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FR2918567B1 - Composition pharmaceutique stable d'un sel hydrosoluble de vinorelbine. - Google Patents

Composition pharmaceutique stable d'un sel hydrosoluble de vinorelbine.

Info

Publication number
FR2918567B1
FR2918567B1 FR0756425A FR0756425A FR2918567B1 FR 2918567 B1 FR2918567 B1 FR 2918567B1 FR 0756425 A FR0756425 A FR 0756425A FR 0756425 A FR0756425 A FR 0756425A FR 2918567 B1 FR2918567 B1 FR 2918567B1
Authority
FR
France
Prior art keywords
vinorelbine
pharmaceutical composition
water soluble
soluble salt
stable pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR0756425A
Other languages
English (en)
Other versions
FR2918567A1 (fr
Inventor
Bruno Paillard
Jean Louis Avan
Joel Bougaret
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Priority to FR0756425A priority Critical patent/FR2918567B1/fr
Priority to TW097125672A priority patent/TW200914017A/zh
Priority to TR2019/09405T priority patent/TR201909405T4/tr
Priority to ES08786003T priority patent/ES2733113T3/es
Priority to US12/668,372 priority patent/US20100196465A1/en
Priority to AU2008274224A priority patent/AU2008274224A1/en
Priority to KR1020107001419A priority patent/KR20100045439A/ko
Priority to CN200880024035A priority patent/CN101730534A/zh
Priority to NZ583039A priority patent/NZ583039A/en
Priority to CA2695040A priority patent/CA2695040A1/fr
Priority to HUE08786003 priority patent/HUE044165T2/hu
Priority to EP08786003.7A priority patent/EP2175855B1/fr
Priority to PL08786003T priority patent/PL2175855T3/pl
Priority to PCT/EP2008/058896 priority patent/WO2009007389A1/fr
Priority to BRPI0814224-6A2A priority patent/BRPI0814224A2/pt
Priority to DK08786003.7T priority patent/DK2175855T3/da
Priority to JP2010515501A priority patent/JP5774308B2/ja
Priority to RU2010103935/15A priority patent/RU2476208C2/ru
Priority to ARP080102966A priority patent/AR067498A1/es
Publication of FR2918567A1 publication Critical patent/FR2918567A1/fr
Priority to TNP2010000012A priority patent/TN2010000012A1/fr
Priority to ZA201000337A priority patent/ZA201000337B/xx
Priority to MA32551A priority patent/MA31541B1/fr
Application granted granted Critical
Publication of FR2918567B1 publication Critical patent/FR2918567B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR0756425A 2007-07-11 2007-07-11 Composition pharmaceutique stable d'un sel hydrosoluble de vinorelbine. Active FR2918567B1 (fr)

Priority Applications (22)

