| Computational methods in drug discovery G Sliwoski, S Kothiwale, J Meiler, EW Lowe Jr Pharmacological reviews 66 (1), 334-395, 2014 | 2731 | 2014 |
| Protein structure prediction using Rosetta CA Rohl, CEM Strauss, KMS Misura, D Baker Methods in enzymology 383, 66-93, 2004 | 2336 | 2004 |
| ROSETTA3: an object-oriented software suite for the simulation and design of macromolecules A Leaver-Fay, M Tyka, SM Lewis, OF Lange, J Thompson, R Jacak, ... Methods in enzymology 487, 545-574, 2011 | 2305 | 2011 |
| Potently neutralizing and protective human antibodies against SARS-CoV-2 SJ Zost, P Gilchuk, JB Case, E Binshtein, RE Chen, JP Nkolola, A Schäfer, ... Nature 584 (7821), 443-449, 2020 | 1230 | 2020 |
| Recognition dynamics up to microseconds revealed from an RDC-derived ubiquitin ensemble in solution OF Lange, NA Lakomek, C Fares, GF Schroder, KFA Walter, S Becker, ... science 320 (5882), 1471-1475, 2008 | 1213 | 2008 |
| Macromolecular modeling and design in Rosetta: recent methods and frameworks JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ... Nature methods 17 (7), 665-680, 2020 | 934 | 2020 |
| RosettaScripts: a scripting language interface to the Rosetta macromolecular modeling suite SJ Fleishman, A Leaver-Fay, JE Corn, EM Strauch, SD Khare, N Koga, ... PloS one 6 (6), e20161, 2011 | 759 | 2011 |
| ROSETTALIGAND: Protein–small molecule docking with full side‐chain flexibility J Meiler, D Baker Proteins: Structure, Function, and Bioinformatics 65 (3), 538-548, 2006 | 661 | 2006 |
| Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator H Wu, C Wang, KJ Gregory, GW Han, HP Cho, Y Xia, CM Niswender, ... Science 344 (6179), 58-64, 2014 | 644 | 2014 |
| Practically Useful: What the Rosetta Protein Modeling Suite Can Do for You KW Kaufmann, GH Lemmon, SL DeLuca, JH Sheehan, J Meiler Biochemistry 49 (14), 2987-2998, 2010 | 587 | 2010 |
| Solvent accessible surface area approximations for rapid and accurate protein structure prediction E Durham, B Dorr, N Woetzel, R Staritzbichler, J Meiler Journal of molecular modeling 15 (9), 1093-1108, 2009 | 501 | 2009 |
| New algorithms and an in silico benchmark for computational enzyme design A Zanghellini, L Jiang, AM Wollacott, G Cheng, J Meiler, EA Althoff, ... Protein Science 15 (12), 2785-2794, 2006 | 495 | 2006 |
| Sampling alternative conformational states of transporters and receptors with AlphaFold2 D Del Alamo, D Sala, HS Mchaourab, J Meiler Elife 11, e75751, 2022 | 485 | 2022 |
| Model-free approach to the dynamic interpretation of residual dipolar couplings in globular proteins J Meiler, JJ Prompers, W Peti, C Griesinger, R Brüschweiler Journal of the American Chemical Society 123 (25), 6098-6107, 2001 | 342 | 2001 |
| Generation and evaluation of dimension-reduced amino acid parameter representations by artificial neural networks J Meiler, M Müller, A Zeidler, F Schmäschke Molecular modeling annual 7 (9), 360-369, 2001 | 341 | 2001 |
| Opportunities and challenges in the discovery of allosteric modulators of GPCRs for treating CNS disorders PJ Conn, CW Lindsley, J Meiler, CM Niswender Nature reviews Drug discovery 13 (9), 692-708, 2014 | 307 | 2014 |
| Coupled prediction of protein secondary and tertiary structure J Meiler, D Baker Proceedings of the National Academy of Sciences 100 (21), 12105-12110, 2003 | 256 | 2003 |
| Rosetta predictions in CASP5: successes, failures, and prospects for complete automation P Bradley, D Chivian, J Meiler, KMS Misura, CA Rohl, WR Schief, ... Proteins: Structure, Function, and Bioinformatics 53 (S6), 457-468, 2003 | 252 | 2003 |
| Structure of KCNE1 and implications for how it modulates the KCNQ1 potassium channel C Kang, C Tian, FD Sönnichsen, JA Smith, J Meiler, AL George Jr, ... Biochemistry 47 (31), 7999-8006, 2008 | 248 | 2008 |
| Protocols for molecular modeling with Rosetta3 and RosettaScripts BJ Bender, A Cisneros III, AM Duran, JA Finn, D Fu, AD Lokits, BK Mueller, ... Biochemistry 55 (34), 4748-4763, 2016 | 245 | 2016 |
Jonathan H. SheehanAssociate Professor, Washington Univ. School of Medicine in St. LouisVerified email at wustl.edu
