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NO20072833L - Bi- og tricykliske substituterte fenylmetanoner som glycinetransportor I-(Glyt-1)-inhibitorer for behandling av Alzheimers sykdom - Google Patents

Bi- og tricykliske substituterte fenylmetanoner som glycinetransportor I-(Glyt-1)-inhibitorer for behandling av Alzheimers sykdom

Info

Publication number
NO20072833L
NO20072833L NO20072833A NO20072833A NO20072833L NO 20072833 L NO20072833 L NO 20072833L NO 20072833 A NO20072833 A NO 20072833A NO 20072833 A NO20072833 A NO 20072833A NO 20072833 L NO20072833 L NO 20072833L
Authority
NO
Norway
Prior art keywords
lower alkyl
halogen
substituted
treatment
hydrogen
Prior art date
Application number
NO20072833A
Other languages
English (en)
Norwegian (no)
Inventor
Emmanuel Pinard
Synese Jolidon
Roger David Norcross
Robert Narquizian
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO20072833L publication Critical patent/NO20072833L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO20072833A 2004-12-15 2007-06-04 Bi- og tricykliske substituterte fenylmetanoner som glycinetransportor I-(Glyt-1)-inhibitorer for behandling av Alzheimers sykdom NO20072833L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04106597 2004-12-15
PCT/EP2005/012994 WO2006063709A1 (fr) 2004-12-15 2005-12-05 Utilisation de phenylmethanones substituees bicycliques et tricycliques comme inhibiteurs des transporteurs de la glycine i (glyt-1) pour traiter la maladie d'alzheimer

Publications (1)

Publication Number Publication Date
NO20072833L true NO20072833L (no) 2007-07-17

Family

ID=35841863

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20072833A NO20072833L (no) 2004-12-15 2007-06-04 Bi- og tricykliske substituterte fenylmetanoner som glycinetransportor I-(Glyt-1)-inhibitorer for behandling av Alzheimers sykdom

Country Status (20)

Country Link
US (1) US7375226B2 (fr)
EP (1) EP1828200B1 (fr)
JP (1) JP4709849B2 (fr)
KR (1) KR100883003B1 (fr)
CN (1) CN100586951C (fr)
AR (1) AR052156A1 (fr)
AT (1) ATE457989T1 (fr)
AU (1) AU2005315914B2 (fr)
BR (1) BRPI0519054A2 (fr)
CA (1) CA2590316A1 (fr)
DE (1) DE602005019465D1 (fr)
ES (1) ES2338139T3 (fr)
IL (1) IL183592A0 (fr)
MX (1) MX2007006896A (fr)
NO (1) NO20072833L (fr)
NZ (1) NZ555476A (fr)
RU (1) RU2007121768A (fr)
TW (1) TWI299041B (fr)
WO (1) WO2006063709A1 (fr)
ZA (1) ZA200705044B (fr)

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PT2968320T (pt) 2013-03-15 2021-01-28 Intra Cellular Therapies Inc Compostos orgânicos
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EP3125892A4 (fr) 2014-04-04 2017-12-27 Intra-Cellular Therapies, Inc. Composés organiques
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Also Published As

Publication number Publication date
AU2005315914A1 (en) 2006-06-22
AR052156A1 (es) 2007-03-07
MX2007006896A (es) 2007-06-26
IL183592A0 (en) 2007-09-20
TWI299041B (en) 2008-07-21
AU2005315914B2 (en) 2011-03-03
ZA200705044B (en) 2008-09-25
CN100586951C (zh) 2010-02-03
ATE457989T1 (de) 2010-03-15
NZ555476A (en) 2009-09-25
JP2008523126A (ja) 2008-07-03
JP4709849B2 (ja) 2011-06-29
TW200634017A (en) 2006-10-01
BRPI0519054A2 (pt) 2008-12-23
CN101076532A (zh) 2007-11-21
ES2338139T3 (es) 2010-05-04
WO2006063709A1 (fr) 2006-06-22
US20060128713A1 (en) 2006-06-15
RU2007121768A (ru) 2009-01-27
US7375226B2 (en) 2008-05-20
KR100883003B1 (ko) 2009-02-12
DE602005019465D1 (de) 2010-04-01
CA2590316A1 (fr) 2006-06-22
EP1828200A1 (fr) 2007-09-05
EP1828200B1 (fr) 2010-02-17
KR20070086196A (ko) 2007-08-27

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