[go: up one dir, main page]

NO20090346L - Pyrazolderivater som inhibitorer av cytokrom P450 - Google Patents

Pyrazolderivater som inhibitorer av cytokrom P450

Info

Publication number
NO20090346L
NO20090346L NO20090346A NO20090346A NO20090346L NO 20090346 L NO20090346 L NO 20090346L NO 20090346 A NO20090346 A NO 20090346A NO 20090346 A NO20090346 A NO 20090346A NO 20090346 L NO20090346 L NO 20090346L
Authority
NO
Norway
Prior art keywords
cytochrome
inhibitors
pyrazole derivatives
processes
solvates
Prior art date
Application number
NO20090346A
Other languages
English (en)
Norwegian (no)
Inventor
Simon Paul Planken
Scott Channing Sutton
Rongliang Chen
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of NO20090346L publication Critical patent/NO20090346L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO20090346A 2006-07-05 2009-01-22 Pyrazolderivater som inhibitorer av cytokrom P450 NO20090346L (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US80659606P 2006-07-05 2006-07-05
US91098807P 2007-04-10 2007-04-10
US94180807P 2007-06-04 2007-06-04
PCT/IB2007/001878 WO2008004096A1 (fr) 2006-07-05 2007-06-25 Dérivés de pyrazole utilisés en tant qu'inhibiteurs du cytochrome p450

Publications (1)

Publication Number Publication Date
NO20090346L true NO20090346L (no) 2009-02-19

Family

ID=38515807

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20090346A NO20090346L (no) 2006-07-05 2009-01-22 Pyrazolderivater som inhibitorer av cytokrom P450

Country Status (24)

Country Link
US (1) US7919488B2 (fr)
EP (1) EP2046774A1 (fr)
KR (1) KR20090034958A (fr)
CN (1) CN101511812A (fr)
AP (1) AP2009004763A0 (fr)
AR (1) AR062154A1 (fr)
AU (1) AU2007270814B2 (fr)
CA (1) CA2660031A1 (fr)
CO (1) CO6150178A2 (fr)
CR (1) CR10573A (fr)
EA (1) EA200900135A1 (fr)
GT (1) GT200700053A (fr)
IL (1) IL196490A0 (fr)
MA (1) MA30629B1 (fr)
MX (1) MX2009000482A (fr)
NO (1) NO20090346L (fr)
NZ (1) NZ574207A (fr)
PE (1) PE20080998A1 (fr)
RS (1) RS20090036A (fr)
TN (1) TN2009000033A1 (fr)
TW (1) TWI334867B (fr)
UY (1) UY30460A1 (fr)
WO (1) WO2008004096A1 (fr)
ZA (1) ZA200900478B (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010510224A (ja) * 2006-11-17 2010-04-02 アボット・ラボラトリーズ ケモカイン受容体拮抗薬としてのアミノピロリジン類
JP2010521456A (ja) * 2007-03-13 2010-06-24 アレテ セラピューティクス， インコーポレイテッド 可溶性エポキシドヒドロラーゼ阻害剤
JP2011512359A (ja) 2008-02-14 2011-04-21 アミラ ファーマシューティカルズ，インク． プロスタグランジンｄ２受容体のアンタゴニストとしての環式ジアリールエーテル化合物
JP2011518130A (ja) 2008-04-02 2011-06-23 アミラ ファーマシューティカルズ，インク． プロスタグランジンｄ２受容体のアミノアルキルフェニルアンタゴニスト
DE102009041241A1 (de) 2009-09-11 2011-08-04 Bayer Schering Pharma Aktiengesellschaft, 13353 Substituierte Aryl-Verbindungen und ihre Verwendung
DE102008057344A1 (de) 2008-11-14 2010-05-20 Bayer Schering Pharma Aktiengesellschaft Aminoalkyl-substituierte Aryl-Verbindungen und ihre Verwendung
DE102008057364A1 (de) 2008-11-14 2010-05-20 Bayer Schering Pharma Aktiengesellschaft Substituierte Aryl-Verbindungen und ihre Verwendung
DE102008057343A1 (de) 2008-11-14 2010-05-20 Bayer Schering Pharma Aktiengesellschaft Heterocyclisch substituierte Aryl-Verbindungen und ihre Verwendung
DE102009041242A1 (de) 2009-09-11 2011-12-15 Bayer Schering Pharma Aktiengesellschaft Heterocyclisch substituierte Aryl-Verbindungen und ihre Verwendung
US8383654B2 (en) 2008-11-17 2013-02-26 Panmira Pharmaceuticals, Llc Heterocyclic antagonists of prostaglandin D2 receptors
CN103313976B (zh) 2010-06-30 2016-11-23 铁木医药有限公司 sGC刺激物
US9061030B2 (en) 2010-11-09 2015-06-23 Ironwood Pharmaceuticals, Inc. sGC stimulators
CA2861804C (fr) 2011-12-27 2021-10-26 Ironwood Pharmaceuticals, Inc. Pyrazoles 2-benzyle, 3-(pyrimidin-2-yle)-substitues utiles comme stimulateurs de scg
WO2014000178A1 (fr) 2012-06-27 2014-01-03 Merck Sharp & Dohme Corp. Dérivés de sulfamide et leurs méthodes d'utilisation permettant d'améliorer la pharmacocinétique d'un médicament
CN104540813A (zh) * 2012-06-27 2015-04-22 默沙东公司 磺酰胺衍生物以及使用它们用于改善药物的药物动力学的方法
WO2014194519A1 (fr) 2013-06-07 2014-12-11 Merck Sharp & Dohme Corp. Dérivés imidazole et leurs procédés d'utilisation pour l'amélioration des propriétés pharmacocinétiques d'un médicament
WO2015070366A1 (fr) * 2013-11-12 2015-05-21 Merck Sharp & Dohme Corp. Dérivés d'imidazole et de triazole liés à aryle et leurs procédés d'utilisation pour améliorer la pharmacocinétique d'un médicament
WO2015070367A1 (fr) 2013-11-12 2015-05-21 Merck Sharp & Dohme Corp. Dérivés d'imidazole et de triazole liés à la pipéridine ou la pipérazine et leurs procédés d'utilisation pour améliorer la pharmacocinétique d'un médicament
WO2020163689A1 (fr) * 2019-02-08 2020-08-13 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Inhibiteurs de formation de 20-hete

