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BR9507811B1 - polipeptìdeos e composição farmacêutica. - Google Patents

polipeptìdeos e composição farmacêutica.

Info

Publication number
BR9507811B1
BR9507811B1 BRPI9507811-8A BR9507811A BR9507811B1 BR 9507811 B1 BR9507811 B1 BR 9507811B1 BR 9507811 A BR9507811 A BR 9507811A BR 9507811 B1 BR9507811 B1 BR 9507811B1
Authority
BR
Brazil
Prior art keywords
pct
image
polypeptides
phe
sec
Prior art date
Application number
BRPI9507811-8A
Other languages
English (en)
Other versions
BR9507811A (pt
Inventor
Klaus P Schaefer
Klaus Melchers
Ruediger Nave
Wolf-Ruediger Ulrich
Ernst Sturm
Uwe Krueger
Dietrich Haefner
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6519392&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9507811(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of BR9507811A publication Critical patent/BR9507811A/pt
Publication of BR9507811B1 publication Critical patent/BR9507811B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
BRPI9507811-8A 1994-05-31 1995-05-27 polipeptìdeos e composição farmacêutica. BR9507811B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4418936A DE4418936A1 (de) 1994-05-31 1994-05-31 Polypeptid
PCT/EP1995/002028 WO1995032992A1 (de) 1994-05-31 1995-05-27 Synthetische peptidanaloge des lungenoberflächenproteins sp-c

Publications (2)

Publication Number Publication Date
BR9507811A BR9507811A (pt) 1997-09-16
BR9507811B1 true BR9507811B1 (pt) 2009-05-05

Family

ID=6519392

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9507811-8A BR9507811B1 (pt) 1994-05-31 1995-05-27 polipeptìdeos e composição farmacêutica.

Country Status (28)

Country Link
US (1) US5874406A (pt)
EP (1) EP0764172B1 (pt)
JP (1) JP3359638B2 (pt)
KR (1) KR100355626B1 (pt)
CN (1) CN1130374C (pt)
AT (1) ATE275154T1 (pt)
AU (1) AU690280B2 (pt)
BG (1) BG63210B1 (pt)
BR (1) BR9507811B1 (pt)
CA (1) CA2191344C (pt)
CY (1) CY2552B1 (pt)
CZ (1) CZ286976B6 (pt)
DE (2) DE4418936A1 (pt)
DK (1) DK0764172T3 (pt)
EE (1) EE03775B1 (pt)
ES (1) ES2227548T3 (pt)
FI (1) FI118126B (pt)
HU (1) HU220191B (pt)
NO (1) NO317149B1 (pt)
NZ (1) NZ287447A (pt)
PL (1) PL181234B1 (pt)
PT (1) PT764172E (pt)
RO (1) RO118752B1 (pt)
RU (1) RU2145611C1 (pt)
SI (1) SI0764172T1 (pt)
SK (1) SK282441B6 (pt)
UA (1) UA35636C2 (pt)
WO (1) WO1995032992A1 (pt)

