[go: up one dir, main page]

CY1111476T1 - Αλογονωμενα αντι-μιτωτικα παραγωγα των αλκαλοειδων της vinca - Google Patents

Αλογονωμενα αντι-μιτωτικα παραγωγα των αλκαλοειδων της vinca

Info

Publication number
CY1111476T1
CY1111476T1 CY20101100917T CY101100917T CY1111476T1 CY 1111476 T1 CY1111476 T1 CY 1111476T1 CY 20101100917 T CY20101100917 T CY 20101100917T CY 101100917 T CY101100917 T CY 101100917T CY 1111476 T1 CY1111476 T1 CY 1111476T1
Authority
CY
Cyprus
Prior art keywords
halogonated
mitotic
derivatives
vinca alkaloids
vinca
Prior art date
Application number
CY20101100917T
Other languages
English (en)
Inventor
Alain Duflos
Jacques Fahy
Valerie Thillaye Du Boullay
Jean-Marc Barret
Bridget Hill
Original Assignee
Pierre Fabre Medicament Production
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre Medicament Production filed Critical Pierre Fabre Medicament Production
Publication of CY1111476T1 publication Critical patent/CY1111476T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

H παρούσα εφεύρεση αφορά τη διτρυγική βινφλουνίνη και τη χρήση της σαν φάρμακο.
CY20101100917T 1997-04-10 2010-10-14 Αλογονωμενα αντι-μιτωτικα παραγωγα των αλκαλοειδων της vinca CY1111476T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9704398A FR2761990B1 (fr) 1997-04-10 1997-04-10 Derives halogenes antimitotiques d'alcaloides de vinca
EP20030017052 EP1357125A3 (fr) 1997-04-10 1998-04-10 Procédé de préparation de dérivés halogénés d'alcaloides de vinca
EP98920607A EP0975640B1 (fr) 1997-04-10 1998-04-10 Derives halogenes antimitotiques d'alcaloides de vinca

Publications (1)

Publication Number Publication Date
CY1111476T1 true CY1111476T1 (el) 2012-01-25

Family

ID=9505731

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20101100917T CY1111476T1 (el) 1997-04-10 2010-10-14 Αλογονωμενα αντι-μιτωτικα παραγωγα των αλκαλοειδων της vinca
CY2010019C CY2010019I1 (el) 1997-04-10 2010-12-22 Αλογονωμενα αντι-μιτωτικα παραγωγα των αλκαλοειδων της vinca

Family Applications After (1)

Application Number Title Priority Date Filing Date
CY2010019C CY2010019I1 (el) 1997-04-10 2010-12-22 Αλογονωμενα αντι-μιτωτικα παραγωγα των αλκαλοειδων της vinca

Country Status (15)

