993-05-26

Publication date

2001-02-05

1992-05-29 Priority claimed from GB929211379A external-priority patent/GB9211379D0/en

1993-04-30 Priority claimed from GB939309025A external-priority patent/GB9309025D0/en

1993-05-26 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

2001-02-05 Application granted granted Critical

2001-02-05 Publication of DK0582368T3 publication Critical patent/DK0582368T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Addiction (AREA)
Anesthesiology (AREA)
Otolaryngology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK93304102T 1992-05-29 1993-05-26 Thienobenzodiazepinderivater til behandling af forstyrrelser i centralnervesystemet DK0582368T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB929211379A GB9211379D0 (en)	1992-05-29	1992-05-29	Pharmaceutical compounds
GB939309025A GB9309025D0 (en)	1993-04-30	1993-04-30	Pharmaceutical compounds

Publications (1)

Publication Number	Publication Date
DK0582368T3 true DK0582368T3 (da)	2001-02-05

Family

ID=26300951

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK93304102T DK0582368T3 (da)	1992-05-29	1993-05-26	Thienobenzodiazepinderivater til behandling af forstyrrelser i centralnervesystemet

Country Status (21)

Country	Link
EP (1)	EP0582368B1 (el)
JP (1)	JP3219541B2 (el)
CN (1)	CN1043994C (el)
AT (1)	ATE198891T1 (el)
AU (1)	AU668159B2 (el)
CA (1)	CA2097016A1 (el)
CZ (1)	CZ282783B6 (el)
DE (1)	DE69329887T2 (el)
DK (1)	DK0582368T3 (el)
ES (1)	ES2153373T3 (el)
FI (1)	FI101538B1 (el)
GR (1)	GR3035587T3 (el)
HU (1)	HU218278B (el)
IL (1)	IL105827A (el)
MX (1)	MX9303124A (el)
MY (1)	MY109943A (el)
NO (1)	NO305125B1 (el)
NZ (1)	NZ247703A (el)
PT (1)	PT582368E (el)
RU (1)	RU2125574C1 (el)
TW (1)	TW268005B (el)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5457101A (en) *	1994-06-03	1995-10-10	Eli Lilly And Company	Thieno[1,5]benzoidiazepine use
US5574028A (en) *	1994-10-31	1996-11-12	Eli Lilly And Company	Method for treating anxiety
EG24221A (en) *	1995-03-24	2008-11-10	Lilly Co Eli	Process for preparing olanzapine
EG23659A (en) *	1995-03-24	2007-03-26	Lilly Co Eli	Process and crystal forms of methyl-thieno-benzodiazepine
CR5278A (es)	1995-03-24	1996-07-04	Lilly Co Eli	Formulacion oral de 2-metil-tieno-benzodiacepina
US5891461A (en) *	1995-09-14	1999-04-06	Cygnus, Inc.	Transdermal administration of olanzapine
JP2001508759A (ja) *	1996-03-25	2001-07-03	イーライ・リリー・アンド・カンパニー	片頭痛の処置法
CZ298198A3 (cs) *	1996-03-25	1999-06-16	Eli Lilly And Company	Farmaceutický přípravek
WO1997035586A1 (en) *	1996-03-25	1997-10-02	Eli Lilly And Company	Method for treating pain
WO1998011893A1 (en)	1996-09-23	1998-03-26	Eli Lilly And Company	Olanzapine dihydrate d
ZA978515B (en) *	1996-09-23	1999-03-23	Lilly Co Eli	Intermediates and process for preparing olanzapine
AU719788B2 (en) *	1996-09-24	2000-05-18	Eli Lilly And Company	Coated particle formulation