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WO1997035882A1 (en) * 1996-03-27 1997-10-02 Ortho Pharmaceutical Corporation Lyophilized pulmonary surfactant peptide compositions
DE19851119C2 (de) 1998-11-06 2001-05-31 Byk Gulden Lomberg Chem Fab Behälter und Vorrichtung zur Blindung der Verabreichung von nicht festen pharmazeutischen Darreichungsformen bei der klinischen Prüfung
IT1308180B1 (it) * 1999-02-12 2001-12-07 Chiesi Farma Spa Peptidi sintetici aventi la capacita' di diminuire la tensionesuperficiale e loro impiego nella preparazione di un surfattante
WO2000076535A1 (en) * 1999-06-11 2000-12-21 Byk Gulden Lomberg Chemische Fabrik Gmbh Pharmaceutical preparation containing modifications of surfactant protein b (sp-b) and surfactant protein c (sp-c)
WO2000078810A1 (en) * 1999-06-17 2000-12-28 Byk Gulden Lomberg Chemische Fabrik Gmbh Surfactant protein c esters
AU6083899A (en) 1999-09-16 2001-04-17 Aventis Behring Gmbh Combination of c1-inh and lung surfactant for the treatment of respiratory disorders
AU2003201A (en) * 1999-12-01 2001-06-12 Byk Gulden Lomberg Chemische Fabrik Gmbh Novel use of lung surfactant
US20030091509A1 (en) * 2000-02-11 2003-05-15 Haefner Dietrich Novel use of pulmonary surfactant for the prophylaxis and treatment of chronic pulmonary diseases
US6660833B1 (en) 2000-02-29 2003-12-09 Harbor-Ucla Research And Education Institute Respiratory distress syndrome therapy with peptide analogs of human SP-B
DK1276495T3 (da) * 2000-04-12 2006-08-14 Altana Pharma Ag Anvendelse af rekombinante lungesurfactant-præparater til tidlig behandling af akutte lungesygdomme
US20040254112A1 (en) * 2000-04-12 2004-12-16 Dietrich Hafner Use of pulmonary surfactant for the early treatment of acute pulmonary diseases
DE10018022A1 (de) * 2000-04-12 2001-10-31 Byk Gulden Lomberg Chem Fab Neue Verwendung von Lungensurfactant zur Prophylaxe oder Frühbehandlung von akuten Lungenerkrankungen
RU2161501C1 (ru) * 2000-06-29 2001-01-10 Санкт-Петербургская Общественная Организация "Санкт-Петербургский Институт Биорегуляции И Геронтологии Сзо Рамн" Способ получения пептидов, обладающих тканеспецифической активностью, и фармацевтические композиции на их основе
ATE468131T1 (de) 2001-10-11 2010-06-15 Nycomed Gmbh Neue verwendung von lungensurfactant
US6998384B2 (en) 2001-12-12 2006-02-14 The Penn State Research Foundation Surfactant prevention of lung complications from cancer chemotherapy
US8236750B2 (en) * 2004-08-06 2012-08-07 Nycomed Gmbh Composition comprising a pulmonary surfactant and a TNF-derived peptide
US7464012B2 (en) * 2004-12-10 2008-12-09 L'air Liquide, Societe Anonyme A Directoire Et Conseil De Surveillance Pour L'etude Et L'exploitation Des Procedes Georges Claude Simplified process simulator
US7582312B2 (en) 2004-11-15 2009-09-01 Discovery Laboratories, Inc. Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof
US8337815B2 (en) 2004-12-23 2012-12-25 Discovery Laboratories, Inc. Pulmonary surfactant formulations
PL1841458T3 (pl) 2005-01-06 2012-05-31 Discovery Lab Inc Schemat stosowania środka powierzchniowo czynnego do leczenia lub zapobiegania dysplazji oskrzelowo-płucnej
DE102005014650B3 (de) * 2005-03-31 2006-08-17 Altana Pharma Ag Anordnung aus Katheter und Anschlussstück sowie Ventil zum Durchführen eines Katheters
DE102005016229B3 (de) 2005-04-08 2006-06-14 Altana Pharma Ag Trockenvernebler
WO2008036293A1 (en) * 2006-09-19 2008-03-27 Discovery Laboratories, Inc. Pulmonary surfactant formulations and methods for promoting mucus clearance
US7951781B2 (en) 2006-11-02 2011-05-31 University Of Iowa Research Foundation Methods and compositions related to PLUNC surfactant polypeptides
EP2009023A1 (en) * 2007-06-04 2008-12-31 Rentschler Beteiligungs GmbH Novel peptides and their use for the treatment of edema
