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NI201300101A - Modulación de la expresión del transductor de señales y activador de la transcripción 3 (stat3) - Google Patents

Modulación de la expresión del transductor de señales y activador de la transcripción 3 (stat3)

Info

Publication number
NI201300101A
NI201300101A NI201300101A NI201300101A NI201300101A NI 201300101 A NI201300101 A NI 201300101A NI 201300101 A NI201300101 A NI 201300101A NI 201300101 A NI201300101 A NI 201300101A NI 201300101 A NI201300101 A NI 201300101A
Authority
NI
Nicaragua
Prior art keywords
expression
stat3
modulation
signal transducer
transcription activator
Prior art date
Application number
NI201300101A
Other languages
English (en)
Inventor
E Swayze Eric
M Freier Susan
A Macleod Robert
Kim Youngsoo
Original Assignee
Isis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isis Pharmaceuticals Inc filed Critical Isis Pharmaceuticals Inc
Publication of NI201300101A publication Critical patent/NI201300101A/es

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    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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Abstract

Se describen en la presente compuestos antisentido y métodos para disminuir la expresión de ARNm y proteínas STAT3. Dichos métodos, compuestos y composiciones son de utilidad para tratar, prevenir o aliviar enfermedades hiperproliferativas.
NI201300101A 2011-04-01 2013-09-30 Modulación de la expresión del transductor de señales y activador de la transcripción 3 (stat3) NI201300101A (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201161471015P 2011-04-01 2011-04-01
US201161471001P 2011-04-01 2011-04-01
US201161471035P 2011-04-01 2011-04-01
US201161471045P 2011-04-01 2011-04-01
US201161558308P 2011-11-10 2011-11-10
US201161558316P 2011-11-10 2011-11-10

Publications (1)

Publication Number Publication Date
NI201300101A true NI201300101A (es) 2014-07-08

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NI201300101A NI201300101A (es) 2011-04-01 2013-09-30 Modulación de la expresión del transductor de señales y activador de la transcripción 3 (stat3)

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US (4) US8816056B2 (es)
EP (2) EP2697243B1 (es)
JP (1) JP5943993B2 (es)
KR (2) KR20190092590A (es)
CN (2) CN103562215B (es)
AU (1) AU2012236206C1 (es)
BR (1) BR112013024768B1 (es)
CA (1) CA2831915C (es)
CL (1) CL2013002773A1 (es)
CO (1) CO6821885A2 (es)
CY (1) CY1121460T1 (es)
DK (1) DK2697243T3 (es)
DO (1) DOP2013000216A (es)
EA (2) EA029317B1 (es)
EC (1) ECSP13012909A (es)
ES (1) ES2709495T3 (es)
GT (1) GT201300232A (es)
HR (1) HRP20182169T1 (es)
HU (1) HUE042173T2 (es)
IL (2) IL228569A (es)
LT (1) LT2697243T (es)
ME (1) ME03317B (es)
MX (1) MX340086B (es)
MY (1) MY163004A (es)
NI (1) NI201300101A (es)
PE (2) PE20142463A1 (es)
PH (1) PH12013502049A1 (es)
PL (1) PL2697243T3 (es)
PT (1) PT2697243T (es)
RS (1) RS58489B1 (es)
SG (1) SG193504A1 (es)
SI (1) SI2697243T1 (es)
SM (1) SMT201900060T1 (es)
WO (1) WO2012135736A2 (es)
ZA (1) ZA201308153B (es)

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