MX2009009952A - Sal clorhidrato de 5-[3-(3-hidroxifenoxi)azetidin-1-il]-5-metil-2, 2-difenilhexanamida. - Google Patents
Sal clorhidrato de 5-[3-(3-hidroxifenoxi)azetidin-1-il]-5-metil-2, 2-difenilhexanamida.Info
- Publication number
- MX2009009952A MX2009009952A MX2009009952A MX2009009952A MX2009009952A MX 2009009952 A MX2009009952 A MX 2009009952A MX 2009009952 A MX2009009952 A MX 2009009952A MX 2009009952 A MX2009009952 A MX 2009009952A MX 2009009952 A MX2009009952 A MX 2009009952A
- Authority
- MX
- Mexico
- Prior art keywords
- diphenylhexanamide
- hydrochloride salt
- tivdroxyphenoxy
- azetidiï
- ethyl
- Prior art date
Links
- QCQCHGYLTSGIGX-GHXANHINSA-N 4-[[(3ar,5ar,5br,7ar,9s,11ar,11br,13as)-5a,5b,8,8,11a-pentamethyl-3a-[(5-methylpyridine-3-carbonyl)amino]-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3h-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid Chemical compound N([C@@]12CC[C@@]3(C)[C@]4(C)CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(O)=O)CC[C@]5(C)[C@H]4CC[C@@H]3C1=C(C(C2)=O)C(C)C)C(=O)C1=CN=CC(C)=C1 QCQCHGYLTSGIGX-GHXANHINSA-N 0.000 title abstract 2
- NYNKWHSUVKSVQL-UHFFFAOYSA-N 3-ethyl-2,2-diphenylhexanamide Chemical compound C(C)C(C(C(=O)N)(C1=CC=CC=C1)C1=CC=CC=C1)CCC NYNKWHSUVKSVQL-UHFFFAOYSA-N 0.000 title 1
- WGOJWDWKHJHXSV-UHFFFAOYSA-N 5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2-diphenylhexanamide Chemical compound C1C(OC=2C=C(O)C=CC=2)CN1C(C)(C)CCC(C(N)=O)(C=1C=CC=CC=1)C1=CC=CC=C1 WGOJWDWKHJHXSV-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Esta invención se refiere a la sal clorhidrato de 5-[3-(3-hidroxifenoxi)azetidin-1-il]-5-metil-2,2-difenilhexanamid a o forma derivada de la misma y a su uso como un medicamento.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89516307P | 2007-03-16 | 2007-03-16 | |
| PCT/IB2008/000622 WO2008135819A1 (en) | 2007-03-16 | 2008-03-06 | Hydrochloride salt of 5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2- diphenylhexanamide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009009952A true MX2009009952A (es) | 2009-10-08 |
Family
ID=39591485
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009009952A MX2009009952A (es) | 2007-03-16 | 2008-03-06 | Sal clorhidrato de 5-[3-(3-hidroxifenoxi)azetidin-1-il]-5-metil-2, 2-difenilhexanamida. |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US8263583B2 (es) |
| EP (1) | EP2125714B1 (es) |
| JP (1) | JP4277051B2 (es) |
| KR (1) | KR101120227B1 (es) |
| CN (2) | CN101641327A (es) |
| AR (1) | AR065714A1 (es) |
| AT (1) | ATE512132T1 (es) |
| AU (1) | AU2008247095B2 (es) |
| BR (1) | BRPI0808413A2 (es) |
| CA (1) | CA2678683C (es) |
| CY (1) | CY1111701T1 (es) |
| DK (1) | DK2125714T3 (es) |
| ES (1) | ES2364727T3 (es) |
| IL (1) | IL200403A (es) |
| MX (1) | MX2009009952A (es) |
| NZ (1) | NZ579056A (es) |
| PL (1) | PL2125714T3 (es) |
| PT (1) | PT2125714E (es) |
| RU (1) | RU2422439C2 (es) |
| SI (1) | SI2125714T1 (es) |
| TW (1) | TWI348907B (es) |
| WO (1) | WO2008135819A1 (es) |
| ZA (1) | ZA200906462B (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2010321738B2 (en) | 2009-11-23 | 2016-07-14 | Palatin Technologies, Inc. | Melanocortin-1 receptor-specific cyclic peptides |
| BR112012011780A2 (pt) | 2009-11-23 | 2019-09-24 | Palatin Technologies, Inc | peptídeo linear,composição farmacêutica,métodopara tratamento de umadoença,indicação,condição ou sídrome mediadsa por receptor de melanocortina emum mamífero humano ou não humano e método para tratamento de uma condição responsiva ás alterações em função de receptor de melanocortina em um mamifero humano ou não humano |
| EP2578570A1 (en) | 2011-10-07 | 2013-04-10 | Almirall, S.A. | Novel process for preparing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1(r)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one via novel intermediates of synthesis. |
