[go: up one dir, main page]

NO20074703L - Antibakterielle piperidinderivater - Google Patents

Antibakterielle piperidinderivater

Info

Publication number
NO20074703L
NO20074703L NO20074703A NO20074703A NO20074703L NO 20074703 L NO20074703 L NO 20074703L NO 20074703 A NO20074703 A NO 20074703A NO 20074703 A NO20074703 A NO 20074703A NO 20074703 L NO20074703 L NO 20074703L
Authority
NO
Norway
Prior art keywords
antibacterial
piperidine derivatives
drugs
compounds
formula
Prior art date
Application number
NO20074703A
Other languages
English (en)
Inventor
George Mullen
Michael Barry Gravestock
Sheila Irene Hauck
Fei Zhou
Paul Robert Fleming
Kenneth Gregory Hull
Greg Basarab
Brian Dangel
Oluyinka Green
Pamela Hill
Brian Sherer
Haihong Ni
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36218455&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20074703(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20074703L publication Critical patent/NO20074703L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/541Non-condensed thiazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Forbindelser med formel (I) og farmasøytisk akseptable salter av dem blir beskrevet. Fremgangsmåter for fremstilling av dem, farmasøytiske preparater som inneholder dem, anvendelse av dem som legemidler og anvendelse av dem ved behandling av bakterielle infeksjoner beskrives også.
NO20074703A 2005-02-18 2007-09-14 Antibakterielle piperidinderivater NO20074703L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65467005P 2005-02-18 2005-02-18
PCT/GB2006/000529 WO2006087543A1 (en) 2005-02-18 2006-02-16 Antibacterial piperidine derivatives

Publications (1)

Publication Number Publication Date
NO20074703L true NO20074703L (no) 2007-11-14

Family

ID=36218455

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20074703A NO20074703L (no) 2005-02-18 2007-09-14 Antibakterielle piperidinderivater

Country Status (21)

