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NO20001288L - Substituerte 1,2,3,4,5,6-heksahydro-2,6-metano-3-benzazocin- 10-oler, fremgangsmõte for fremstilling derav og anvendelse som legemiddel - Google Patents

Substituerte 1,2,3,4,5,6-heksahydro-2,6-metano-3-benzazocin- 10-oler, fremgangsmõte for fremstilling derav og anvendelse som legemiddel

Info

Publication number
NO20001288L
NO20001288L NO20001288A NO20001288A NO20001288L NO 20001288 L NO20001288 L NO 20001288L NO 20001288 A NO20001288 A NO 20001288A NO 20001288 A NO20001288 A NO 20001288A NO 20001288 L NO20001288 L NO 20001288L
Authority
NO
Norway
Prior art keywords
benzazocin
methano
hexahydro
medicaments
oils
Prior art date
Application number
NO20001288A
Other languages
English (en)
Other versions
NO20001288D0 (no
NO315650B1 (no
Inventor
Matthias Grauert
Adrian Carter
Wolf-Dietrich Bechtel
Thomas Weiser
Rainer Palluk
Uwe Pschorn
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of NO20001288D0 publication Critical patent/NO20001288D0/no
Publication of NO20001288L publication Critical patent/NO20001288L/no
Publication of NO315650B1 publication Critical patent/NO315650B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO20001288A 1997-09-12 2000-03-10 Substituerte 1,2,3,4,5,6-heksahydro-2,6-metano-3-benzazocin- 10-oler, anvendelse derav og fremgangsmåte for deres fremstilling samtfarmasöytisk preparat NO315650B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19740110A DE19740110A1 (de) 1997-09-12 1997-09-12 Substituierte 1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocin-10-ole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
PCT/EP1998/005734 WO1999014199A1 (de) 1997-09-12 1998-09-09 Substituierte 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-10-ole, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (3)

Publication Number Publication Date
NO20001288D0 NO20001288D0 (no) 2000-03-10
NO20001288L true NO20001288L (no) 2000-03-13
NO315650B1 NO315650B1 (no) 2003-10-06

Family

ID=7842134

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20001288A NO315650B1 (no) 1997-09-12 2000-03-10 Substituerte 1,2,3,4,5,6-heksahydro-2,6-metano-3-benzazocin- 10-oler, anvendelse derav og fremgangsmåte for deres fremstilling samtfarmasöytisk preparat

Country Status (38)

Country Link
US (1) US6455538B1 (no)
EP (1) EP1015433B1 (no)
JP (1) JP3827528B2 (no)
KR (1) KR100601008B1 (no)
CN (1) CN1166640C (no)
AR (1) AR017095A1 (no)
AT (1) ATE267811T1 (no)
AU (1) AU751036B2 (no)
BG (1) BG64418B1 (no)
BR (1) BR9812443A (no)
CA (1) CA2302347C (no)
CO (1) CO5011117A1 (no)
CZ (1) CZ296909B6 (no)
DE (2) DE19740110A1 (no)
DK (1) DK1015433T3 (no)
EE (1) EE04398B1 (no)
ES (1) ES2222612T3 (no)
HR (1) HRP980502B1 (no)
HU (1) HUP0004588A3 (no)
ID (1) ID24173A (no)
IL (1) IL134572A (no)
MY (1) MY120550A (no)
NO (1) NO315650B1 (no)
NZ (1) NZ503710A (no)
PE (1) PE122899A1 (no)
PL (1) PL198486B1 (no)
PT (1) PT1015433E (no)
RS (1) RS49888B (no)
RU (1) RU2218334C2 (no)
SA (1) SA98190765B1 (no)
SK (1) SK284670B6 (no)
TR (1) TR200000697T2 (no)
TW (1) TW505645B (no)
UA (1) UA61973C2 (no)
UY (2) UY25175A1 (no)
WO (1) WO1999014199A1 (no)
YU (1) YU12000A (no)
ZA (1) ZA988285B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19826365A1 (de) * 1998-06-12 1999-12-16 Gruenenthal Gmbh Verwendung von Benzomorphanderivaten als Analgetikum
US6355652B1 (en) 1999-11-27 2002-03-12 Boehringer Ingelheim Pharma Kg Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocines and their use as pharmaceutical compositions
DE19957156A1 (de) * 1999-11-27 2001-05-31 Boehringer Ingelheim Pharma Substituierte 1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocine und ihre Verwendung als Arzneimittel
DE10204276A1 (de) * 2002-02-02 2003-08-07 Boehringer Ingelheim Pharma N-Allyloxyethyl-1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocine und ihre Verwendung als Arzneimittel
US6683089B2 (en) 2002-02-02 2004-01-27 Boehringer Ingelheim Pharma Gmbh & Co. Kg N-allyoxyethyl-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocine-10-ols
US6828311B2 (en) 2002-05-29 2004-12-07 Boehringer Ingelheim Pharma Gmbh & Co. Kg Formulation for the parenteral application of a sodium channel blocker
US20040019075A1 (en) * 2002-05-29 2004-01-29 Boehringer Ingelheim Pharma Gmbh & Co. Kg New formulation for the parenteral application of crobenetine
DE10223783A1 (de) * 2002-05-29 2003-12-11 Boehringer Ingelheim Pharma Neue Formulierung zur parenteralen Applikation eines Na-Kanal-Blockers
US20030235576A1 (en) * 2002-06-15 2003-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg New drug combinations for the treatment of ischaemic conditions
DE10226814A1 (de) * 2002-06-15 2004-01-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkombinationen zur Behandlung ischämischer Zustände
SI1963280T1 (sl) 2005-12-22 2016-02-29 Newron Pharmaceuticals S.P.A. 2-feniletilamino derivati kot modulatorji kalcijevih in/ali natrijevih kanalčkov
WO2008151702A1 (en) 2007-06-15 2008-12-18 Newron Pharmaceuticals S.P.A. Substituted 2- [2- (phenyl) ethylamino] alkaneamide derivatives and their use as sodium and/or calcium channel modulators
HRP20161412T1 (hr) 2011-06-27 2016-12-02 Newron Pharmaceuticals S.P.A. Fluorirani derivati arilalkilaminokarboksamida

