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MX2013012598A - Nanoportadores sintéticos tolerogénicos para eliminar linfocitos t efectores específicos para un antígeno. - Google Patents

Nanoportadores sintéticos tolerogénicos para eliminar linfocitos t efectores específicos para un antígeno.

Info

Publication number
MX2013012598A
MX2013012598A MX2013012598A MX2013012598A MX2013012598A MX 2013012598 A MX2013012598 A MX 2013012598A MX 2013012598 A MX2013012598 A MX 2013012598A MX 2013012598 A MX2013012598 A MX 2013012598A MX 2013012598 A MX2013012598 A MX 2013012598A
Authority
MX
Mexico
Prior art keywords
antigen
nanopporters
specific effectors
synthetic
tolerogenic
Prior art date
Application number
MX2013012598A
Other languages
English (en)
Inventor
Christopher Fraser
Roberto A Maldonado
Takashi Kei Kishimoto
Original Assignee
Selecta Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Selecta Biosciences Inc filed Critical Selecta Biosciences Inc
Publication of MX2013012598A publication Critical patent/MX2013012598A/es

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    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
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Abstract

Se divulgan métodos de nanoportador sintético, y composiciones relacionadas, que comprenden administrar inmunosupresores y epítopes restringidos por MHC de Clase I y/o MHC de Clase II que pueden generar inmunorrespuestas tolerogénicas (por ejemplo, eliminación específica de antígeno de células efectoras T).
MX2013012598A 2011-04-29 2012-04-27 Nanoportadores sintéticos tolerogénicos para eliminar linfocitos t efectores específicos para un antígeno. MX2013012598A (es)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US201161480946P 2011-04-29 2011-04-29
US201161513514P 2011-07-29 2011-07-29
US201161531175P 2011-09-06 2011-09-06
US201161531209P 2011-09-06 2011-09-06
US201161531164P 2011-09-06 2011-09-06
US201161531168P 2011-09-06 2011-09-06
US201161531194P 2011-09-06 2011-09-06
US201161531153P 2011-09-06 2011-09-06
US201161531215P 2011-09-06 2011-09-06
US201161531180P 2011-09-06 2011-09-06
US201161531204P 2011-09-06 2011-09-06
US201161531147P 2011-09-06 2011-09-06
PCT/US2012/035555 WO2012149393A2 (en) 2011-04-29 2012-04-27 Tolerogenic synthetic nanocarriers for antigen-specific deletion of t effector cells

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MX2013012598A true MX2013012598A (es) 2014-08-18

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MX2013012598A MX2013012598A (es) 2011-04-29 2012-04-27 Nanoportadores sintéticos tolerogénicos para eliminar linfocitos t efectores específicos para un antígeno.
MX2013012597A MX2013012597A (es) 2011-04-29 2012-04-27 Nanoportadores sintéticos tolerogénicos para inducir linfocitos b reguladores.
MX2013012592A MX374700B (es) 2011-04-29 2012-04-27 Nanoportadores sintéticos tolerogénicos para reducir las respuestas inmunitarias a proteínas terapéuticas.
MX2013012595A MX373641B (es) 2011-04-29 2012-04-27 Nanoportadores sintéticos tolerogénicos para la terapia contra alergias.
MX2013012594A MX2013012594A (es) 2011-04-29 2012-04-27 Nanoportadores sintéticos tolerogénicos para reducir las respuestas de linfocitos t citotóxicos.
MX2013012593A MX374963B (es) 2011-04-29 2012-04-27 Nanoportadores sintéticos tolerogénicos para reducir las respuestas de anticuerpos.
MX2013012599A MX2013012599A (es) 2011-04-29 2012-04-27 Liberación controlada de inmunosupresores a partir de nanoportadores sintéticos.
MX2013012596A MX2013012596A (es) 2011-04-29 2012-04-27 Nanoportadores sintéticos tolerogénicos para generar linfocitos t reguladores cd8+.
MX2013012591A MX377068B (es) 2011-04-29 2012-04-27 Nanoportadores sintéticos tolerogénicos.
MX2019011890A MX2019011890A (es) 2011-04-29 2013-10-28 Liberacion controlada de inmunosupresores a partir de nanoportadores sinteticos.
MX2020004906A MX2020004906A (es) 2011-04-29 2013-10-28 Nanoportadores sinteticos tolerogenicos.
MX2019013515A MX2019013515A (es) 2011-04-29 2013-10-28 Nanoportadores sinteticos tolerogenicos para reducir las respuestas de anticuerpos.
MX2019013118A MX2019013118A (es) 2011-04-29 2013-10-28 Nanoportadores sinteticos tolerogenicos para reducir las respuestas inmunitarias a proteinas terapeuticas.

