NO3034071T3 - - Google Patents
Info
- Publication number
- NO3034071T3 NO3034071T3 NO15193269A NO15193269A NO3034071T3 NO 3034071 T3 NO3034071 T3 NO 3034071T3 NO 15193269 A NO15193269 A NO 15193269A NO 15193269 A NO15193269 A NO 15193269A NO 3034071 T3 NO3034071 T3 NO 3034071T3
- Authority
- NO
- Norway
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Edible Oils And Fats (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11195015 | 2011-12-21 | ||
| EP12185714 | 2012-09-24 | ||
| EP15193269.6A EP3034071B1 (fr) | 2011-12-21 | 2012-12-19 | Nouvelle combinaison |
| EP12813324.6A EP2793866B2 (fr) | 2011-12-21 | 2012-12-19 | Comprimé bicouche comprenant du chlorhydrate de bénazépril et du pimobendane |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO3034071T3 true NO3034071T3 (fr) | 2018-05-05 |
Family
ID=47552987
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO15193269A NO3034071T3 (fr) | 2011-12-21 | 2012-12-19 |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US10874618B2 (fr) |
| EP (3) | EP2793866B2 (fr) |
| JP (1) | JP6148252B2 (fr) |
| CN (1) | CN104010632B (fr) |
| AU (1) | AU2012357795B2 (fr) |
| BR (1) | BR112014014896A2 (fr) |
| CA (1) | CA2858941C (fr) |
| CL (1) | CL2014001534A1 (fr) |
| CO (1) | CO6970601A2 (fr) |
| CY (1) | CY1117086T1 (fr) |
| DK (2) | DK3034071T3 (fr) |
| ES (2) | ES2656412T3 (fr) |
| HR (1) | HRP20151347T1 (fr) |
| HU (2) | HUE035830T2 (fr) |
| MX (1) | MX365621B (fr) |
| NO (1) | NO3034071T3 (fr) |
| PL (2) | PL2793866T5 (fr) |
| PT (1) | PT3034071T (fr) |
| RS (1) | RS54475B1 (fr) |
| RU (1) | RU2014129508A (fr) |
| SI (1) | SI2793866T1 (fr) |
| WO (1) | WO2013092673A2 (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1579862A1 (fr) | 2004-03-25 | 2005-09-28 | Boehringer Ingelheim Vetmedica Gmbh | Utilisation des inhibiteurs de PDE III pour la réduction de la taille du coeur chez des mammifères souffrant d'insufficances cardiaques |
| US8980894B2 (en) | 2004-03-25 | 2015-03-17 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure |
| EP1920785A1 (fr) | 2006-11-07 | 2008-05-14 | Boehringer Ingelheim Vetmedica Gmbh | Préparation liquide contenant un complexe du pimobendane et de la cyclodextrine |
| EP2793866B2 (fr) | 2011-12-21 | 2023-10-25 | Elanco Tiergesundheit AG | Comprimé bicouche comprenant du chlorhydrate de bénazépril et du pimobendane |
| US10398705B2 (en) | 2012-03-15 | 2019-09-03 | Boehringer Ingelheim Vetmedica Gmbh | Pharmaceutical tablet formulation for the veterinary medical sector, method of production and use thereof |
| ES2860526T3 (es) | 2013-07-19 | 2021-10-05 | Boehringer Ingelheim Vetmedica Gmbh | Derivados de ciclodextrina eterificada conservados que contienen una composición farmacéutica acuosa líquida |
| KR102308973B1 (ko) | 2013-12-04 | 2021-10-08 | 베링거잉겔하임베트메디카게엠베하 | 개선된 피모벤단의 약제학적 조성물 |
| US10537570B2 (en) | 2016-04-06 | 2020-01-21 | Boehringer Ingelheim Vetmedica Gmbh | Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease |
| CN112618505B (zh) * | 2020-12-30 | 2022-11-15 | 南京朗博特动物药业有限公司 | 一种宠物用含有贝那普利和匹莫苯丹的复方药物组合物及其制备方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5364646A (en) | 1990-01-10 | 1994-11-15 | Dr. Karl Thomae Gmbh | Oral pharmaceutical forms of pimobendan |
| US6162802A (en) | 1992-03-10 | 2000-12-19 | Papa; Joseph | Synergistic combination therapy using benazepril and amlodipine for the treatment of cardiovascular disorders and compositions therefor |
| CA2432638A1 (fr) | 2000-12-18 | 2002-06-27 | Novartis Ag | Combinaison therapeutique d'amlodipine et de benazepril |
| WO2003075842A2 (fr) | 2002-03-08 | 2003-09-18 | Teva Pharmeceuticals Usa, Inc. | Formulations stables d'inhibiteurs de l'enzyme de conversion de l'angiotensine (ace) |
