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MX2018006181A - Inhibidores de fgfr2 solos o en combinacion con agentes que estimulan el sistema inmunitario en el tratamiento contra el cancer. - Google Patents

Inhibidores de fgfr2 solos o en combinacion con agentes que estimulan el sistema inmunitario en el tratamiento contra el cancer.

Info

Publication number
MX2018006181A
MX2018006181A MX2018006181A MX2018006181A MX2018006181A MX 2018006181 A MX2018006181 A MX 2018006181A MX 2018006181 A MX2018006181 A MX 2018006181A MX 2018006181 A MX2018006181 A MX 2018006181A MX 2018006181 A MX2018006181 A MX 2018006181A
Authority
MX
Mexico
Prior art keywords
fgfr2
stimulate
agents
combination
immune system
Prior art date
Application number
MX2018006181A
Other languages
English (en)
Inventor
Pierce Kristen
Sikorski Robert
Powers Janine
Palencia Servando
Ghoddusi Majid
Krishnan Kartik
Original Assignee
Five Prime Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Five Prime Therapeutics Inc filed Critical Five Prime Therapeutics Inc
Publication of MX2018006181A publication Critical patent/MX2018006181A/es

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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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Abstract

En la presente se proporcionan usos de inhibidores del receptor 2 del factor de crecimiento de fibroblastos (FGFR2) en el tratamiento contra el cáncer, en algunos casos en combinación con agentes que estimulan el sistema inmunitario, tales como inhibidores de PD-1 o PD-L1. En algunas modalidades, los inhibidores de FGFR2 pueden comprender anticuerpos de FGFR2 o polipéptidos de dominio extracelular (ECD) de FGFR2 o moléculas de fusión de ECD de FGFR2 que comprenden un ECD de FGFR2 y un compañero de fusión. En algunas modalidades, los inhibidores de PD-1/PD-L1 pueden comprender anticuerpos anti-PD-1 tales como anticuerpos que se unen a PD-1 o a PD-L1 e inhiben interacciones entre esas proteínas, así como polipéptidos o proteínas de fusión de PD-1.
MX2018006181A 2015-11-23 2016-11-22 Inhibidores de fgfr2 solos o en combinacion con agentes que estimulan el sistema inmunitario en el tratamiento contra el cancer. MX2018006181A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562258731P 2015-11-23 2015-11-23
US201662314174P 2016-03-28 2016-03-28
US201662379094P 2016-08-24 2016-08-24
PCT/US2016/063332 WO2017091577A1 (en) 2015-11-23 2016-11-22 Fgfr2 inhibitors alone or in combination with immune stimulating agents in cancer treatment

Publications (1)

Publication Number Publication Date
MX2018006181A true MX2018006181A (es) 2018-09-24

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MX2018006181A MX2018006181A (es) 2015-11-23 2016-11-22 Inhibidores de fgfr2 solos o en combinacion con agentes que estimulan el sistema inmunitario en el tratamiento contra el cancer.
MX2022013192A MX2022013192A (es) 2015-11-23 2018-05-18 Inhibidores de fgfr2 solos o en combinacion con agentes que estimulan el sistema inmunitario en el tratamiento contra el cancer.

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MX2022013192A MX2022013192A (es) 2015-11-23 2018-05-18 Inhibidores de fgfr2 solos o en combinacion con agentes que estimulan el sistema inmunitario en el tratamiento contra el cancer.

Country Status (14)

Country Link
US (4) US11447553B2 (es)
EP (1) EP3380523A1 (es)
JP (3) JP7349787B2 (es)
KR (2) KR102777244B1 (es)
CN (2) CN108368174B (es)
AU (2) AU2016359609B2 (es)
BR (1) BR112018010410A8 (es)
CA (1) CA3004794A1 (es)
IL (2) IL291926B2 (es)
MX (2) MX2018006181A (es)
RU (1) RU2745707C2 (es)
SG (2) SG11201804134YA (es)
TW (2) TWI791422B (es)
WO (2) WO2017091577A1 (es)

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