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Jordi Pujols
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DisProt 7.0: a major update of the database of disordered proteins
D Piovesan, F Tabaro, I Mičetić, M Necci, F Quaglia, CJ Oldfield, ...
Nucleic acids research 45 (D1), D219-D227, 2017
3522017
AGGRESCAN3D (A3D): server for prediction of aggregation properties of protein structures
R Zambrano, M Jamroz, A Szczasiuk, J Pujols, S Kmiecik, S Ventura
Nucleic acids research 43 (W1), W306-W313, 2015
2852015
DisProt: intrinsic protein disorder annotation in 2020
A Hatos, B Hajdu-Soltész, AM Monzon, N Palopoli, L Álvarez, ...
Nucleic acids research 48 (D1), D269-D276, 2020
2832020
Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons
J Pujols, S Peña-Díaz, DF Lázaro, F Peccati, F Pinheiro, D González, ...
Proceedings of the National Academy of Sciences 115 (41), 10481-10486, 2018
2682018
Aggrescan3D (A3D) 2.0: prediction and engineering of protein solubility
A Kuriata, V Iglesias, J Pujols, M Kurcinski, S Kmiecik, S Ventura
Nucleic acids research 47 (W1), W300-W307, 2019
1902019
DisProt in 2022: improved quality and accessibility of protein intrinsic disorder annotation
F Quaglia, B Mészáros, E Salladini, A Hatos, R Pancsa, LB Chemes, ...
Nucleic acids research 50 (D1), D480-D487, 2022
1802022
High-throughput screening methodology to identify alpha-synuclein aggregation inhibitors
J Pujols, S Peña-Díaz, M Conde-Giménez, F Pinheiro, S Navarro, ...
International journal of molecular sciences 18 (3), 478, 2017
922017
C-mannosylation supports folding and enhances stability of thrombospondin repeats
A Shcherbakova, M Preller, MH Taft, J Pujols, S Ventura, B Tiemann, ...
Elife 8, e52978, 2019
812019
α-Helical peptidic scaffolds to target α-synuclein toxic species with nanomolar affinity
J Santos, P Gracia, S Navarro, S Peña-Díaz, J Pujols, N Cremades, ...
Nature communications 12 (1), 3752, 2021
732021
Computational prediction of protein aggregation: Advances in proteomics, conformation-specific algorithms and biotechnological applications
J Santos, J Pujols, I Pallarès, V Iglesias, S Ventura
Computational and structural biotechnology journal 18, 1403-1413, 2020
732020
Chemical chaperones as novel drugs for Parkinson’s disease
J Pujols, S Peña-Díaz, I Pallarès, S Ventura
Trends in molecular medicine 26 (4), 408-421, 2020
612020
Dual binding mode of metallacarborane produces a robust shield on proteins
I Fuentes, J Pujols, C Viñas, S Ventura, F Teixidor
Chemistry–A European Journal 25 (55), 12820-12829, 2019
482019
ZPD-2, a small compound that inhibits α-synuclein amyloid aggregation and its seeded polymerization
S Peña-Díaz, J Pujols, M Conde-Giménez, A Čarija, E Dalfo, J García, ...
Frontiers in molecular neuroscience 12, 306, 2019
462019
Biasing the native α-synuclein conformational ensemble towards compact states abolishes aggregation and neurotoxicity
A Carija, F Pinheiro, J Pujols, IC Brás, DF Lázaro, C Santambrogio, ...
Redox biology 22, 101135, 2019
372019
A targetable N-terminal motif orchestrates α-synuclein oligomer-to-fibril conversion
J Santos, J Cuellar, I Pallarès, EJ Byrd, A Lends, F Moro, ...
Journal of the American Chemical Society 146 (18), 12702-12711, 2024
29*2024
The small aromatic compound SynuClean-D inhibits the aggregation and seeded polymerization of multiple α-synuclein strains
S Peña-Díaz, J Pujols, E Vasili, F Pinheiro, J Santos, ...
Journal of Biological Chemistry 298 (5), 2022
262022
Inhibition of α-synuclein aggregation and mature fibril disassembling with a minimalistic compound, ZPDm
S Peña-Díaz, J Pujols, F Pinheiro, J Santos, I Pallarés, S Navarro, ...
Frontiers in Bioengineering and Biotechnology 8, 588947, 2020
232020
Disulfide driven folding for a conditionally disordered protein
H Fraga, J Pujols, M Gil-Garcia, A Roque, G Bernardo-Seisdedos, ...
Scientific reports 7 (1), 16994, 2017
222017
A spatiotemporally defined in vitro microenvironment for controllable signal delivery and drug screening
CT Kuo, HK Liu, GS Huang, CH Chang, CL Chen, KC Chen, RYJ Huang, ...
Analyst 139 (19), 4846-4854, 2014
222014
Small molecules to prevent the neurodegeneration caused by α-synuclein aggregation
S Pena-Diaz, J Pujols, S Ventura
Neural Regeneration Research 15 (12), 2260-2261, 2020
212020
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Articles 1–20