MY8700793A - 9-(1,3-dihydroxy-2-propoxymethyl)-guanine as anti viral agent - Google Patents

9-(1,3-dihydroxy-2-propoxymethyl)-guanine as anti viral agent

Info

Publication number: MY8700793A
Authority: MY; Malaysia
Prior art keywords: propoxymethyl; guanine; dihydroxy; viral agent; anti viral
Prior art date: 1981-05-21

Application number

MY793/87A

Other languages

English (en)

Inventor

Julian P Verheyden

John C Martin

Original Assignee

Syntex Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-05-21

Filing date

1987-12-30

Publication date

1987-12-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23017790&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MY8700793(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1987-12-30 Application filed by Syntex Inc filed Critical Syntex Inc

1987-12-31 Publication of MY8700793A publication Critical patent/MY8700793A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Virology (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

MY793/87A 1981-05-21 1987-12-30 9-(1,3-dihydroxy-2-propoxymethyl)-guanine as anti viral agent MY8700793A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06267210 US4355032B2 (en)	1981-05-21	1981-05-21	9-(1,3-dihydroxy-2-propoxymethyl)guanine as antiviral agent

Publications (1)

Publication Number	Publication Date
MY8700793A true MY8700793A (en)	1987-12-31

Family

ID=23017790

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MY793/87A MY8700793A (en)	1981-05-21	1987-12-30	9-(1,3-dihydroxy-2-propoxymethyl)-guanine as anti viral agent

Country Status (33)

Country	Link
US (1)	US4355032B2 (fr)
EP (1)	EP0066208B1 (fr)
JP (2)	JPS57203086A (fr)
KR (1)	KR890004663B1 (fr)
AR (1)	AR244227A1 (fr)
AT (1)	ATE15899T1 (fr)
AU (1)	AU572086B2 (fr)
BR (1)	BR8202931A (fr)
CA (3)	CA1305141C (fr)
CS (4)	CS235042B2 (fr)
DD (2)	DD203052A5 (fr)
DE (1)	DE3266644D1 (fr)
DK (2)	DK150304C (fr)
ES (7)	ES512414A0 (fr)
FI (1)	FI73682C (fr)
GR (1)	GR76459B (fr)
HK (1)	HK67088A (fr)
HU (2)	HU188000B (fr)
IE (1)	IE53731B1 (fr)
IL (1)	IL65836A (fr)
IN (1)	IN156469B (fr)
LU (1)	LU88334I2 (fr)
MY (1)	MY8700793A (fr)
NL (2)	NL930022I1 (fr)
NO (2)	NO161740C (fr)
NZ (1)	NZ200691A (fr)
PH (1)	PH17975A (fr)
PL (4)	PL136637B1 (fr)
PT (1)	PT74934B (fr)
RO (2)	RO87387B (fr)
SG (1)	SG81687G (fr)
SU (1)	SU1176841A3 (fr)
ZA (1)	ZA823532B (fr)