| CO5400144A1 (es) * | 2002-03-11 | 2004-05-31 | Novartis Ag | Compuestos organicos |
| KR20060120126A (ko) | 2003-10-20 | 2006-11-24 | 노파르티스 아게 | 심혈관계 이환상태를 감소시키기 위한 베나제프릴 및암로디핀 |
| GB2394660A (en) | 2003-12-17 | 2004-05-05 | Niche Generics Ltd | Stabilisation of pharmaceutical compositions comprising ACE inhibitor by absence of acidic excipients having large specific surface area, eg silicon dioxide |
| DE102004011512B4 (de) * | 2004-03-08 | 2022-01-13 | Boehringer Ingelheim Vetmedica Gmbh | Pharmazeutische Zubereitung enthaltend Pimobendan |
| US8980894B2 (en) * | 2004-03-25 | 2015-03-17 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure |
| JP2005281283A (ja) | 2004-03-31 | 2005-10-13 | Akira Matsumori | ベンズイミダゾール系薬剤の併用医薬 |
| WO2006085208A2 (fr) | 2005-02-11 | 2006-08-17 | Ranbaxy Laboratories Limited | Formes galeniques solides stables d'amlodipine et de benazepril |
| JP2010500374A (ja) * | 2006-08-08 | 2010-01-07 | エーシーシーユー−ブレイク テクノロジーズ,インク. | 複数の活性セグメントを含む薬剤の錠剤 |
| PL2120878T3 (pl) | 2007-02-09 | 2015-01-30 | Alphapharm Pty Ltd | Postać dawkowania zawierająca dwa czynne składniki farmaceutyczne o różnych postaciach fizycznych |
| FR2917975B1 (fr) * | 2007-06-26 | 2009-10-16 | Ceva Sante Animale Sa | Compositions et traitement de l'insuffisance cardiaque chez les animaux mammiferes non humains |
| WO2010055119A2 (fr) | 2008-11-17 | 2010-05-20 | Novartis Ag | Composition pharmaceutique comprenant du pimobendane |
| WO2010097501A2 (fr) | 2009-02-26 | 2010-09-02 | Orion Corporation | Traitement combiné |
| WO2011111066A2 (fr) | 2010-03-12 | 2011-09-15 | Connexios Life Sciences Pvt. Ltd. | Composition et ses utilisations |
| EP2793866B2 (fr) | 2011-12-21 | 2023-10-25 | Elanco Tiergesundheit AG | Comprimé bicouche comprenant du chlorhydrate de bénazépril et du pimobendane |
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2012
- 2012-12-19 EP EP12813324.6A patent/EP2793866B2/fr active Active
- 2012-12-19 CN CN201280062716.3A patent/CN104010632B/zh active Active
- 2012-12-19 ES ES15193269.6T patent/ES2656412T3/es active Active
- 2012-12-19 WO PCT/EP2012/076100 patent/WO2013092673A2/fr not_active Ceased
- 2012-12-19 ES ES12813324T patent/ES2560052T5/es active Active
- 2012-12-19 PT PT151932696T patent/PT3034071T/pt unknown
- 2012-12-19 PL PL12813324.6T patent/PL2793866T5/pl unknown
- 2012-12-19 AU AU2012357795A patent/AU2012357795B2/en active Active
- 2012-12-19 HU HUE15193269A patent/HUE035830T2/en unknown
- 2012-12-19 HR HRP20151347TT patent/HRP20151347T1/hr unknown
- 2012-12-19 CA CA2858941A patent/CA2858941C/fr active Active
- 2012-12-19 JP JP2014547959A patent/JP6148252B2/ja active Active
- 2012-12-19 EP EP15193269.6A patent/EP3034071B1/fr active Active
- 2012-12-19 DK DK15193269.6T patent/DK3034071T3/en active
- 2012-12-19 MX MX2014007700A patent/MX365621B/es active IP Right Grant
- 2012-12-19 NO NO15193269A patent/NO3034071T3/no unknown
- 2012-12-19 PL PL15193269T patent/PL3034071T3/pl unknown
- 2012-12-19 US US14/366,900 patent/US10874618B2/en active Active
- 2012-12-19 RS RS20150850A patent/RS54475B1/sr unknown
- 2012-12-19 EP EP17199031.0A patent/EP3320894A1/fr not_active Withdrawn
- 2012-12-19 HU HUE12813324A patent/HUE028579T2/en unknown
- 2012-12-19 SI SI201230374T patent/SI2793866T1/sl unknown
- 2012-12-19 DK DK12813324.6T patent/DK2793866T4/da active
- 2012-12-19 BR BR112014014896A patent/BR112014014896A2/pt active Search and Examination
- 2012-12-19 RU RU2014129508A patent/RU2014129508A/ru unknown
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2014
- 2014-06-03 CO CO14118785A patent/CO6970601A2/es active IP Right Grant
- 2014-06-11 CL CL2014001534A patent/CL2014001534A1/es unknown
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2015
- 2015-12-30 CY CY20151101200T patent/CY1117086T1/el unknown