AR053948A1 - Deteccion de un antigeno diana independientemente de la presencia o ausencia de un anticuerpo terapeutico correspondiente - Google Patents
Deteccion de un antigeno diana independientemente de la presencia o ausencia de un anticuerpo terapeutico correspondienteInfo
- Publication number
- AR053948A1 AR053948A1 ARP060102872A ARP060102872A AR053948A1 AR 053948 A1 AR053948 A1 AR 053948A1 AR P060102872 A ARP060102872 A AR P060102872A AR P060102872 A ARP060102872 A AR P060102872A AR 053948 A1 AR053948 A1 AR 053948A1
- Authority
- AR
- Argentina
- Prior art keywords
- therapeutic antibody
- diana
- ancient
- absence
- independently
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title abstract 5
- 238000001514 detection method Methods 0.000 title 1
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
La presente está relacionada con el campo de los anticuerpos terapéuticos. La presente especialmente está relacionada con un método para la deteccion del antígeno diana de un anticuerpo terapéutico en una muestra que consiste en los siguientes pasos: a) proporcionar la muestra a analizar; b) incubar dicha muestra con dicho anticuerpo terapéutico bajo las condiciones apropiadas para unir dicho anticuerpo terapéutico a dicho antígeno diana, de manera que se forme un complejo de antígeno diana-anticuerpo terapéutico y c) detectar el complejo formado en b).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05014618 | 2005-07-06 | ||
| EP06004447 | 2006-03-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR053948A1 true AR053948A1 (es) | 2007-05-23 |
Family
ID=36922121
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP060102872A AR053948A1 (es) | 2005-07-06 | 2006-07-04 | Deteccion de un antigeno diana independientemente de la presencia o ausencia de un anticuerpo terapeutico correspondiente |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20070009976A1 (es) |
| EP (2) | EP2194380A3 (es) |
| JP (1) | JP2008545145A (es) |
| KR (1) | KR20080016939A (es) |
| AR (1) | AR053948A1 (es) |
| AU (1) | AU2006265275A1 (es) |
| BR (1) | BRPI0612591A2 (es) |
| CA (1) | CA2613187A1 (es) |
| CR (1) | CR9635A (es) |
| EC (1) | ECSP088081A (es) |
| IL (1) | IL188317A0 (es) |
| MA (1) | MA29730B1 (es) |
| MX (1) | MX2008000277A (es) |
| MY (1) | MY157955A (es) |
| NO (1) | NO20076662L (es) |
| NZ (1) | NZ564471A (es) |
| RU (1) | RU2008103608A (es) |
| TW (1) | TWI312864B (es) |
| WO (1) | WO2007003420A1 (es) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL152656A0 (en) | 2000-05-19 | 2003-06-24 | Genentech Inc | Gene detection assay for improving the likelihood of an effective response to an erbb antagonist cancer therapy |
| AU2005287404B2 (en) * | 2004-07-22 | 2009-05-07 | Genentech, Inc. | HER2 antibody composition |
| EP1795004B1 (en) | 2004-10-01 | 2015-02-25 | The Board Of Trustees Of The Leland Stanford Junior University | Imaging arrangement and method therefor |
| JO3000B1 (ar) * | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
| CN103251946A (zh) | 2005-02-23 | 2013-08-21 | 健泰科生物技术公司 | 使用her二聚化抑制剂在癌症患者中延长病情进展前时间或存活 |
| PE20070207A1 (es) * | 2005-07-22 | 2007-03-09 | Genentech Inc | Tratamiento combinado de los tumores que expresan el her |
| WO2007092581A2 (en) | 2006-02-07 | 2007-08-16 | The Board Of Trustees Of The Leland Stanford Junior University | Correction of optical aberrations |
| US8358354B2 (en) | 2009-01-26 | 2013-01-22 | The Board Of Trustees Of The Leland Stanford Junior University | Correction of optical abberations |
| PE20090681A1 (es) | 2007-03-02 | 2009-06-10 | Genentech Inc | Prediccion de respuesta a un inhibidor her |
| TWI472339B (zh) | 2008-01-30 | 2015-02-11 | Genentech Inc | 包含結合至ｈｅｒ２結構域ii之抗體及其酸性變異體的組合物 |
| BRPI0812682A2 (pt) | 2008-06-16 | 2010-06-22 | Genentech Inc | tratamento de cáncer de mama metastático |
| DK4403228T3 (da) | 2011-10-14 | 2025-10-13 | Hoffmann La Roche | Anvendelser for og fremstillet artikel indbefattende HER2-dimeriseringshæmmeren pertuzumab |
| KR101327542B1 (ko) * | 2012-03-15 | 2013-11-08 | 광주과학기술원 | 양자점 기반의 경쟁 면역분석법 및 다중 유세포 분석법을 이용한 시료 중 오염물질의 검출 방법 |
| AU2012232949B2 (en) * | 2012-09-28 | 2014-07-03 | Willowtree Holdings Pty Ltd | Temporary bulkhead |
