TN2010000012A1 - Stable pharmaceutical composition of a water soluble vinorelbine salt - Google Patents

Stable pharmaceutical composition of a water soluble vinorelbine salt

Info

Publication number: TN2010000012A1
Authority: TN; Tunisia
Prior art keywords: pharmaceutical composition; water soluble; stable pharmaceutical; salt; vinorelbine salt
Prior art date: 2007-07-11

Application number

TNP2010000012A

Other languages

English (en)

Inventor

Bruno Paillard

Jean Louis Avan

Joel Bougaret

Original Assignee

Pf Medicament

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-07-11

Filing date

2010-01-08

Publication date

2011-09-26

2010-01-08 Application filed by Pf Medicament filed Critical Pf Medicament

2011-09-26 Publication of TN2010000012A1 publication Critical patent/TN2010000012A1/fr

Links

239000008194 pharmaceutical composition Substances 0.000 title abstract 3
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title abstract 2
GBABOYUKABKIAF-GHYRFKGUSA-N vinorelbine Chemical class C1N(CC=2C3=CC=CC=C3NC=22)CC(CC)=C[C@H]1C[C@]2(C(=O)OC)C1=CC([C@]23[C@H]([C@]([C@H](OC(C)=O)[C@]4(CC)C=CCN([C@H]34)CC2)(O)C(=O)OC)N2C)=C2C=C1OC GBABOYUKABKIAF-GHYRFKGUSA-N 0.000 title 1
GBABOYUKABKIAF-IELIFDKJSA-N vinorelbine Chemical class C1N(CC=2C3=CC=CC=C3NC=22)CC(CC)=C[C@H]1C[C@]2(C(=O)OC)C1=CC([C@]23[C@H]([C@@]([C@H](OC(C)=O)[C@]4(CC)C=CCN([C@H]34)CC2)(O)C(=O)OC)N2C)=C2C=C1OC GBABOYUKABKIAF-IELIFDKJSA-N 0.000 abstract 2
239000003085 diluting agent Substances 0.000 abstract 1
239000007903 gelatin capsule Substances 0.000 abstract 1
239000000314 lubricant Substances 0.000 abstract 1
239000007787 solid Substances 0.000 abstract 1
229960002066 vinorelbine Drugs 0.000 abstract 1
CILBMBUYJCWATM-HGBQGYOLSA-N vinorelbine D-tartrate Chemical compound OC(=O)[C@@H](O)[C@H](O)C(O)=O.OC(=O)[C@@H](O)[C@H](O)C(O)=O.C1N(CC=2C3=CC=CC=C3NC=22)CC(CC)=C[C@H]1C[C@]2(C(=O)OC)C1=CC([C@]23[C@H]([C@]([C@H](OC(C)=O)[C@]4(CC)C=CCN([C@H]34)CC2)(O)C(=O)OC)N2C)=C2C=C1OC CILBMBUYJCWATM-HGBQGYOLSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

TNP2010000012A 2007-07-11 2010-01-08 Stable pharmaceutical composition of a water soluble vinorelbine salt TN2010000012A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0756425A FR2918567B1 (fr)	2007-07-11	2007-07-11	Composition pharmaceutique stable d'un sel hydrosoluble de vinorelbine.
PCT/EP2008/058896 WO2009007389A1 (fr)	2007-07-11	2008-07-09	Composition pharmaceutique stable d'un sel de vinorelbine soluble dans l'eau

Publications (1)

Publication Number	Publication Date
TN2010000012A1 true TN2010000012A1 (en)	2011-09-26

Family

ID=38846787

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TNP2010000012A TN2010000012A1 (en)	2007-07-11	2010-01-08	Stable pharmaceutical composition of a water soluble vinorelbine salt

Country Status (22)

