MA30351B1 - Composes de tetrahydropyridothienopyrimidine et leurs procedes d'utilisation - Google Patents
Composes de tetrahydropyridothienopyrimidine et leurs procedes d'utilisationInfo
- Publication number
- MA30351B1 MA30351B1 MA31320A MA31320A MA30351B1 MA 30351 B1 MA30351 B1 MA 30351B1 MA 31320 A MA31320 A MA 31320A MA 31320 A MA31320 A MA 31320A MA 30351 B1 MA30351 B1 MA 30351B1
- Authority
- MA
- Morocco
- Prior art keywords
- compounds
- methods
- tetrahydropyridothienopyrimidine
- pharmaceutical compositions
- variables
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 239000008194 pharmaceutical composition Substances 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicinal Preparation (AREA)
Abstract
La présente invention concerne un composé de la Formule (I), Dans laquelle les variables sont telles que divulgué dans le mémoire descriptif, des compositions pharmaceutiques contenant lesdits composés, des procédés de fabrication des composés et des compositions pharmaceutiques et des procédés d'utilisation des composés et des compositions pharmaceutiques pour le traitement ou la prévention d'affections, en particulier du cancer.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78414606P | 2006-03-20 | 2006-03-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA30351B1 true MA30351B1 (fr) | 2009-04-01 |
Family
ID=38523058
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA31320A MA30351B1 (fr) | 2006-03-20 | 2008-10-20 | Composes de tetrahydropyridothienopyrimidine et leurs procedes d'utilisation |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US8501755B2 (fr) |
| EP (1) | EP2001890B1 (fr) |
| JP (1) | JP5282026B2 (fr) |
| KR (1) | KR20080110834A (fr) |
| CN (1) | CN101448840B (fr) |
| AR (1) | AR059901A1 (fr) |
| AT (1) | ATE495179T1 (fr) |
| AU (1) | AU2007227317A1 (fr) |
| BR (1) | BRPI0711045A2 (fr) |
| CA (1) | CA2647036C (fr) |
| CR (1) | CR10304A (fr) |
| DE (1) | DE602007011906D1 (fr) |
| DO (1) | DOP2007000053A (fr) |
| EC (1) | ECSP088749A (fr) |
| ES (1) | ES2357654T3 (fr) |
| GT (1) | GT200800187A (fr) |
| IL (1) | IL194028A0 (fr) |
| MA (1) | MA30351B1 (fr) |
| MX (1) | MX2008012006A (fr) |
| NZ (1) | NZ571326A (fr) |
| PA (1) | PA8719401A1 (fr) |
| PE (1) | PE20080144A1 (fr) |
| RU (1) | RU2008141239A (fr) |
| SV (1) | SV2008003032A (fr) |
| TN (1) | TNSN08370A1 (fr) |
| TW (1) | TW200804397A (fr) |
| UY (1) | UY30220A1 (fr) |
| WO (1) | WO2007109279A2 (fr) |
| ZA (1) | ZA200808017B (fr) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2431927B (en) | 2005-11-04 | 2010-03-17 | Amira Pharmaceuticals Inc | 5-Lipoxygenase-activating protein (FLAP) inhibitors |
| US7977359B2 (en) | 2005-11-04 | 2011-07-12 | Amira Pharmaceuticals, Inc. | 5-lipdxygenase-activating protein (FLAP) inhibitors |
| WO2009033581A1 (fr) * | 2007-09-14 | 2009-03-19 | Bayer Schering Pharma Aktiengesellschaft | Composés tricycliques substitués et leurs procédés d'utilisation |
| US8507502B2 (en) | 2008-11-10 | 2013-08-13 | National Health Research Institutes | Fused bicyclic and tricyclic pyrimidine compounds as tyrosine kinase inhibitors |
| JP2015513317A (ja) * | 2012-01-25 | 2015-05-07 | プロテオステイシス セラピューティクス，インコーポレイテッド | プロテアソーム活性を増強する化合物 |
| US20170107229A1 (en) * | 2014-05-26 | 2017-04-20 | Bayer Pharma Aktiengesellschaft | Substituted tetrahydropyridothienopyrimidines |
| EP3111960B1 (fr) * | 2015-07-03 | 2019-12-11 | Kyoto University | Agent d'imagerie de diagnostic de médecine nucléaire |
| EP3474846B1 (fr) | 2016-06-22 | 2022-11-30 | Vanderbilt University | Modulateurs allostériques positifs du récepteur muscarinique de l'acétylcholine m4 |
| MA46899A (fr) | 2016-11-07 | 2021-04-14 | Univ Vanderbilt | Modulateurs allostériques positifs du récepteur muscarinique de l'acétylcholine m4 |