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0024795D0 (en) * 2000-10-10 2000-11-22 Hoffmann La Roche Pyrazole derivatives for the treatment of viral diseases
CA2439593C (fr) * 2001-04-05 2010-02-09 Torrent Pharmaceuticals Ltd. Composes heterocycliques pour des complications vasculaires diabetiques et liees au vieillissement
US7008953B2 (en) * 2003-07-30 2006-03-07 Agouron Pharmaceuticals, Inc. 3, 5 Disubstituted indazole compounds, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation
US7662844B2 (en) * 2004-07-12 2010-02-16 Osi Pharmaceuticals, Inc. Naphthylene derivatives as cytochrome P450 inhibitors
KR100975448B1 (ko) * 2005-09-23 2010-08-11 화이자 프로덕츠 인크. 시토크롬 ｐ４５０ ３ａ４ （ｃｙｐ３ａ４） 억제제로서의피리딘아미노술포닐 치환된 벤즈아미드

Also Published As

Publication number Publication date
GT200700053A (es) 2009-08-03
MX2009000482A (es) 2009-01-27
CN101511812A (zh) 2009-08-19
AP2009004763A0 (en) 2009-02-28
US20080021011A1 (en) 2008-01-24
CA2660031A1 (fr) 2008-01-10
UY30460A1 (es) 2008-02-29
KR20090034958A (ko) 2009-04-08
AU2007270814A1 (en) 2008-01-10
WO2008004096A1 (fr) 2008-01-10
IL196490A0 (en) 2011-07-31
AR062154A1 (es) 2008-10-22
ZA200900478B (en) 2010-04-28
US7919488B2 (en) 2011-04-05
AU2007270814B2 (en) 2011-07-14
TN2009000033A1 (fr) 2010-08-19
EA200900135A1 (ru) 2009-06-30
RS20090036A (sr) 2010-06-30
CR10573A (es) 2009-02-12
PE20080998A1 (es) 2008-08-15
CO6150178A2 (es) 2010-04-20
NZ574207A (en) 2010-10-29
EP2046774A1 (fr) 2009-04-15
MA30629B1 (fr) 2009-08-03
TWI334867B (en) 2010-12-21
TW200811159A (en) 2008-03-01

Similar Documents

Publication Publication Date Title
NO20090346L (no) Pyrazolderivater som inhibitorer av cytokrom P450
WO2007087548A3 (fr) Composés chimiques
NO20090628L (no) Pyridizinon derivativater
NO20081554L (no) Isoindollmidforbindelser og sammensetninger omfattende samme, og anvendelse derav
IL189666A0 (en) Pyridinaminosulfonyl substituted benzamides as inhibitors of cytochrome p450 3a4 (cyp3a4)
NO20091893L (no) Nye 1,4-benzotiepin-1,1-dioksidderivater som er substituert med benzylgrupper, fremgangsmater for fremstilling av medisiner inneholdende forbindelsene og anvendelse derav.
NO20090295L (no) Substituerte heteroarylderivater
NO20066055L (no) Pyridinderivater
MX2009003038A (es) Derivados de quinazolinona 5-sustituidos como agentes antitumorales.
NO20083863L (no) Pyrazoler som 11-beta-hsd-1
NO20092723L (no) Indazolylester og amidderivater for behandling av gluccocorticoid reseptormedierte sykdommer
NO20074703L (no) Antibakterielle piperidinderivater
MX2009008540A (es) Inhibidores de virus de hepatitis c macrociclicos sustituidos con pirimidina.
PL1899329T3 (pl) Pirymidyno-podstawione pochodne benzimidazolu jako inhibitory kinaz białkowych
NO20083246L (no) Nye benzimidazolderivater som vanilloid-reseptor 1 (VRL) inhibitorer
NO20082256L (no) Pyrazolderivater, preparater som inneholder slike forbindelser, og fremgangsmåter for anvendelse
NO20092058L (no) Heteroaryl pyrrolidinyl ketonderivater
WO2009105969A8 (fr) Analogues d'épothilone, leurs compositions pharmaceutiques, leur utilisation et leurs préparations
NO20084543L (no) Benzimidazolderivater
NO20080035L (no) Benzooksazol-2-on derivater som lipase og fosfolipaseinhibitorer
NO20080110L (no) Benzimidazolderivativer som 5-HT6,5-HT24
UA90285C2 (ru) Производные гидантоина, полезные как ингибиторы металлопротеиназ
WO2008004100A9 (fr) Composés thérapeutiques
WO2008039894A3 (fr) Compositions pharmaceutiques d'atorvastatine
MY142817A (en) New naphthalene derivatives, method of preparing same and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application