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US4347360A (en) *	1980-09-16	1982-08-31	Ens Bio Logicals Inc.	Ring open nucleoside analogues
US5157120A (en) *	1980-09-16	1992-10-20	Syntex (U.S.A.) Inc.	Guanine derivatives
US4507305A (en) *	1981-05-21	1985-03-26	Syntex (U.S.A.) Inc.	9-(1,3-Dihydroxy-2-propoxymethyl)guanine as antiviral agent
US4423050A (en) *	1981-05-21	1983-12-27	Syntex (U.S.A.) Inc.	9-(1,3-Dihydroxy-2-propoxymethyl)guanine as antiviral agent
IE54148B1 (en) *	1981-08-11	1989-07-05	Wellcome Found	Antiviral compounds
NZ201662A (en) *	1981-08-26	1986-07-11	Merck & Co Inc	9-(1,3-(and 2,3)-dihydroxy-1-(and 2)-propoxy-methyl)guanine derivatives and methods for their preparation
IE830186L (en) *	1982-02-01	1983-08-01	Syntex Inc	Purines
US5250535A (en) *	1982-02-01	1993-10-05	Syntex Inc.	Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent
US4902678A (en) *	1982-02-12	1990-02-20	Syntex (U.S.A.) Inc.	Anti-viral compositions
US4609662A (en) *	1982-10-14	1986-09-02	Burroughs Wellcome Co.	Method for using purine derivatives
US4462986A (en) *	1982-11-04	1984-07-31	Ens Bio Logicals, Inc.	Synergistic anti-herpes compositions
US4814335A (en) *	1982-12-30	1989-03-21	Biomeasure, Incorporated	Antiviral compounds
US4461757A (en) *	1983-02-23	1984-07-24	Ens Bio Logicals Inc.	Dimethylaminomethylenated anti-herpes compounds
US5047533A (en) *	1983-05-24	1991-09-10	Sri International	Acyclic purine phosphonate nucleotide analogs
US4880820A (en) *	1983-06-24	1989-11-14	Merck & Co., Inc.	Guanine derivatives
GB8320308D0 (en) *	1983-07-28	1983-09-01	Wellcome Found	Antiviral combinations
US4897479A (en) *	1983-09-30	1990-01-30	Merck & Co., Inc.	Arylsulfonyloxy purine intermediates
EP0138683A3 (fr) *	1983-09-30	1988-01-20	Merck & Co. Inc.	Dérivés de purine, leur application dans des compositions anti-virales
IE842642L (en) *	1983-10-31	1985-04-30	Harvard College	Purine Derivatives
US4806642A (en) *	1984-10-05	1989-02-21	Warner-Lambert Company	Purine derivatives
IL73682A (en) *	1983-12-20	1991-08-16	Medivir Ab	Antiviral pharmaceutical compositions containing 9-hydroxy aliphatic derivatives of guanine,some new such derivatives and process for their preparation
US4621140A (en) *	1984-02-23	1986-11-04	Syntex (U.S.A.) Inc.	Process for preparing 2,6-substituted-9-(1,3-dihydroxy-2-propoxymethyl)-purines and certain derivatives
US4579849A (en) *	1984-04-06	1986-04-01	Merck & Co., Inc.	N-alkylguanine acyclonucleosides as antiviral agents
WO1986000901A1 (fr) *	1984-07-20	1986-02-13	Gauntt Charles O	Compose immunoregulateur et anti-viral
NO172183C (no) *	1984-12-12	1993-06-16	Syntex Inc	Fremgangsmaate for fremstilling av derivater av 9-(1,3-dikydroksy-2-propoksymetyl)-guanin
SE8406538D0 (sv)	1984-12-21	1984-12-21	Astra Laekemedel Ab	Novel derivatives of purine
US4642346A (en) *	1985-06-24	1987-02-10	Syntex (U.S.A.) Inc.	Anhydrous crystalline 9-(1,3-dihydroxy-2-propoxymethyl)guanine
US4863927A (en) *	1987-05-11	1989-09-05	Merck & Co., Inc.	1-(2-hydroxymethyl)cycloalkylmethyl)-5-substituted uracils
CA2005815C (fr) *	1988-12-19	1999-08-03	Wellcome Foundation Limited (The)	Derives antiviraux de nucleoside acyclique
US5068119A (en) *	1990-09-28	1991-11-26	Nabisco Brands, Inc.	Acid-hydrolyzable ester derivatives as low calorie fat mimetics
GB2260319B (en)	1991-10-07	1995-12-06	Norsk Hydro As	Acyl derivatives of nucleosides and nucleoside analogues having anti-viral activity
CN1040759C (zh) *	1993-06-23	1998-11-18	默里尔药物公司	作为抗病毒剂和抗肿瘤剂的碳－无环核苷衍生物
US5543414A (en) *	1994-07-28	1996-08-06	Syntex (Usa) Inc.	Achiral amino acid acyl esters of ganciclovir and its derivatives
US6083953A (en) *	1994-07-28	2000-07-04	Syntex (U.S.A.) Inc.	2- (2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3- propanediol derivative
US5565565A (en) *	1994-08-04	1996-10-15	Syntex (U.S.A.) Inc.	Preparation of N-9 substituted guanine compounds
US5627185A (en) *	1994-11-23	1997-05-06	Gosselin; Gilles	Acyclovir derivatives as antiviral agents
US5840763A (en) *	1994-12-12	1998-11-24	Smithkline Beecham Plc	Treatment of a latent infection of herpes viruses
DE19536164A1 (de) *	1995-09-28	1997-04-03	Boehringer Ingelheim Kg	Verbessertes Verfahren zur Herstellung von 9-[(2-Hyroxyethoxy)methyl]guanin (Acyclovir)
US5700936A (en) *	1996-01-26	1997-12-23	Syntex (U.S.A.) Inc.	Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol valinate
US5756736A (en) *	1996-01-26	1998-05-26	Syntex (U.S.A.) Inc.	Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
US5840890A (en) *	1996-01-26	1998-11-24	Syntex (U.S.A.) Inc.	Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
US6040446A (en)	1996-01-26	2000-03-21	Syntex (U.S.A.) Inc.	Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative
IN179493B (fr) *	1996-02-22	1997-10-11	Lupin Laboraties Ltd
EP0806425B1 (fr) *	1996-04-09	2001-08-29	Lupin Laboratories Limited	Procédé régiospécifique amélioré pour la synthèse de nucléosides acycliques
US5852208A (en) *	1996-08-30	1998-12-22	Dixie Chemical Company, Inc.	Method of producing compounds containing acyloxyalkoxy groups from alcohols
CN1091445C (zh) *	1999-12-29	2002-09-25	湖北省医药工业研究院	抗病毒药物中间体、它们的制备及应用
CA2477088A1 (fr)	2002-02-22	2003-10-02	New River Pharmaceuticals Inc.	Systemes de distribution d'agents actifs et methodes de protection et d'administration d'agents actifs
WO2004037263A1 (fr) *	2002-10-22	2004-05-06	Ranbaxy Laboratories Limited	Compositions pharmaceutiques de ganciclovir
US20060142574A1 (en) *	2002-10-31	2006-06-29	Babu Jayachandra S	Process for the preparation of ganciclovir
WO2004048380A1 (fr) *	2002-11-22	2004-06-10	Ranbaxy Laboratories Limited	Procede de synthese de ganciclovir
JP4996241B2 (ja)	2003-01-14	2012-08-08	ギリアードサイエンシーズ，インコーポレイテッド	組み合わせ抗ウイルス治療のための組成物および方法
ITMI20031202A1 (it) *	2003-06-13	2004-12-14	Lyogen Ltd	Forma di cristallina del ganciclovir
WO2005021549A1 (fr) *	2003-08-28	2005-03-10	Ranbaxy Laboratories Limited	Chlorhydrate de valganciclovir amorphe
JP4746866B2 (ja) *	2004-11-19	2011-08-10	Ｔｃｍ株式会社	キャリッジ用ガタ抑制装置
TWI375560B (en) *	2005-06-13	2012-11-01	Gilead Sciences Inc	Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same
TWI471145B (zh)	2005-06-13	2015-02-01	Bristol Myers Squibb & Gilead Sciences Llc	單一式藥學劑量型
EP2085397A1 (fr)	2008-01-21	2009-08-05	Esteve Quimica, S.A.	Forme cristalline d'abacavir
WO2009120358A1 (fr) *	2008-03-27	2009-10-01	Nektar Therapeutics	Conjugués oligomère-base azotée
US8173621B2 (en)	2008-06-11	2012-05-08	Gilead Pharmasset Llc	Nucleoside cyclicphosphates
US8716263B2 (en)	2008-12-23	2014-05-06	Gilead Pharmasset Llc	Synthesis of purine nucleosides
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US8551973B2 (en) *	2008-12-23	2013-10-08	Gilead Pharmasset Llc	Nucleoside analogs
CN101851239B (zh) *	2009-04-03	2012-11-28	上海益威实业有限公司	一种更昔洛韦的回收方法
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CA2889903C (fr)	2012-10-29	2021-03-09	Manjinder Singh Phull	Analogues de phosphonate antiviraux et leur procede de preparation
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Family Cites Families (7)

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GB1523865A (en) *	1974-09-02	1978-09-06	Wellcome Found	Purine compunds and salts thereof
US4199574A (en) *	1974-09-02	1980-04-22	Burroughs Wellcome Co.	Methods and compositions for treating viral infections and guanine acyclic nucleosides
US4060616A (en) *	1976-03-01	1977-11-29	Burroughs Wellcome Co.	Purine derivatives with repeating unit
US4221910A (en) *	1978-09-15	1980-09-09	Newport Pharmaceuticals International, Inc.	9-(Hydroxy alkyl)purines
US4347360A (en) *	1980-09-16	1982-08-31	Ens Bio Logicals Inc.	Ring open nucleoside analogues
AU7938482A (en) *	1980-12-22	1982-07-20	Astra Lakemedel Aktiebolag	Novel derivatives of guanine
IE54148B1 (en) *	1981-08-11	1989-07-05	Wellcome Found	Antiviral compounds

1981
- 1981-05-21 US US06267210 patent/US4355032B2/en not_active Expired - Lifetime
1982
- 1982-05-19 DE DE8282104433T patent/DE3266644D1/de not_active Expired
- 1982-05-19 AT AT82104433T patent/ATE15899T1/de active
- 1982-05-19 DK DK227782A patent/DK150304C/da not_active IP Right Cessation
- 1982-05-19 EP EP82104433A patent/EP0066208B1/fr not_active Expired
- 1982-05-19 NO NO821676A patent/NO161740C/no not_active IP Right Cessation
- 1982-05-20 PL PL1982242100A patent/PL136637B1/pl unknown
- 1982-05-20 SU SU823443852A patent/SU1176841A3/ru active
- 1982-05-20 FI FI821794A patent/FI73682C/fi not_active IP Right Cessation
- 1982-05-20 HU HU844011A patent/HU188000B/hu unknown
- 1982-05-20 CA CA000604470A patent/CA1305141C/fr not_active Expired - Lifetime
- 1982-05-20 PT PT74934A patent/PT74934B/pt unknown
- 1982-05-20 AU AU83892/82A patent/AU572086B2/en not_active Expired
- 1982-05-20 GR GR68199A patent/GR76459B/el unknown
- 1982-05-20 IE IE1210/82A patent/IE53731B1/en active Protection Beyond IP Right Term
- 1982-05-20 JP JP57085655A patent/JPS57203086A/ja active Granted
- 1982-05-20 CS CS834402A patent/CS235042B2/cs unknown
- 1982-05-20 CS CS834404A patent/CS235044B2/cs unknown
- 1982-05-20 AR AR82289466A patent/AR244227A1/es active
- 1982-05-20 PL PL1982236521A patent/PL136332B1/pl unknown
- 1982-05-20 PL PL1982246770A patent/PL136579B1/pl unknown