Country Link
US (2) US8399489B2 (no)
EP (1) EP1853586B1 (no)
JP (4) JP4058106B2 (no)
KR (2) KR20070113233A (no)
CN (1) CN101163693B (no)
AR (1) AR053683A1 (no)
AU (1) AU2006215399B2 (no)
BR (1) BRPI0607756A2 (no)
CA (1) CA2598423C (no)
ES (1) ES2430569T3 (no)
IL (1) IL185306A (no)
MX (1) MX2007010072A (no)
NO (1) NO20074703L (no)
NZ (1) NZ561613A (no)
RU (1) RU2424240C2 (no)
SA (1) SA06270020B1 (no)
TW (1) TWI402263B (no)
UA (1) UA94901C2 (no)
UY (1) UY29384A1 (no)
WO (1) WO2006087543A1 (no)
ZA (1) ZA200706920B (no)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200526626A (en) 2003-09-13 2005-08-16 Astrazeneca Ab Chemical compounds
EP1853586B1 (en) * 2005-02-18 2013-07-24 AstraZeneca AB Antibacterial piperidine derivatives
JP2008531673A (ja) * 2005-03-04 2008-08-14 アストラゼネカ アクチボラグ 抗菌活性をもつアゼチジン及びピロールの三環式誘導体
MY150958A (en) 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
WO2008020229A2 (en) * 2006-08-17 2008-02-21 Astrazeneca Ab Antibacterial pyrrolecarboxamides
WO2008020227A2 (en) * 2006-08-17 2008-02-21 Astrazeneca Ab Antibacterial pyrrolecarboxamides
TW200819437A (en) * 2006-08-17 2008-05-01 Astrazeneca Ab Chemical compounds
JP5287253B2 (ja) 2007-01-12 2013-09-11 アステラス製薬株式会社 縮合ピリジン化合物
TW200906412A (en) * 2007-06-12 2009-02-16 Astrazeneca Ab Piperidine compounds and uses thereof
AU2008341953B2 (en) * 2007-12-26 2013-05-02 Msd K.K. Sulfonyl substituted 6-membered ring derivative
TWI498115B (zh) 2007-12-27 2015-09-01 Daiichi Sankyo Co Ltd 咪唑羰基化合物
CA2732618A1 (en) * 2008-07-30 2010-02-04 Ranbaxy Laboratories Limited Pyrrole carboxylic acid derivatives as antibacterial agents
CA3041868C (en) * 2008-10-09 2023-03-07 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Bis sulfonamide piperazinyl and piperidinyl activators of human pyruvatekinase
US8071605B2 (en) 2008-12-12 2011-12-06 Astrazeneca Ab Piperidine compounds for use in the treatment of bacterial infections
TW201026694A (en) * 2008-12-12 2010-07-16 Astrazeneca Ab Compound 468
MA32975B1 (fr) * 2008-12-22 2012-01-02 Chemocentryx Inc Antagonistes de c5ar
JP5756457B2 (ja) 2009-04-06 2015-07-29 アジオス ファーマシューティカルズ, インコーポレイテッド ピルビン酸キナーゼm2調節剤、治療組成物および関連する使用方法
CA2760929C (en) 2009-05-04 2018-01-02 Agios Pharmaceuticals, Inc. Pkm2 activators for use in the treatment of cancer
TW201102065A (en) 2009-05-29 2011-01-16 Astrazeneca Ab Heterocyclic urea derivatives and methods of use thereof
EP2448581B1 (en) 2009-06-29 2016-12-07 Agios Pharmaceuticals, Inc. Therapeutic compositions and related methods of use
SG177434A1 (en) 2009-06-29 2012-02-28 Agios Pharmaceuticals Inc Therapeutic compounds and compositions
UY32856A (es) 2009-08-26 2011-03-31 Astrazeneca Ab Derivados heterocíclicos de urea y métodos de uso de los mismos
CA2797694A1 (en) 2010-04-29 2011-11-03 The United States Of America, As Represented By The Secretary, Departmen T Of Health And Human Services Activators of human pyruvate kinase
SI2585064T1 (sl) 2010-06-24 2017-08-31 Chemocentryx, Inc. Antagonisti C5AR
US20130296363A1 (en) 2010-09-01 2013-11-07 Ambit Biosciences Corporation Quinoline and isoquinoline derivatives for use as jak modulators