| EP2641900A1 (en) | 2012-03-20 | 2013-09-25 | Almirall, S.A. | Novel polymorphic Crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one, heminapadisylate as agonist of the ß2 adrenergic receptor. |
| US20200031769A1 (en) | 2017-03-15 | 2020-01-30 | Mylan Laboratories Limited | Novel polymorphs of (5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2-diphenylhexanamide hydrochloride |
| PT3691620T (pt) | 2017-10-05 | 2022-10-06 | Fulcrum Therapeutics Inc | Os inibidores da quinase p38 reduzem a expressão de dux4 e genes a jusante para o tratamento de fshd |
| US10342786B2 (en) | 2017-10-05 | 2019-07-09 | Fulcrum Therapeutics, Inc. | P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD |
| EP3990091A4 (en) * | 2019-06-25 | 2023-07-12 | Mylan Laboratories Ltd. | METHODS AND INTERMEDIATES FOR THE PREPARATION OF 5-[3-(3-HYDROXYPHENOXY)AZETIDINE-1-YL]-5-METHYL-2,2-DIPHENYLHEXANAMIDE HYDROCHLORIDE SALT |
| US20230293430A1 (en) * | 2020-06-26 | 2023-09-21 | Mylan Pharma Uk Limited | Formulations including 5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2-diphenylhexanamide |
| CN113577059B (zh) * | 2021-08-02 | 2022-05-20 | 山东大学齐鲁医院(青岛) | 一种用于小儿哮喘的活性药物 |
| WO2025095813A1 (ru) * | 2023-11-03 | 2025-05-08 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Новые соединения |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUP0001118A3 (en) * | 1996-12-02 | 2001-06-28 | Kyorin Seiyaku Kk | N-substituted pyrrolidine derivatives, process for preparing the same and pharmaceutical compositions containing them |
| JPH11100366A (ja) | 1997-09-29 | 1999-04-13 | Kyorin Pharmaceut Co Ltd | 新規n−置換環状アミン誘導体及びその製造法 |
| DE10064398A1 (de) * | 2000-12-21 | 2002-06-27 | Aventis Pharma Gmbh | Neue Diphenylazetidinone, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
| EP1928821B1 (en) * | 2005-09-21 | 2009-01-07 | Pfizer Limited | Carboxamide derivatives as muscarinic receptor antagonists |
| JP2010504316A (ja) * | 2006-09-22 | 2010-02-12 | ファイザー・リミテッド | ムスカリン様受容体アンタゴニストとしてのアゼチジン誘導体 |
-
2008
- 2008-03-06 PT PT08719316T patent/PT2125714E/pt unknown
- 2008-03-06 NZ NZ579056A patent/NZ579056A/en not_active IP Right Cessation
- 2008-03-06 BR BRPI0808413-0A patent/BRPI0808413A2/pt not_active Application Discontinuation
- 2008-03-06 AT AT08719316T patent/ATE512132T1/de active
- 2008-03-06 PL PL08719316T patent/PL2125714T3/pl unknown
- 2008-03-06 EP EP08719316A patent/EP2125714B1/en active Active
- 2008-03-06 CN CN200880008581A patent/CN101641327A/zh active Pending
- 2008-03-06 WO PCT/IB2008/000622 patent/WO2008135819A1/en not_active Ceased
- 2008-03-06 MX MX2009009952A patent/MX2009009952A/es active IP Right Grant
- 2008-03-06 ES ES08719316T patent/ES2364727T3/es active Active
- 2008-03-06 AU AU2008247095A patent/AU2008247095B2/en active Active
- 2008-03-06 SI SI200830366T patent/SI2125714T1/sl unknown
- 2008-03-06 CN CN201310280277.XA patent/CN103351367B/zh active Active
- 2008-03-06 DK DK08719316.5T patent/DK2125714T3/da active
- 2008-03-06 US US12/530,573 patent/US8263583B2/en active Active
- 2008-03-06 RU RU2009134512/04A patent/RU2422439C2/ru active
- 2008-03-06 CA CA2678683A patent/CA2678683C/en active Active
- 2008-03-06 KR KR1020097019239A patent/KR101120227B1/ko not_active Expired - Fee Related
- 2008-03-13 AR ARP080101025A patent/AR065714A1/es not_active Application Discontinuation
- 2008-03-14 JP JP2008065066A patent/JP4277051B2/ja active Active
- 2008-03-14 TW TW097109223A patent/TWI348907B/zh not_active IP Right Cessation
-
2009
- 2009-08-13 IL IL200403A patent/IL200403A/en not_active IP Right Cessation
- 2009-09-16 ZA ZA200906462A patent/ZA200906462B/xx unknown
-
2011
- 2011-07-08 CY CY20111100664T patent/CY1111701T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |