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NO20045577L - Oralt desintegrerende tabletter og fremgangsmate for a oppna dem - Google Patents

Oralt desintegrerende tabletter og fremgangsmate for a oppna dem

Info

Publication number
NO20045577L
NO20045577L NO20045577A NO20045577A NO20045577L NO 20045577 L NO20045577 L NO 20045577L NO 20045577 A NO20045577 A NO 20045577A NO 20045577 A NO20045577 A NO 20045577A NO 20045577 L NO20045577 L NO 20045577L
Authority
NO
Norway
Prior art keywords
particle size
obtaining
methods
blending
lubricant
Prior art date
Application number
NO20045577A
Other languages
English (en)
Other versions
NO334159B1 (no
Inventor
Javier Segado Ferran
Original Assignee
Vita Cientifica Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29724735&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20045577(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vita Cientifica Srl filed Critical Vita Cientifica Srl
Publication of NO20045577L publication Critical patent/NO20045577L/no
Publication of NO334159B1 publication Critical patent/NO334159B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Det beskrives tabletter som omfatter minst 59,5 % spraytørket mannitol, aktiv ingrediens under eller lik 10 %, hvori minst 90 vekt% av den aktive ingrediens har en partikkelstørrelse under 100 (m, mikrokrystallinsk cellulose 10-18 %, med en gjennomsnittelig partikkelstørrelse på 50 (m og hvor minst 99 vekt% av den mikrokrystallinske cellulose har en partikkelstørrelse under 250 (m, natriumkroskarmellose 1- 4 %, og et smøremiddel 0,5-2 %, hvor, med mindre noe annet er spesifisert, prosentandelene er uttrykt i vekt regnet på tablettens totale vekt. Det beskrives også en fremgangsmåte som omfatter siling og blanding av komponentene med unntagelse av smøremidlet, blanding av alle komponentene, og direkte kompresjon av den endelige blanding. Tablettene i henhold til oppfinnelsen gir lavere des integrasjonstider så vel som god persepsjon på tungen etter desintegrering, og overvinner problemet med utilstrekkelig mekanisk motstand for pakking og transport.
NO20045577A 2002-06-10 2004-12-21 Oralt desintegrerende tabletter og fremgangsmåte for å oppnå dem NO334159B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200201440A ES2199061B1 (es) 2002-06-10 2002-06-10 Comprimidos bucodispersables y procedimiento para su obtencion.
PCT/IB2003/002446 WO2003103629A1 (en) 2002-06-10 2003-06-04 Orally disintegrating tablets and process for obtaining them.

Publications (2)

Publication Number Publication Date
NO20045577L true NO20045577L (no) 2004-12-21
NO334159B1 NO334159B1 (no) 2013-12-23

Family

ID=29724735

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20045577A NO334159B1 (no) 2002-06-10 2004-12-21 Oralt desintegrerende tabletter og fremgangsmåte for å oppnå dem

Country Status (32)

Country Link
US (1) US20060165781A1 (no)
EP (1) EP1534237B1 (no)
JP (1) JP2005533045A (no)
KR (1) KR100826819B1 (no)
CN (1) CN100428926C (no)
AR (1) AR040183A1 (no)
AT (1) ATE422154T1 (no)
AU (1) AU2003232415B2 (no)
BR (1) BR0311708A (no)
CA (1) CA2487834C (no)
CY (1) CY1108961T1 (no)
DE (1) DE60326074D1 (no)
DK (1) DK1534237T3 (no)
EG (1) EG25919A (no)
ES (2) ES2199061B1 (no)
HR (1) HRP20041158B1 (no)
IL (1) IL165523A (no)
JO (1) JO2560B1 (no)
MA (1) MA27309A1 (no)
MX (1) MXPA04012464A (no)
MY (1) MY139585A (no)
NO (1) NO334159B1 (no)
NZ (1) NZ536966A (no)
PE (1) PE20040069A1 (no)
PL (1) PL207009B1 (no)
PT (1) PT1534237E (no)
RU (1) RU2321389C2 (no)
SA (1) SA03240275B1 (no)
SI (1) SI1534237T1 (no)
TW (1) TWI288002B (no)
WO (1) WO2003103629A1 (no)
ZA (1) ZA200409894B (no)

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Also Published As

Publication number Publication date
DK1534237T3 (da) 2009-05-04
MY139585A (en) 2009-10-30
AU2003232415B2 (en) 2008-05-15
IL165523A0 (en) 2006-01-15
AU2003232415A1 (en) 2003-12-22
CA2487834A1 (en) 2003-12-18
AR040183A1 (es) 2005-03-16
PE20040069A1 (es) 2004-03-25
ES2199061A1 (es) 2004-02-01
SA03240275B1 (ar) 2008-11-19
EP1534237B1 (en) 2009-02-04
ATE422154T1 (de) 2009-02-15
SI1534237T1 (sl) 2009-06-30
RU2004135377A (ru) 2005-09-10
KR20050062467A (ko) 2005-06-23
PL207009B1 (pl) 2010-10-29
ZA200409894B (en) 2006-05-31
MXPA04012464A (es) 2005-06-08
WO2003103629A1 (en) 2003-12-18
ES2320753T3 (es) 2009-05-28
RU2321389C2 (ru) 2008-04-10
CY1108961T1 (el) 2014-07-02
ES2199061B1 (es) 2005-02-16
EP1534237A1 (en) 2005-06-01
HK1076252A1 (zh) 2006-01-13
EG25919A (en) 2012-10-15
TW200403080A (en) 2004-03-01
HRP20041158A2 (en) 2005-04-30
IL165523A (en) 2011-07-31
MA27309A1 (fr) 2005-05-02
JP2005533045A (ja) 2005-11-04
BR0311708A (pt) 2005-03-15
CN100428926C (zh) 2008-10-29
CA2487834C (en) 2009-07-14
KR100826819B1 (ko) 2008-05-02
NZ536966A (en) 2006-08-31
TWI288002B (en) 2007-10-11
DE60326074D1 (de) 2009-03-19
US20060165781A1 (en) 2006-07-27
PL374197A1 (en) 2005-10-03
PT1534237E (pt) 2009-05-05
NO334159B1 (no) 2013-12-23
CN1658838A (zh) 2005-08-24
HRP20041158B1 (en) 2012-11-30
JO2560B1 (en) 2010-09-05

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