RU2185383C1 (ru) *	2001-05-22	2002-07-20	Институт молекулярной генетики РАН	ВЫСОКОМЕЧЕННЫЙ ТРИТИЕМ 2-МЕТИЛ-4-(4-МЕТИЛ-1-ПИПЕРАЗИНИЛ)-10Н-ТИЕНО[2,3-b][1,5]БЕНЗОДИАЗЕПИН
ES2926662T3 (es)	2012-08-21	2022-10-27	Janssen Pharmaceutica Nv	Anticuerpos contra haptenos de risperidona y uso de los mismos
US9303041B2 (en) *	2012-08-21	2016-04-05	Janssen Pharmaceutica Nv	Haptens of olanzapine
EP2888234B1 (en)	2012-08-21	2017-12-06	Janssen Pharmaceutica NV	Haptens of aripiprazole and their use in immunoassays
AU2013305930B2 (en)	2012-08-21	2017-08-24	Saladax Biomedical Inc.	Haptens of paliperidone
ES2822004T3 (es)	2012-08-21	2021-04-28	Janssen Pharmaceutica Nv	Anticuerpos contra quetiapina y uso de los mismos
US9304126B2 (en)	2012-08-21	2016-04-05	Janssen Pharmaceutica Nv	Haptens of quetiapine
AU2013305970B2 (en)	2012-08-21	2017-08-17	Saladax Biomedical Inc.	Antibodies to aripiprazole haptens and use thereof
ES2807902T3 (es)	2012-08-21	2021-02-24	Janssen Pharmaceutica Nv	Anticuerpos para olanzapina y uso de los mismos
CN104736566A (zh)	2012-08-21	2015-06-24	奥索临床诊断有限公司	帕潘立酮半抗原的抗体及其用途
EP3415516B1 (en)	2012-08-21	2021-12-15	Janssen Pharmaceutica NV	Haptens of risperidone and paliperidone
TR201816416T4 (tr)	2012-08-21	2018-11-21	Janssen Pharmaceutica Nv	Risperidona yönelik antikorlar ve bunların kullanımı.
TR201910347T4 (tr)	2012-08-21	2019-07-22	Janssen Pharmaceutica Nv	Olanzapin haptenlerine yönelik antikorlar ve bunların kullanımı.
WO2014031630A2 (en)	2012-08-21	2014-02-27	Ortho-Clinical Diagnostics, Inc	Antibodies to paliperidone and use thereof
EP3663316A1 (en)	2012-08-21	2020-06-10	Janssen Pharmaceutica NV	Antibodies to aripiprazole and use thereof
PL2888286T3 (pl)	2012-08-21	2018-07-31	Janssen Pharmaceutica Nv	Przeciwciała skierowane przeciwko haptenom kwetiapinowym i ich zastosowanie
WO2017106508A1 (en)	2015-12-17	2017-06-22	Janssen Pharmaceutica Nv	Antibodies to quetiapine and use thereof
WO2017106501A1 (en)	2015-12-17	2017-06-22	Janssen Pharmaceutica Nv	Antibodies to risperidone and use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3962248A (en) *	1972-04-04	1976-06-08	Sandoz, Inc.	Process for making 11-piperazino-diazepines, oxazepines, thiazepines and azepines
CH569731A5 (el) *	1972-04-04	1975-11-28	Wander Ag Dr A
SU629879A3 (ru) *	1974-11-26	1978-10-25	Лилли Индастриз Лимитед, (Фирма)	Способ получени тиено(1,5) бензодиазепинов или их солей
US4061752A (en) *	1975-08-06	1977-12-06	Sandoz Ltd.	6-Piperazino-11-methylene-dibenzazepines[b,e]
DK416476A (da) *	1975-09-24	1977-03-25	Sandoz Ag	Fremgangsmade til fremstilling af diazepinderivater
CH624682A5 (el) *	1976-11-10	1981-08-14	Sandoz Ag
US4761411A (en) *	1983-05-18	1988-08-02	Hoechst-Roussel Pharmaceuticals Inc.	Dihydrobenzopyrrolobenzodiazepines useful for treating pyschoses
GB9009229D0 (en) *	1990-04-25	1990-06-20	Lilly Industries Ltd	Pharmaceutical compounds