- 1982-05-20 CS CS823735A patent/CS235018B2/cs unknown
- 1982-05-20 RO RO112367A patent/RO87387B/ro unknown
- 1982-05-20 PL PL1982242101A patent/PL136004B1/pl unknown
- 1982-05-20 CS CS834403A patent/CS235043B2/cs unknown
- 1982-05-20 ES ES512414A patent/ES512414A0/es active Granted
- 1982-05-20 IN IN564/CAL/82A patent/IN156469B/en unknown
- 1982-05-20 PH PH27320A patent/PH17975A/en unknown
- 1982-05-20 BR BR8202931A patent/BR8202931A/pt unknown
- 1982-05-20 CA CA000495721A patent/CA1305140C/fr not_active Expired - Lifetime
- 1982-05-20 RO RO107610A patent/RO84860B/ro unknown
- 1982-05-20 NZ NZ200691A patent/NZ200691A/en unknown
- 1982-05-20 KR KR8202204A patent/KR890004663B1/ko not_active Expired
- 1982-05-20 HU HU821614A patent/HU186514B/hu unknown
- 1982-05-20 CA CA000403368A patent/CA1305139C/fr not_active Expired - Lifetime
- 1982-05-20 IL IL65836A patent/IL65836A/xx not_active IP Right Cessation
- 1982-05-21 DD DD82240075A patent/DD203052A5/de not_active IP Right Cessation
- 1982-05-21 ZA ZA823532A patent/ZA823532B/xx unknown
- 1982-05-21 DD DD82256251A patent/DD213218A5/de not_active IP Right Cessation
1983
- 1983-03-22 ES ES520849A patent/ES520849A0/es active Granted
- 1983-08-12 ES ES524900A patent/ES8601204A1/es not_active Expired
- 1983-08-12 ES ES524899A patent/ES8507549A1/es not_active Expired
- 1983-11-03 DK DK504183A patent/DK149001C/da not_active IP Right Cessation
1984
- 1984-02-01 ES ES529384A patent/ES8701496A1/es not_active Expired
- 1984-02-01 ES ES529383A patent/ES8606869A1/es not_active Expired
- 1984-06-28 ES ES533821A patent/ES8505681A1/es not_active Expired
1987
- 1987-10-09 SG SG816/87A patent/SG81687G/en unknown
- 1987-12-30 MY MY793/87A patent/MY8700793A/xx unknown
1988
- 1988-08-25 HK HK670/88A patent/HK67088A/en not_active IP Right Cessation
1991
- 1991-04-16 JP JP3084045A patent/JPH04217983A/ja active Granted
1993
- 1993-03-23 NL NL9300022C patent/NL930022I1/nl unknown
- 1993-06-24 LU LU88334C patent/LU88334I2/fr unknown
- 1993-07-01 NL NL930139C patent/NL930139I2/nl unknown
1994
- 1994-07-29 NO NO1994005C patent/NO1994005I1/no unknown

