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NO20076662L - Deteksjon av et malantigen uavhengig av tilstedevaerelse eller fravaer av et korresponderende terapeutisk antistoff - Google Patents

Deteksjon av et malantigen uavhengig av tilstedevaerelse eller fravaer av et korresponderende terapeutisk antistoff

Info

Publication number
NO20076662L
NO20076662L NO20076662A NO20076662A NO20076662L NO 20076662 L NO20076662 L NO 20076662L NO 20076662 A NO20076662 A NO 20076662A NO 20076662 A NO20076662 A NO 20076662A NO 20076662 L NO20076662 L NO 20076662L
Authority
NO
Norway
Prior art keywords
therapeutic antibody
malantigen
absence
independent
detection
Prior art date
Application number
NO20076662A
Other languages
English (en)
Inventor
Helmut Lenz
Werner Scheuer
Martina Thier
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO20076662L publication Critical patent/NO20076662L/no

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Foreliggende oppfinnelse angår området terapeutiske antistoffer. Oppfinnelsen angår spesielt en metode for detektering av målantigenet av et terapeutisk antistoff i en prøve omfattende trinnene med a) tilveiebringelse av prøven som skal analyseres, b) inkubering av nevnte prøve med nevnte terapeutiske antistoff under betingelser egnet for binding av nevnte terapeutiske antistoff til nevnte målantigen, hvorved et målantigen-terapeutisk antistoff-kompleks blir dannet og c) detektering av komplekset dannet i (b).
NO20076662A 2005-07-06 2007-12-28 Deteksjon av et malantigen uavhengig av tilstedevaerelse eller fravaer av et korresponderende terapeutisk antistoff NO20076662L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05014618 2005-07-06
EP06004447 2006-03-06
PCT/EP2006/006524 WO2007003420A1 (en) 2005-07-06 2006-07-05 Detection of a target antigen irrespective of the presence or absence of a corresponding therapeutic antibody

Publications (1)

Publication Number Publication Date
NO20076662L true NO20076662L (no) 2008-04-03

Family

ID=36922121

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20076662A NO20076662L (no) 2005-07-06 2007-12-28 Deteksjon av et malantigen uavhengig av tilstedevaerelse eller fravaer av et korresponderende terapeutisk antistoff

Country Status (19)

Country Link
US (1) US20070009976A1 (no)
EP (2) EP1902315A1 (no)
JP (1) JP2008545145A (no)
KR (1) KR20080016939A (no)
AR (1) AR053948A1 (no)
AU (1) AU2006265275A1 (no)
BR (1) BRPI0612591A2 (no)
CA (1) CA2613187A1 (no)
CR (1) CR9635A (no)
EC (1) ECSP088081A (no)
IL (1) IL188317A0 (no)
MA (1) MA29730B1 (no)
MX (1) MX2008000277A (no)
MY (1) MY157955A (no)
NO (1) NO20076662L (no)
NZ (1) NZ564471A (no)
RU (1) RU2008103608A (no)
TW (1) TWI312864B (no)
WO (1) WO2007003420A1 (no)

