CL2007003191A1 - Compuestos derivados de pirimido-piridona, inhibidores de las proteina quinasas; composicion farmaceutica; y uso para el tratamiento de enfermedades tales como artritis, sindrome de colon irritable, sindrome disneico agudo del adulto, epoc y para el - Google Patents
Compuestos derivados de pirimido-piridona, inhibidores de las proteina quinasas; composicion farmaceutica; y uso para el tratamiento de enfermedades tales como artritis, sindrome de colon irritable, sindrome disneico agudo del adulto, epoc y para elInfo
- Publication number
- CL2007003191A1 CL2007003191A1 CL200703191A CL2007003191A CL2007003191A1 CL 2007003191 A1 CL2007003191 A1 CL 2007003191A1 CL 200703191 A CL200703191 A CL 200703191A CL 2007003191 A CL2007003191 A CL 2007003191A CL 2007003191 A1 CL2007003191 A1 CL 2007003191A1
- Authority
- CL
- Chile
- Prior art keywords
- syndrome
- piridona
- pirimido
- copd
- arthritis
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 2
- 102000001253 Protein Kinase Human genes 0.000 title 1
- 230000001154 acute effect Effects 0.000 title 1
- 206010003246 arthritis Diseases 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 208000002551 irritable bowel syndrome Diseases 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 108060006633 protein kinase Proteins 0.000 title 1
- 208000011580 syndromic disease Diseases 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
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- Virology (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurosurgery (AREA)
- Ophthalmology & Optometry (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pain & Pain Management (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Transplantation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85820306P | 2006-11-09 | 2006-11-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2007003191A1 true CL2007003191A1 (es) | 2008-06-20 |
Family
ID=38961448
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL200703191A CL2007003191A1 (es) | 2006-11-09 | 2007-11-06 | Compuestos derivados de pirimido-piridona, inhibidores de las proteina quinasas; composicion farmaceutica; y uso para el tratamiento de enfermedades tales como artritis, sindrome de colon irritable, sindrome disneico agudo del adulto, epoc y para el |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7645764B2 (es) |
| EP (1) | EP2094698A1 (es) |
| JP (1) | JP2010509265A (es) |
| CN (1) | CN101535308A (es) |
| AR (1) | AR063637A1 (es) |
| CA (1) | CA2668731A1 (es) |
| CL (1) | CL2007003191A1 (es) |
| PE (1) | PE20081159A1 (es) |
| TW (1) | TW200829251A (es) |
| WO (1) | WO2008055842A1 (es) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JO2985B1 (ar) | 2006-12-20 | 2016-09-05 | Takeda Pharmaceuticals Co | مثبطات كينازmapk/erk |
| WO2010071846A2 (en) | 2008-12-19 | 2010-06-24 | Afraxis, Inc. | Compounds for treating neuropsychiatric conditions |
| WO2011044535A2 (en) | 2009-10-09 | 2011-04-14 | Afraxis, Inc. | 8-ethyl-6-(aryl)pyrido[2,3-d]pyrimidin-7(8h)-ones for the treatment of cns disorders |
| MX2013011518A (es) * | 2011-04-08 | 2014-06-04 | Afraxis Holdings Inc | 8-etil-6-(aril)pirido[2,3-d]pirimidin-7(8h)-onas para el tratamiento de desordenes del sistema nervioso y cancer. |