Also Published As

Publication number	Publication date
DD213218A5 (de)	1984-09-05
GR76459B (fr)	1984-08-10
US4355032B2 (en)	1990-10-30
DK227782A (da)	1982-11-22
SU1176841A3 (ru)	1985-08-30
DD203052A5 (de)	1983-10-12
IE53731B1 (en)	1989-02-01
FI73682B (fi)	1987-07-31
ES8500276A1 (es)	1984-11-01
ES524899A0 (es)	1985-09-16
ZA823532B (en)	1983-03-30
RO84860B (ro)	1984-10-30
DK150304C (da)	1988-01-04
DK149001C (da)	1988-11-28
NZ200691A (en)	1986-11-12
PL136579B1 (en)	1986-02-28
LU88334I2 (fr)	1994-09-09
CS235043B2 (en)	1985-04-16
DK150304B (da)	1987-02-02
EP0066208B1 (fr)	1985-10-02
FI73682C (fi)	1987-11-09
DK504183A (da)	1983-11-03
NO161740C (no)	1989-09-20
IL65836A (en)	1991-04-15
PL136332B1 (en)	1986-02-28
SG81687G (en)	1989-07-07
US4355032A (en)	1982-10-19
ES529384A0 (es)	1987-01-01
PL136004B1 (en)	1986-01-31
PT74934A (en)	1982-06-01
IN156469B (fr)	1985-08-10
RO87387A (fr)	1985-08-31
KR890004663B1 (ko)	1989-11-24
NO161740B (no)	1989-06-12
NL930139I1 (nl)	1993-11-01
ES533821A0 (es)	1985-06-16
US4355032B1 (fr)	1983-06-14
JPH0529399B2 (fr)	1993-04-30
PL246770A1 (en)	1984-08-27
JPH046195B2 (fr)	1992-02-05
ES520849A0 (es)	1984-11-01
ES524900A0 (es)	1985-11-16
CS235044B2 (en)	1985-04-16
ES8507549A1 (es)	1985-09-16
HK67088A (en)	1988-09-02
PL236521A1 (en)	1984-01-02
ES8701496A1 (es)	1987-01-01
BR8202931A (pt)	1983-05-03
CA1305141C (fr)	1992-07-14
CA1305140C (fr)	1992-07-14
RO87387B (ro)	1985-08-31
CA1305139C (fr)	1992-07-14
JPH04217983A (ja)	1992-08-07
FI821794A0 (fi)	1982-05-20
IE821210L (en)	1982-11-21
NO1994005I1 (no)	1994-07-29
PT74934B (en)	1984-05-08
JPS57203086A (en)	1982-12-13
ATE15899T1 (de)	1985-10-15
ES8601204A1 (es)	1985-11-16
ES8404355A1 (es)	1984-05-01
AU8389282A (en)	1982-11-25
KR830010112A (ko)	1983-12-26
CS235042B2 (en)	1985-04-16
ES8505681A1 (es)	1985-06-16
DK504183D0 (da)	1983-11-03
NL930139I2 (nl)	1997-07-01
CS235018B2 (en)	1985-04-16
HU186514B (en)	1985-08-28
PL242100A1 (en)	1984-04-24
PL242101A1 (en)	1984-07-16
NL930022I1 (nl)	1993-05-03
ES512414A0 (es)	1984-05-01
IL65836A0 (en)	1982-08-31
RO84860A (fr)	1984-09-29
AU572086B2 (en)	1988-05-05
HU188000B (en)	1986-03-28
AR244227A1 (es)	1993-10-29
NO821676L (no)	1982-11-22
DE3266644D1 (en)	1985-11-07
ES529383A0 (es)	1986-05-16
EP0066208A1 (fr)	1982-12-08
DK149001B (da)	1985-12-16
ES8606869A1 (es)	1986-05-16
PL136637B1 (en)	1986-03-31
PH17975A (en)	1985-02-22

Publication	Publication Date	Title
MY8700793A (en)	1987-12-31	9-(1,3-dihydroxy-2-propoxymethyl)-guanine as anti viral agent
AU1261488A (en)	1988-06-02	Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent
JPS57194106A (en)	1982-11-29	Tire
IL66676A (en)	1985-04-30	Tire
GR77865B (fr)	1984-09-25
JPS57201705A (en)	1982-12-10	Tire
FR2532856B1 (fr)	1985-01-18
DE3272079D1 (en)	1986-08-28	Tripod-type undercarriage
GB8324194D0 (en)	1983-10-12	Caster
FR2525378B1 (fr)	1984-05-25
FR2523576B1 (fr)	1984-05-04
IL61535A0 (en)	1980-12-31	1-oxo-1h-thiazolo(3,2-a)pyrimidine-2-carboxamides
FR2522991B1 (fr)	1985-05-24
FR2521037B1 (fr)	1985-04-19
GR77488B (fr)	1984-09-24
FR2531499B3 (fr)	1985-05-03
ZA83626B (en)	1983-12-28	Substituted 9-(1 or 3-monoacyloxy or 1, 3-diacyloxy-2-propoxy-methyl purines as antiviral agent
GB8301394D0 (en)	1983-02-23	Wheel brace
FR2526705B1 (fr)	1985-03-29
GB8312333D0 (en)	1983-06-08	Wheels
IE820064L (en)	1982-08-26	2-oxa-bicyclo(3,3,0)octanes
AU87393S (en)	1983-08-08	Sulky wheel
AU2079183A (en)	1984-07-17	Dolly
IE822958L (en)	1983-06-15	Azabicyclo derivatives.
GR69500B (fr)	1982-06-25