Country	Link
US (1)	US20100196465A1 (fr)
EP (1)	EP2175855B1 (fr)
JP (1)	JP5774308B2 (fr)
KR (1)	KR20100045439A (fr)
CN (1)	CN101730534A (fr)
AR (1)	AR067498A1 (fr)
AU (1)	AU2008274224A1 (fr)
BR (1)	BRPI0814224A2 (fr)
CA (1)	CA2695040A1 (fr)
DK (1)	DK2175855T3 (fr)
ES (1)	ES2733113T3 (fr)
FR (1)	FR2918567B1 (fr)
HU (1)	HUE044165T2 (fr)
MA (1)	MA31541B1 (fr)
NZ (1)	NZ583039A (fr)
PL (1)	PL2175855T3 (fr)
RU (1)	RU2476208C2 (fr)
TN (1)	TN2010000012A1 (fr)
TR (1)	TR201909405T4 (fr)
TW (1)	TW200914017A (fr)
WO (1)	WO2009007389A1 (fr)
ZA (1)	ZA201000337B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN105267179B (zh) *	2014-07-08	2020-04-03	东曜药业有限公司	包含水溶性长春瑞滨盐的稳定的固体药物组合物及其制备方法
CN108779129A (zh) *	2016-03-09	2018-11-09	赛比亚斯药业股份公司	长春瑞滨单酒石酸盐及其药物用途

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3879541A (en) *	1970-03-03	1975-04-22	Bayer Ag	Antihyperglycemic methods and compositions
US4551177A (en) *	1984-04-23	1985-11-05	National Starch And Chemical Corporation	Compressible starches as binders for tablets or capsules
FR2707988B1 (fr) *	1993-07-21	1995-10-13	Pf Medicament	Nouveaux dérivés antimitotiques des alcaloïdes binaires du catharantus rosesus, leur procédé de préparation et les compositions pharmaceutiques les comprenant.
FR2759293B1 (fr) *	1997-02-11	1999-04-30	Ethypharm Lab Prod Ethiques	Microgranules contenant du cisplatine, procede de fabrication, preparation pharmaceutique et utilisation en polychimiotherapie ou en association avec une radiotherapie
FR2761990B1 (fr) *	1997-04-10	1999-06-25	Pf Medicament	Derives halogenes antimitotiques d'alcaloides de vinca
CN1303991C (zh) *	1998-05-15	2007-03-14	沃尼尔·朗伯公司	γ－氨基丁酸衍生物的稳定药物制剂和其制备方法
US6242003B1 (en) *	2000-04-13	2001-06-05	Novartis Ag	Organic compounds
CZ20002567A3 (cs) *	2000-07-11	2001-12-12	Léčiva, A.S.	Tableta vyrobitelná přímým tabletováním, obsahující aktivní látku kyselinu 4-amino-1-hydroxybutyliden-1,1-bisfosfonovou, a způsob její výroby
CA2725833A1 (fr) *	2001-01-12	2002-07-18	Sun Pharmaceutical Industries Limited	Systeme de liberation espacee de medicaments
DE60330764D1 (de) *	2002-04-26	2010-02-11	Hoffmann La Roche	Pharmazeutische zusammensetzung enthaltend einen lipase - inhibitor und glucomannan
JP2003321349A (ja) *	2002-05-08	2003-11-11	Capsugel Japan Inc	イカスミ色素含有インクによる硬質カプセルへの印刷
US6890558B2 (en) *	2002-05-31	2005-05-10	R.P. Scherer Technologies, Inc.	Oral pharmaceutical composition for soft capsules containing vinorelbine and method of treatment
AU2003240808B2 (en) *	2002-05-31	2008-05-08	R. P. Scherer Technologies, Inc.	Oral pharmaceutical composition for soft capsules containing vinorelbine and method of treatment
US20030138430A1 (en) *	2002-09-20	2003-07-24	Stimmel Julie Beth	Pharmaceutical comprising an agent that blocks the cell cycle and an antibody
DE10351448A1 (de) *	2003-11-04	2005-06-09	Bayer Healthcare Ag	Geschmackstoffhaltige Arzneimittelformulierungen mit verbesserten pharmazeutischen Eigenschaften
FR2863891B1 (fr) *	2003-12-23	2006-03-24	Pf Medicament	Composition pharmaceutique de vinflunine destinee a une administration parentale, procede de preparation et utilisation
US20060147518A1 (en) *	2004-12-30	2006-07-06	Pierre Fabre Medicament	Stable solid dispersion of a derivative of vinca alkaloid and process for manufacturing it
WO2006069938A1 (fr) *	2004-12-30	2006-07-06	Pierre Fabre Medicament	Suspension solide stable d'un dérivé de vinca-alcaloïde et procédé de fabrication dudit dérivé