| AU2012257347A1 (en) * | 2011-05-17 | 2014-01-09 | Joint Stock Company "Pharmasyntez" | Compounds, pharmaceutical compositions and a method for the prophylaxis and treatment of the adhesion process |
| EA201490925A1 (ru) * | 2011-11-04 | 2014-09-30 | Афраксис Холдингз, Инк. | Ингибиторы pak для лечения синдрома умственной отсталости, сцепленного с ломкой х хромосомой |
| US9408885B2 (en) | 2011-12-01 | 2016-08-09 | Vib Vzw | Combinations of therapeutic agents for treating melanoma |
| NZ711376A (en) | 2013-03-15 | 2020-01-31 | Sanofi Sa | Heteroaryl compounds and uses thereof |
| PE20151776A1 (es) | 2013-03-15 | 2015-12-11 | Celgene Avilomics Res Inc | Compuestos de heteroarilo y sus usos |
| AR095464A1 (es) | 2013-03-15 | 2015-10-21 | Celgene Avilomics Res Inc | Compuestos de heteroarilo y usos de los mismos |
| JP6631616B2 (ja) | 2014-07-26 | 2020-01-15 | ノース・アンド・サウス・ブラザー・ファーマシー・インベストメント・カンパニー・リミテッド | ＣＤＫ阻害剤としての２−アミノ−ピリド［２，３−ｄ］ピリミジン−７（８Ｈ）−オン誘導体及びその使用 |
| EP3579872A1 (en) | 2017-02-10 | 2019-12-18 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for the treatment of cancers associated with activation of the mapk pathway |
| EP3732285A1 (en) | 2017-12-28 | 2020-11-04 | Tract Pharmaceuticals, Inc. | Stem cell culture systems for columnar epithelial stem cells, and uses related thereto |
| CN108440278B (zh) * | 2018-03-07 | 2021-01-12 | 中国计量大学 | 一种二羧基查尔酮类化合物及其在制备抗炎药物中的应用 |
| TWI831829B (zh) | 2018-09-12 | 2024-02-11 | 美商建南德克公司 | 苯氧基-吡啶基-嘧啶化合物及使用方法 |
| TWI748317B (zh) | 2019-01-03 | 2021-12-01 | 美商建南德克公司 | 吡啶并－嘧啶酮與喋啶酮化合物及使用方法 |
| WO2021122645A1 (en) | 2019-12-20 | 2021-06-24 | Syngenta Crop Protection Ag | Pesticidally active azole-amide compounds |
| CN113416197B (zh) * | 2021-08-25 | 2021-12-28 | 北京鑫开元医药科技有限公司 | 甲酰胺类衍生物、制备方法、药物组合物及应用 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4271164A (en) * | 1979-04-16 | 1981-06-02 | Warner-Lambert Company | 6-Substituted-arylpyrido[2,3-d]pyrimidin-7-amines and derivatives |
| US5338740A (en) * | 1993-07-13 | 1994-08-16 | Pfizer Inc. | Angiotensin II receptor antagonists |
| US5620961A (en) * | 1994-04-25 | 1997-04-15 | Markovic; Nenad S. | Fructose ester-β-cyclodextrin complexes and processes for making and using same |
| MX9702245A (es) * | 1994-11-14 | 1997-06-28 | Warner Lambert Co | Seis-aril-pirido(2,3-d)pirimidinas y naftiridinas para inhibir la proliferacion celular mediada por la proteina cinasa tirosina. |
| IL115256A0 (en) * | 1994-11-14 | 1995-12-31 | Warner Lambert Co | 6-Aryl pyrido (2,3-d) pyrimidines and naphthyridines and their use |
| US5620981A (en) * | 1995-05-03 | 1997-04-15 | Warner-Lambert Company | Pyrido [2,3-D]pyrimidines for inhibiting protein tyrosine kinase mediated cellular proliferation |
| US6498163B1 (en) * | 1997-02-05 | 2002-12-24 | Warner-Lambert Company | Pyrido[2,3-D]pyrimidines and 4-aminopyrimidines as inhibitors of cellular proliferation |
| ES2235353T3 (es) * | 1997-08-20 | 2005-07-01 | Warner-Lambert Company Llc | Naftridonas para inhibir la proteina tirasina quinasa y proliferacion celular mediada por la quinasa del ciclo celular. |