US8048043B2 (en) 2007-06-08 2011-11-01 Chiesi Farmaceutici S. P. A. Method of administration of a pulmonary surfactant
CA2744940A1 (en) 2008-12-10 2010-06-17 Paka Pulmonary Pharmaceuticals, Inc. Methods and compositions for delivery of medicaments to the lungs
CA2773490A1 (en) 2009-09-08 2011-03-17 Chiesi Farmaceutici S.P.A. A therapeutic combination comprising a pulmonary surfactant and antioxidant enzymes
RU2415676C1 (ru) * 2009-12-09 2011-04-10 Общество С Ограниченной Ответственностью "Гармония" Способ получения средства, обладающего тканеспецифической активностью, и средство, полученное данным способом (варианты)
EA201300255A1 (ru) * 2010-08-23 2013-06-28 Такеда Гмбх Увлажненные частицы, содержащие терапевтически активное вещество
US9815869B2 (en) 2012-02-09 2017-11-14 University Of Rochester SP-B and SP-C peptides, synthetic lung surfactants, and use thereof
US20130303726A1 (en) * 2012-04-17 2013-11-14 Chiesi Farmaceutici S.P.A. Method for the preparation of surfactant peptides
WO2013188016A2 (en) 2012-05-04 2013-12-19 Discovery Laboratories, Inc. Surfactant therapy for exposure to ionizing radiation
CN106163600B (zh) 2014-03-05 2019-03-22 弗劳恩霍夫应用研究促进协会 用于对气溶胶进行加湿的加湿器
EP3106090A1 (en) 2015-06-15 2016-12-21 CHIESI FARMACEUTICI S.p.A. System for effective breath-synchronized delivery of medicament to the lungs
EP3285645B1 (en) 2015-04-22 2020-08-12 Chiesi Farmaceutici S.p.A. System for effective breath-synchronized delivery of medicament to the lungs
US11311691B2 (en) 2015-04-28 2022-04-26 Chiesi Farmaceutici S.P.A Device for facilitating the administration of a medicament to the lung by a catheter
JP2018514545A (ja) * 2015-04-30 2018-06-07 ユニバーシティ オブ ブレーメン 医療用および美容用の新規な皮膚ケア製造物
EP3490649A1 (en) 2016-07-28 2019-06-05 Chiesi Farmaceutici S.p.A. Method and system for delivery of an aerosolized medicament
MA46605A (fr) 2016-10-26 2021-06-02 Chiesi Farm Spa Dispositif permettant de faciliter l'administration d'un médicament aux poumons par l'intermédiaire d'un cathéter
BR112019012922A2 (pt) 2016-12-22 2019-12-10 Chiesi Farm Spa combinação de um surfactante pulmonar, uso de uma combinação de um surfactante pulmonar e kit
CN107163148A (zh) * 2017-05-15 2017-09-15 重庆理工大学 肺表面活性蛋白b前肽的重组蛋白及其制备方法和应用
WO2019115771A1 (en) 2017-12-15 2019-06-20 Pari Pharma Gmbh Nebuliser system, holding system, combination comprising nebuliser system and holding system, and aerosol administration method
TW201927286A (zh) 2017-12-15 2019-07-16 義大利商凱西製藥公司 用於噴霧投藥之包含肺表面張力素的藥學調配物
JP7378425B2 (ja) 2018-04-23 2023-11-13 シエシー ファルマセウティチィ ソシエタ ペル アチオニ 肺サーファクタントおよびｂｐｄの予防のためのステロイドを含む治療的組合せ
CN109001466A (zh) * 2018-07-19 2018-12-14 新疆维吾尔自治区人民医院 一种用于osa的肺表面活性蛋白试剂盒及其应用
EP3666315A1 (en) 2018-12-14 2020-06-17 PARI Pharma GmbH Aerosol delivery device and method of operating the aerosol delivery device
EP3666316A1 (en) 2018-12-14 2020-06-17 PARI Pharma GmbH Aerosol delivery device and method of operating the aerosol delivery device
EP3843105A1 (en) 2019-12-23 2021-06-30 PARI Pharma GmbH Control device for aerosol nebulizer system
WO2021151853A1 (en) 2020-01-28 2021-08-05 Chiesi Farmaceutici S.P.A. Polypeptides having improved properties
EP4411745A1 (en) 2023-02-01 2024-08-07 Pari Medical Holding GmbH Medical evaluation method, aerosol nebulizer and medical evaluation system
EP4464354A1 (en) 2023-05-15 2024-11-20 Pari Medical Holding GmbH Method of operating an inhalation device, inhalation device and inhalation device system for providing inhalation process/breath guiding
EP4464236A1 (en) 2023-05-15 2024-11-20 Pari Medical Holding GmbH Method of operating an inhalation device, inhalation device and inhalation device system for providing inhalation process feedback