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
US4208523A (en) * 1978-11-30 1980-06-17 Sterling Drug Inc. 11-Lower-alkyl-, 11-phenyl-lower-alkyl- and 11-cyclo-lower-alkyl-lower-alkyl-hexahydro-2,6-methano-3-benzazocines
DE4121821A1 (de) 1991-07-02 1993-01-14 Boehringer Ingelheim Kg Neue benzomorphane und ihre verwendung als arzneimittel
US5607941A (en) * 1992-06-26 1997-03-04 Boehringer Ingelheim Kg Useful for treating neurodegenerative diseases
DE19528472A1 (de) * 1995-08-03 1997-02-06 Boehringer Ingelheim Kg Neues Verfahren zur Herstellung von Norbenzomorphan einer Zwischenstufe bei Herstellung von pharmazeutisch wertvollen Benzomorphanderivaten, insbesondere von (-)-(1R,5S,S"R)-3'-Hydroxy-2-(2-methoxypropyl-)-5,9,9-trimethyl-6,7 benzomorphan

Also Published As

Publication number Publication date
HUP0004588A2 (hu) 2001-07-30
UA61973C2 (en) 2003-12-15
AU9624298A (en) 1999-04-05
PL339061A1 (en) 2000-12-04
BG104232A (bg) 2000-10-31
CZ2000894A3 (cs) 2000-09-13
MY120550A (en) 2005-11-30
AR017095A1 (es) 2001-08-22
CA2302347C (en) 2008-06-17
YU12000A (sh) 2002-11-15
HUP0004588A3 (en) 2002-10-28
CZ296909B6 (cs) 2006-07-12
TW505645B (en) 2002-10-11
HRP980502B1 (en) 2005-02-28
NO20001288D0 (no) 2000-03-10
EP1015433B1 (de) 2004-05-26
UY25175A1 (es) 2000-12-29
BR9812443A (pt) 2000-09-26
TR200000697T2 (tr) 2001-01-22
UY25439A1 (es) 1999-11-17
EE200000129A (et) 2001-02-15
BG64418B1 (bg) 2005-01-31
CN1166640C (zh) 2004-09-15
SK3342000A3 (en) 2000-09-12
DE19740110A1 (de) 1999-03-18
CO5011117A1 (es) 2001-02-28
WO1999014199A1 (de) 1999-03-25
KR20010023879A (ko) 2001-03-26
PT1015433E (pt) 2004-08-31
EE04398B1 (et) 2004-12-15
JP2001516747A (ja) 2001-10-02
RU2218334C2 (ru) 2003-12-10
SK284670B6 (sk) 2005-08-04
PL198486B1 (pl) 2008-06-30
JP3827528B2 (ja) 2006-09-27
NO315650B1 (no) 2003-10-06
NZ503710A (en) 2002-04-26
IL134572A (en) 2005-05-17
DE59811477D1 (de) 2004-07-01
ES2222612T3 (es) 2005-02-01
RS49888B (sr) 2008-08-07
HRP980502A2 (en) 1999-06-30
IL134572A0 (en) 2001-04-30
DK1015433T3 (da) 2004-09-27
CA2302347A1 (en) 1999-03-25
EP1015433A1 (de) 2000-07-05
PE122899A1 (es) 1999-12-06
CN1269790A (zh) 2000-10-11
SA98190765B1 (ar) 2006-06-10
KR100601008B1 (ko) 2006-07-19
ZA988285B (en) 1999-03-12
ATE267811T1 (de) 2004-06-15
US6455538B1 (en) 2002-09-24
ID24173A (id) 2000-07-13
AU751036B2 (en) 2002-08-08

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