| JP7099725B2 (ja) | 2016-11-07 | 2022-07-12 | ヴァンダービルト ユニヴァーシティ | ムスカリン性アセチルコリンレセプターｍ４のポジティブアロステリック調節因子 |
| EP3534901B1 (fr) | 2016-11-07 | 2022-06-22 | Vanderbilt University | Modulateurs allostériques positifs du récepteur muscarinique à l'acétylcholine m4 |
| TW201930311A (zh) | 2017-12-05 | 2019-08-01 | 泛德比爾特大學 | 蕈毒鹼型乙醯膽鹼受體m4之正向別構調節劑 |
| US11376254B2 (en) | 2017-12-05 | 2022-07-05 | Vanderbilt University | Positive allosteric modulators of the muscarinic acetylcholine receptor M4 |
| WO2020191151A1 (fr) * | 2019-03-19 | 2020-09-24 | Oncovalent Therapeutics Inc. | Composés inhibiteurs de sumo et leurs utilisations |
| WO2023015240A1 (fr) * | 2021-08-05 | 2023-02-09 | Bristol-Myers Squibb Company | Composés pyrimidines fusionnés tricycliques destinés à être utilisés en tant qu'inhibiteurs de her2 |
| CN114736154B (zh) * | 2022-03-15 | 2023-07-21 | 安庆朗坤药业有限公司 | N-（3-氯-4-（2-吡啶甲氧基）苯基）-2-氰基乙酰胺的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20010105399A (ko) * | 1999-03-30 | 2001-11-28 | 쓰끼하시 다미까따 | 티에노피리미딘 화합물 및 그의 염, 및 그들의 제조 방법 |
| DE19944604A1 (de) * | 1999-09-17 | 2001-03-22 | Merck Patent Gmbh | Aminderivate |
| US6608053B2 (en) * | 2000-04-27 | 2003-08-19 | Yamanouchi Pharmaceutical Co., Ltd. | Fused heteroaryl derivatives |
| WO2003035653A1 (fr) * | 2001-10-26 | 2003-05-01 | Nippon Soda Co.,Ltd. | Compose pyridothienopyrimidine et son sel |
| ES2280040T3 (es) * | 2003-07-24 | 2007-09-01 | Bayer Pharmaceuticals Corporation | Compuestos de tetrahidrobenzotienopirimidinamina sustituidos utiles para tratar trastornos hiperproliferativos. |
-
2007
- 2007-03-15 AR ARP070101057A patent/AR059901A1/es not_active Application Discontinuation
- 2007-03-19 TW TW096109309A patent/TW200804397A/zh unknown
- 2007-03-19 UY UY30220A patent/UY30220A1/es not_active Application Discontinuation
- 2007-03-19 PE PE2007000292A patent/PE20080144A1/es not_active Application Discontinuation
- 2007-03-20 BR BRPI0711045-6A patent/BRPI0711045A2/pt not_active IP Right Cessation
- 2007-03-20 DE DE602007011906T patent/DE602007011906D1/de active Active
- 2007-03-20 US US12/225,285 patent/US8501755B2/en not_active Expired - Fee Related
- 2007-03-20 KR KR1020087025480A patent/KR20080110834A/ko not_active Ceased
- 2007-03-20 MX MX2008012006A patent/MX2008012006A/es active IP Right Grant
- 2007-03-20 AT AT07753547T patent/ATE495179T1/de not_active IP Right Cessation
- 2007-03-20 WO PCT/US2007/006927 patent/WO2007109279A2/fr not_active Ceased
- 2007-03-20 PA PA20078719401A patent/PA8719401A1/es unknown
- 2007-03-20 DO DO2007000053A patent/DOP2007000053A/es unknown
- 2007-03-20 ES ES07753547T patent/ES2357654T3/es active Active
- 2007-03-20 JP JP2009501517A patent/JP5282026B2/ja not_active Expired - Fee Related
- 2007-03-20 NZ NZ571326A patent/NZ571326A/en not_active IP Right Cessation
- 2007-03-20 AU AU2007227317A patent/AU2007227317A1/en not_active Abandoned
- 2007-03-20 CA CA2647036A patent/CA2647036C/fr not_active Expired - Fee Related
- 2007-03-20 CN CN2007800178021A patent/CN101448840B/zh not_active Expired - Fee Related
- 2007-03-20 RU RU2008141239/04A patent/RU2008141239A/ru not_active Application Discontinuation
- 2007-03-20 EP EP07753547A patent/EP2001890B1/fr not_active Not-in-force
-
2008
- 2008-09-11 IL IL194028A patent/IL194028A0/en unknown
- 2008-09-18 SV SV2008003032A patent/SV2008003032A/es not_active Application Discontinuation
- 2008-09-18 GT GT200800187A patent/GT200800187A/es unknown
- 2008-09-18 ZA ZA200808017A patent/ZA200808017B/xx unknown
- 2008-09-19 EC EC2008008749A patent/ECSP088749A/es unknown
- 2008-09-19 CR CR10304A patent/CR10304A/es not_active Application Discontinuation
- 2008-09-22 TN TNP2008000370A patent/TNSN08370A1/en unknown
- 2008-10-20 MA MA31320A patent/MA30351B1/fr unknown
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