WO2012083246A1 (en) 2010-12-17 2012-06-21 Agios Pharmaceuticals, Inc. Novel n- (4- (azetidine - 1 - carbonyl) phenyl) - (hetero - ) arylsulfonamide derivatives as pyruvate kinase m2 (pmk2) modulators
MX336022B (es) 2010-12-21 2016-01-06 Agios Pharmaceuticals Inc Activadores de pkm2 bicíclicos.
TWI549947B (zh) 2010-12-29 2016-09-21 阿吉歐斯製藥公司 治療化合物及組成物
EP2511263A1 (en) 2011-04-14 2012-10-17 Phenex Pharmaceuticals AG Pyrrolo sulfonamide compounds for modulation of orphan nuclear receptor RAR-related orphan receptor-gamma (RORgamma, NR1F3) activity and for the treatment of chronic inflammatory and autoimmune diseases
US20140034880A1 (en) 2011-04-18 2014-02-06 Merck Patent Gmbh Conjugated polymers
PT2704721T (pt) 2011-05-03 2018-06-14 Agios Pharmaceuticals Inc Ativadores da piruvato-cinase para utilização em terapia
WO2013084241A1 (en) * 2011-12-09 2013-06-13 Cadila Healthcare Limited Compounds as inhibitors of renin
AU2013216354B2 (en) * 2012-02-02 2017-08-31 Idorsia Pharmaceuticals Ltd 4-(benzoimidazol-2-yl)-thiazole compounds and related aza derivatives
CN105658649B (zh) * 2013-07-22 2019-03-22 爱杜西亚药品有限公司 1-(哌嗪-1-基)-2-([1,2,4]三唑-1-基)-乙酮衍生物
WO2016014927A2 (en) 2014-07-24 2016-01-28 W.R. Grace & Co.-Conn. Crystalline form of nicotinamide riboside
CN113121415B (zh) 2014-09-29 2025-09-02 凯莫森特里克斯股份有限公司 制备C5aR拮抗剂的方法和中间体
CN107428791B (zh) 2015-03-09 2024-05-28 格雷斯公司 烟酰胺核苷的结晶形式
SI3307271T1 (sl) 2015-06-11 2023-11-30 Agios Pharmaceuticals, Inc. Postopki za uporabo aktivatorjev piruvat kinaze
CN105067814A (zh) * 2015-07-24 2015-11-18 中国科学院成都生物研究所 解旋酶水解atp活性测定方法
BR112018006276A2 (pt) 2015-09-30 2018-10-16 Daiichi Sankyo Company, Limited composto, composição farmacêutica, e, inibidor de subunidade gyrb da dna girase e/ou subunidade pare de topoisomerase iv.
CN108601790A (zh) 2016-01-14 2018-09-28 凯莫森特里克斯股份有限公司 C3肾小球病的治疗方法
SI3798217T1 (sl) 2016-07-28 2023-05-31 Idorsia Pharmaceuticals Ltd Piperidinski modulatorji cxcr7 receptorja
CA3056571C (en) 2017-03-14 2021-11-23 Daiichi Sankyo Company, Limited N-phosphonoxymethyl prodrugs of hydroxyalkyl thiadiazole derivatives
EP3604281A4 (en) 2017-03-24 2020-08-19 Taisho Pharmaceutical Co., Ltd. 2(1h)-quinolinone derivative
WO2019126482A1 (en) 2017-12-22 2019-06-27 Elysium Health, Inc. Crystalline forms of nicotinamide riboside chloride
RS65594B1 (sr) 2018-01-26 2024-06-28 Idorsia Pharmaceuticals Ltd Kristalni oblici antagonista cxcr7 receptora (1-pirimidin-2-il-ciklopropil)-amida (3s,4s)-1-ciklopropilmetil-4-{[5-(2,4-difluoro-fenil)-izoksazol-3-karbonil]-amino}-piperidin-3-karboksilne kiseline
WO2020048949A1 (en) 2018-09-03 2020-03-12 Univerza V Ljubljani New class of dna gyrase and/or topoisomerase iv inhibitors with activity against gram-positive and gram-negative bacteria
US20250002455A1 (en) 2020-12-17 2025-01-02 Univerza V Ljubljani New n-phenylpyrrolamide inhibitors of dna gyrase and topoisomerase iv with antibacterial activity
CN115466246B (zh) * 2021-06-11 2024-02-06 中国医学科学院药物研究所 吡咯酰哌啶胺类化合物及其用途
CN115612309B (zh) * 2022-10-14 2023-07-21 浙江博澳新材料股份有限公司 一种双杂环双酯基偶氮分散染料及其制备方法