| WO1999037643A1 (en) | 1998-01-26 | 1999-07-29 | Yamanouchi Pharmaceutical Co., Ltd. | Novel benzene-fused heterocyclic derivatives or salts thereof |
| US7053070B2 (en) * | 2000-01-25 | 2006-05-30 | Warner-Lambert Company | Pyrido[2,3-d]pyrimidine-2,7-diamine kinase inhibitors |
| MXPA02011263A (es) * | 2000-08-04 | 2003-03-10 | Warner Lambert Co | 2-(4-piridil)amino-6-dialcoxifenil- pirido(2,3-d) pirimidin-7-onas. |
| CA2420286A1 (en) | 2000-08-31 | 2002-03-07 | F. Hoffmann-La Roche Ag | 7-oxo pyridopyrimidines as inhibitors of a cellular proliferation |
| US6506749B2 (en) * | 2000-08-31 | 2003-01-14 | Syntex (U.S.A.) Llc | 7-oxo-pyridopyrimidines (I) |
| BR0113590A (pt) * | 2000-08-31 | 2003-07-22 | Hoffmann La Roche | 7-oxo-piridopirimidinas |
| AU2001292320A1 (en) | 2000-10-02 | 2002-04-15 | Tanabe Seiyaku Co., Ltd. | Benzylamine compound, process for producing the same, and intermediate therefor |
| OA12755A (en) * | 2002-01-22 | 2006-07-03 | Warner Lambert Co | 2-(pyridin-2-ylamino)-pyridoÄ2,3dÜpyrimidin-7-ones. |
| US7196090B2 (en) * | 2002-07-25 | 2007-03-27 | Warner-Lambert Company | Kinase inhibitors |
| BRPI0415210A (pt) * | 2003-10-08 | 2006-12-05 | Irm Llc | compostos e composições como inibidores de proteìna cinase |
| GB0402140D0 (en) | 2004-01-30 | 2004-03-03 | Smithkline Beecham Corp | Novel compounds |
| GB0402138D0 (en) | 2004-01-30 | 2004-03-03 | Smithkline Beecham Corp | Novel compounds |
| GB0402143D0 (en) | 2004-01-30 | 2004-03-03 | Smithkline Beecham Corp | Novel compounds |
| GB0402137D0 (en) | 2004-01-30 | 2004-03-03 | Smithkline Beecham Corp | Novel compounds |
| BRPI0507852A (pt) * | 2004-02-18 | 2007-07-10 | Warner Lambert Co | 2-(piridin-3-ilamino)-pirido[2,3-d]pirimidin-7-onas |
| US20090036472A1 (en) * | 2005-02-02 | 2009-02-05 | Palle Venkata P | Azabicyclo derivatives as anti-inflammatory agents |
| MX2008014618A (es) * | 2006-05-15 | 2008-11-28 | Irm Llc | Composiciones y metodos para inhibidores de cinasas del receptor fgf. |
-
2007
- 2007-10-31 CA CA002668731A patent/CA2668731A1/en not_active Abandoned
- 2007-10-31 CN CNA200780041507XA patent/CN101535308A/zh active Pending
- 2007-10-31 WO PCT/EP2007/061782 patent/WO2008055842A1/en not_active Ceased
- 2007-10-31 EP EP07857196A patent/EP2094698A1/en not_active Withdrawn
- 2007-10-31 JP JP2009535682A patent/JP2010509265A/ja active Pending
- 2007-11-06 CL CL200703191A patent/CL2007003191A1/es unknown
- 2007-11-06 TW TW096141896A patent/TW200829251A/zh unknown
- 2007-11-07 PE PE2007001532A patent/PE20081159A1/es not_active Application Discontinuation
- 2007-11-08 US US11/983,313 patent/US7645764B2/en not_active Expired - Fee Related
- 2007-11-09 AR ARP070105000A patent/AR063637A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2010509265A (ja) | 2010-03-25 |
| EP2094698A1 (en) | 2009-09-02 |
| PE20081159A1 (es) | 2008-08-15 |
| US20080132528A1 (en) | 2008-06-05 |
| AR063637A1 (es) | 2009-02-04 |
| US7645764B2 (en) | 2010-01-12 |
| TW200829251A (en) | 2008-07-16 |
| CA2668731A1 (en) | 2008-05-15 |
| WO2008055842A1 (en) | 2008-05-15 |
| CN101535308A (zh) | 2009-09-16 |
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