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MX2009003567A - Procedimiento para la fabricacion de un compuesto cristalino de pirazolo[1,5-a]prirmidina. - Google Patents

Procedimiento para la fabricacion de un compuesto cristalino de pirazolo[1,5-a]prirmidina.

Info

Publication number
MX2009003567A
MX2009003567A MX2009003567A MX2009003567A MX2009003567A MX 2009003567 A MX2009003567 A MX 2009003567A MX 2009003567 A MX2009003567 A MX 2009003567A MX 2009003567 A MX2009003567 A MX 2009003567A MX 2009003567 A MX2009003567 A MX 2009003567A
Authority
MX
Mexico
Prior art keywords
pyrazolo
manufacture
crystalline
pyrim idine
compound
Prior art date
Application number
MX2009003567A
Other languages
English (en)
Inventor
Albert Palomer
Antonio Guglietta
Luis Anglada
Original Assignee
Ferrer Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrer Int filed Critical Ferrer Int
Publication of MX2009003567A publication Critical patent/MX2009003567A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La presente invención se refiere a un nuevo procedimiento para la fabricación industrial del polimorfo B de N-{2-fluoro-5-[3-(tiofen o-2-carbonil)-pirazolo[1,5-a]pirimidin-7-il]-fenil}-N-metil-aceta mida.
MX2009003567A 2006-10-11 2007-10-10 Procedimiento para la fabricacion de un compuesto cristalino de pirazolo[1,5-a]prirmidina. MX2009003567A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85101106P 2006-10-11 2006-10-11
EP06122143A EP1956021A1 (en) 2006-10-11 2006-10-11 Process for the manufacture of a crystalline pyrazolo[1,5-a]pyrimidine compound
PCT/EP2007/060796 WO2008043799A1 (en) 2006-10-11 2007-10-10 Process for the manufacture of a crystalline pyrazolo[1,5-a]pyrimidine compound

Publications (1)

Publication Number Publication Date
MX2009003567A true MX2009003567A (es) 2009-04-14

Family

ID=37808282

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009003567A MX2009003567A (es) 2006-10-11 2007-10-10 Procedimiento para la fabricacion de un compuesto cristalino de pirazolo[1,5-a]prirmidina.

Country Status (23)

Country Link
US (1) US8008486B2 (es)
EP (2) EP1956021A1 (es)
JP (1) JP5270555B2 (es)
KR (1) KR101409573B1 (es)
CN (1) CN101573362B (es)
AR (1) AR065831A1 (es)
AT (1) ATE503758T1 (es)
AU (1) AU2007306318B2 (es)
BR (1) BRPI0717836A2 (es)
CA (1) CA2664900C (es)
CL (1) CL2007002929A1 (es)
DE (1) DE602007013596D1 (es)
DK (1) DK2081934T3 (es)
ES (1) ES2362631T3 (es)
MX (1) MX2009003567A (es)
NO (1) NO342009B1 (es)
PL (1) PL2081934T3 (es)
PT (1) PT2081934E (es)
RU (1) RU2404984C1 (es)
SI (1) SI2081934T1 (es)
TW (1) TWI425000B (es)
UY (1) UY30619A1 (es)
WO (1) WO2008043799A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1884516A1 (en) * 2006-08-04 2008-02-06 Ferrer Internacional, S.A. Pyrazolo[1,5-a]pyrimidines, processes, uses and compositions

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6399621B1 (en) * 1999-08-10 2002-06-04 American Cyanamid Company N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1, 5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
NZ517298A (en) * 1999-09-02 2004-01-30 Neurocrine Biosciences Inc Polymorphs of N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-alpha]-pyrimidin-7-yl}phenyl)acetamide using for treating insomnia
WO2002012244A2 (en) * 2000-08-03 2002-02-14 Wyeth Polymorphs of zaleplon and methods for the preparation thereof
ES2274260T3 (es) * 2002-08-26 2007-05-16 Neurocrine Biosciences, Inc. Nuevo polimorfo de n-metil-n-(3-(3-((2-tienilcarbonil))pirazol-((1,5-alfa))pirimidin-7-il))fenil)acetamida y composiciones y metodos relacionados.
ES2222813B1 (es) 2003-07-24 2005-12-16 Ferrer Internacional, S.A. N-(3-(3-sustituidas-pirazolo(1,5-a)pirimidin-7-il)-fenil)-sulfonamidas y composiciones y metodos relacionados.
US20060064488A1 (en) * 2004-09-17 2006-03-23 Ebert Robert F Electronic software distribution method and system using a digital rights management method based on hardware identification
EP1736475A1 (en) * 2005-06-21 2006-12-27 Ferrer Internacional, S.A. Halogenated pyrazolo[1,5-a]pyrimidines, processes, uses, compositions and intermediates

Also Published As

Publication number Publication date
AU2007306318A1 (en) 2008-04-17
JP2010505913A (ja) 2010-02-25
AU2007306318B2 (en) 2012-07-05
EP2081934A1 (en) 2009-07-29
HK1130250A1 (en) 2009-12-24
CA2664900C (en) 2015-07-07
NO342009B1 (no) 2018-03-12
AR065831A1 (es) 2009-07-08
US20100048896A1 (en) 2010-02-25
PL2081934T3 (pl) 2011-08-31
DK2081934T3 (da) 2011-07-11
KR20090077806A (ko) 2009-07-15
KR101409573B1 (ko) 2014-06-19
UY30619A1 (es) 2008-03-31
CA2664900A1 (en) 2008-04-17
CN101573362A (zh) 2009-11-04
DE602007013596D1 (de) 2011-05-12
CN101573362B (zh) 2012-06-27
SI2081934T1 (sl) 2011-07-29
NO20091624L (no) 2009-05-07
BRPI0717836A2 (pt) 2014-05-20
RU2404984C1 (ru) 2010-11-27
CL2007002929A1 (es) 2008-05-16
WO2008043799A1 (en) 2008-04-17
ATE503758T1 (de) 2011-04-15
TW200825085A (en) 2008-06-16
EP1956021A1 (en) 2008-08-13
PT2081934E (pt) 2011-06-29
JP5270555B2 (ja) 2013-08-21
ES2362631T3 (es) 2011-07-08
US8008486B2 (en) 2011-08-30
HK1134924A1 (en) 2010-05-20
TWI425000B (zh) 2014-02-01
EP2081934B1 (en) 2011-03-30

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