Family Cites Families (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL23847A (en) 1964-08-07 1969-02-27 Merck & Co Inc Benzimidazoles useful as antifungals
US4046775A (en) 1973-04-11 1977-09-06 Sterling Drug Inc. 4,5-Dihalopyrrole-2-carboxamides
US3963480A (en) 1973-04-11 1976-06-15 Sterling Drug Inc. Herbicidal pyrrole-2-carboxamides
US4912109A (en) 1987-02-02 1990-03-27 Boc, Inc. N-heterocyclic-N-(4-piperidinyl) amides and pharmaceutical compositions and methods employing such compounds
US4791112A (en) 1987-02-02 1988-12-13 The Boc Group, Inc. N-heterocyclic-N-(4-piperidyl)amides and pharmaceutical compositions and methods employing such compounds
US5739135A (en) 1993-09-03 1998-04-14 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
FR2764889B1 (fr) * 1997-06-20 2000-09-01 Sod Conseils Rech Applic Nouveaux derives du 2-(iminomethyl)amino-phenyle, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant
FR2766488B1 (fr) 1997-07-23 2000-02-18 Hoechst Marion Roussel Inc Nouveaux derives aromatiques substitues par un ribose, leur procede de preparation et leur application comme medicaments
WO2000043383A1 (en) * 1999-01-20 2000-07-27 Smithkline Beecham P.L.C. Piperidinylquinolines as protein tyrosine kinase inhibitors
US7629360B2 (en) * 1999-05-07 2009-12-08 Celgene Corporation Methods for the treatment of cachexia and graft v. host disease
JP2003104971A (ja) 1999-08-12 2003-04-09 Wakunaga Pharmaceut Co Ltd 新規アニリド誘導体又はその塩及びこれを含有する医薬
EA005680B1 (ru) 2000-01-18 2005-04-28 Вертекс Фармасьютикалз Инкорпорейтед Ингибиторы гиразы и их применение для лечения бактериальной инфекции
AU2001232809A1 (en) 2000-01-18 2001-07-31 Vertex Pharmaceuticals Incorporated Gyrase inhibitors and uses thereof
TWI284639B (en) 2000-01-24 2007-08-01 Shionogi & Co A compound having thrombopoietin receptor agonistic effect
US6900232B2 (en) 2000-06-15 2005-05-31 Pharmacia Corporation Cycloalkyl alkanoic acids as integrin receptor antagonists
US6964966B2 (en) 2001-04-25 2005-11-15 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
DOP2002000386A (es) 2001-05-30 2002-12-15 Warner Lambert Co Agentes antibacterianos
BR0211810A (pt) 2001-08-09 2004-08-24 Ono Pharmaceutical Co Derivados ácido carboxìlico e agente farmacêutico compreendendo os mesmos como ingrediente ativo
DK1453810T3 (da) 2001-12-05 2009-07-20 Sanofi Aventis Deutschland Substituerede 4-phenyltetrahydroisoquinoliner, fremgangsmåde til deres fremstilling, deres anvendelse som medikament indeholdende samme
AR038536A1 (es) 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
EP1486490A1 (en) 2002-02-28 2004-12-15 Takeda Chemical Industries, Ltd. Azole compounds
AR040336A1 (es) 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para preparar dicho compuesto
CN1668584A (zh) * 2002-09-20 2005-09-14 鲁宾有限公司 作为抗分支杆菌化合物的吡咯衍生物
US7135469B2 (en) 2003-03-18 2006-11-14 Bristol Myers Squibb, Co. Linear chain substituted monocyclic and bicyclic derivatives as factor Xa inhibitors
DE10316081A1 (de) * 2003-04-08 2004-10-21 Morphochem AG Aktiengesellschaft für kombinatorische Chemie Neue Verbindungen mit antibakterieller Aktivität
JPWO2004089954A1 (ja) 2003-04-08 2006-07-06 大日本住友製薬株式会社 新規なカルバペネム化合物
SE0302116D0 (sv) 2003-07-21 2003-07-21 Astrazeneca Ab Novel compounds
US7094791B2 (en) * 2003-07-31 2006-08-22 Avalon Pharmaceuticals, Inc. Derivatives of 3-hydroxy-pyrrole-2,4-dicarboxylic acid and uses thereof
TW200526626A (en) * 2003-09-13 2005-08-16 Astrazeneca Ab Chemical compounds
GB0325956D0 (en) 2003-11-06 2003-12-10 Addex Pharmaceuticals Sa Novel compounds
US20050197336A1 (en) 2004-03-08 2005-09-08 Miikana Therapeutics Corporation Inhibitors of histone deacetylase
US7345043B2 (en) 2004-04-01 2008-03-18 Miikana Therapeutics Inhibitors of histone deacetylase
EP1790636A4 (en) 2004-09-17 2009-07-01 Takeda Pharmaceutical Piperidin derivatives and their use
JP5008569B2 (ja) 2004-10-22 2012-08-22 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ C−fmsキナーゼのインヒビターとしての芳香族アミド
UA88648C2 (en) 2004-10-22 2009-11-10 Янссэн Фармацэвтика Н.В. Inhibitors of c-fms kinase
EP1853586B1 (en) * 2005-02-18 2013-07-24 AstraZeneca AB Antibacterial piperidine derivatives
US20080161306A1 (en) 2005-02-18 2008-07-03 Brian Sherer Pyrrole Derivatives as Dna Gyrase and Topoisomerase Inhibitors
CN101163697A (zh) 2005-02-18 2008-04-16 阿斯利康(瑞典)有限公司 作为dna促旋酶和拓扑异构酶抑制剂的吡咯衍生物
JP2008531673A (ja) 2005-03-04 2008-08-14 アストラゼネカ アクチボラグ 抗菌活性をもつアゼチジン及びピロールの三環式誘導体
CN101171247A (zh) 2005-03-04 2008-04-30 阿斯利康(瑞典)有限公司 作为dna促旋酶和拓扑异构酶抑制剂的吡咯衍生物
US8071065B2 (en) * 2005-03-31 2011-12-06 Touchstone Research Laboratory, Ltd High density carbon foam composite tooling
US20080312211A1 (en) 2005-12-23 2008-12-18 Astrazeneca Ab Antibacterial Pyrrolopyridines, Pyrrolopyrimidines and Pyrroloazepines-154
TW200819437A (en) 2006-08-17 2008-05-01 Astrazeneca Ab Chemical compounds
TW200906412A (en) * 2007-06-12 2009-02-16 Astrazeneca Ab Piperidine compounds and uses thereof
US8071605B2 (en) * 2008-12-12 2011-12-06 Astrazeneca Ab Piperidine compounds for use in the treatment of bacterial infections

Also Published As

Publication number Publication date
UY29384A1 (es) 2006-10-02
KR20130093174A (ko) 2013-08-21
HK1114376A1 (en) 2008-10-31
JP2007326882A (ja) 2007-12-20
UA94901C2 (ru) 2011-06-25
ZA200706920B (en) 2008-06-25
IL185306A0 (en) 2008-02-09
WO2006087543A8 (en) 2007-10-18
EP1853586A1 (en) 2007-11-14
JP2008500321A (ja) 2008-01-10
US8399489B2 (en) 2013-03-19
TW200640908A (en) 2006-12-01
ES2430569T3 (es) 2013-11-21
TWI402263B (zh) 2013-07-21
CA2598423C (en) 2014-05-27
JP2007326883A (ja) 2007-12-20
BRPI0607756A2 (pt) 2010-05-18
NZ561613A (en) 2010-12-24
AR053683A1 (es) 2007-05-16
US20100179150A1 (en) 2010-07-15
AU2006215399A1 (en) 2006-08-24
IL185306A (en) 2012-05-31
KR20070113233A (ko) 2007-11-28
CN101163693B (zh) 2013-03-06
AU2006215399B2 (en) 2010-12-09
MX2007010072A (es) 2008-01-28
EP1853586B1 (en) 2013-07-24
KR101422432B1 (ko) 2014-07-22
RU2424240C2 (ru) 2011-07-20
WO2006087543A1 (en) 2006-08-24
SA06270020B1 (ar) 2010-10-23
CN101163693A (zh) 2008-04-16
CA2598423A1 (en) 2006-08-24
US20130150366A1 (en) 2013-06-13
RU2007134380A (ru) 2009-03-27
JP2008024715A (ja) 2008-02-07
JP4058106B2 (ja) 2008-03-05

Similar Documents

Publication Publication Date Title
NO20074703L (no) Antibakterielle piperidinderivater
NO20092476L (no) Antibakterielle polycykliske ureaforbindelser
NO20061657L (no) Pyrolderivater med antibakteriell aktivitet
NO20083250L (no) Antibakterielle pyrrolopyridiner, pyrrolopyrimidiner og pyrroloazepiner
NO20062583L (no) Difenylazetidinonderivater med kolesterolabsorpsjonsinhiberende aktivitet
MX2010009163A (es) Derivados heterociclicos de urea y metodos de uso de los mismos-211.
WO2008020227A3 (en) Antibacterial pyrrolecarboxamides
WO2008020229A3 (en) Antibacterial pyrrolecarboxamides
NO20091893L (no) Nye 1,4-benzotiepin-1,1-dioksidderivater som er substituert med benzylgrupper, fremgangsmater for fremstilling av medisiner inneholdende forbindelsene og anvendelse derav.
NO20055421L (no) Kinolinderivater som fosfodiestrase-inhibitorer
NO20083863L (no) Pyrazoler som 11-beta-hsd-1
NO20076197L (no) Nye 2-azetidinonderivater anvendbare i behandling av hyperlipidemiske tilstander
NO20062591L (no) Difenylazetidinonderivater med kolesterolabsorpsjonsinhiberende aktivitet
NO20081844L (no) Terapeutiske forbindelser
NO20076254L (no) Nye 2-azetidinonderivater som kolesterolabsorpsjonsinhibitorer for behandling av hyperlipidemiske tilstander
NO20076137L (no) Nye 2-azetidinonderivater og deres anvendelse som kolestrolabsorpsjonsinhibitorer for behandling av hyperlipidemi
NO20074872L (no) Pyrazoler
NO20082496L (no) Pyrazinderivater
MX2009013501A (es) Compuestos piperidinicos y sus usos.
MX2010013310A (es) Derivados de heterociclil urea para el tratamiento de infecciones bacterianas.
NO20061839L (no) Benzimidazolderivater, sammensetninger inneholdende dem, fremstilling derav, og anvendelse derav
WO2006092599A3 (en) Pyrrole derivatives as dna gyrase and topoisomerase inhibitors
EA201001859A1 (ru) Гетероциклические производные мочевины и способы их применеия
NO20092655L (no) 2-kinolinon- og 2-kinoksalinonderivater og deres anvendelse som antibakterielle midler
TW200639156A (en) New compounds

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application