Application Number Priority Date Filing Date Title
FR0756425A FR2918567B1 (fr) 2007-07-11 2007-07-11 Composition pharmaceutique stable d'un sel hydrosoluble de vinorelbine.
TW097125672A TW200914017A (en) 2007-07-11 2008-07-08 Stable pharmaceutical composition of a water-soluble vinorelbine salt
DK08786003.7T DK2175855T3 (da) 2007-07-11 2008-07-09 Stabil farmaceutisk sammensætning af et vandopløseligt vinorelbin-salt
US12/668,372 US20100196465A1 (en) 2007-07-11 2008-07-09 Stable pharmaceutical composition of a water-soluble vinorelbine salt
AU2008274224A AU2008274224A1 (en) 2007-07-11 2008-07-09 Stable pharmaceutical composition of a water-soluble vinorelbine salt
KR1020107001419A KR20100045439A (ko) 2007-07-11 2008-07-09 수용성 빈노렐빈 염의 안정적인 약학적 조성물
CN200880024035A CN101730534A (zh) 2007-07-11 2008-07-09 包含水溶性长春瑞滨盐的稳定的药物组合物
NZ583039A NZ583039A (en) 2007-07-11 2008-07-09 Stable pharmaceutical composition of a water-soluble vinorelbine salt
CA2695040A CA2695040A1 (fr) 2007-07-11 2008-07-09 Composition pharmaceutique stable d'un sel de vinorelbine soluble dans l'eau
HUE08786003 HUE044165T2 (hu) 2007-07-11 2008-07-09 Vízoldékony vinorelbin-só stabil gyógyszerészeti készítménye
EP08786003.7A EP2175855B1 (fr) 2007-07-11 2008-07-09 Composition pharmaceutique stable d'un sel de vinorelbine soluble dans l'eau
PL08786003T PL2175855T3 (pl) 2007-07-11 2008-07-09 Stabilna kompozycja farmaceutyczna soli winorelbiny rozpuszczalnej w wodzie
TR2019/09405T TR201909405T4 (tr) 2007-07-11 2008-07-09 Suda çözünebi̇li̇r vi̇norelbi̇n tuzunun stabi̇l farmasöti̇k bi̇leşi̇mi̇
BRPI0814224-6A2A BRPI0814224A2 (pt) 2007-07-11 2008-07-09 Composição farmacêutica estável de um sal de vinorrelbina solúvel em água
ES08786003T ES2733113T3 (es) 2007-07-11 2008-07-09 Composición farmacéutica estable de una sal de vinorelbina soluble en agua
JP2010515501A JP5774308B2 (ja) 2007-07-11 2008-07-09 水溶性ビノレルビン塩の安定な医薬組成物
RU2010103935/15A RU2476208C2 (ru) 2007-07-11 2008-07-09 Стабильная фармацевтическая композиция водорастворимой соли винорелбина
PCT/EP2008/058896 WO2009007389A1 (fr) 2007-07-11 2008-07-09 Composition pharmaceutique stable d'un sel de vinorelbine soluble dans l'eau
ARP080102966A AR067498A1 (es) 2007-07-11 2008-07-10 Composicion farmaceutica estable de una sal hidrosoluble de vinorrelbina
TNP2010000012A TN2010000012A1 (en) 2007-07-11 2010-01-08 Stable pharmaceutical composition of a water soluble vinorelbine salt
ZA201000337A ZA201000337B (en) 2007-07-11 2010-01-18 Stable pharmaceutical composition of a water-soluble vinorelbine salt
MA32551A MA31541B1 (fr) 2007-07-11 2010-01-25 Composition pharmaceutique stable d'un sel hydrosoluble de vinorelbine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0756425A FR2918567B1 (fr) 2007-07-11 2007-07-11 Composition pharmaceutique stable d'un sel hydrosoluble de vinorelbine.

Publications (2)

Publication Number Publication Date
FR2918567A1 FR2918567A1 (fr) 2009-01-16
FR2918567B1 true FR2918567B1 (fr) 2012-08-03

Family

ID=38846787

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0756425A Active FR2918567B1 (fr) 2007-07-11 2007-07-11 Composition pharmaceutique stable d'un sel hydrosoluble de vinorelbine.

Country Status (22)

Country Link
US (1) US20100196465A1 (fr)
EP (1) EP2175855B1 (fr)
JP (1) JP5774308B2 (fr)
KR (1) KR20100045439A (fr)
CN (1) CN101730534A (fr)
AR (1) AR067498A1 (fr)
AU (1) AU2008274224A1 (fr)
BR (1) BRPI0814224A2 (fr)
CA (1) CA2695040A1 (fr)
DK (1) DK2175855T3 (fr)
ES (1) ES2733113T3 (fr)
FR (1) FR2918567B1 (fr)
HU (1) HUE044165T2 (fr)
MA (1) MA31541B1 (fr)
NZ (1) NZ583039A (fr)
PL (1) PL2175855T3 (fr)
RU (1) RU2476208C2 (fr)
TN (1) TN2010000012A1 (fr)
TR (1) TR201909405T4 (fr)
TW (1) TW200914017A (fr)
WO (1) WO2009007389A1 (fr)
ZA (1) ZA201000337B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105267179B (zh) * 2014-07-08 2020-04-03 东曜药业有限公司 包含水溶性长春瑞滨盐的稳定的固体药物组合物及其制备方法
RU2730521C2 (ru) * 2016-03-09 2020-08-24 Синбиас Фарма АГ Винорелбина монотартрат и его фармацевтическое применение