Country Link
US (1) US6127377A (el)
EP (3) EP1764368B1 (el)
JP (3) JP4401440B2 (el)
AT (2) ATE270297T1 (el)
AU (1) AU737549C (el)
BR (2) BR9807944B1 (el)
CA (3) CA2286560C (el)
CY (2) CY1111476T1 (el)
DE (3) DE122010000054I1 (el)
DK (2) DK1764368T3 (el)
ES (2) ES2347878T3 (el)
FR (2) FR2761990B1 (el)
LU (1) LU91769I2 (el)
PT (2) PT975640E (el)
WO (1) WO1998045301A1 (el)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2761990B1 (fr) * 1997-04-10 1999-06-25 Pf Medicament Derives halogenes antimitotiques d'alcaloides de vinca
US6890558B2 (en) * 2002-05-31 2005-05-10 R.P. Scherer Technologies, Inc. Oral pharmaceutical composition for soft capsules containing vinorelbine and method of treatment
WO2005055939A2 (en) * 2003-12-04 2005-06-23 Amr Technology, Inc. Vinca derivatives
US7235564B2 (en) * 2003-12-04 2007-06-26 Amr Technology, Inc. Vinorelbine derivatives
US20110015221A1 (en) * 2003-12-23 2011-01-20 Pierre Fabre Medicament Pharmaceutical composition of vinflunine which is intended for parenteral administration preparation method thereof and use of same
FR2863891B1 (fr) * 2003-12-23 2006-03-24 Pf Medicament Composition pharmaceutique de vinflunine destinee a une administration parentale, procede de preparation et utilisation
US7772177B2 (en) 2005-05-18 2010-08-10 Aegera Therapeutics, Inc. BIR domain binding compounds
FR2894966B1 (fr) * 2005-12-20 2008-03-14 Pierre Fabre Medicament Sa Nouvelle forme cristalline de la vinflunine
AU2007250443B2 (en) 2006-05-16 2013-06-13 Pharmascience Inc. IAP BIR domain binding compounds
WO2008033935A2 (en) * 2006-09-12 2008-03-20 Amr Technology, Inc. Vinorelbine derivatives
WO2008033930A2 (en) * 2006-09-12 2008-03-20 Amr Technology, Inc. Vinca derivatives
FR2905949B1 (fr) 2006-09-20 2008-11-21 Pierre Fabre Medicament Sa Derives fluores de catharanthine, leur preparation et leur utilisation comme precurseurs d'alcaloides dimeres de vinca
FR2910812B1 (fr) 2006-12-29 2009-03-20 Pierre Fabre Medicament Sa Compositions pharmaceutiques injectables lyophilisees de derives hemi-synthetiques d'alcaloide de vinca stables a temperature ambiante
FR2912406B1 (fr) * 2007-02-13 2009-05-08 Pierre Fabre Medicament Sa Sels cristalins anhydres de vinflunine, procede de preparation et utilisation en tant que medicament et moyen de purification de la vinflunine.
FR2918566B1 (fr) * 2007-07-11 2009-10-09 Pierre Fabre Medicament Sa Composition pharmaceutique stable d'un sel hydrosoluble de vinflunine.
FR2918567B1 (fr) * 2007-07-11 2012-08-03 Pf Medicament Composition pharmaceutique stable d'un sel hydrosoluble de vinorelbine.
US20090076055A1 (en) * 2007-09-14 2009-03-19 Protia, Llc Deuterium-enriched vinflunine
DE102010020994B4 (de) * 2010-01-27 2022-01-27 Interpane Entwicklungs-Und Beratungsgesellschaft Mbh Verfahren zur Herstellung eines beschichteten Gegenstands mit Texturätzen
NZ602368A (en) 2010-02-12 2014-10-31 Pharmascience Inc Iap bir domain binding compounds
JP5542972B2 (ja) * 2010-02-22 2014-07-09 ザ スクリプス リサーチ インスティテュート Ｍｄｒがん細胞に対する強化された生物活性を提供する１０’−フッ素化ビンカアルカロイド

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2707988B1 (fr) * 1993-07-21 1995-10-13 Pf Medicament Nouveaux dérivés antimitotiques des alcaloïdes binaires du catharantus rosesus, leur procédé de préparation et les compositions pharmaceutiques les comprenant.
FR2761990B1 (fr) * 1997-04-10 1999-06-25 Pf Medicament Derives halogenes antimitotiques d'alcaloides de vinca

