MXPA02003891A - Portador objetivado magnetico, compuesto de hierro y materiales porosos, para la entrega de agentes biologicamente activos. - Google Patents
Portador objetivado magnetico, compuesto de hierro y materiales porosos, para la entrega de agentes biologicamente activos.Info
- Publication number
- MXPA02003891A MXPA02003891A MXPA02003891A MXPA02003891A MXPA02003891A MX PA02003891 A MXPA02003891 A MX PA02003891A MX PA02003891 A MXPA02003891 A MX PA02003891A MX PA02003891 A MXPA02003891 A MX PA02003891A MX PA02003891 A MXPA02003891 A MX PA02003891A
- Authority
- MX
- Mexico
- Prior art keywords
- particles
- iron
- ceramic
- biologically active
- composition
- Prior art date
Links
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- 230000009871 nonspecific binding Effects 0.000 description 1
- 239000002773 nucleotide Substances 0.000 description 1
- 125000003729 nucleotide group Chemical group 0.000 description 1
- FPLYNRPOIZEADP-UHFFFAOYSA-N octylsilane Chemical compound CCCCCCCC[SiH3] FPLYNRPOIZEADP-UHFFFAOYSA-N 0.000 description 1
- 229940127240 opiate Drugs 0.000 description 1
- TWNQGVIAIRXVLR-UHFFFAOYSA-N oxo(oxoalumanyloxy)alumane Chemical compound O=[Al]O[Al]=O TWNQGVIAIRXVLR-UHFFFAOYSA-N 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 238000003921 particle size analysis Methods 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical compound [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 description 1
- 239000012071 phase Substances 0.000 description 1
- PARWUHTVGZSQPD-UHFFFAOYSA-N phenylsilane Chemical compound [SiH3]C1=CC=CC=C1 PARWUHTVGZSQPD-UHFFFAOYSA-N 0.000 description 1
- 150000003904 phospholipids Chemical class 0.000 description 1
- 230000008288 physiological mechanism Effects 0.000 description 1
- 239000013612 plasmid Substances 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 108091033319 polynucleotide Proteins 0.000 description 1
- 102000040430 polynucleotide Human genes 0.000 description 1
- 239000002157 polynucleotide Substances 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 229940063238 premarin Drugs 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000000651 prodrug Substances 0.000 description 1
- 229940002612 prodrug Drugs 0.000 description 1
- 239000000583 progesterone congener Substances 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 125000001453 quaternary ammonium group Chemical group 0.000 description 1
- MCJGNVYPOGVAJF-UHFFFAOYSA-N quinolin-8-ol Chemical compound C1=CN=C2C(O)=CC=CC2=C1 MCJGNVYPOGVAJF-UHFFFAOYSA-N 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- 238000001959 radiotherapy Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000004043 responsiveness Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 238000001878 scanning electron micrograph Methods 0.000 description 1
- 239000000932 sedative agent Substances 0.000 description 1
- 229940125723 sedative agent Drugs 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 229910000077 silane Inorganic materials 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 229930002534 steroid glycoside Natural products 0.000 description 1
- 150000008143 steroidal glycosides Chemical class 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 229920002994 synthetic fiber Polymers 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 229960001712 testosterone propionate Drugs 0.000 description 1
- GBNXLQPMFAUCOI-UHFFFAOYSA-H tetracalcium;oxygen(2-);diphosphate Chemical compound [O-2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O GBNXLQPMFAUCOI-UHFFFAOYSA-H 0.000 description 1