1993
- 1993-05-26 NZ NZ247703A patent/NZ247703A/en unknown
- 1993-05-26 ES ES93304102T patent/ES2153373T3/es not_active Expired - Lifetime
- 1993-05-26 DE DE69329887T patent/DE69329887T2/de not_active Expired - Fee Related
- 1993-05-26 TW TW082104161A patent/TW268005B/zh active
- 1993-05-26 EP EP93304102A patent/EP0582368B1/en not_active Expired - Lifetime
- 1993-05-26 NO NO931917A patent/NO305125B1/no not_active IP Right Cessation
- 1993-05-26 PT PT93304102T patent/PT582368E/pt unknown
- 1993-05-26 AT AT93304102T patent/ATE198891T1/de not_active IP Right Cessation
- 1993-05-26 DK DK93304102T patent/DK0582368T3/da active
- 1993-05-26 AU AU39807/93A patent/AU668159B2/en not_active Ceased
- 1993-05-26 CA CA002097016A patent/CA2097016A1/en not_active Abandoned
- 1993-05-27 MX MX9303124A patent/MX9303124A/es not_active IP Right Cessation
- 1993-05-28 JP JP12642993A patent/JP3219541B2/ja not_active Expired - Fee Related
- 1993-05-28 IL IL10582793A patent/IL105827A/xx not_active IP Right Cessation
- 1993-05-28 CZ CZ931024A patent/CZ282783B6/cs not_active IP Right Cessation
- 1993-05-28 CN CN93108212A patent/CN1043994C/zh not_active Expired - Fee Related
- 1993-05-28 MY MYPI93001036A patent/MY109943A/en unknown
- 1993-05-28 RU RU93005057A patent/RU2125574C1/ru active
- 1993-05-28 HU HU9301579A patent/HU218278B/hu not_active IP Right Cessation
- 1993-05-28 FI FI932445A patent/FI101538B1/fi active
2001
- 2001-03-15 GR GR20010400431T patent/GR3035587T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE69329887T2 (de)	2001-05-23
CZ102493A3 (en)	1993-12-15
IL105827A0 (en)	1993-09-22
NO931917D0 (no)	1993-05-26
ES2153373T3 (es)	2001-03-01
HUT66180A (en)	1994-09-28
NZ247703A (en)	1995-07-26
GR3035587T3 (en)	2001-06-29
IL105827A (en)	1997-02-18
PT582368E (pt)	2001-05-31
AU668159B2 (en)	1996-04-26
EP0582368A1 (en)	1994-02-09
CN1043994C (zh)	1999-07-07
JPH0687862A (ja)	1994-03-29
MX9303124A (es)	1993-11-01
NO931917L (no)	1993-11-30
HU9301579D0 (en)	1993-09-28
FI932445A0 (fi)	1993-05-28
AU3980793A (en)	1993-12-02
JP3219541B2 (ja)	2001-10-15
NO305125B1 (no)	1999-04-06
CA2097016A1 (en)	1993-11-30
MY109943A (en)	1997-10-31
HU218278B (en)	2000-07-28
DE69329887D1 (de)	2001-03-01
CN1085903A (zh)	1994-04-27
FI932445L (fi)	1993-11-30
TW268005B (el)	1996-01-11
EP0582368B1 (en)	2001-01-24
FI101538B (fi)	1998-07-15
RU2125574C1 (ru)	1999-01-27
CZ282783B6 (cs)	1997-10-15
FI101538B1 (fi)	1998-07-15
ATE198891T1 (de)	2001-02-15

Publication	Publication Date	Title
DK0582368T3 (da)	2001-02-05	Thienobenzodiazepinderivater til behandling af forstyrrelser i centralnervesystemet
ATE103812T1 (de)	1994-04-15	Zusammensetzung zur behandlung von ischaemischen stoerungen in organen.
ES2054020T3 (es)	1994-08-01	Compuestos biologicamente activos.
NO821494L (no)	1982-11-09	Terapeutisk nyttige 1-alkyl-2-aminotetralinderivater
MX9202803A (es)	1992-12-01	Nuevos compuestos de benzopirano y procedimiento para su preparacion.
MD1560F2 (en)	2000-11-30	Cyclic compounds, pharmaceutical compositions on base thereof and methods of treatment of infections or diseases provoked by retroviruses.
MX9300875A (es)	1993-08-31	Procedimiento para la preparacion de compuestos azabiciclicos.
DK0594099T3 (da)	1999-02-15	Fremgangsmåde til rensning af rå clavulansyre
ATE264104T1 (de)	2004-04-15	Immunmodulierende arzneimittelzusammenstellung
ATE98230T1 (de)	1993-12-15	Indolderivate.
ATE186912T1 (de)	1999-12-15	Carbamoylpyrrolidon-derivate zur behandlung von depressionen und cerebrovasculären störungen
DE69527854D1 (de)	2002-09-26	Derivate substituierter amidinonaphthylester
PT889044E (pt)	2005-01-31	Derivados do 5-(heteroaril)alquil-3-oxo-pirido-(1,2-a)benzimidazole-4-carboxamida (pbi) uteis no tratamento de perturbacoes do sistema nervoso central
DE3867494D1 (de)	1992-02-20	Fluor enthaltende vitamin-d2-derivate.
DK0501442T3 (da)	1996-01-08	8-Chlor-benzothiazepin-forbindelse til forebyggelse og behandling af følgerne af cerebral nekrose af nerveceller
ES2133095A1 (es)	1999-08-16	Acidos alquilidenglutaminicos con propiedades farmaceuticas.