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3879541A (en) * 1970-03-03 1975-04-22 Bayer Ag Antihyperglycemic methods and compositions
US4551177A (en) * 1984-04-23 1985-11-05 National Starch And Chemical Corporation Compressible starches as binders for tablets or capsules
FR2707988B1 (fr) * 1993-07-21 1995-10-13 Pf Medicament Nouveaux dérivés antimitotiques des alcaloïdes binaires du catharantus rosesus, leur procédé de préparation et les compositions pharmaceutiques les comprenant.
FR2759293B1 (fr) * 1997-02-11 1999-04-30 Ethypharm Lab Prod Ethiques Microgranules contenant du cisplatine, procede de fabrication, preparation pharmaceutique et utilisation en polychimiotherapie ou en association avec une radiotherapie
FR2761990B1 (fr) * 1997-04-10 1999-06-25 Pf Medicament Derives halogenes antimitotiques d'alcaloides de vinca
PL204921B1 (pl) * 1998-05-15 2010-02-26 Warner Lambert Co Stabilizowana kompozycja farmaceutyczna zawierająca 4-amino-3-podstawioną pochodną kwasu butanowego i α-aminokwas oraz sposób jej wytwarzania
US6242003B1 (en) * 2000-04-13 2001-06-05 Novartis Ag Organic compounds
CZ20002567A3 (cs) * 2000-07-11 2001-12-12 Léčiva, A.S. Tableta vyrobitelná přímým tabletováním, obsahující aktivní látku kyselinu 4-amino-1-hydroxybutyliden-1,1-bisfosfonovou, a způsob její výroby
BRPI0206432A2 (pt) * 2001-01-12 2016-10-25 Sun Pharmaceutical Ind Ltd métodos para administrar dois ou mais agentes terapêuticos ativos e para tratar diabetes melito ou sintomas associados com diabetes melito em um humano e sistema de liberação espaçada de medicamento
DE60330764D1 (de) * 2002-04-26 2010-02-11 Hoffmann La Roche Pharmazeutische zusammensetzung enthaltend einen lipase - inhibitor und glucomannan
JP2003321349A (ja) * 2002-05-08 2003-11-11 Capsugel Japan Inc イカスミ色素含有インクによる硬質カプセルへの印刷
PT1530459E (pt) * 2002-05-31 2010-05-20 Rp Scherer Technologies Llc Composição farmacêutica oral para cápsulas moles contendo vinorelbina e método de tratamento
US6890558B2 (en) * 2002-05-31 2005-05-10 R.P. Scherer Technologies, Inc. Oral pharmaceutical composition for soft capsules containing vinorelbine and method of treatment
US20030138430A1 (en) * 2002-09-20 2003-07-24 Stimmel Julie Beth Pharmaceutical comprising an agent that blocks the cell cycle and an antibody
DE10351448A1 (de) * 2003-11-04 2005-06-09 Bayer Healthcare Ag Geschmackstoffhaltige Arzneimittelformulierungen mit verbesserten pharmazeutischen Eigenschaften
FR2863891B1 (fr) * 2003-12-23 2006-03-24 Pf Medicament Composition pharmaceutique de vinflunine destinee a une administration parentale, procede de preparation et utilisation
US20060147518A1 (en) * 2004-12-30 2006-07-06 Pierre Fabre Medicament Stable solid dispersion of a derivative of vinca alkaloid and process for manufacturing it
BRPI0519466B8 (pt) * 2004-12-30 2021-05-25 Pf Medicament dispersão sólida estável de um derivado de alcalóide de vinca e processo para a fabricação do mesmo

Also Published As

Publication number Publication date
EP2175855A1 (fr) 2010-04-21
AU2008274224A1 (en) 2009-01-15
JP5774308B2 (ja) 2015-09-09
AR067498A1 (es) 2009-10-14
RU2010103935A (ru) 2011-08-20
WO2009007389A1 (fr) 2009-01-15
US20100196465A1 (en) 2010-08-05
CN101730534A (zh) 2010-06-09
TW200914017A (en) 2009-04-01
KR20100045439A (ko) 2010-05-03
DK2175855T3 (da) 2019-07-01
RU2476208C2 (ru) 2013-02-27
JP2010533140A (ja) 2010-10-21
PL2175855T3 (pl) 2019-10-31
HUE044165T2 (hu) 2019-10-28
EP2175855B1 (fr) 2019-04-10
TN2010000012A1 (en) 2011-09-26
MA31541B1 (fr) 2010-07-01
NZ583039A (en) 2012-06-29
ES2733113T3 (es) 2019-11-27
TR201909405T4 (tr) 2019-07-22
BRPI0814224A2 (pt) 2015-01-06
FR2918567A1 (fr) 2009-01-16
CA2695040A1 (fr) 2009-01-15
ZA201000337B (en) 2010-09-29

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