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JPS59164724A (ja) * 1983-03-10 1984-09-17 Tokyo Tanabe Co Ltd サ−フアクタント及びそれを含有する呼吸窮迫症候群治療剤
US4933280A (en) * 1984-12-11 1990-06-12 California Biotechnology Inc. Recombinant DNA sequence encoding Alveolar Surfactant Protein
US5169761A (en) * 1984-12-11 1992-12-08 California Biotechnology Inc. Dna encoding and expression systems for alveolar surfactant proteins
US4659805A (en) * 1984-12-11 1987-04-21 California Biotechnology, Inc. Recombinant alveolar surfactant protein
US5104853A (en) * 1984-12-11 1992-04-14 California Biotechnology Inc. Alveolar surfactant proteins having cys to ser mutations
US5013720A (en) * 1986-05-06 1991-05-07 Abbott Laboratories SAP-6-Val proteins and methods
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JPH05294996A (ja) * 1992-04-17 1993-11-09 Tokyo Tanabe Co Ltd 合成ペプチド、それを含有する肺サーファクタント及び呼吸窮迫症候群治療剤

Also Published As

Publication number Publication date
ES2227548T3 (es) 2005-04-01
PL317420A1 (en) 1997-04-14
UA35636C2 (uk) 2001-04-16
KR100355626B1 (ko) 2002-12-26
CN1130374C (zh) 2003-12-10
HUT76952A (hu) 1998-01-28
DE59510941D1 (de) 2004-10-07
NO965052D0 (no) 1996-11-27
KR970703367A (ko) 1997-07-03
EE03775B1 (et) 2002-06-17
DK0764172T3 (da) 2005-01-10
BR9507811A (pt) 1997-09-16
NO317149B1 (no) 2004-08-30
HU9603249D0 (en) 1997-01-28
PT764172E (pt) 2005-01-31
CA2191344C (en) 2003-04-08
CZ350296A3 (en) 1997-05-14
FI964766A0 (fi) 1996-11-29
PL181234B1 (pl) 2001-06-29
JPH10504025A (ja) 1998-04-14
SI0764172T1 (en) 2005-02-28
FI118126B (fi) 2007-07-13
EP0764172B1 (de) 2004-09-01
CA2191344A1 (en) 1995-12-07
CZ286976B6 (en) 2000-08-16
SK282441B6 (sk) 2002-02-05
MX9605986A (es) 1998-06-30
BG101028A (en) 1998-01-30
JP3359638B2 (ja) 2002-12-24
SK152496A3 (en) 1997-06-04
ATE275154T1 (de) 2004-09-15
HK1000891A1 (en) 2004-09-17
DE4418936A1 (de) 1996-02-08
CY2552B1 (en) 2008-07-02
BG63210B1 (bg) 2001-06-29
WO1995032992A1 (de) 1995-12-07
EP0764172A1 (de) 1997-03-26
FI964766A7 (fi) 1996-11-29
AU690280B2 (en) 1998-04-23
HU220191B (hu) 2001-11-28
RO118752B1 (ro) 2003-10-30
CN1154117A (zh) 1997-07-09
US5874406A (en) 1999-02-23
EE9600175A (et) 1997-06-16
RU2145611C1 (ru) 2000-02-20
AU2616995A (en) 1995-12-21
NZ287447A (en) 1998-01-26
NO965052L (no) 1997-01-28