Also Published As

Publication number Publication date
CA2455416C (fr) 2010-11-02
CA2455416A1 (fr) 1998-10-15
CA2286560C (fr) 2009-09-08
EP1357125A3 (fr) 2003-11-26
BR9816177B1 (pt) 2010-08-24
EP1357125A2 (fr) 2003-10-29
LU91769I2 (fr) 2011-02-22
FR10C0045I2 (fr) 2011-04-29
ES2222588T3 (es) 2005-02-01
EP1764368B1 (fr) 2010-07-14
DE69841766D1 (de) 2010-08-26
JP4401440B2 (ja) 2010-01-20
CY2010019I2 (el) 2012-01-25
DE122010000054I1 (de) 2011-05-05
AU737549C (en) 2002-03-28
EP0975640A1 (fr) 2000-02-02
BR9807944B1 (pt) 2011-02-08
CA2665949A1 (fr) 1998-10-15
WO1998045301A1 (fr) 1998-10-15
US6127377A (en) 2000-10-03
DE69824840D1 (de) 2004-08-05
ATE473987T1 (de) 2010-07-15
AU7340898A (en) 1998-10-30
DE69824840T2 (de) 2005-07-21
PT1764368E (pt) 2010-09-16
JP2001518892A (ja) 2001-10-16
JP2004277418A (ja) 2004-10-07
FR2761990B1 (fr) 1999-06-25
PT975640E (pt) 2004-11-30
JP4307292B2 (ja) 2009-08-05
JP2009167196A (ja) 2009-07-30
ES2347878T3 (es) 2010-11-22
CA2286560A1 (fr) 1998-10-15
CY2010019I1 (el) 2012-01-25
BR9807944A (pt) 2000-03-08
AU737549B2 (en) 2001-08-23
FR10C0045I1 (el) 2010-10-29
FR2761990A1 (fr) 1998-10-16
EP0975640B1 (fr) 2004-06-30
DK1764368T3 (da) 2010-10-18
CA2665949C (fr) 2013-06-11
DK0975640T3 (da) 2004-11-01
EP1764368A1 (fr) 2007-03-21
ATE270297T1 (de) 2004-07-15

Similar Documents

Publication Publication Date Title
CY1111476T1 (el) Αλογονωμενα αντι-μιτωτικα παραγωγα των αλκαλοειδων της vinca
DK1413582T3 (da) Dimere pyrrolobenzodiazepiner
DE3673114D1 (de) Zerstaeuber und dessen dochtanordnung.
EP0620251A3 (en) Miscible polyolefin blends.
FI952746A7 (fi) Polymeeriin sitoutuneen kamptotesiinijohdannaiset
DE69423626D1 (de) Gaserzeugende rückstandsfreie azidfreie zusammensetzung
SV1997000079A (es) Dihidrato d de olancepina ref. x- 11062t
BR9711586A (pt) Compostos e uso dos mesmo
FI955336L (fi) Varjoaineina käytettäviä trisyklopolyatsamakrosyklofosfonihappoja, niiden komplekseja ja johdannaisia
NO20001926L (no) Iso-CBI- og iso-CI-analoger av CC-1065 og duocarmycinene
FI961418A0 (fi) Atsolijohdannainen ja sen farmaseuttinen seos
MX9203099A (es) N-heterociclico-n-(4-piperidia)amidas y composiciones farmaceuticas y metodos que emplean dichos compuestos.
GR1000118B (el) Συνθεσις 1,2-διοξετανων & ενδιαμεσαι ουσιαι δι αυτην.
DE59402047D1 (de) Airbag-Gehäuse und dessen Befestigung
ES2157992T3 (es) Alcoxi-alquil-carbamatos de imidazo(1,2-a)piridinas.
FI943108L (fi) Orgaanisia happoja sisältävän jakeen käyttö
FR2686425B1 (fr) Source sismique de puits.
FI931000A7 (fi) Hajoavat polyamidit
FI943081L (fi) Bisykliset beta-laktaami/parabeenikompleksit
ES2181787T3 (es) Derivados de la 3h-2,3-benzodiazepina sustituidos en posicion 3, y su su utilizacion como medicamentos
DE3869116D1 (de) Spiro(bis)indan-bis-oxyphthalsaeuren und ihre funktionellen derivate.
ATE27599T1 (de) Rooperol und dessen derivate.
FI954422A0 (fi) Ferroseenin käyttö
ATE270551T1 (de) Kombinationspräparat aus 2-methylthiazolidin-2,4- dicarbonsäure und paracetamol
ES2165020T3 (es) Monohidrato de famciclovir.