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CA2407556C (en) * 2000-05-19 2011-06-21 Genentech, Inc. Gene detection assay for improving the likelihood of an effective response to an erbb antagonist cancer therapy
KR20140032004A (ko) * 2004-07-22 2014-03-13 제넨테크, 인크. Ｈｅｒ２ 항체 조성물
US7936392B2 (en) 2004-10-01 2011-05-03 The Board Of Trustees Of The Leland Stanford Junior University Imaging arrangements and methods therefor
JO3000B1 (ar) * 2004-10-20 2016-09-05 Genentech Inc مركبات أجسام مضادة .
US20060188509A1 (en) 2005-02-23 2006-08-24 Genentech, Inc. Extending time to disease progression or survival in cancer patients
PE20070207A1 (es) * 2005-07-22 2007-03-09 Genentech Inc Tratamiento combinado de los tumores que expresan el her
US8358354B2 (en) 2009-01-26 2013-01-22 The Board Of Trustees Of The Leland Stanford Junior University Correction of optical abberations
WO2007092581A2 (en) 2006-02-07 2007-08-16 The Board Of Trustees Of The Leland Stanford Junior University Correction of optical aberrations
PE20090681A1 (es) 2007-03-02 2009-06-10 Genentech Inc Prediccion de respuesta a un inhibidor her
TWI472339B (zh) 2008-01-30 2015-02-11 Genentech Inc 包含結合至ｈｅｒ２結構域ii之抗體及其酸性變異體的組合物
BRPI0812682A2 (pt) 2008-06-16 2010-06-22 Genentech Inc tratamento de cáncer de mama metastático
KR102099991B1 (ko) 2011-10-14 2020-04-14 제넨테크, 인크. Her2 이량체화 억제제인 페르투주맙의 용도 및 이를 포함하는 제조품
KR101327542B1 (ko) * 2012-03-15 2013-11-08 광주과학기술원 양자점 기반의 경쟁 면역분석법 및 다중 유세포 분석법을 이용한 시료 중 오염물질의 검출 방법
AU2012232949B2 (en) * 2012-09-28 2014-07-03 Willowtree Holdings Pty Ltd Temporary bulkhead
CA2907776C (en) 2013-04-16 2020-04-14 Genentech, Inc. Pertuzumab variants and evaluation thereof
EP3581586A1 (en) 2014-04-25 2019-12-18 F. Hoffmann-La Roche AG Methods of treating early breast cancer with trastuzumab-mcc-dm1 and pertuzumab
PT3302551T (pt) 2015-05-30 2024-08-21 H Hoffnabb La Roche Ag Métodos de tratamento do cancro da mama metastático positivo para her2 não tratado previamente
WO2017087280A1 (en) 2015-11-16 2017-05-26 Genentech, Inc. Methods of treating her2-positive cancer
EP3562844A1 (en) 2016-12-28 2019-11-06 Genentech, Inc. Treatment of advanced her2 expressing cancer
CA3047349C (en) 2017-01-17 2020-09-22 Genentech, Inc. Subcutaneous her2 antibody formulations
MX388169B (es) 2017-03-02 2025-03-19 Genentech Inc Pertuzumab para usarse en el tratamiento de cáncer de mama her2 positivo.
EP3615695A1 (en) 2017-04-24 2020-03-04 Genentech, Inc. Erbb2/her2 mutations in the transmebrane or juxtamembrane domain
CN115916834A (zh) 2020-06-29 2023-04-04 基因泰克公司 帕妥珠单抗加曲妥珠单抗的固定剂量组合

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2095818B (en) 1981-03-27 1985-10-02 Exxon Research Engineering Co Staged adsorption/resorption heat pump
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
WO1992022653A1 (en) * 1991-06-14 1992-12-23 Genentech, Inc. Method for making humanized antibodies
AU4025193A (en) 1992-04-08 1993-11-18 Cetus Oncology Corporation Humanized C-erbB-2 specific antibodies
WO1998017797A1 (en) 1996-10-18 1998-04-30 Genentech, Inc. ANTI-ErbB2 ANTIBODIES
AU2002327037A1 (en) * 2001-09-20 2003-04-01 Board Of Regents, The University Of Texas System Measuring circulating therapeutic antibody, antigen and antigen/antibody complexes using elisa assays
BR0312534A (pt) * 2002-07-15 2007-03-13 Genentech Inc método de identificação de um tumor, método para a identificação de células de tumor, método para prever a resposta de um indivìduo diagnosticado com um tumor de her2-positivo, método para a identificação de um individuo responsivo ao tratamento com anticorpo anti-her2 e métodos de tratamento de um paciente e artigo de manufatura

Also Published As

Publication number Publication date
MX2008000277A (es) 2008-03-24
ECSP088081A (es) 2008-02-20
WO2007003420A1 (en) 2007-01-11
BRPI0612591A2 (pt) 2010-11-23
CA2613187A1 (en) 2007-01-11
TW200741203A (en) 2007-11-01
MA29730B1 (fr) 2008-09-01
NZ564471A (en) 2010-04-30
CR9635A (es) 2008-02-20
TWI312864B (en) 2009-08-01
US20070009976A1 (en) 2007-01-11
AR053948A1 (es) 2007-05-23
EP2194380A3 (en) 2010-07-14
EP1902315A1 (en) 2008-03-26
KR20080016939A (ko) 2008-02-22
IL188317A0 (en) 2008-04-13
EP2194380A2 (en) 2010-06-09
RU2008103608A (ru) 2009-08-20
MY157955A (en) 2016-08-30
JP2008545145A (ja) 2008-12-11
AU2006265275A1 (en) 2007-01-11

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Legal Events

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