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DK0483667T3 - Cykliske iminoderivater, lægemidler indholdende disse forbindelser og fremgangsmåde til fremstilling deraf - Google Patents

Cykliske iminoderivater, lægemidler indholdende disse forbindelser og fremgangsmåde til fremstilling deraf

Info

Publication number
DK0483667T3
DK0483667T3 DK91118148T DK91118148T DK0483667T3 DK 0483667 T3 DK0483667 T3 DK 0483667T3 DK 91118148 T DK91118148 T DK 91118148T DK 91118148 T DK91118148 T DK 91118148T DK 0483667 T3 DK0483667 T3 DK 0483667T3
Authority
DK
Denmark
Prior art keywords
compounds
preparation
drugs containing
cyclic imino
processes
Prior art date
Application number
DK91118148T
Other languages
English (en)
Inventor
Frank Dr Dipl-Chem Himmelsbach
Volkhard Dr Dipl-Chem Austel
Helmut Dr Dipl-Chem Pieper
Wolfgang Prof Dr Dr Dr Eisert
Thomas Dr Dipl-Chem Mueller
Johannes Dr Dipl- Weisenberger
Guenter Dr Dipl-Chem Linz
Gerd Dr Dipl-Chem Krueger
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Application granted granted Critical
Publication of DK0483667T3 publication Critical patent/DK0483667T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/572—Five-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Detergent Compositions (AREA)
  • Indole Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
DK91118148T 1990-11-02 1991-10-24 Cykliske iminoderivater, lægemidler indholdende disse forbindelser og fremgangsmåde til fremstilling deraf DK0483667T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4035961A DE4035961A1 (de) 1990-11-02 1990-11-02 Cyclische iminoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
DK0483667T3 true DK0483667T3 (da) 1998-09-23

Family

ID=6418111

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91118148T DK0483667T3 (da) 1990-11-02 1991-10-24 Cykliske iminoderivater, lægemidler indholdende disse forbindelser og fremgangsmåde til fremstilling deraf

Country Status (25)

Country Link
US (2) US5541343A (da)
EP (1) EP0483667B1 (da)
JP (1) JP2937589B2 (da)
KR (1) KR100223135B1 (da)
AT (1) ATE163008T1 (da)
BG (1) BG62025B2 (da)
BR (1) BR1100445A (da)
CA (1) CA2054850C (da)
DE (2) DE4035961A1 (da)
DK (1) DK0483667T3 (da)
EE (1) EE03099B1 (da)
ES (1) ES2113867T3 (da)
FI (1) FI107606B (da)
GR (1) GR3026508T3 (da)
HK (1) HK1008742A1 (da)
HU (2) HUT67288A (da)
IE (1) IE913822A1 (da)
IL (1) IL99926A (da)
MX (1) MX9203677A (da)
NO (1) NO174806B (da)
NZ (1) NZ240463A (da)
PT (1) PT99402B (da)
RU (1) RU2040519C1 (da)
SG (1) SG81852A1 (da)
ZA (1) ZA918734B (da)

Families Citing this family (90)

* Cited by examiner, † Cited by third party
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US10358422B2 (en) 2017-11-01 2019-07-23 California Institute Of Technology Methods for enantioselective allylic alkylation of esters, lactones, and lactams with unactivated allylic alcohols
EP3699173A1 (en) 2018-10-18 2020-08-26 California Institute of Technology Gem-disubstituted pyrrolidines, piperazines, and diazepanes, and compositions and methods of making the same

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GR3026508T3 (en) 1998-07-31
AU650488B2 (en) 1994-06-23
EP0483667A3 (en) 1992-09-16
HU913455D0 (en) 1992-01-28
CA2054850A1 (en) 1992-05-03
AU8692691A (en) 1992-05-07
IL99926A (en) 1996-06-18
EP0483667A2 (de) 1992-05-06
FI915136A0 (fi) 1991-10-31
NO914294D0 (no) 1991-11-01
KR920009793A (ko) 1992-06-25
FI107606B (fi) 2001-09-14
FI915136L (fi) 1992-05-03
IE913822A1 (en) 1992-05-22
ATE163008T1 (de) 1998-02-15
US5541343A (en) 1996-07-30
CA2054850C (en) 2001-01-02
JPH04264068A (ja) 1992-09-18
MX9203677A (es) 1992-07-01
NZ240463A (en) 1997-04-24
ES2113867T3 (es) 1998-05-16
ZA918734B (en) 1993-05-04
DE4035961A1 (de) 1992-05-07
NO174806B (no) 1994-04-05
US5591769A (en) 1997-01-07
NO914294L (no) 1992-05-04
SG81852A1 (en) 2001-07-24
PT99402A (pt) 1992-09-30
BR1100445A (pt) 2000-07-18
IL99926A0 (en) 1992-08-18
NO174806C (da) 1994-07-13
HU211563A9 (en) 1995-12-28
EP0483667B1 (de) 1998-02-04
PT99402B (pt) 1999-04-30
BG62025B2 (bg) 1998-12-30
JP2937589B2 (ja) 1999-08-23
EE03099B1 (et) 1998-06-15
RU2040519C1 (ru) 1995-07-25
HUT67288A (en) 1995-03-28
KR100223135B1 (ko) 1999-10-15
DE59108930D1 (de) 1998-03-12
HK1008742A1 (en) 1999-05-14

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