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MX2013012597A MX2013012597A (es) 2011-04-29 2012-04-27 Nanoportadores sintéticos tolerogénicos para inducir linfocitos b reguladores.
MX2013012592A MX374700B (es) 2011-04-29 2012-04-27 Nanoportadores sintéticos tolerogénicos para reducir las respuestas inmunitarias a proteínas terapéuticas.
MX2013012595A MX373641B (es) 2011-04-29 2012-04-27 Nanoportadores sintéticos tolerogénicos para la terapia contra alergias.
MX2013012594A MX2013012594A (es) 2011-04-29 2012-04-27 Nanoportadores sintéticos tolerogénicos para reducir las respuestas de linfocitos t citotóxicos.
MX2013012593A MX374963B (es) 2011-04-29 2012-04-27 Nanoportadores sintéticos tolerogénicos para reducir las respuestas de anticuerpos.
MX2013012599A MX2013012599A (es) 2011-04-29 2012-04-27 Liberación controlada de inmunosupresores a partir de nanoportadores sintéticos.
MX2013012596A MX2013012596A (es) 2011-04-29 2012-04-27 Nanoportadores sintéticos tolerogénicos para generar linfocitos t reguladores cd8+.
MX2013012591A MX377068B (es) 2011-04-29 2012-04-27 Nanoportadores sintéticos tolerogénicos.
MX2019011890A MX2019011890A (es) 2011-04-29 2013-10-28 Liberacion controlada de inmunosupresores a partir de nanoportadores sinteticos.
MX2020004906A MX2020004906A (es) 2011-04-29 2013-10-28 Nanoportadores sinteticos tolerogenicos.
MX2019013515A MX2019013515A (es) 2011-04-29 2013-10-28 Nanoportadores sinteticos tolerogenicos para reducir las respuestas de anticuerpos.
MX2019013118A MX2019013118A (es) 2011-04-29 2013-10-28 Nanoportadores sinteticos tolerogenicos para reducir las respuestas inmunitarias a proteinas terapeuticas.

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EP (15) EP3760201A1 (es)
JP (32) JP6422773B2 (es)
KR (26) KR20140029469A (es)
CN (34) CN103491957A (es)
AU (34) AU2012249567B2 (es)
BR (5) BR112013027508A2 (es)
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EA (16) EA027103B1 (es)
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HU (1) HUE050142T2 (es)
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US9993548B2 (en) 2018-06-12
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MX374963B (es) 2025-03-06
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CN113018452A (zh) 2021-06-25
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IL297146A (en) 2022-12-01
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WO2012149393A9 (en) 2013-01-24
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EA201692374A3 (ru) 2017-08-31
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WO2012149301A3 (en) 2013-01-31
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AU2017204814A1 (en) 2017-07-27
CN118078979A (zh) 2024-05-28
EP3682877A1 (en) 2020-07-22
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WO2012149454A2 (en) 2012-11-01
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AU2012249567A1 (en) 2013-10-31
KR20230106708A (ko) 2023-07-13
KR102674640B1 (ko) 2024-06-13
AU2019232928A1 (en) 2019-10-10
JP7242519B2 (ja) 2023-03-20
KR102112002B1 (ko) 2020-05-18
KR102344744B1 (ko) 2021-12-30
US20120276156A1 (en) 2012-11-01
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CA3182519A1 (en) 2012-11-01
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WO2012149265A2 (en) 2012-11-01
AU2017245402B2 (en) 2019-10-17
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US9987354B2 (en) 2018-06-05
IL228934A0 (en) 2013-12-31
JP2017122111A (ja) 2017-07-13
JP2020073496A (ja) 2020-05-14
AU2017203655A1 (en) 2017-06-15
IL228932B2 (en) 2023-03-01
EA201391597A1 (ru) 2014-09-30
CN107670054A (zh) 2018-02-09
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IL283728B2 (en) 2024-01-01
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BR112013027508A2 (pt) 2017-03-14
CA2834514A1 (en) 2012-11-01
CN117065050A (zh) 2023-11-17
CN103501787A (zh) 2014-01-08
KR20220026601A (ko) 2022-03-04
US20150320884A1 (en) 2015-11-12
KR102283951B1 (ko) 2021-08-02
AU2012249553A1 (en) 2013-10-24
AU2017244514A1 (en) 2017-11-02
CN107261154A (zh) 2017-10-20
JP7389549B2 (ja) 2023-11-30
US20120276155A1 (en) 2012-11-01
US10004802B2 (en) 2018-06-26
JP6491879B2 (ja) 2019-03-27
EP2704715A4 (en) 2015-03-04
EA027380B1 (ru) 2017-07-31
BR112013027500A2 (pt) 2017-01-10
JP2021183616A (ja) 2021-12-02
US9265815B2 (en) 2016-02-23
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KR20240116583A (ko) 2024-07-29

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