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MX2010000846A - Diagnostico de aneuploide cromosomico fetal mediante el uso de secuenciacion genomica. - Google Patents

Diagnostico de aneuploide cromosomico fetal mediante el uso de secuenciacion genomica.

Info

Publication number
MX2010000846A
MX2010000846A MX2010000846A MX2010000846A MX2010000846A MX 2010000846 A MX2010000846 A MX 2010000846A MX 2010000846 A MX2010000846 A MX 2010000846A MX 2010000846 A MX2010000846 A MX 2010000846A MX 2010000846 A MX2010000846 A MX 2010000846A
Authority
MX
Mexico
Prior art keywords
chromosomal aneuploidy
fetal chromosomal
genomic sequencing
sequenced
diagnosing fetal
Prior art date
Application number
MX2010000846A
Other languages
English (en)
Inventor
Kwan Chee Chan
Rossa Wai Kwun Chiu
Yuk-Ming Dennis Lo
Original Assignee
Univ Hong Kong Chinese
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39798126&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2010000846(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Hong Kong Chinese filed Critical Univ Hong Kong Chinese
Publication of MX2010000846A publication Critical patent/MX2010000846A/es

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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/10—Ploidy or copy number detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/38—Pediatrics
    • G01N2800/385—Congenital anomalies
    • G01N2800/387—Down syndrome; Trisomy 18; Trisomy 13
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
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  • Molecular Biology (AREA)
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  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Informatics (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Las modalidades de esta invenci?n proporcionan m?todos, sistemas, y un aparato para determinar si una aneuploid?a cromos?mica fetal existe en una muestra biol?gica obtenida de un sexo femenino embarazado. Las mol?culas de ?cido nucleico de la muestra biol?gica son secuenciadas, de modo que una fracci?n del genoma sea secuenciada. Las cantidades respectivas de un cromosoma cl?nicamente relevante y de cromosomas de referencia se determinan de resultados de la secuenciaci?n. Un par?metro derivado de estas cantidades (p.ej una proporci?n) se compara con unos o m?s valores de l?mite, determinando as? una clasificaci?n de si existe una aneuploid?a cromos?mica fetal.
MX2010000846A 2007-07-23 2008-07-23 Diagnostico de aneuploide cromosomico fetal mediante el uso de secuenciacion genomica. MX2010000846A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US95143807P 2007-07-23 2007-07-23
PCT/GB2008/002530 WO2009013496A1 (en) 2007-07-23 2008-07-23 Diagnosing fetal chromosomal aneuploidy using genomic sequencing

Publications (1)

Publication Number Publication Date
MX2010000846A true MX2010000846A (es) 2010-04-21

Family

ID=39798126

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2010000846A MX2010000846A (es) 2007-07-23 2008-07-23 Diagnostico de aneuploide cromosomico fetal mediante el uso de secuenciacion genomica.
MX2014006579A MX341573B (es) 2007-07-23 2008-07-23 Diagnostico de aneuploide cromosomico fetal mediante el uso de secuenciacion genomica.
MX2014006501A MX346069B (es) 2007-07-23 2008-07-23 Diagnóstico de aneuploide cromosómico fetal mediante el uso de secuenciación genómica.

Family Applications After (2)

Application Number Title Priority Date Filing Date
MX2014006579A MX341573B (es) 2007-07-23 2008-07-23 Diagnostico de aneuploide cromosomico fetal mediante el uso de secuenciacion genomica.
MX2014006501A MX346069B (es) 2007-07-23 2008-07-23 Diagnóstico de aneuploide cromosómico fetal mediante el uso de secuenciación genómica.

Country Status (26)

Country Link
US (12) US8706422B2 (es)
EP (15) EP2557519B1 (es)
JP (17) JP5736170B2 (es)
KR (24) KR20220146689A (es)
CN (11) CN106834481A (es)
AU (1) AU2008278839B2 (es)
BR (1) BRPI0814670B8 (es)
CA (10) CA2693081C (es)
CY (3) CY1114773T1 (es)
DK (6) DK2557520T3 (es)
EA (6) EA201201551A1 (es)
ES (7) ES2820866T3 (es)
FI (1) FI2557517T3 (es)
HK (2) HK1199067A1 (es)
HR (4) HRP20140009T4 (es)
HU (3) HUE030510T2 (es)
IL (2) IL203311A (es)
LT (2) LT2557517T (es)
MX (3) MX2010000846A (es)
NZ (2) NZ600407A (es)
PL (4) PL2557520T3 (es)
PT (3) PT2557520T (es)
SG (1) SG183062A1 (es)
SI (4) SI2557517T1 (es)
WO (2) WO2009013492A1 (es)
ZA (1) ZA201000524B (es)

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