NO20111199A1 - Indolderivater som antikreftmidler - Google Patents

Indolderivater som antikreftmidler Download PDF

Info

Publication number: NO20111199A1
Authority: NO; Norway
Prior art keywords: formula; compound; compounds; solvent; treatment
Prior art date: 2009-02-04

Application number

NO20111199A

Other languages

English (en)

Norwegian (no)

Inventor

Bruno Schoentjes

Sophie Descamps

Nathalie Claudie Isabelle Amblard

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-02-04

Filing date

2011-09-02

Publication date

2011-11-04

2011-09-02 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2011-11-04 Publication of NO20111199A1 publication Critical patent/NO20111199A1/no

Links

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Classifications

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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings

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Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
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Veterinary Medicine (AREA)
Public Health (AREA)
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Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Immunology (AREA)
Neurology (AREA)
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Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
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Obesity (AREA)
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Emergency Medicine (AREA)
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Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

NO20111199A 2009-02-04 2011-09-02 Indolderivater som antikreftmidler NO20111199A1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP09152089		2009-02-04
PCT/EP2010/051316 WO2010089327A2 (fr)	2009-02-04	2010-02-03	Dérivés d'indole en tant qu'agents anti-cancéreux

Publications (1)

Publication Number	Publication Date
NO20111199A1 true NO20111199A1 (no)	2011-11-04

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US (1)	US8541442B2 (fr)
EP (1)	EP2393801B1 (fr)
JP (1)	JP5612611B2 (fr)
KR (1)	KR101730407B1 (fr)
CN (1)	CN102307868B (fr)
AR (1)	AR075235A1 (fr)
AU (1)	AU2010210178B2 (fr)
BR (1)	BRPI1008855B8 (fr)
CA (1)	CA2749209C (fr)
CL (1)	CL2011001860A1 (fr)
CO (1)	CO6341625A2 (fr)
EA (1)	EA021883B1 (fr)
ES (1)	ES2639752T3 (fr)
IL (1)	IL214427A (fr)
MX (1)	MX2011008195A (fr)
MY (1)	MY152018A (fr)
NO (1)	NO20111199A1 (fr)
NZ (1)	NZ594186A (fr)
SG (1)	SG173495A1 (fr)
TW (1)	TWI476189B (fr)
UA (1)	UA107455C2 (fr)
WO (1)	WO2010089327A2 (fr)
ZA (1)	ZA201105695B (fr)

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CN113480530A (zh)	2016-12-26	2021-10-08	阿里根公司	芳香烃受体调节剂
CN106632303A (zh) *	2017-01-09	2017-05-10	湖南华腾制药有限公司	一种6‑噻唑基吲哚衍生物的制备方法
EP3713937A2 (fr)	2017-11-20	2020-09-30	Ariagen, Inc.	Composés d'indole et leur utilisation
CN108659003B (zh) *	2018-04-14	2021-01-26	上海朝晖药业有限公司	一种治疗口腔溃疡的化合物的制备方法
MX2021007970A (es) *	2019-01-04	2021-08-16	Jiangsu Hengrui Medicine Co	Derivado de 6-oxo-1,6-dihidropiridazina, metodo de preparacion del mismo y uso medico del mismo.
TW202102480A (zh) *	2019-02-20	2021-01-16	大陸商江蘇恆瑞醫藥股份有限公司	６－側氧基－１，６－二氫噠嗪類前藥衍生物、其製備方法及其在醫藥上的應用
WO2020214740A1 (fr)	2019-04-15	2020-10-22	Ariagen, Inc.	Composés d'indole chiraux et leur utilisation
WO2024102758A2 (fr) *	2022-11-08	2024-05-16	The General Hospital Corporation	Séries n-(n-aminoalkyl)phénanthridiunium de fluorophores sensibles au chlorure et leurs procédés d'utilisation

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AUPO863197A0 (en)	1997-08-18	1997-09-11	Fujisawa Pharmaceutical Co., Ltd.	Novel derivatives
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UA71587C2 (uk)	1998-11-10	2004-12-15	Шерінг Акцієнгезелльшафт	Аміди антранілової кислоти та їхнє застосування як лікарських засобів
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WO2001042224A1 (fr)	1999-12-09	2001-06-14	Mitsubishi Pharma Corporation	Derives carboxyamido
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AU2002357728A1 (en)	2001-11-09	2003-05-19	The Regents Of The University Of California	Alpha-helix mimicry by a class of organic molecules
DK1443937T3 (da)	2001-11-13	2008-10-20	Ortho Mcneil Pharm Inc	Substituerede 1,4-benzodiazepiner samt deres anvendelse til behnadling af cancer
RU2305095C2 (ru)	2001-12-18	2007-08-27	Ф.Хоффманн-Ля Рош Аг	Цис-2,4,5-трифенилимидазолины и фармацевтическая композиция на их основе
GB0215650D0 (en)	2002-07-05	2002-08-14	Cyclacel Ltd	Bisarylsufonamide compounds
DK1809622T3 (da) *	2004-09-22	2010-11-08	Janssen Pharmaceutica Nv	Inhibitorer af interaktionen mellem MDM2 og P53
EP2001868B1 (fr)	2006-03-22	2013-07-17	Janssen Pharmaceutica N.V.	Inhibiteurs de l'interaction entre mdm2 et p53
ATE470665T1 (de)	2006-03-22	2010-06-15	Janssen Pharmaceutica Nv	Cycloalkylaminderivate als inhibitoren der wechselwirkung zwischen mdm2 und p53
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JO2704B1 (en)	2007-09-21	2013-03-03	جانسين فارماسوتيكا ان في	Interference inhibition factors between MD2 and B53
AU2008300483B2 (en)	2007-09-21	2013-01-10	Janssen Pharmaceutica Nv	Inhibitors of the interaction between MDM2 and p53

2010
- 2010-02-03 AU AU2010210178A patent/AU2010210178B2/en not_active Ceased
- 2010-02-03 JP JP2011548674A patent/JP5612611B2/ja not_active Expired - Fee Related
- 2010-02-03 AR ARP100100298A patent/AR075235A1/es unknown
- 2010-02-03 EA EA201170997A patent/EA021883B1/ru not_active IP Right Cessation
- 2010-02-03 CN CN201080007001.9A patent/CN102307868B/zh not_active Expired - Fee Related
- 2010-02-03 SG SG2011055431A patent/SG173495A1/en unknown
- 2010-02-03 ES ES10702310.3T patent/ES2639752T3/es active Active
- 2010-02-03 KR KR1020117020348A patent/KR101730407B1/ko not_active Expired - Fee Related
- 2010-02-03 EP EP10702310.3A patent/EP2393801B1/fr active Active
- 2010-02-03 WO PCT/EP2010/051316 patent/WO2010089327A2/fr not_active Ceased
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- 2010-02-03 MY MYPI2011003583 patent/MY152018A/en unknown
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- 2010-02-03 MX MX2011008195A patent/MX2011008195A/es active IP Right Grant
- 2010-02-03 US US13/147,707 patent/US8541442B2/en not_active Expired - Fee Related
- 2010-02-03 CA CA2749209A patent/CA2749209C/fr active Active
- 2010-02-03 NZ NZ594186A patent/NZ594186A/xx not_active IP Right Cessation
- 2010-03-02 UA UAA201109449A patent/UA107455C2/uk unknown
2011
- 2011-07-12 CO CO11087033A patent/CO6341625A2/es not_active Application Discontinuation
- 2011-08-02 CL CL2011001860A patent/CL2011001860A1/es unknown
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- 2011-08-03 IL IL214427A patent/IL214427A/en active IP Right Grant
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Also Published As

Publication number	Publication date
TWI476189B (zh)	2015-03-11
CN102307868A (zh)	2012-01-04
CN102307868B (zh)	2016-06-22
AU2010210178A1 (en)	2011-07-28
MX2011008195A (es)	2011-09-06
US20110294846A1 (en)	2011-12-01
ES2639752T3 (es)	2017-10-30
CL2011001860A1 (es)	2012-07-20
BRPI1008855B1 (pt)	2020-05-12
SG173495A1 (en)	2011-09-29
CA2749209C (fr)	2017-01-10
UA107455C2 (uk)	2015-01-12
EA201170997A1 (ru)	2012-01-30
MY152018A (en)	2014-08-15
EP2393801A2 (fr)	2011-12-14
JP2012516872A (ja)	2012-07-26
IL214427A0 (en)	2011-09-27
US8541442B2 (en)	2013-09-24
KR101730407B1 (ko)	2017-04-26
BRPI1008855A2 (pt)	2016-03-15
TW201038552A (en)	2010-11-01
CO6341625A2 (es)	2011-11-21
KR20110116195A (ko)	2011-10-25
AR075235A1 (es)	2011-03-16
AU2010210178B2 (en)	2014-06-05
BRPI1008855B8 (pt)	2021-05-25
CA2749209A1 (fr)	2010-08-12
WO2010089327A2 (fr)	2010-08-12
WO2010089327A3 (fr)	2010-10-21
NZ594186A (en)	2012-12-21
IL214427A (en)	2016-02-29
JP5612611B2 (ja)	2014-10-22
EP2393801B1 (fr)	2017-07-12
ZA201105695B (en)	2014-01-29
EA021883B1 (ru)	2015-09-30

Publication	Publication Date	Title
NO20111199A1 (no)	2011-11-04	Indolderivater som antikreftmidler
CA2783624C (fr)	2019-08-20	Composes heteroaryle et utilisations associees
EP2953943B1 (fr)	2017-04-12	Dihydropyrimidinones bicycliques substituées et leur utilisation à titre d'inhibiteurs de l'activité élastase neutrophile
RU2477724C2 (ru)	2013-03-20	Ингибиторы взаимодействия между mdm2 и p53
EP2964617B1 (fr)	2017-04-12	Dihydropyrimidinones bicycliques substituées et leur utilisation en tant qu'inhibiteurs de l'activité élastase de neutrophiles
RS51007B (sr)	2010-10-31	Supstituisani piridinil i pirimidinil derivati kao modulatori metabolizma i lečenje poremećaja proisteklih iz toga
JP2017509687A (ja)	2017-04-06	大環状ピリミジン誘導体
EP3019493A1 (fr)	2016-05-18	Dihydroquinoxalinones et dihydropyridopyrazinones inhibitrices de protéine bet modifiées
WO2009019274A1 (fr)	2009-02-12	Phénylènediamines substituées utilisables en tant qu'inhibiteurs de l'interaction entre mdm2 et p53
EP3174876B1 (fr)	2019-12-18	Dihydropyrimidinones bicycliques substituées et leur utilisation en tant qu'inhibiteurs de l'activité de l'élastase neutrophile
JP6457523B2 (ja)	2019-01-23	医薬組成物のためのスルホキシイミン置換キナゾリン
HK1163674B (en)	2017-09-29	Indole derivatives as anticancer agents
HK1163674A (en)	2012-09-14	Indole derivatives as anticancer agents
TW202128653A (zh)	2021-08-01	作為parp7抑制劑的嗒酮

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