- 210000001685 thyroid gland Anatomy 0.000 description 1
- 230000007675 toxicity by organ Effects 0.000 description 1
- 231100000155 toxicity by organ Toxicity 0.000 description 1
- AEGSYIKLTCZUEZ-FZTWWWDYSA-K tri(quinolin-8-yloxy)indigane Chemical compound [111In+3].C1=CN=C2C([O-])=CC=CC2=C1.C1=CN=C2C([O-])=CC=CC2=C1.C1=CN=C2C([O-])=CC=CC2=C1 AEGSYIKLTCZUEZ-FZTWWWDYSA-K 0.000 description 1
- 229910000391 tricalcium phosphate Inorganic materials 0.000 description 1
- 235000019731 tricalcium phosphate Nutrition 0.000 description 1
- 229940078499 tricalcium phosphate Drugs 0.000 description 1
- PQDJYEQOELDLCP-UHFFFAOYSA-N trimethylsilane Chemical compound C[SiH](C)C PQDJYEQOELDLCP-UHFFFAOYSA-N 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
- 229910052882 wollastonite Inorganic materials 0.000 description 1
- 239000010456 wollastonite Substances 0.000 description 1
- 239000010457 zeolite Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5094—Microcapsules containing magnetic carrier material, e.g. ferrite for drug targeting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
- A61K47/6923—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being an inorganic particle, e.g. ceramic particles, silica particles, ferrite or synsorb
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Ceramic Engineering (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Materials For Medical Uses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Paints Or Removers (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16029399P | 1999-10-18 | 1999-10-18 | |
| PCT/US2000/028615 WO2001028587A2 (fr) | 1999-10-18 | 2000-10-13 | Porteurs magnetiques cibles composes de fer et de matieres poreuses pour l'administration ciblee d'agents biologiquement actifs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA02003891A true MXPA02003891A (es) | 2002-12-09 |
Family
ID=22576298
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA02003891A MXPA02003891A (es) | 1999-10-18 | 2000-10-13 | Portador objetivado magnetico, compuesto de hierro y materiales porosos, para la entrega de agentes biologicamente activos. |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP1221974A2 (fr) |
| JP (3) | JP2003512336A (fr) |
| KR (1) | KR20020064299A (fr) |
| CN (1) | CN1287859C (fr) |
| AU (1) | AU772755B2 (fr) |
| BR (1) | BR0014877A (fr) |
| CA (1) | CA2387925A1 (fr) |
| CZ (1) | CZ293919B6 (fr) |
| DE (1) | DE1221974T1 (fr) |
| ES (1) | ES2182731T1 (fr) |
| HK (1) | HK1045110A1 (fr) |
| IL (1) | IL149004A0 (fr) |
| MX (1) | MXPA02003891A (fr) |
| NZ (1) | NZ518311A (fr) |
| WO (1) | WO2001028587A2 (fr) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9808052D0 (en) | 1998-04-17 | 1998-06-17 | Secr Defence | Implants for administering substances and methods of producing implants |
| AU2004272081A1 (en) * | 2003-09-12 | 2005-03-24 | Bankruptcy Estate Of Ferx, Inc. | Magnetically targetable particles comprising magnetic components and biocompatible polymers for site-specific delivery of biologically active agents |
| JP2007001865A (ja) * | 2003-09-16 | 2007-01-11 | Ltt Bio-Pharma Co Ltd | 脂溶性薬物封入微粒子、その製造法およびそれを含有する製剤 |
| JP4982084B2 (ja) * | 2004-02-09 | 2012-07-25 | 株式会社サンギ | 抗腫瘍剤 |
| AU2005215234B2 (en) * | 2004-02-20 | 2009-02-19 | Algeta As | Alpha-emitting Hydroxyapatite particles |
| GB0403856D0 (en) * | 2004-02-20 | 2004-03-24 | Algeta As | Composition |