2007
- 2007-07-11 FR FR0756425A patent/FR2918567B1/fr active Active
2008
- 2008-07-08 TW TW097125672A patent/TW200914017A/zh unknown
- 2008-07-09 CA CA2695040A patent/CA2695040A1/fr not_active Abandoned
- 2008-07-09 ES ES08786003T patent/ES2733113T3/es active Active
- 2008-07-09 HU HUE08786003 patent/HUE044165T2/hu unknown
- 2008-07-09 WO PCT/EP2008/058896 patent/WO2009007389A1/fr not_active Ceased
- 2008-07-09 CN CN200880024035A patent/CN101730534A/zh active Pending
- 2008-07-09 EP EP08786003.7A patent/EP2175855B1/fr active Active
- 2008-07-09 TR TR2019/09405T patent/TR201909405T4/tr unknown
- 2008-07-09 BR BRPI0814224-6A2A patent/BRPI0814224A2/pt not_active IP Right Cessation
- 2008-07-09 DK DK08786003.7T patent/DK2175855T3/da active
- 2008-07-09 AU AU2008274224A patent/AU2008274224A1/en not_active Abandoned
- 2008-07-09 PL PL08786003T patent/PL2175855T3/pl unknown
- 2008-07-09 JP JP2010515501A patent/JP5774308B2/ja active Active
- 2008-07-09 RU RU2010103935/15A patent/RU2476208C2/ru not_active IP Right Cessation
- 2008-07-09 NZ NZ583039A patent/NZ583039A/en not_active IP Right Cessation
- 2008-07-09 KR KR1020107001419A patent/KR20100045439A/ko not_active Ceased
- 2008-07-09 US US12/668,372 patent/US20100196465A1/en not_active Abandoned
- 2008-07-10 AR ARP080102966A patent/AR067498A1/es not_active Application Discontinuation
2010
- 2010-01-08 TN TNP2010000012A patent/TN2010000012A1/fr unknown
- 2010-01-18 ZA ZA201000337A patent/ZA201000337B/xx unknown
- 2010-01-25 MA MA32551A patent/MA31541B1/fr unknown

Also Published As

Publication number	Publication date
TR201909405T4 (tr)	2019-07-22
ZA201000337B (en)	2010-09-29
RU2476208C2 (ru)	2013-02-27
HUE044165T2 (hu)	2019-10-28
AR067498A1 (es)	2009-10-14
NZ583039A (en)	2012-06-29
MA31541B1 (fr)	2010-07-01
JP5774308B2 (ja)	2015-09-09
AU2008274224A1 (en)	2009-01-15
ES2733113T3 (es)	2019-11-27
TW200914017A (en)	2009-04-01
PL2175855T3 (pl)	2019-10-31
JP2010533140A (ja)	2010-10-21
EP2175855B1 (fr)	2019-04-10
CN101730534A (zh)	2010-06-09
EP2175855A1 (fr)	2010-04-21
CA2695040A1 (fr)	2009-01-15
WO2009007389A1 (fr)	2009-01-15
BRPI0814224A2 (pt)	2015-01-06
FR2918567B1 (fr)	2012-08-03
RU2010103935A (ru)	2011-08-20
KR20100045439A (ko)	2010-05-03
US20100196465A1 (en)	2010-08-05
DK2175855T3 (da)	2019-07-01
FR2918567A1 (fr)	2009-01-16

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