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Legal Events

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B25D Requested change of name of applicant approved
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06G Technical and formal requirements: other requirements [chapter 6.7 patent gazette]

Free format text: O REQUERENTE DEVERA COMPLEMENTAR A TAXA RELATIVA A 1 REVINDICACAO EXEDENTE. O PEDIDO DE EXAME ( FOLHA 52 ) REFERE-SE A 11 REVINDICACOES, POREM O REQUERENTE DEPOSITOU 12 REVINDICACOES ( FOLHAS 136 E138 ).

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B25D Requested change of name of applicant approved

Owner name: NYCOMED GMBH (DE)

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B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

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Free format text: INPI-52400.061558/2013 ORIGEM: JUIZO DA 013A VARA FEDERAL DO RIO DE JANEIRO PROCESSO NO0132272-32.2013.4.02.5101 ACAO DE NULIDADE DAS PATENTES SUBMETIDAS AO MAILBOX (ART. 229, PARAGRAFO UNICO DA LPI); ALTERNATIVAMENTE, A DECRETACAO DA NULIDADE PARCIAL PARA CORRECAO DO PRAZO DE VIGENCIA; SUBSIDIARIAMENTE, CASO SE ENTENDA NAO SER O CASO DE NULIDADE, A CORRECAO DO ATO ADMINISTRATIVO PARA ADEQUACAO DA VIGENCIA DAS PATENTES. AUTOR: INSTITUTO NACIONAL DA PROPRIEDADE INDUSTRIAL - INPI REU: NYCOMED GMBH, OKLAHOMA STATE UNIVERSITY, REGESTS OF THE UNIVERSITY OF MINNESOTA, OTSUKA PHARMACEUTICAL CO LTD, PLASMASEAL CORPORATION

B21B Extinction acc. art. 78, item ii - on waiver by the patentee, without prejudice to the rights of third parties

Free format text: SOLICITADA ATRAVES DA PETICAO 860130004420, DE 14/10/2013

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Free format text: A PETICAO DE NO 20130064421, APRESENTADA EM 23/07/2013, EM VIRTUDE DO DISPOSTO NOS ARTS. 218 OU 219 DA LPI (LEI 9279 / 96) DE 14/05/1996, E CONSIDERADA COMO PETICAO NAO CONHECIDA EM VIRTUDE DA EXTINCAO DA PATENTE PUBLICADA NA RPI NO 2241, DE 17/12/2013.

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Free format text: INPI-52400.061558/2013-85 13A VARA FEDERAL DO RIO DE JANEIRO ORDINARIA / PROPRIEDADE INDUSTRIAL PROCESSO : 0132272-32.2013.4.02.5101 (2013.51.01.132272-3) AUTOR: INSTITUTO NACIONAL DA PROPRIEDADE INDUSTRIAL INPI REU: REGENTS OF THE UNIVERSITY OF MINNESOTA, OKLAHOMA STATE UNIVERSITY, OTSUKA PHARMACEUTICAL CO. LTD., PLASMASEAL CORPORATION E NYCOMED GMBH. DECISAO: HOMOLOGO, POR SENTENCA, PARA QUE SE PRODUZA OS SEUS JURIDICOS E LEGAIS EFEITOS, OS ACORDOS FIRMADOS ENTRE O INPI E AS RES, CONFORME FLS. 87/89, 93/96, 138/139, 192/193 E 245, JULGANDO EXTINTO O PROCESSO, COM RESOLUCAO DO MERITO, NOS MOLDES DO ARTIGO 269, III DO CODIGO DO PROCESSO CIVIL, EM RELACAO AS ALUDIDAS EMPRESAS RES E AO

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