| Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons J Pujols, S Peña-Díaz, DF Lázaro, F Peccati, F Pinheiro, D González, ... Proceedings of the National Academy of Sciences 115 (41), 10481-10486, 2018 | 268 | 2018 |
| DisProt in 2022: improved quality and accessibility of protein intrinsic disorder annotation F Quaglia, B Mészáros, E Salladini, A Hatos, R Pancsa, LB Chemes, ... Nucleic acids research 50 (D1), D480-D487, 2022 | 180 | 2022 |
| High-throughput screening methodology to identify alpha-synuclein aggregation inhibitors J Pujols, S Peña-Díaz, M Conde-Giménez, F Pinheiro, S Navarro, ... International journal of molecular sciences 18 (3), 478, 2017 | 92 | 2017 |
| α-Helical peptidic scaffolds to target α-synuclein toxic species with nanomolar affinity J Santos, P Gracia, S Navarro, S Peña-Díaz, J Pujols, N Cremades, ... Nature communications 12 (1), 3752, 2021 | 73 | 2021 |
| Chemical chaperones as novel drugs for Parkinson’s disease J Pujols, S Peña-Díaz, I Pallarès, S Ventura Trends in molecular medicine 26 (4), 408-421, 2020 | 61 | 2020 |
| Development of small molecules targeting α-synuclein aggregation: a promising strategy to treat Parkinson’s disease S Peña-Díaz, J García-Pardo, S Ventura Pharmaceutics 15 (3), 839, 2023 | 49 | 2023 |
| Functional amyloids: the biomaterials of tomorrow? S Peña‐Díaz, WP Olsen, H Wang, DE Otzen Advanced Materials 36 (18), 2312823, 2024 | 48 | 2024 |
| ZPD-2, a small compound that inhibits α-synuclein amyloid aggregation and its seeded polymerization S Peña-Díaz, J Pujols, M Conde-Giménez, A Čarija, E Dalfo, J García, ... Frontiers in molecular neuroscience 12, 306, 2019 | 46 | 2019 |
| One ring is sufficient to inhibit α-synuclein aggregation S Peña-Díaz, S Ventura Neural Regeneration Research 17 (3), 508-511, 2022 | 39 | 2022 |
| Rational design of small molecules able to inhibit α-synuclein amyloid aggregation for the treatment of Parkinson’s disease S Vittorio, I Adornato, R Gitto, S Peña-Díaz, S Ventura, L De Luca Journal of enzyme inhibition and medicinal chemistry 35 (1), 1727-1735, 2020 | 28 | 2020 |
| The small aromatic compound SynuClean-D inhibits the aggregation and seeded polymerization of multiple α-synuclein strains S Peña-Díaz, J Pujols, E Vasili, F Pinheiro, J Santos, ... Journal of Biological Chemistry 298 (5), 2022 | 26 | 2022 |
| Inhibition of α-synuclein aggregation and mature fibril disassembling with a minimalistic compound, ZPDm S Peña-Díaz, J Pujols, F Pinheiro, J Santos, I Pallarés, S Navarro, ... Frontiers in Bioengineering and Biotechnology 8, 588947, 2020 | 23 | 2020 |
| Small molecules to prevent the neurodegeneration caused by α-synuclein aggregation S Pena-Diaz, J Pujols, S Ventura Neural Regeneration Research 15 (12), 2260-2261, 2020 | 21 | 2020 |
| Discovery of neuroprotective agents based on a 5-(4-Pyridinyl)-1, 2, 4-triazole scaffold R Gitto, S Vittorio, F Bucolo, S Peña-Díaz, R Siracusa, S Cuzzocrea, ... ACS Chemical Neuroscience 13 (5), 581-586, 2022 | 19 | 2022 |
| Design, synthesis and structure-activity evaluation of novel 2-pyridone-based inhibitors of α-synuclein aggregation with potentially improved BBB permeability A Mahía, S Pena-Diaz, S Navarro, JJ Galano-Frutos, I Pallarés, J Pujols, ... Bioorganic Chemistry 117, 105472, 2021 | 19 | 2021 |
| AGGRESCAN3D: toward the prediction of the aggregation propensities of protein structures J Pujols, S Peña-Díaz, S Ventura Computational Drug Discovery and Design, 427-443, 2018 | 18 | 2018 |
| Ligand-based discovery of a small molecule as inhibitor of α-synuclein amyloid formation L De Luca, S Vittorio, S Peña-Díaz, G Pitasi, M Fornt-Suñé, F Bucolo, ... International journal of molecular sciences 23 (23), 14844, 2022 | 14 | 2022 |
| Interactions between pathological and functional amyloid: A match made in Heaven or Hell? DE Otzen, S Peña-Díaz, J Widmann, AOH Daugberg, Z Zhang, Y Jiang, ... Molecular aspects of medicine 103, 101351, 2025 | 11 | 2025 |
| CsgA gatekeeper residues control nucleation but not stability of functional amyloid WP Olsen, G Courtade, S Peña‐Díaz, M Nagaraj, TV Sønderby, ... Protein Science 33 (10), e5178, 2024 | 8 | 2024 |
| The small molecule ZPD‐2 inhibits the aggregation and seeded polymerisation of C‐terminally truncated α‐Synuclein S Peña‐Díaz, S Ventura The FEBS Journal 291 (23), 5290-5304, 2024 | 4 | 2024 |
Salvador VenturaInstitute of Biotechnology and Biomedicine (IBB), Universitat Autonoma de BarcelonaVerified email at uab.es
