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MXPA03010702A - Suministro de compuestos para el tratamiento de migrana a traves de una ruta d einhalacion. - Google Patents

Suministro de compuestos para el tratamiento de migrana a traves de una ruta d einhalacion.

Info

Publication number
MXPA03010702A
MXPA03010702A MXPA03010702A MXPA03010702A MXPA03010702A MX PA03010702 A MXPA03010702 A MX PA03010702A MX PA03010702 A MXPA03010702 A MX PA03010702A MX PA03010702 A MXPA03010702 A MX PA03010702A MX PA03010702 A MXPA03010702 A MX PA03010702A
Authority
MX
Mexico
Prior art keywords
migraine
drug
mammal
route
composition
Prior art date
Application number
MXPA03010702A
Other languages
English (en)
Inventor
D Rabinowitz Joshua
Original Assignee
Alexza Molecular Delivery Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alexza Molecular Delivery Corp filed Critical Alexza Molecular Delivery Corp
Priority claimed from PCT/US2002/016348 external-priority patent/WO2002094241A1/en
Publication of MXPA03010702A publication Critical patent/MXPA03010702A/es

Links

Classifications

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    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
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    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
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    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24—HEATING; RANGES; VENTILATING
    • F24V—COLLECTION, PRODUCTION OR USE OF HEAT NOT OTHERWISE PROVIDED FOR
    • F24V30/00—Apparatus or devices using heat produced by exothermal chemical reactions other than combustion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/04—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised
    • A61M11/041—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters
    • A61M11/042—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters electrical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8206—Internal energy supply devices battery-operated

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Abstract

La presente invencion se refiere al suministro de un farmaco para migrana a traves de una ruta de inhalacion. Especificamente se refiere a aerosoles que contienen un farmaco para migrana que son utilizados en terapia de inhalacion. En un aspecto de composicion de la presente invencion, el aerosol comprende particulas que comprenden por lo menos 5% en peso de un farmaco para migrana. En un aspecto del metodo de la presente invencion, un farmaco para migrana es suministrado a un mamifero a traves de una ruta de inhalacion. El metodo comprende: a) calentar una composicion, en donde la composicion comprende por lo menos 5% en peso de un farmaco para migrana, para formar un vapor, y, b) dejar que el vapor se enfrie, formando asi un aerosol de condensacion comprendiendo particulas, que es inhalado por el mamifero. En un aspecto de equipo de la presente invencion, se proporciona un equipo para suministrar un farmaco para migrana a traves de una ruta de inhalacion a un mamifero, el cual comprende: a) una composicion que comprende por lo menos 5% de un farmaco para migrana; y b) un dispositivo que forma un aerosol que contiene farmaco para migrana a partir de la composicion, para inhalacion por el mamifero.
MXPA03010702A 2001-05-24 2002-05-23 Suministro de compuestos para el tratamiento de migrana a traves de una ruta d einhalacion. MXPA03010702A (es)

Applications Claiming Priority (3)

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US29420301P 2001-05-24 2001-05-24
US31747901P 2001-09-05 2001-09-05
PCT/US2002/016348 WO2002094241A1 (en) 2001-05-24 2002-05-23 Delivery of compounds for the treatment of migraine through an inhalation route

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MXPA03010703A MXPA03010703A (es) 2001-05-24 2002-05-20 Suministro de ant-psicoticos a traves de una ruta de inhalacion.
MXPA03010702A MXPA03010702A (es) 2001-05-24 2002-05-23 Suministro de compuestos para el tratamiento de migrana a traves de una ruta d einhalacion.

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EP (14) EP1392262A1 (es)
JP (7) JP2005503425A (es)
AT (11) ATE462420T1 (es)
AU (3) AU2002314784A1 (es)
BE (1) BE2013C054I2 (es)
CA (7) CA2446904A1 (es)
DE (4) DE60235851D1 (es)
DK (1) DK1389098T3 (es)
ES (5) ES2341594T3 (es)
FR (1) FR13C0051I1 (es)
MX (2) MXPA03010703A (es)
NZ (6) NZ529422A (es)
PL (3) PL363996A1 (es)
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DE60220909T2 (de) 2008-02-28
US20030017119A1 (en) 2003-01-23
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US20060251587A1 (en) 2006-11-09
ES2341594T3 (es) 2010-06-22
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US20050089479A1 (en) 2005-04-28
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