| JP2006199810A (ja) * | 2005-01-20 | 2006-08-03 | Yokohama National Univ | 複合粒子およびその製造方法 |
| WO2006109635A1 (fr) | 2005-04-06 | 2006-10-19 | Kabushiki Kaisha Sangi | Agent anti-tumeur absorbable par l’intestin |
| AU2010246067B2 (en) | 2009-05-04 | 2016-07-07 | Eyepoint Pharmaceuticals Us, Inc. | Porous silicon drug-eluting particles |
| CN104586742A (zh) | 2010-11-01 | 2015-05-06 | 普西维达公司 | 用于递送治疗剂的可生物侵蚀的硅基装置 |
| WO2014035090A1 (fr) * | 2012-08-28 | 2014-03-06 | 주식회사 바이오큐브시스템 | Phase solide poreuse pour isoler rapidement des molécules biologiques pour une réaction d'amplification d'acides nucléiques à partir d'un échantillon biologique et son utilisation |
| CN105025928A (zh) | 2013-03-15 | 2015-11-04 | 普西维达公司 | 用于递送治疗剂的可生物蚀解的硅基组合物 |
| JP6443907B2 (ja) * | 2014-02-17 | 2018-12-26 | 浩文 山本 | 造影剤の腫瘍への集積を促進するための集積促進剤 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4243652A (en) * | 1978-07-14 | 1981-01-06 | The Procter & Gamble Company | Gastrointestinal scanning agent |
| ES2066851T3 (es) * | 1988-05-24 | 1995-03-16 | Anagen Uk Ltd | Particulas atraibles magneticamente y metodo de preparacion. |
| EP0772776B1 (fr) * | 1994-07-27 | 2000-03-22 | Herbert Dr. Pilgrimm | Particules superparamagnetiques, leur procede de production et leur utilisation |
| WO1997001304A1 (fr) * | 1995-06-29 | 1997-01-16 | Mallinckrodt Medical, Inc. | Particules d'apatite radiomarquees contenant un ion paramagnetique |
| JP3735990B2 (ja) * | 1997-01-28 | 2006-01-18 | 東ソー株式会社 | 磁性シリカゲルの製造方法 |
-
2000
- 2000-10-13 BR BR0014877-6A patent/BR0014877A/pt not_active IP Right Cessation
- 2000-10-13 WO PCT/US2000/028615 patent/WO2001028587A2/fr not_active Ceased
- 2000-10-13 MX MXPA02003891A patent/MXPA02003891A/es not_active Application Discontinuation
- 2000-10-13 HK HK02106551.6A patent/HK1045110A1/zh unknown
- 2000-10-13 NZ NZ518311A patent/NZ518311A/en unknown
- 2000-10-13 KR KR1020027004933A patent/KR20020064299A/ko not_active Ceased
- 2000-10-13 CZ CZ20021357A patent/CZ293919B6/cs not_active IP Right Cessation
- 2000-10-13 AU AU10905/01A patent/AU772755B2/en not_active Ceased
- 2000-10-13 IL IL14900400A patent/IL149004A0/xx unknown
- 2000-10-13 CA CA002387925A patent/CA2387925A1/fr not_active Abandoned
- 2000-10-13 EP EP00972209A patent/EP1221974A2/fr not_active Withdrawn
- 2000-10-13 ES ES00972209T patent/ES2182731T1/es active Pending
- 2000-10-13 JP JP2001531415A patent/JP2003512336A/ja active Pending
- 2000-10-13 CN CNB008173796A patent/CN1287859C/zh not_active Expired - Fee Related
- 2000-10-13 DE DE1221974T patent/DE1221974T1/de active Pending
-
2003
- 2003-03-10 JP JP2003063821A patent/JP2003321348A/ja not_active Withdrawn
-
2005
- 2005-03-28 JP JP2005093293A patent/JP2005200426A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CZ20021357A3 (cs) | 2002-11-13 |
| CA2387925A1 (fr) | 2001-04-26 |
| WO2001028587A3 (fr) | 2002-01-03 |
| AU1090501A (en) | 2001-04-30 |
| KR20020064299A (ko) | 2002-08-07 |
| WO2001028587A2 (fr) | 2001-04-26 |
| ES2182731T1 (es) | 2003-03-16 |
| IL149004A0 (en) | 2002-11-10 |
| HK1045110A1 (zh) | 2002-11-15 |
| CN1287859C (zh) | 2006-12-06 |
| EP1221974A2 (fr) | 2002-07-17 |
| DE1221974T1 (de) | 2003-02-06 |
| JP2003321348A (ja) | 2003-11-11 |
| JP2003512336A (ja) | 2003-04-02 |
| BR0014877A (pt) | 2002-06-11 |
| CN1420787A (zh) | 2003-05-28 |
| AU772755B2 (en) | 2004-05-06 |
| NZ518311A (en) | 2003-10-31 |
| JP2005200426A (ja) | 2005-07-28 |
| CZ293919B6 (cs) | 2004-08-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |