CY1110448T1 - Ενωσεις ριλουζολης και λεβαντοπας για τη θεραπεια της ασθενειας του παρκινσον - Google Patents
Ενωσεις ριλουζολης και λεβαντοπας για τη θεραπεια της ασθενειας του παρκινσονInfo
- Publication number
- CY1110448T1 CY1110448T1 CY20081100457T CY081100457T CY1110448T1 CY 1110448 T1 CY1110448 T1 CY 1110448T1 CY 20081100457 T CY20081100457 T CY 20081100457T CY 081100457 T CY081100457 T CY 081100457T CY 1110448 T1 CY1110448 T1 CY 1110448T1
- Authority
- CY
- Cyprus
- Prior art keywords
- rilozolis
- lavandopas
- units
- treatment
- disease
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- WTDRDQBEARUVNC-LURJTMIESA-N L-DOPA Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-LURJTMIESA-N 0.000 abstract 1
- WTDRDQBEARUVNC-UHFFFAOYSA-N L-Dopa Natural products OC(=O)C(N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-UHFFFAOYSA-N 0.000 abstract 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- FTALBRSUTCGOEG-UHFFFAOYSA-N Riluzole Chemical compound C1=C(OC(F)(F)F)C=C2SC(N)=NC2=C1 FTALBRSUTCGOEG-UHFFFAOYSA-N 0.000 abstract 1
- 229960004502 levodopa Drugs 0.000 abstract 1
- 229960004181 riluzole Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- External Artificial Organs (AREA)
Abstract
Ένωση της λεβοντόπας και της ριλουζόλης ή ενός φαρμακευτικά αποδεκτού άλατος αυτής της ένωσης και χρήση αυτής της ένωσης για τη θεραπεία της νόσου του Πάρκινσον.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9805153A FR2777781B1 (fr) | 1998-04-24 | 1998-04-24 | Associations riluzole et l-dopa pour le traitement de la maladie de parkinson |
| EP99915809A EP1071422B1 (fr) | 1998-04-24 | 1999-04-22 | Associations de riluzole et de levodopa pour le traitement de la maladie de parkinson |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1110448T1 true CY1110448T1 (el) | 2015-04-29 |
Family
ID=9525640
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20081100457T CY1110448T1 (el) | 1998-04-24 | 2008-04-24 | Ενωσεις ριλουζολης και λεβαντοπας για τη θεραπεια της ασθενειας του παρκινσον |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6387936B1 (el) |
| EP (1) | EP1071422B1 (el) |
| JP (1) | JP2002512963A (el) |
| KR (1) | KR100597170B1 (el) |
| AT (1) | ATE386520T1 (el) |
| AU (1) | AU768069B2 (el) |
| CA (1) | CA2329636C (el) |
| CY (1) | CY1110448T1 (el) |
| CZ (1) | CZ300825B6 (el) |
| DE (1) | DE69938179T2 (el) |
| DK (1) | DK1071422T3 (el) |
| ES (1) | ES2300141T3 (el) |
| FR (1) | FR2777781B1 (el) |
| HU (1) | HU228902B1 (el) |
| IL (1) | IL139164A (el) |
| NO (1) | NO329032B1 (el) |
| PT (1) | PT1071422E (el) |
| RU (1) | RU2225204C2 (el) |
| SK (1) | SK285531B6 (el) |
| UA (1) | UA70319C2 (el) |
| WO (1) | WO1999055336A1 (el) |
| ZA (1) | ZA200005758B (el) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2786101B1 (fr) * | 1998-11-24 | 2002-07-05 | Aventis Laboratoire | Utilisation de la nicergoline dans le traitement de la spasticite |
| US6872739B1 (en) * | 1999-06-04 | 2005-03-29 | Vereniging Voor Christelijk Wetenshappelikjk Onderwijs | Use of riluzole for the treatment of multiple sclerosis |