| RU2737727C2 (ru) | 2013-04-16 | 2020-12-02 | Дженентек, Инк. | Варианты пертузумаба и их аналитическая характеристика |
| RU2020120593A (ru) | 2014-04-25 | 2020-09-01 | Дженентек, Инк. | Способы лечения раннего рака молочной железы трастузумабом-mcc-dm1 и пертузумабом |
| ES2984592T3 (es) | 2015-05-30 | 2024-10-30 | Hoffmann La Roche | Procedimientos de tratamiento de cáncer de mama metastásico no tratado previamente positivo para HER2 |
| WO2017087280A1 (en) | 2015-11-16 | 2017-05-26 | Genentech, Inc. | Methods of treating her2-positive cancer |
| AU2017387909A1 (en) | 2016-12-28 | 2019-06-27 | Genentech, Inc. | Treatment of advanced HER2 expressing cancer |
| TW202508629A (zh) | 2017-01-17 | 2025-03-01 | 美商建南德克公司 | 皮下her2抗體調配物 |
| KR20230144110A (ko) | 2017-03-02 | 2023-10-13 | 제넨테크, 인크. | Her2-양성 유방암 어쥬번트 치료 |
| KR20190140952A (ko) | 2017-04-24 | 2019-12-20 | 제넨테크, 인크. | 막관통 및 인접막 도메인에서의 erbb2/her2 돌연변이 |
| JP2023532122A (ja) | 2020-06-29 | 2023-07-26 | ジェネンテック， インコーポレイテッド | ペルツズマブにトラスツズマブを加えた固定用量配合剤 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2095818B (en) | 1981-03-27 | 1985-10-02 | Exxon Research Engineering Co | Staged adsorption/resorption heat pump |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| EP0590058B1 (en) * | 1991-06-14 | 2003-11-26 | Genentech, Inc. | HUMANIZED Heregulin ANTIBODy |
| WO1993021319A1 (en) | 1992-04-08 | 1993-10-28 | Cetus Oncology Corporation | HUMANIZED C-erbB-2 SPECIFIC ANTIBODIES |
| JP2001504326A (ja) | 1996-10-18 | 2001-04-03 | ジェネンテック インコーポレーテッド | 抗ＥｒｂＢ２抗体 |
| JP4424987B2 (ja) * | 2001-09-20 | 2010-03-03 | ボード オブ リージェンツ， ザ ユニバーシティ オブ テキサス システム | Ｅｌｉｓａアッセイを用いた循環する治療抗体、抗原および抗原／抗体複合体の測定 |
| EP2263691B1 (en) * | 2002-07-15 | 2012-08-29 | F.Hoffmann-La Roche Ag | Treatment of cancer with the recombinant humanized monoclonal anti-erbb2 antibody 2C4 (rhuMAb 2C4) |
-
2006
- 2006-06-29 MY MYPI20063118A patent/MY157955A/en unknown
- 2006-06-29 US US11/477,772 patent/US20070009976A1/en not_active Abandoned
- 2006-07-04 AR ARP060102872A patent/AR053948A1/es not_active Application Discontinuation
- 2006-07-04 TW TW095124248A patent/TWI312864B/zh active
- 2006-07-05 BR BRPI0612591-3A patent/BRPI0612591A2/pt not_active IP Right Cessation
- 2006-07-05 AU AU2006265275A patent/AU2006265275A1/en not_active Abandoned
- 2006-07-05 RU RU2008103608/15A patent/RU2008103608A/ru unknown
- 2006-07-05 JP JP2008519853A patent/JP2008545145A/ja active Pending
- 2006-07-05 EP EP10157725A patent/EP2194380A3/en not_active Withdrawn
- 2006-07-05 NZ NZ564471A patent/NZ564471A/en unknown
- 2006-07-05 KR KR1020087000259A patent/KR20080016939A/ko not_active Ceased
- 2006-07-05 CA CA002613187A patent/CA2613187A1/en not_active Abandoned
- 2006-07-05 MX MX2008000277A patent/MX2008000277A/es not_active Application Discontinuation
- 2006-07-05 EP EP06754671A patent/EP1902315A1/en not_active Withdrawn
- 2006-07-05 WO PCT/EP2006/006524 patent/WO2007003420A1/en not_active Ceased
-
2007
- 2007-12-20 IL IL188317A patent/IL188317A0/en unknown
- 2007-12-21 CR CR9635A patent/CR9635A/es not_active Application Discontinuation
- 2007-12-28 NO NO20076662A patent/NO20076662L/no not_active Application Discontinuation
-
2008
- 2008-01-04 EC EC2008008081A patent/ECSP088081A/es unknown
- 2008-02-01 MA MA30617A patent/MA29730B1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ564471A (en) | 2010-04-30 |
| EP2194380A2 (en) | 2010-06-09 |
| EP2194380A3 (en) | 2010-07-14 |
| TW200741203A (en) | 2007-11-01 |
| NO20076662L (no) | 2008-04-03 |
| RU2008103608A (ru) | 2009-08-20 |
| WO2007003420A1 (en) | 2007-01-11 |
| EP1902315A1 (en) | 2008-03-26 |
| CR9635A (es) | 2008-02-20 |
| KR20080016939A (ko) | 2008-02-22 |
| ECSP088081A (es) | 2008-02-20 |
| JP2008545145A (ja) | 2008-12-11 |
| BRPI0612591A2 (pt) | 2010-11-23 |
| CA2613187A1 (en) | 2007-01-11 |
| MX2008000277A (es) | 2008-03-24 |
| US20070009976A1 (en) | 2007-01-11 |
| MA29730B1 (fr) | 2008-09-01 |
| IL188317A0 (en) | 2008-04-13 |
| AU2006265275A1 (en) | 2007-01-11 |
| TWI312864B (en) | 2009-08-01 |
| MY157955A (en) | 2016-08-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |