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CL2009001267A1 - Compuestos derivados de triciclos nitrogenados, con actividad antibacteriana; procedimiento de preparacion; composicion farmceutica que los comprende; para el tratamiento de la tuberculosis. - Google Patents

Compuestos derivados de triciclos nitrogenados, con actividad antibacteriana; procedimiento de preparacion; composicion farmceutica que los comprende; para el tratamiento de la tuberculosis.

Info

Publication number
CL2009001267A1
CL2009001267A1 CL2009001267A CL2009001267A CL2009001267A1 CL 2009001267 A1 CL2009001267 A1 CL 2009001267A1 CL 2009001267 A CL2009001267 A CL 2009001267A CL 2009001267 A CL2009001267 A CL 2009001267A CL 2009001267 A1 CL2009001267 A1 CL 2009001267A1
Authority
CL
Chile
Prior art keywords
tuberculosis
tricycles
nitrogenous
treatment
pharmaceutical composition
Prior art date
Application number
CL2009001267A
Other languages
English (en)
Inventor
C Alemparte-Gallardo
C Barfoot
D Barros-Aguirre
M Cacho-Izquierdo
Roman J Fiandor
S Hennessy
N Pearson
Modesto Jesus Remmuinan-Blanco
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of CL2009001267A1 publication Critical patent/CL2009001267A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/16—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

COMPUESTOS DE FÓRMULA (I) O SALES O N-ÓXIDOS FARMACÉUTICAMENTE ACEPTABLES DE LOS MISMOS,<br /> DONDE Z1, Z2, U, R5, R6 Y N SE DEFINEN EN LA MEMORIA DESCRIPTIVA; COMPOSICIONES 'FARMACÉUTICAS QUE<br /> LOS COMPRENDEN, SU USO EN LA TERAPIA, ESPECIALMENTE CONTRA LA TUBERCULOSIS, Y PROCEDIMIENTO PARA PREPARARLOS.<br />  
CL2009001267A 2008-05-23 2009-05-22 Compuestos derivados de triciclos nitrogenados, con actividad antibacteriana; procedimiento de preparacion; composicion farmceutica que los comprende; para el tratamiento de la tuberculosis. CL2009001267A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08382018 2008-05-23
EP08382044 2008-10-17
EP08382057 2008-10-17

Publications (1)

Publication Number Publication Date
CL2009001267A1 true CL2009001267A1 (es) 2010-12-31

Family

ID=40874958

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2009001267A CL2009001267A1 (es) 2008-05-23 2009-05-22 Compuestos derivados de triciclos nitrogenados, con actividad antibacteriana; procedimiento de preparacion; composicion farmceutica que los comprende; para el tratamiento de la tuberculosis.

Country Status (24)

Country Link
US (1) US8097628B2 (es)
EP (1) EP2300476B1 (es)
JP (1) JP5474941B2 (es)
KR (1) KR20110016947A (es)
CN (1) CN102105473B (es)
AR (1) AR071869A1 (es)
AU (1) AU2009248786B2 (es)
BR (1) BRPI0912995A2 (es)
CA (1) CA2725726A1 (es)
CL (1) CL2009001267A1 (es)
CO (1) CO6321284A2 (es)
CR (1) CR11838A (es)
DO (1) DOP2010000342A (es)
EA (1) EA018817B1 (es)
ES (1) ES2455496T3 (es)
IL (1) IL209270A (es)
MA (1) MA32406B1 (es)
MX (1) MX2010012732A (es)
NZ (1) NZ589062A (es)
PE (1) PE20091927A1 (es)
TW (1) TW201008941A (es)
UY (1) UY31839A (es)
WO (1) WO2009141398A1 (es)
ZA (1) ZA201007945B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101257158B1 (ko) 2008-05-23 2013-04-23 노파르티스 아게 단백질 티로신 키나제 억제제로서의 퀴놀린 및 퀴녹살린의 유도체
WO2010043714A1 (en) 2008-10-17 2010-04-22 Glaxo Group Limited Tricyclic nitrogen compounds used as antibacterials
NZ603268A (en) * 2010-05-04 2015-02-27 Alkermes Pharma Ireland Ltd Process for synthesizing oxidized lactam compounds
CA2871270A1 (en) 2012-05-02 2013-11-07 Lupin Limited Substituted pyridine compounds as crac modulators
CN103113291B (zh) * 2013-02-04 2015-03-04 浙江大学 一种3位烯基吡啶衍生物的合成方法
SG11201700566SA (en) 2014-08-22 2017-03-30 Glaxosmithkline Ip Dev Ltd Tricyclic nitrogen containing compounds for treating neisseria gonorrhoea infection
KR20190019084A (ko) 2016-06-08 2019-02-26 아지엔드 키미쉐 리유나이트 안젤리니 프란체스코 에이.씨.알.에이.에프. 에스.피.에이 새로운 항박테리아 화합물
WO2021198981A1 (en) 2020-04-01 2021-10-07 Janssen Biopharma, Inc. Antiviral compounds and uses thereof
WO2023210599A1 (ja) 2022-04-25 2023-11-02 日本新薬株式会社 Ｄｄｒ１キナーゼ阻害剤としての化合物および医薬

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2344523T3 (es) * 2005-12-22 2010-08-30 Glaxo Group Limited Compuestos heterociclicos, su preparacion y su uso como agentes antibacterianos.
WO2007115947A1 (en) * 2006-04-06 2007-10-18 Glaxo Group Limited Pyrrolo-quinoxalinone derivatives as antibacterials
MY149347A (en) * 2007-04-20 2013-08-30 Glaxo Group Ltd Tricyclic nitrogen containing compounds as antibacterial agents
GB0707706D0 (en) * 2007-04-20 2007-05-30 Glaxo Group Ltd Compounds

Also Published As

Publication number Publication date
CA2725726A1 (en) 2009-11-26
MX2010012732A (es) 2010-12-07
DOP2010000342A (es) 2010-11-30
IL209270A (en) 2013-09-30
UY31839A (es) 2009-12-14
EP2300476B1 (en) 2014-01-08
AR071869A1 (es) 2010-07-21
BRPI0912995A2 (pt) 2015-10-13
CN102105473B (zh) 2013-05-08
US8097628B2 (en) 2012-01-17
EP2300476A1 (en) 2011-03-30
ES2455496T3 (es) 2014-04-15
KR20110016947A (ko) 2011-02-18
MA32406B1 (fr) 2011-06-01
AU2009248786A1 (en) 2009-11-26
US20090306089A1 (en) 2009-12-10
EA018817B1 (ru) 2013-10-30
WO2009141398A1 (en) 2009-11-26
ZA201007945B (en) 2011-08-31
IL209270A0 (en) 2011-01-31
JP5474941B2 (ja) 2014-04-16
AU2009248786B2 (en) 2013-04-04
TW201008941A (en) 2010-03-01
CR11838A (es) 2011-03-25
CN102105473A (zh) 2011-06-22
NZ589062A (en) 2012-06-29
PE20091927A1 (es) 2010-01-21
CO6321284A2 (es) 2011-09-20
EA201071352A1 (ru) 2011-06-30
JP2011520943A (ja) 2011-07-21

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