| GB0007193D0 (en) * | 2000-03-25 | 2000-05-17 | Univ Manchester | Treatment of movrmrnt disorders |
| US20060105036A1 (en) | 2003-05-12 | 2006-05-18 | Stephen Peroutka | Threo-dops controlled release formulation |
| US8158149B2 (en) * | 2004-05-12 | 2012-04-17 | Chelsea Therapeutics, Inc. | Threo-DOPS controlled release formulation |
| WO2005025561A1 (en) * | 2003-09-04 | 2005-03-24 | Synergia Pharma, Inc. | Compositions and methods for orthostatic intolerance |
| EP1751312A4 (en) * | 2004-05-21 | 2010-01-27 | Univ Duke | POLYMORPHISM IN TRYPTOPHAN HYDROXYLASE 2 REGULATING BRAIN SEROTONIN SYNTHESIS |
| SE0401842D0 (sv) | 2004-07-12 | 2004-07-12 | Dizlin Medical Design Ab | Infusion and injection solution of levodopa |
| WO2006060120A2 (en) * | 2004-11-07 | 2006-06-08 | Guilford F Timothy | Liposomal formulation for oral administration of glutathione (reduced) |
| GB0504103D0 (en) * | 2005-02-28 | 2005-04-06 | Syngenta Ltd | Novel method |
| CA2613631A1 (en) * | 2005-06-23 | 2007-01-04 | Spherics, Inc. | Improved dosage forms for movement disorder treatment |
| US20080131492A1 (en) * | 2006-06-23 | 2008-06-05 | Spherics, Inc. | Dosage forms for movement disorder treatment |
| PL1948155T3 (pl) * | 2006-06-28 | 2012-10-31 | Chelsea Therapeutics Inc | Kompozycje farmaceutyczne zawierające droksidopę |
| WO2008079404A2 (en) * | 2006-12-22 | 2008-07-03 | Combinatorx, Incorporated | Pharmaceutical compositions for treatment of parkinson's disease and related disorders |
| EP2468271B1 (en) * | 2007-03-09 | 2014-07-16 | Chelsea Therapeutics, Inc. | Pharmaceutical composition comprising droxidopa for the treatment of fibromyalgia |
| EP2167066B1 (en) * | 2007-05-07 | 2013-06-26 | Chelsea Therapeutics, Inc. | Droxidopa and pharmaceutical composition thereof for the treatment of attention deficit disorders |
| BRPI0913642A2 (pt) * | 2008-06-30 | 2015-11-24 | Novartis Ag | produtos de combinação |
| BRPI0921431A2 (pt) * | 2008-11-06 | 2017-06-06 | Biotie Therapies Ag | método para tratar ou prevenir síndrome das pernas inquietas, composição farmacêutica, e, métodos para tratar ou prevenir distúrbios do sono, e para melhorar a quantidade do sono ou adequação do sono |
| EP2228054A1 (en) * | 2009-03-13 | 2010-09-15 | ITALFARMACO S.p.A. | Riluzole aqueous suspensions |
| ES2703255T3 (es) | 2010-10-22 | 2019-03-07 | Univ Duke | Formulaciones de liberación lenta de 5-hidroxitriptófano como un complemento para terapias pro-serotoninérgicas |
| JP5880913B2 (ja) | 2011-05-17 | 2016-03-09 | 三郎 佐古田 | パーキンソン病の体幹症状(姿勢反射異常)の治療剤 |
| WO2014172372A1 (en) | 2013-04-15 | 2014-10-23 | Northwestern University | Treatment for dopaminergic disorders |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2700117B1 (fr) * | 1993-01-07 | 1995-02-03 | Rhone Poulenc Rorer Sa | Application d'anticonvulsivants dans le traitement de la maladie de Parkinson et des syndromes parkinsoniens. |
| RU2057529C1 (ru) * | 1994-05-30 | 1996-04-10 | Алексей Михайлович Коршунов | Способ лечения синдрома паркинсонизма |
-
1998
- 1998-04-24 FR FR9805153A patent/FR2777781B1/fr not_active Expired - Fee Related
-
1999
- 1999-04-22 HU HU0101645A patent/HU228902B1/hu not_active IP Right Cessation
- 1999-04-22 CA CA002329636A patent/CA2329636C/fr not_active Expired - Fee Related
- 1999-04-22 UA UA2000105983A patent/UA70319C2/uk unknown
- 1999-04-22 AU AU34255/99A patent/AU768069B2/en not_active Ceased
- 1999-04-22 JP JP2000545534A patent/JP2002512963A/ja not_active Withdrawn
- 1999-04-22 DE DE69938179T patent/DE69938179T2/de not_active Expired - Lifetime
- 1999-04-22 CZ CZ20003908A patent/CZ300825B6/cs not_active IP Right Cessation
- 1999-04-22 ES ES99915809T patent/ES2300141T3/es not_active Expired - Lifetime
- 1999-04-22 EP EP99915809A patent/EP1071422B1/fr not_active Expired - Lifetime
- 1999-04-22 KR KR1020007011786A patent/KR100597170B1/ko not_active Expired - Fee Related
- 1999-04-22 IL IL13916499A patent/IL139164A/xx not_active IP Right Cessation
- 1999-04-22 DK DK99915809T patent/DK1071422T3/da active
- 1999-04-22 AT AT99915809T patent/ATE386520T1/de active
- 1999-04-22 RU RU2000129121/15A patent/RU2225204C2/ru not_active IP Right Cessation
- 1999-04-22 WO PCT/FR1999/000953 patent/WO1999055336A1/fr not_active Ceased
- 1999-04-22 PT PT99915809T patent/PT1071422E/pt unknown
- 1999-04-22 SK SK1588-2000A patent/SK285531B6/sk not_active IP Right Cessation
-
2000
- 2000-10-17 ZA ZA200005758A patent/ZA200005758B/en unknown
- 2000-10-20 NO NO20005290A patent/NO329032B1/no not_active IP Right Cessation
- 2000-10-24 US US09/694,860 patent/US6387936B1/en not_active Expired - Lifetime
-
2008
- 2008-04-24 CY CY20081100457T patent/CY1110448T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2002512963A (ja) | 2002-05-08 |
| NO329032B1 (no) | 2010-08-02 |
| DE69938179T2 (de) | 2009-02-12 |
| DK1071422T3 (da) | 2008-06-16 |
| HU228902B1 (en) | 2013-06-28 |
| ZA200005758B (en) | 2002-01-17 |
| FR2777781B1 (fr) | 2004-04-09 |
| NO20005290D0 (no) | 2000-10-20 |
| SK15882000A3 (sk) | 2001-04-09 |
| KR20010042960A (ko) | 2001-05-25 |
| ATE386520T1 (de) | 2008-03-15 |
| HUP0101645A3 (en) | 2002-10-28 |
| FR2777781A1 (fr) | 1999-10-29 |
| DE69938179D1 (de) | 2008-04-03 |
| CA2329636C (fr) | 2009-09-08 |
| EP1071422B1 (fr) | 2008-02-20 |
| SK285531B6 (sk) | 2007-03-01 |
| AU768069B2 (en) | 2003-12-04 |
| IL139164A (en) | 2005-12-18 |
| UA70319C2 (en) | 2004-10-15 |
| PT1071422E (pt) | 2008-05-05 |
| EP1071422A1 (fr) | 2001-01-31 |
| CZ20003908A3 (cs) | 2001-02-14 |
| KR100597170B1 (ko) | 2006-07-05 |
| CA2329636A1 (fr) | 1999-11-04 |
| AU3425599A (en) | 1999-11-16 |
| WO1999055336A1 (fr) | 1999-11-04 |
| NO20005290L (no) | 2000-10-20 |
| US6387936B1 (en) | 2002-05-14 |
| IL139164A0 (en) | 2001-11-25 |
| ES2300141T3 (es) | 2008-06-01 |
| HUP0101645A2 (hu) | 2001-09-28 |
| CZ300825B6 (cs) | 2009-08-19 |
| RU2225204C2 (ru) | 2004-03-10 |
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